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      • KCI등재

        Magnetism and Thermodynamic Properties of a Spin-1/2 Ferrimagnetic Diamond XY Chain in Magnetic Fields at Finite Temperatures

        Tai-Min Cheng,Yan-Ming Ma,Chong-Yuan Ge,Shu-Sheng Sun,Wei-Ye Jia,Qing-Yun Li,Xiao-Fei Shi,Lin Li,Lin Zhu 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.1

        The elementary excitation spectra of a one-dimensional ferrimagnetic diamond chain in the spin- 1/2 XY model at low temperatures have been calculated by using an invariant eigen-operator (IEO) method, the energies of elementary excitations in different specific cases are discussed, and the analytic solutions of three critical magnetic field intensities (<i>H</i><sub>C1</sub>, <i>H</i><sub>C2</sub>, and <i>H</i><sub>peak</sub>) are given. The magnetization versus external magnetic field curve displays a 1/3 magnetization plateau at low temperatures, in which <i>H</i><sub>C1</sub> is the critical magnetic field intensity from the disappearance of the 1/3 magnetization plateau to spin-flop states, <i>H</i><sub>C2</sub> is the critical magnetic field intensity from spin-flop states to the saturation magnetization, and Hpeak is the critical magnetic field intensity when the temperature magnetization shows a peak in the external magnetic field. The temperature dependences of the magnetic susceptibility and the specific heat show a double peak structure. The entropy and the magnetic susceptibility versus external magnetic field curves also exhibit a double peak structure, and the positions of the two peaks correspond to <i>H</i><sub>C1</sub> and <i>H</i><sub>C2</sub>, respectively. This derives from the competition among different types of energies: the temperature-dependent thermal disorder energy, the potential energy of the spin magnetic moment, the ferromagnetic exchange interaction energy, and the anti-ferromagnetic exchange interaction energy. However at low temperatures, the specific heat as a function of external magnetic field curve exhibits minima at the above two critical points (<i>H</i><sub>C1</sub> and <i>H</i><sub>C2<sub>). The origins of the above phenomena are discussed in detail.

      • KCI등재

        Two New Acorane Sesquiterpenes from Illicium henryi

        Tai-Fa Song,Wei-Dong Zhang,Xin-Hua Xia,Yun-Heng Shen,Chun-Mei Liu,Sheng Lin,Hui-zi Jin,Hui-Liang Li 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.9

        Two new acorane sesquiterpenes, 10-hydroxyacoronene (1) and 1β-isopropyl-4β-methyl-9β-hydroxy spiro[4.5]dec-6-en-8-one (2), one new natural product, 4-hydroxy-4, 6-dimethyl-1-tetralone (3), and one known acorane sesquiterpene, acoradiepoxide (4) were isolated from the twigs and leaves of Illicium henryi. The structures of the new compounds were elucidated primarily on the basis of analysis of spectroscopic data. In addition, the inhibitory effect on NO production of these compounds were tested. Compounds 1 and 4 exhibited slight inhibitory effects on NO production with IC50 values of 82.4 μg/mL and 76.5 μg/mL, respectively.

      • Sensorless Assistive Torque Design for a Lower Extremity Exoskeleton

        Kai-Tai Song,Yun-Chih Liao,You-Lin Jian 제어로봇시스템학회 2014 제어로봇시스템학회 국제학술대회 논문집 Vol.2014 No.10

        For improving mobility of the elderly, it is desirable to use a lower limb exoskeleton to enhance strength and endurance for their daily life activities. This paper presents a novel design of assist torque generation and compliant motion of a knee joint for an exoskeleton robot. Based on a sensorless approach, a method is suggested to estimate the external torque and generate the assistance torque of the attached DC motor. The developed lower limb exoskeleton joint provides assistive torque in order to comply with motion of the user. In comparison with existing lower limb exoskeletons, the proposed exoskeleton robot can execute various training programs by adjusting the assisting torque with less sensors and reduced hardware complexity. Experimental results on a knee exoskeleton validate the proposed method. Desirable assistive torque can be generated to be compliant with a swing motion.

