Research on Li0.3Na0.18K0.52NO3 promoted Mg20Al-CO3 LDH/GO composites for CO2 capture

Ying Yang,Kai Chen,Liang Huang,Min Li,Taiping Zhang,Mi Zhong,Ping Ning,Junya Wang,Shikun Wen 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.102 No.-

It has been reported that the addition of graphene oxide (GO) can increase the dispersion and heterogeneousnucleation of layered double hydroxide (LDH), thus providing more active sites, which is more conduciveto CO2 adsorption. Herein, we reported alkali metal nitrates ((Li0.3Na0.18K0.52)NO3) promoted LDHand GO composites (LDH/GO) as adsorbents for CO2 capture. The influence of mass ratio of LDH to GO, theimpregnation ratio of alkali metal nitrates, the calcination and adsorption temperature, as well as thecycling stability were investigated systematically. The results indicated that the CO2 capture capacityof LDH/GO composite with 30 mol% (Li0.3Na0.18K0.52)NO3 could reach 4.51 mmol g 1, which was 5.86times higher than LDH/GO1 without loading alkali metal nitrates. Moreover, it had outstanding CO2adsorption capacity in the range from 200 C to 320 C. In addition, the cyclic adsorption and desorptiontest manifested that the CO2 uptake of the material can reach 3.07 mmol g 1 after 22 cycles. We believethat this study will give a significant contribution to fabrication of LDH based composites as CO2 adsorbentsin future study.

Realizing highly efficient multicolor tunable emissions from Tb³⁺ and Eu³⁺ co-doped CaGd₂(WO₄)₄ phosphors via energy transfer by single ultraviolet excitation for lighting and display applications

Huang, Xiaoyong,Li, Bin,Du, Peng,Guo, Heng,Cao, Renping,Yu, Jae Su,Wang, Kai,Sun, Xiao Wei Elsevier 2018 Dyes and pigments Vol.151 No.-

<P><B>Abstract</B></P> <P>In this paper, we reported on multicolor emission tuning in Tb<SUP>3+</SUP> and Eu<SUP>3+</SUP> co-doped CaGd<SUB>2</SUB>(WO<SUB>4</SUB>)<SUB>4</SUB> phosphors prepared by a traditional high-temperature solid-state reaction. Upon 380 nm ultraviolet excitation, the emission color of CaGd<SUB>2</SUB>(WO<SUB>4</SUB>)<SUB>4</SUB>:Tb<SUP>3+</SUP>,Eu<SUP>3+</SUP> phosphors can be readily tuned from green to yellow, orange and finally to pure red through varying the concentration ratio of Eu<SUP>3+</SUP> and Tb<SUP>3+</SUP> ions. The energy transfer mechanism from Tb<SUP>3+</SUP> to Eu<SUP>3+</SUP> was systematically investigated by photoluminescence spectra, luminescence decay times, and time-resolved spectra. The internal quantum efficiencies of these phosphors were measured, and their thermal stability was also studied. A prototype white light-emitting diode (LED) device was fabricated by using an ultraviolet chip combined with a blend of blue-emitting BaMgAl<SUB>10</SUB>O<SUB>l7</SUB>:Eu<SUP>2+</SUP> phosphors, green-emitting BaSrSiO<SUB>4</SUB>:Eu<SUP>2+</SUP> phosphors, and red-emitting CaGd<SUB>2</SUB>(WO<SUB>4</SUB>)<SUB>4</SUB>:50%Tb<SUP>3+</SUP>,50%Eu<SUP>3+</SUP> phosphors. All the results indicate that the CaGd<SUB>2</SUB>(WO<SUB>4</SUB>)<SUB>4</SUB>:Tb<SUP>3+</SUP>,Eu<SUP>3+</SUP> has great potential application in lighting and displays.</P> <P><B>Highlights</B></P> <P> <UL> <LI> CaGd<SUB>2</SUB>(WO<SUB>4</SUB>)<SUB>4</SUB>:Tb<SUP>3+</SUP>,Eu<SUP>3+</SUP> showed efficient energy-transfer from Tb<SUP>3+</SUP> to Eu<SUP>3+</SUP>. </LI> <LI> CaGd<SUB>2</SUB>(WO<SUB>4</SUB>)<SUB>4</SUB>:Tb<SUP>3+</SUP>,Eu<SUP>3+</SUP> exhibited tunable color emission under 380 nm excitation. </LI> <LI> The energy-transfer mechanism was studied in detail. </LI> <LI> Quantum efficiency and thermal stability were investigated. </LI> <LI> The proof-of-concept LED lamps were fabricated by employing phosphors and UV LEDs. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Activation of formyl CH and hydroxyl OH bonds in HMF by the CuO(1 1 1) and Co₃O₄(1 1 0) surfaces: A DFT study

