A modified heteropoly acid catalyst with cetyltrimethylammonium bromide for methacrolein to methacrylic acid

Yun-Li Cao,Lei Wang,Li-Long Zhou,Bao-Hua Xu,Yan-Yan Diao,Suojiang Zhang 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.65 No.-

A novel type of heteropolyacids, CTAB-CsH3PMo11VO40 (CTA-CsPAV), was developed by a method of emulsion synthesis using cetyltrimethyl ammonium bromide (CTAB) as the structure promoter, which was applied as a catalyst in the oxidation of methacrolein (MAL) to methacrylic acid (MAA) with fixed-bed reactor. The structure and property of CTA-CsPAV were characterized by FT-IR, XRD, nitrogen adsorption-desorption, NH3-TPD, SEM, XPS, and so on. The structure-performance relationship of CTA-CsPAV was systematically studied, wherein the influence of surface area, acidity, redox property of CTA-CsPAV were focused and discussed. Importantly, the long-term performance of CTA-CsPAV was also investigated.

Concurrent Pleural and Pericardial Involvement in a Patient With De Novo Pure Erythroid Leukemia

Zhang Yun,Li Kechao,Li Xue,Wang Hui,Li Ting,Long Fang 대한진단검사의학회 2024 Annals of Laboratory Medicine Vol.44 No.2

Correlations of Tumor-associated Macrophage Subtypes with Liver Metastases of Colorectal Cancer

Cui, Yun-Long,Li, Hui-Kai,Zhou, Hong-Yuan,Zhang, Ti,Li, Qiang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

Objective: This work aimed to investigate the correlations of tumor-associated macrophages (TAMs) and their subtypes M1 and M2 with liver metastasis of colorectal cancer, and provide useful references for seeking predictors of liver metastasis and studying mechanisms. Methods: 120 patients with colorectal cancer from 2000 to 2009 were divided into low, middle and high liver metastasis groups (group A, B and C, respectively). S-P immunohistochemical staining and microscopic observation were conducted to compare expression in CD68-positive cells (TAMs), CD80-positive cells (M1) and CD163-positive cells (M2) in three groups. Correlations of TAMs, M1, M2, and M2/M1 ratio with clinical and pathological parameters were analyzed. Results: With increase of liver metastatic ability, the number of TAMs decreased gradually, with no significant difference between any two of the three groups (P > 0.05), while the numbers of M1 and M2 were significantly decreased and increased, respectively, with significant difference between any two of three groups (P < 0.05 or P < 0.01). In addition, the M2/M1 ratio increased with increase of liver metastatic ability (P < 0.01). There was no statistical significance of correlation of TAMs with each clinical and pathological parameter. M1 was negatively related with lymphatic metastasis and liver metastatic ability. M2 was positively correlated with preoperative CEA level, lymphatic metastasis, tumor differentiation degree and liver metastatic ability. The same was the case for the M2/M1 ratio. Conclusions: Effects of TAMs on liver metastasis of colorectal cancer do not depend on the total number of TAMs, but on the number and proportion of functional subtypes M1 and M2. M2 number and M2/M1 ratio are more accurate predictors for liver metastasis of colorectal cancer.

NH₂-Fe-MILs for effective adsorption and Fenton-like degradation of imidacloprid: Removal performance and mechanism investigation

Mao-Long Chen,Tian-Hui Lu,Ling-Li Long,Zhou Xu,Li Ding,Yun-Hui Cheng 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.2

This investigation enables amino-functionalized metal–organic frameworks (MOFs) materials for the removal of imidacloprid (IMC). Two Fe-based MOF materials of NH₂-MIL-88B(Fe) and NH₂-MIL-101(Fe) both exhibited high adsorption capacity and Fenton-like degradation ability for IMC which were utilized to remove IMC from aqueous solution. Although the adsorption capacity of NH₂-MIL-101(Fe) was higher than that of NH₂-MIL-88(Fe), the degradation abilities of both MOF materials were similar. The removal efficiencies were evaluated through several basic studies, including concentrations of catalyst (0.12-0.3 g/L) and IMC (20-100 mg/L), pH of solution (3-11), and amounts of 30% H₂O₂ (0-2.0 μL/mL). By optimizing the above factors, the total removal ratio of IMC by NH₂-MIL-88B(Fe) was as high as 93%, whereas the removal ratio of NH₂-MIL-101(Fe) was 97%. Moreover, these MOF materials were proven to be stable and recyclable. The free radical quenching experiment and density functional theory calculation were applied to research the removal mechanism, and the hydroxyl radicals (·OH) was found to be the key active intermediate. The high catalytic efficiency can be attributed to the synergy of the Fe<SUP>3+</SUP>/Fe<SUP>2+</SUP> redox cycle.