      • KCI등재

        Risks of cervical intraepithelial neoplasia grade 3 or invasive cancers in ASCUS women with different management: a population-based cohort study

        Yi-Jou Tai,Yun-Yuan Chen,Huang-Cheng Hsu,Chun-Ju Chiang,San-Lin You,Chi-An Chen,Wen-Fang Cheng,Taiwan Cervical Cancer Control Task Force 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.4

        OBJECTIVE: To investigate the progression risk of atypical squamous cells of undetermined significance (ASCUS) with different clinical managements. METHODS: Women with their first diagnosis of ASCUS cytology were retrieved from the national cervical cancer screening database and linked to the national health insurance research database to identify the management of these women. The incidences of developing cervical intraepithelial neoplasia grade 3 and invasive cervical cancer (CIN3+) were calculated, and the hazard ratios (HRs) were estimated using a Cox proportional hazards model. This study was approved by the Research Ethics Committee of the National Taiwan University Hospital and is registered at ClinicalTrials.gov (Identifier: NCT02063152). RESULTS: There were total 69,741 women included. Various management strategies including colposcopy, cervical biopsies and/or endocervical curettage, and cryotherapy, failed to reduce the risk of subsequent CIN3+ compared with repeat cervical smears. Loop electrosurgical excision procedure/conization significantly decreased risk of subsequent CIN3+ lesions (HR=0.22; 95% confidence interval [CI]=0.07–0.68; p=0.010). Women in their 40s–50s had an approximately 30% risk reduction compared to other age groups. Women with a previous screening history >5 years from the present ASCUS diagnosis were at increased risk for CIN3+ (HR=1.24; 95% CI=1.03–1.49; p=0.020). CONCLUSION: In women of first-time ASCUS cytology, a program of repeat cytology can be an acceptable clinical option in low-resource settings. Caution should be taken especially in women with remote cervical screening history more than 5 years.

      • SCIESCOPUSKCI등재

        Effects of Saccharomyces cerevisiae and phytase co-fermentation of wheat bran on growth, antioxidation, immunity and intestinal morphology in broilers

        Chuang, Wen-Yang,Lin, Li-Jen,Hsieh, Yun-Chen,Chang, Shen-Chang,Lee, Tzu-Tai Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.7

        Objective: The aim of this study was to investigate the effects of different amounts of wheat bran (WB) inclusion and postbiotics form by Saccharomyces cerevisiae and phytase co-fermented wheat bran (FWB) on the growth performance and health status of broilers. Methods: Study randomly allocated a total of 300 male broilers to a control and 4 treatment groups (5% WB, 5% FWB, 10% WB, and 10% FWB inclusion, respectively) with each pen having 20 broilers and 3 pens per treatment. Results: The WB does not contain enzymes, but there are 152.8, 549.2, 289.5, and 147.1 U/g dry matter xylanase, protease, cellulase and β-glucanase in FWB, respectively. Furthermore, FWB can decrease nitric oxide release of lipopolysaccharide stimulated chicken peripheral blood mononuclear cells by about two times. Results show that 10% FWB inclusion had significantly the highest weight gain (WG) at 1 to 21 d; 5% FWB had the lowest feed conversion rate at 22 to 35 d; 10% WB and 10% FWB inclusion have the highest villus height and Lactobacillus spp. number in caecum; and both 5% and 10% FWB can increase ash content in femurs. Compared to control group, all treatments increase mucin 2, and tight junction (TJ), such as occludin, claudin-1, zonula occludens-1, and mRNA expression in ileum by at least 5 folds. In chicken peripheral blood mononuclear cells, nicotinamide adenine dinucleotide phosphate-oxidase-1 mRNA expression decreases from 2 to 5 times, and glutamate-cysteine ligase catalytic subunit mRNA expression also increases in all treatment groups compared to control group. The mRNA expression of pro-inflammatory cytokines, including interleukin-6 (IL-6), nuclear factor-κB, and IL-1β, decreases in 5% and 10% FWB groups compared to control group. Conclusion: To summarize, both WB and FWB inclusion in broilers diets increase TJ mRNA expression and anti-oxidation and anti-inflammation, but up to 10% FWB groups have better WG in different stages of broiler development.