Ren, Jun,Song, Kai-he,Li, Zhenhuan,Wang, Qiang,Li, Jun,Wang, Yingxiong,Li, Debao,Kim, Chan Kyung Elsevier 2018 APPLIED SURFACE SCIENCE - Vol.456 No.-

<P><B>Abstract</B></P> <P>The first principle calculations with on-site Coulomb repulsion U terms were carried out to investigate the 5-hydroxymethylfurfural (HMF) adsorption on the CuO(1 1 1) and Co<SUB>3</SUB>O<SUB>4</SUB>(1 1 0) surfaces, two widely used oxidation catalysts. The adsorption of HMF molecule is energetically favoured in both cases, and HMF is more inclined to bridge adsorption via hydroxyl and formyl groups binding with surface O and metal sites. Moreover, the adsorption energy relies on both the coordination type of surface lattice oxygen to which the H atom binds and the formation of H-bond involving hydroxyl and formyl groups on the adsorbed HMF. Also, the hydroxyl OH bond breaking is very easy and is likely to be the first step in HMF oxidation, and then the OH insertion reaction to produce 2,5-furandicarboxylic acid (FDCA). The corresponding experimental results also show that the CuO and Co<SUB>3</SUB>O<SUB>4</SUB> surfaces are promising candidate catalysts.</P> <P><B>Highlights</B></P> <P> <UL> <LI> CuO(1 1 1) and Co<SUB>3</SUB>O<SUB>4</SUB>(1 1 0) surfaces catalyze the oxidation of 5-hydroxymethylfurfural (HMF). </LI> <LI> Initial binding was formed through bridged-adsorption with O atoms in HMF. </LI> <LI> Oxidation reaction proceeds through the OH bond breaking pathway. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Schematic potential energy diagram for the formyl CH and hydroxyl OH bonds of HMF dissociation on CuO(1 1 1) and Co<SUB>3</SUB>O<SUB>4</SUB>(1 1 0) surfaces. Obviously, the hydroxyl OH bond breaking is easier than that of the formyl CH bond on the two surfaces, which indicates the first step of oxidation of HMF to FDCA should be hydroxyl OH bond breaking.</P> <P>[DISPLAY OMISSION]</P>

Trichoderma biodiversity in major ecological systems of China

Kai Dou,Jinxin Gao,Chulong Zhang,Hetong Yang,Xiliang Jiang,Jishun Li,Yaqian Li,Wei Wang,Hongquan Xian,Shigui Li,Yan Liu,Jindong Hu,Jie Chen 한국미생물학회 2019 The journal of microbiology Vol.57 No.8

An investigation of Trichoderma biodiversity involving a large-scale environmental gradient was conducted to understand the Trichoderma distribution in China. A total of 3,999 isolates were isolated from forestry, grassland, wetland and agriculture ecosystems, and 50 species were identified based on morphological characteristics and sequence analysis of genetic markers. Trichoderma harzianum showed the largest proportion of isolates and the most extensive distribution. Hypocrea semiorbis, T. epimyces, T. konilangbra, T. piluliferum, T. pleurotum, T. pubescens, T. strictipilis, T. hunua, T. oblongisporum and an unidentified species, Trichoderma sp. MA 3642, were first reported in China. Most Trichoderma species were distributed in Jilin and Heilongjiang Provinces in northeast China and the fewest were distributed in Qinghai Province. Based on the division of ecological and geographic factors, forestry ecosystems and low-altitude regions have the greatest species biodiversity of Trichoderma.

Prognostic Value of MGMT Promoter Methylation and TP53 Mutation in Glioblastomas Depends on IDH1 Mutation

Wang, Kai,Wang, Yin-Yan,Ma, Jun,Wang, Jiang-Fei,Li, Shao-Wu,Jiang, Tao,Dai, Jian-Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

Several molecular markers have been proposed as predictors of outcome in patients with glioblastomas. We investigated the prognostic significance of $O^6$-methylguanine-DNA methyltransferase (MGMT) promoter methylation and TP53 mutation status dependent on isocitrate dehydrogenase 1 (IDH1) mutation in glioblastoma patients. A cohort of 78 patients with histologically confirmed glioblastomas treated with radiation therapy and chemotherapy were reviewed retrospectively. We evaluated the prognostic value of MGMT promoter methylation and TP53 mutation status with regard to progression-free survival (PFS) and overall survival (OS). It was revealed that mutations in IDH1, promoter methylation of MGMT, TP53 mutation, age, Karnofsky performance status (KFS), and extension of resection were independent prognostic factors. In patients with an IDH1 mutation, those with an MGMT methylation were associated with longer PFS (p=0.016) and OS (p=0.013). Nevertheless, the presence of TP53 mutation could stratify the PFS and OS of patients with IDH1 wild type (p=0.003 and 0.029 respectively, log-rank). The MGMT promoter methylation and TP53 mutation were associated with a favorable outcome of patients with and without mutant IDH1, respectively. The results indicate that glioblastomas with MGMT methylation or TP53 mutations have improved survival that may be influenced by IDH1 mutation status.