Value of contrast-enhanced ultrasonography in microwave ablation treatment of symptomatic focal uterine adenomyosis

Xiao-Long Li,Jia-Xin Li,Song-Yuan Yu,Pei-Li Fan,Yun-Jie Jin,Er-Jiao Xu,Sai-Nan Guan,Er-Ya Deng,Qiu-Yan Li,Zheng-Biao Ji,Jiu-Ling Qi,Hui-Xiong Xu,China Alliance of Multi-Center Clinical Study for Ultra 대한초음파의학회 2024 ULTRASONOGRAPHY Vol.43 No.1

Purpose: This study evaluated the value of contrast-enhanced ultrasonography (CEUS) in the ultrasound-guided microwave ablation (MWA) treatment of symptomatic focal uterine adenomyosis.Methods: This retrospective study was conducted between March 2020 and January 2023, enrolling 52 patients with symptomatic focal uterine adenomyosis who had undergone MWA. All patients were examined with CEUS before and after MWA. The non-perfused volume (NPV) was compared between CEUS and dynamic contrast-enhanced magnetic resonance imaging (DCEMRI) following ablation. Therapeutic efficacy and safety were evaluated at 3-, 6-, and 12-month follow-ups. Additionally, this study explored the correlations between pre-treatment CEUS features and a volume reduction ratio indicating sufficient ablation, defined as 50% or more at the 3-month follow-up.Results: No significant differences in NPV were noted between CEUS and DCE-MRI immediately after MWA and during follow-up (all P>0.05). At the 3-month follow-up, the median VRRs for the uterus and adenomyosis were 33.2% and 63.9%, respectively. Sufficient ablation was achieved in 69.2% (36/52) of adenomyosis cases, while partial ablation was observed in the remaining 30.8% (16/52). The identification of non-enhancing areas on pre-treatment CEUS was associated with sufficient ablation (P=0.016). At the 12-month follow-up, significant decreases were observed in both the uterine and adenomyosis volumes (all P<0.001). Dysmenorrhea and menorrhagia were significantly alleviated at 12 months, and no major complications were encountered.Conclusion: CEUS can be used to evaluate the ablation zone of focal adenomyosis that has been treated with MWA, similarly to DCE-MRI. The identification of non-enhancing areas on pretreatment CEUS indicates satisfactory treatment outcomes. Purpose: This study evaluated the value of contrast-enhanced ultrasonography (CEUS) in the ultrasound-guided microwave ablation (MWA) treatment of symptomatic focal uterine adenomyosis. Methods: This retrospective study was conducted between March 2020 and January 2023, enrolling 52 patients with symptomatic focal uterine adenomyosis who had undergone MWA. All patients were examined with CEUS before and after MWA. The non-perfused volume (NPV) was compared between CEUS and dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) following ablation. Therapeutic efficacy and safety were evaluated at 3-, 6-, and 12-month follow-ups. Additionally, this study explored the correlations between pre-treatment CEUS features and a volume reduction ratio indicating sufficient ablation, defined as 50% or more at the 3-month follow-up. Results: No significant differences in NPV were noted between CEUS and DCE-MRI immediately after MWA and during follow-up (all P>0.05). At the 3-month follow-up, the median VRRs for the uterus and adenomyosis were 33.2% and 63.9%, respectively. Sufficient ablation was achieved in 69.2% (36/52) of adenomyosis cases, while partial ablation was observed in the remaining 30.8% (16/52). The identification of non-enhancing areas on pre-treatment CEUS was associated with sufficient ablation (P=0.016). At the 12-month follow-up, significant decreases were observed in both the uterine and adenomyosis volumes (all P<0.001). Dysmenorrhea and menorrhagia were significantly alleviated at 12 months, and no major complications were encountered. Conclusion: CEUS can be used to evaluate the ablation zone of focal adenomyosis that has been treated with MWA, similarly to DCE-MRI. The identification of non-enhancing areas on pre- treatment CEUS indicates satisfactory treatment outcomes.

MicroRNA-328 Inhibits Proliferation of Human Melanoma Cells by Targeting TGFB2

Li, Jing-Rong,Wang, Jian-Qin,Gong, Qing,Fang, Rui-Hua,Guo, Yun-Long Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.4

Some microRNAs (miRNAs) have been shown to act as oncogenes or tumor suppressor genes in human melanomas. miR-328 is upregulated in blood cells of melanoma patients compared to in healthy controls. This suggests a role for miR-328 in melanoma that warrants investigation. In this study, we demonstrated miR-328 levels to be dramatically decreased in human melanoma cell lines. Moreover, forced expression of miR-328 inhibited proliferation and induced G1-phase arrest of the SK-MEL-1 melanoma cell line. We identified TGFB2 as a direct target gene for miR-328 using a fluorescent reporter assay and western blotting. Levels of TGFB2 were dramatically increased in human melanoma cell lines and were inversely correlated with the miR-328 expression level. Our findings provide new insights into the mechanisms of human melanoma development, indicating that miR-328 has therapeutic potential for this disease.