      • KCI등재

        Effect of patient decision aids on choice between sugammadex and neostigmine in surgeries under general anesthesia: a multicenter randomized controlled trial

        Wang Li-Kai,Lin Yao-Tsung,Chen Jui-Tai,Lan Winnie,Hung Kuo-Chuan,Chen Jen-Yin,Liu Kuei-Jung,Yen Yu-Chun,Chou Yun-Yun,Cherng Yih-Giun,Tam Ka-Wai 대한마취통증의학회 2023 Korean Journal of Anesthesiology Vol.76 No.4

        Background: Shared decision making using patient decision aids (PtDAs) was established over a decade ago, but few studies have evaluated its efficacy in Asian countries. We therefore evaluated the application of PtDAs in a decision conflict between two muscle relaxant reversal agents, neostigmine and sugammadex, and sequentially analyzed the regional differences and operating room turnover rates.Methods: This multicenter, outcome-assessor-blind, randomized controlled trial included 3,132 surgical patients from two medical centers admitted between March 2020 and August 2020. The patients were randomly divided into the classical and PtDA groups for pre-anesthesia consultations. Their clinicodemographic characteristics were analyzed to identify variables influencing the choice of reversal agent. On the day of the pre-anesthesia consultation, the patients completed the four SURE scale (sure of myself, understand information, risk-benefit ratio, encouragement) screening items. The operating turnover rates were also evaluated using anesthesia records. Results: Compared with the classical group, the PtDA group felt more confident about receiving sufficient medical information (P < 0.001), felt better informed about the advantages and disadvantages of the medications (P < 0.001), exhibited a superior understanding of the benefits and risks of their options (P < 0.001), and felt surer about their choice (P < 0.001). Moreover, the PtDA group had a significantly greater tendency to choose sugammadex over neostigmine (P < 0.001). Conclusions: PtDA interventions in pre-anesthesia consultations provided surgical patients with clear knowledge and better support. PtDAs should be made available in other medical fields to enhance shared clinical decision-making.

      • Recombinant adenylate kinase 3 from liver fluke <i>Clonorchis sinensis</i> for histochemical analysis and serodiagnosis of clonorchiasis

        Kwon, Soon Bin,Kim, Paul,Woo, Hae Sun,Kim, Tae Yun,Kim, Ju Yeong,Lee, Hye Min,Jang, Yun Soo,Kim, Eun-Min,Yong, Tai-Soon,Seong, Baik Lin Cambridge University Press 2018 Parasitology Vol.145 No.12

        <B>Abstract</B><P>Due to the lack of an effective prophylactic intervention and diagnosis, human liver fluke <I>Clonorchis sinensis</I> continues to afflict a large human population, causing a chronic inflammatory bile duct disease. With an aim to identify target antigens for sensitive serodiagnosis, adenylate kinase 3 of <I>C. sinensis</I> (CsAK3) was successfully expressed in soluble form in <I>Escherichia coli</I> by fusion to an RNA-interacting domain derived from human Lys-tRNA synthetase and purified by Ni<SUP>2+</SUP>-affinity chromatography. Anti-CsAK3 serum was raised by immunization of mice, and Western blotting confirmed that CsAK3 was expressed in adult-stage <I>C. sinensis</I>. Histochemical analysis showed that CsAK3 was localized to the subtegumental tissue of <I>C. sinensis</I> and was excreted into the bile duct of the host. When tested against sera from various parasite-infected patients by enzyme-linked immunosorbent assay, the recombinant CsAK3 elicited a specific response to <I>C. sinensis</I>-infected sera. The results suggest that CsAK3, either alone or in combination with other antigens, could be used for improving the clinical diagnosis of clonorchiasis.</P>

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