Clinical Application of Transcatheter Arterial Chemoembolization Combined with Synchronous C-arm Cone-Beam CT Guided Radiofrequency Ablation in treatment of Large Hepatocellular Carcinoma

Wang, Zhi-Jun,Wang, Mao-Qiang,Duan, Feng,Song, Peng,Liu, Feng-Yong,Wang, Yan,Yan, Jie-Yu,Li, Kai,Yuan, Kai Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Objective: This work aimed to evaluate the safety and clinical efficacy of transcatheter arterial chemoembolization (TACE) combined with c-arm cone-beam CT guided synchronous radiofrequency ablation (RFA) in treatment of large hepatocellular carcinoma (HCC). Methods: 21 patients with large HCC were studied from January 2010 to March 2012. TACE combined with synchronous C-arm cone-beam CT guided RFA were performed on a total of 25 lesions. Conventional imaging examination (CEUS, enhanced CT or MRI) and AFP detection were regularly conducted to evaluate the technical success rate of combined treatment, complications, treatment response, time without disease recurrence and survival rate. Results: The technical success rate of combined treatment was 100%, without any significant complication. After 1 month, there were 19 cases with complete response and 2 cases with partial response, with an complete response rate of 90.4% (19/21) and a clinical effective rate of 100% (21/21). The complete response rates of single nodular lesions (100%, 17/17) was significantly higher than that of multiple nodular lesions (50%, 2/4) (P<0. 05). During 2 to 28 months of follow-up, in 19 cases with complete response, the average time without disease recurrence was $10.8{\pm}6$ months. The total survival rates of 6, 12 and 18 months in 21 patients were 100%, respectively. Conclusion: TACE combined with synchronous C-arm CT guided RFA is safe and effective for treatment of large HCC. The treatment efficacy for single nodular lesion is better than that for multiple nodular lesions.

miR-379 Inhibits Cell Proliferation, Invasion, and Migration of Vascular Smooth Muscle Cells by Targeting Insulin-Like Factor-1

Kai Li,Yong Wang,Anji Zhang,Baixue Liu,Li Jia 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.1

Purpose: MicroRNAs are small non-coding RNAs that play important roles in vascular smooth muscle cell (VSMC) function. Thisstudy investigated the role of miR-379 on proliferation, invasion, and migration of VSMCs and explored underlying mechanismsthereof. Materials and Methods: MicroRNA, mRNA, and protein levels were determined by quantitative real-time PCR and western blot. The proliferative, invasive, and migratory abilities of VSMCs were measured by CCK-8, invasion, and wound healing assay, respectively. Luciferase reporter assay was used to confirm the target of miR-379. Results: Platelet-derived growth factor-bb was found to promote cell proliferation and suppress miR-379 expression in VSMCs. Functional assays demonstrated that miR-379 inhibited cell proliferation, cell invasion, and migration. Flow cytometry results furthershowed that miR-379 induced apoptosis in VSMCs. TargetScan analysis and luciferase report assay confirmed that insulin-likegrowth factor-1 (IGF-1) 3’UTR is a direct target of miR-379, and mRNA and protein levels of miR-379 and IGF-1 were inversely correlated. Rescue experiments showed that enforced expression of IGF-1 sufficiently overcomes the inhibitory effect of miR-379 on cellproliferation, invasion, and migration in VSMCs. Conclusion: Our results suggest that miR-379 plays an important role in regulating VSMCs proliferation, invasion, and migrationby targeting IGF-1.

Kojic Acid Protects C57BL/6 Mice from Gamma-irradiation Induced Damage

Wang, Kai,Liu, Chao,Di, Chan-Juan,Ma, Cong,Han, Chun-Guang,Yuan, Mei-Ru,Li, Peng-Fei,Li, Lu,Liu, Yong-Xue Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1

The radioprotective effects of a single administration of kojic acid (KA) against ionizing radiation were evaluated via assessment of 30-day survival and alterations of peripheral blood parameters of adult C57BL/6 male mice. The 30-day survival rate of mice pretreated with KA (75 or 300 mg/kg body weight, KA75 or KA300) subcutaneously 27 h prior to a lethal dose (8 Gy, 153.52 cGy/min) of gamma irradiation was higher than that of mice irradiated alone (40% or 60% vs 0%). It was observed that the white blood cell (WBC) count/the red blood cell (RBC) count, haemoglobin content, haematocrit and platelet count of mice with or without KA pretreatment as exposed to a sub-lethal dose (4 Gy, 148.14 cGy/min) of gamma irradiation decreased maximally at day 4/day 8 post-irradiation. Although the initial WBC values were low in KA300 or WR-2721 (amifostine) groups, they significantly recovered to normal at day 19, whereas in the control group they did not. The results from the cytotoxicity and cell viability assays demonstrated that KA could highly protect Chinese hamster ovary (CHO) cells against ionizing radiation with low toxicity. In summary, KA provides marked radioprotective effects both in vivo and in vitro.