Novel Filtering Power Divider with External Isolation Resistors

Yun Long Lu,Shun Wang,Gao-Le Dai,Kai Li 한국전자통신연구원 2015 ETRI Journal Vol.37 No.1

In this paper, a novel filtering power divider with external isolation resistors is presented. The proposed power divider can be considered as an integration of a bandpass filter and a Gysel power divider. Based on the circuit topology, a high-order filtering power divider can be easily realized. Odd- and even-mode models are employed to analyze the filtering and power splitting functions. For demonstration, a third-order filtering power divider operating at 1.5 GHz is designed and implemented. The measured results exhibit an isolation between the output ports that is better than 20 dB at around the center frequency.

Numerical and experimental investigation on the diffuser optimization of a reactor coolant pump with orthogonal test approach

Long Yun,Zhu Rongsheng,Wang Dezhong,Yin Junlian,Li Tianbin 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.11

The diffuser of a reactor coolant pump was optimized using an orthogonal approach with numerical simulation to improve the pump hydraulic performance. Steady simulation was conducted by solving Reynolds-averaged Naiver-Stokes equations with the SST k-ω turbulence model using CFX code. The influence of the diffuser geometric parameters, namely, S, φ, α 4 , b 4 , δ 2 , R t and R 4 , on the pump performance were determined. L 18 (3 7 ) orthogonal table was chosen for the optimization process. Best indicators were determined, and range analysis of energy losses, head, and efficiency at the rated condition was performed. Optimal parameters of the diffuser were S = 490 mm, φ = 36°, α 4 = 30°, b 4 = 200 mm, δ 2 = 20 mm, R t = 5 mm and R 4 = 565 mm. The final design was experimentally tested. Simulation results showed more remarkable performance than the experimental result. However, the numerical predictions and experimental results were consistent, validating the design procedure. Loading of the impeller and diffuser blades was analyzed to investigate the direct impact on the hydrodynamic flow field. The head was 14.74 m, efficiency was 79.6 %, and efficiency of the prototype pump was 83.3 % when the model pump functioned at the rated conditions. Optimization results showed that efficiency and head were improved at the design condition.

Hypoxia Induced High Expression of Thioredoxin Interacting Protein (TXNIP) in Non-small Cell Lung Cancer and its Prognostic Effect

Li, Yan,Miao, Li-Yun,Xiao, Yong-Long,Huang, Mei,Yu, Min,Meng, Kui,Cai, Hou-Rong Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7

Although associations between thioredoxin interacting protein (TXNIP) and cancers have been recognized, the effects of TXNIP on non-small cell lung cancer (NSCLC) prognosis remained to be determined in detail. In addition, while hypoxia is a key characteristic of tumor cell growth microenvironment, the effect of hypoxia on TXNIP expression is controversial. In this study, formaldehyde fixed and paraffin embedded (FFPE) samples of 70 NSCLC patients who underwent resection between January 2010 and December 2011 were obtained. Evaluation of TXNIP and hypoxia inducible factor-$1{\alpha}$ ($HIF-1{\alpha}$) protein expression in FFPE samples was made by immunohistochemistry. By Kaplan-Meier method, patients with high TXNIP expression demonstrated a significantly shorter progression free survival (PFS) compared with those with low TXNIP expression (18.0 months, 95%CI: 11.7, 24.3 versus 23.0 months, 95%CI: 17.6, 28.4, P=0.02). High TXNIP expression level was also identified as an independent prognostic factor by Cox regression analysis (adjusted hazard ratio: 2.46; 95%CI: 1.08, 5.56; P=0.03). Furthermore, TXNIP expression was found to be significantly correlated with $HIF-1{\alpha}$ expression (Spearman correlation=0.67, P=0.000). To further confirm correlations, we established a tumor cell hypoxic culture model. Expression of TXNIP was up-regulated in all three NSCLC cell lines (A549, SPC-A1, and H1299) under hypoxic conditions. This study suggests that hypoxia induces increased TXNIP expression in NSCLC and high TXNIP expression could be a poor prognostic marker.

Anomalous Propagation Characteristics of an Airy Beam in Nonlocal Nonlinear Medium

Yun-Long Wu,Qin Ye,Li Shao 한국광학회 2021 Current Optics and Photonics Vol.5 No.2

The anomalous propagation characteristics of a single Airy beam in nonlocal nonlinear medium are investigated by utilizing the split-step Fourier-transform method. We show that besides the normal straight propagation trajectory, the breathing solitons formed by the interaction between Airy beam and nonlocal nonlinear medium can propagate along the sinusoidal trajectory, and the anomalous trajectory can be modulated arbitrarily by altering the initial amplitude and the nonlocal nonlinear coefficient. In addition, the initial amplitude and the nonlocal nonlinear coefficient can have inverse impacts on the formation and transformation of the equilibrium state of spatial solitons, when the two parameters are larger than certain values. Therefore, the reversible transformation of the evolution dynamics of two soliton states can be realized by adjusting those two parameters properly. Finally, it is shown that the propagation properties of the solitons formed by the interaction between Airy beam and nonlocal nonlinear medium can be controlled arbitrarily, by adjusting the distribution factor and nonlocal coefficient.