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Yuxiang Wang,Yunjie Gu,Wuhua Li,Xiangning He 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
In virtual vector control schemes for singlephase current-regulated voltage source inverters, a transient disturbance may be induced due to the time-delay in the virtual orthogonal signal. This disturbance deteriorates the dynamic current-tracking capability and power quality. A unified scalar model is developed to analyze the phenomenon. Based on this model, an improved control scheme with a pre-compensator is proposed to solve the problem. The pre-compensator reshapes the current commands so that the transient disturbance signal is eliminated while the desired response is unaffected. Experimental results of the proposed strategy are compared with the conventional solution to substantiate enhanced dynamic performance.
Synchronous Frequency Resonance of Virtual Synchronous Generators and Damping Control
Jinhua Wang,Yuxiang Wang,Yunjie Gu,Wuhua Li,Xiangning He 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
The Virtual Synchronous Generator (VSG) is an effective solution for high-penetration renewable energy sources integrated into the power system. Although the VSG has a similar behavior as the conventional synchronous generator, the fast and flexible control capability of converters may give rise to some specific characteristics. In this paper, it is explained that flux dynamics may induce synchronous frequency resonance in VSGs, which possibly leads to power-angle oscillations. A precise small-signal model is established to investigate the synchronous frequency resonance phenomenon. Based on this model, two damping control methods are proposed, which suppress the resonance through increasing the virtual mechanical inertia or adding virtual electrical resistance. The effectiveness of the theoretical conclusions is verified by simulation and experimental results.
Xinjie Gao,Heng Yang,Weiping Xiao,Jiabin Su,Yuwen Zhang,He Wang,Wei Ni,Yuxiang Gu 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4
Background: Despite limited efficiency, modulation of microglia/macrophages has shown to attenuate neuroinflammation after intracerebral hemorrhage (ICH). In this context, we evaluated the efficacy of modified exosomal signal regulatory protein α (SIRPα) variants (SIRPα-v Exos) in microglia/macrophages and neuroinflammation-associated white matter injury after ICH. Methods: SIRPα-v Exos were engineered to block CD47-SIRPα interactions. After obtaining SIRPα-v Exos from lentivirus-infected mesenchymal stem cells, C57BL/6 mice suffering from ICH underwent consecutive intravenous injections of SIRPα-v Exos (6 mg/kg) for 14 days. Afterwards, the volume of hematoma and neurological dysfunctions were assessed in mice continuously until 35 days after ICH. In addition, demyelination, electrophysiology and neuroinflammation were evaluated. Furthermore, the mechanisms of microglial regulation by SIRPα-v Exos were investigated in vitro under coculture conditions. Results: The results demonstrated that the clearance of hematoma in mice suffering from ICH was accelerated after SIRPα-v Exo treatment. SIRPα-v Exos improved long-term neurological dysfunction by ameliorating white matter injury. In addition, SIRPα-v Exos recruited regulatory T cells (Tregs) to promote M2 polarization of microglia/macrophages in the peri-hematoma tissue. In vitro experiments further showed that SIRPα-v Exos regulated primary microglia in a direct and indirect manner in synergy with Tregs. Conclusion: Our studies revealed that SIRPα-v Exos could accelerate the clearance of hematoma and ameliorate secondary white matter injury after ICH through regulation of microglia/macrophages. SIRPα-v Exos may become a promising treatment for ICH in clinical practice.