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- 검색키워드
- 저자 : Gao-Le Dai (검색결과 4 건)
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The Modeling Methods of Heavy NC Machine Tool Bolt Joint Based on Virtual Media
Ren Sheng-Le,Gao Fei,Dai Ye,Wang Peng,Cheng Tian-Yu 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.9
The Department of Heavy NC machine tool has a great influence on the performance of machine tools. The 30%-50% static stiffness, more than 50% of the dynamic stiffness depends on the combining part, and the influence on damping reached 90%.Machine tool with the Department of static and dynamic performance directly determines the accuracy and reliability of Heavy NC machine tool. Therefore, in conjunction with the Department of research and design of Heavy NC machine tool is very important. In this paper, based on Hertz contact theory, the contact at the micro level, considering the combination form of machine tool, and the machine joints as a virtual media simulation, a combination of virtual media framework, and calculation of characteristic parameters of the virtual material, then use the ANSYS Workbench to solve the combination of the natural frequency of the whole, the first five order modal extraction. Using modal test technology, get the specimens of natural frequency and damping of the true value, natural frequency are compared with theory, prove the formula of virtual media is reliable, can be used in the modeling of heavy machine tool.
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A Novel Unequal Broadband Out-of-Phase Power Divider Using DSPSLs
Yun Long Lu,Gao-Le Dai 한국전자통신연구원 2014 ETRI Journal Vol.36 No.1
In this paper, a novel unequal broadband out-of-phasepower divider (PD) is presented. Double-sided parallelstriplines (DSPSLs) are employed to achieve an out-ofphaseresponse. Also, an asymmetric dual-band matchingstructure with two external isolation resistors is utilized toobtain arbitrary unequal power division, in which theresistors are directly grounded for heat sinking. A throughground via (TGV), connecting the top and bottom sides ofthe DSPSLs, is used to short the isolation components. Additionally, this property can efficiently improve thebroadband matching and isolation bandwidths. Toinvestigate the proposed divider in detail, a set of designequations are derived based on the circuit theory andtransmission line theory. The theoretical analysis showsthat broadband responses can be obtained as properfrequency ratios are adopted. To verify the proposedconcept, a sample divider with a power division of 2:1 isdemonstrated. The measured results exhibit a broadbandwidth from 1.19 GHz to 2.19 GHz (59.2%) with areturn loss better than 10 dB and port isolation of 18 dB.
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Novel Filtering Power Divider with External Isolation Resistors
Yun Long Lu,Shun Wang,Gao-Le Dai,Kai Li 한국전자통신연구원 2015 ETRI Journal Vol.37 No.1
In this paper, a novel filtering power divider with external isolation resistors is presented. The proposed power divider can be considered as an integration of a bandpass filter and a Gysel power divider. Based on the circuit topology, a high-order filtering power divider can be easily realized. Odd- and even-mode models are employed to analyze the filtering and power splitting functions. For demonstration, a third-order filtering power divider operating at 1.5 GHz is designed and implemented. The measured results exhibit an isolation between the output ports that is better than 20 dB at around the center frequency.
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Jiangtao Su,Na Lin,Xiangyu You,Heshuang Dai,Meng Rao,Lu Ye,Fan Ye,Le Cai,Yuxin Chen,Gao Zhou,Xiaoxia Guo 한국고분자학회 2023 Macromolecular Research Vol.31 No.11
Systemic toxicity, poor aqueous solubility, and poorly cell permeable ability hindered the clinical application of Celastrol. In this study, we aimed to design and synthesize an amphiphilic conjugate to encapsulate Celastrol into micelles to improve its water solubility, cellular membrane penetration, improving the clinic translation potential of Celastrol for the treatment of psoriasis. For this purpose, we first synthesized gelatin and oleic acid conjugate (GOC-1), and then covalently bonded 4-(3-boronophenylamino)-4-oxobutanoic acid (BPOA) with GOC-1 to form a stable GOC-2 conjugate which can self-assemble into micelles in aqueous solution. Celastrol (Cel) was physically encapsulated into the core of GOCs micelles. The dynamic stability, particle size, drug release, zeta potential, drug-loading efficiency, and surface morphology of Cel/loaded GOCs nano-micelles were determined. In addition, cell viability, cellular uptake of Cel/loaded GOC-2, and skin permeation and in vivo anti-psoriasis effect of Cel-loaded GOC-2 were investigated. Our results have shown that Cel/loaded GOC-1 and Cel/loaded GOC-2 have spherical shapes with diameters of around 200–300 nm. Compared to GOC-1, GOC-2 micelles showed higher drug-loading efficiency and excellent permeation ability in vitro. Moreover, Cel/GOC-2 micelles reduced erythema and white scales on the dorsal skin of psoriatic mice. In conclusion, BPOA attached GOC nanoparticles as a Celastrol carrier not only increase its water solubility but also improve drug-loading efficiency and cell permeation ability, exhibiting superior anti-psoriatic effect than the commercially available tacrolimus. Our work is expected to provide a facile approach to prepare nanocarrier for Celastrol to improve the clinic translation potential of Celastrol.
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