Evaluation of the gastroprotective effects of 20 (S)-ginsenoside Rg3 on gastric ulcer models in mice

Kai Zhang,Ying Liu,Cuizhu Wang,Jiannan Li,Lingxin Xiong,Zhenzhou Wang,Jinping Liu,Pingya Li 고려인삼학회 2019 Journal of Ginseng Research Vol.43 No.4

Background: Gastric ulcer (GU) is a common gastrointestinal disease that can be induced by many factors. Finding an effective treatment method that contains fewer side effects is important. 20 (S)-ginsenosideRg3 is a kind of protopanaxadiol and has shown superior antiinflammatory and antioxidanteffects in many studies, especially cancer studies. In this study, we examined the treatment efficacy of 20(S)-ginsenoside Rg3 on GU. Methods: Three kinds of GU models, including an alcohol GU model, a pylorus-ligated GU model, and anacetic acid GU model, were used. Mouse endothelin-1 (ET-1) and nitric oxide (NO) levels in blood andepidermal growth factor (EGF), superoxide dismutase, and NO levels in gastric mucosa were evaluated. Hematoxylin and eosin staining of gastric mucosa and immunohistochemical staining of ET-1, induciblenitric oxide synthase (NOS2), and epidermal growth factor receptors were studied. Ulcer index (UI)scores and UI ratios were also analyzed to demonstrate the GU conditions in different groups. Furthermore,Glide XP from Schrödinger was used for molecular docking to clarify the interactions between 20(S)-ginsenoside Rg3 and EGF and NOS2. Results: 20 (S)-ginsenoside Rg3 significantly decreased the UI scores and UI ratios in all the three GUmodels, and it demonstrated antiulcer effects by decreasing the ET-1 and NOS2 levels and increasing theNO, superoxide dismutase, EGF, and epidermal growth factor receptor levels. In addition, high-dose 20(S)-ginsenoside Rg3 showed satisfactory gastric mucosa protection effects. Conclusion: 20 (S)-ginsenoside Rg3 can inhibit the formation of GU and may be a potential therapeuticagent for GU.

Preliminary Application of High-Definition CT Gemstone Spectral Imaging in Hand and Foot Tendons

Kai Deng,Cheng-Qi Zhang,Wei Li,Jun-Jun Wang,Xin-Yi Wang,Tao Pang,Guang-Li Wang,Cheng Liu 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.6

Objective: To assess the feasibility of visualizing hand and foot tendon anatomy and disorders by Gemstone Spectral Imaging (GSI) high-definition CT (HDCT). Materials and Methods: Thirty-five patients who suffered from hand or foot pain were scanned with GSI mode HDCT and MRI. Spectrum analysis was used to select the monochromatic images that provide the optimal contrast-to-noise ratio (CNR) for tendons. The image quality at the best selected monochromatic level and the conventional polychromatic images were compared. Tendon anatomy and disease were also analyzed at GSI and MRI. Results: The monochromatic images at about 65 keV (mean 65.09 ± 2.98) provided the optimal CNR for hand and foot tendons. The image quality at the optimal selected monochromatic level was superior to conventional polychromatic images (p = 0.005, p < 0.05). GSI was useful in visualizing hand and foot tendon anatomy and disorders. There were no statistical differences between GSI and MRI with regard to tendon thickening (χ2 = 0, p > 0.05), compression (χ2 = 0.5, p > 0.05), absence (χ2 = 0, p > 0.05) and rupture (χ2 = 0, p > 0.05). GSI was significantly less sensitive than MRI in displaying tendon adhesion (χ2 = 4.17, p < 0.05), degeneration (χ2 = 4.17, p < 0.05), and tendinous sheath disease (χ2 = 10.08, p < 0.05). Conclusion: GSI with monochromatic images at 65 keV displays clearly the most hand and foot tendon anatomy and disorders with image quality improved, as compared with conventional polychromatic images. It may be used solely or combined with MRI in clinical work, depending on individual patient disease condition. Objective: To assess the feasibility of visualizing hand and foot tendon anatomy and disorders by Gemstone Spectral Imaging (GSI) high-definition CT (HDCT). Materials and Methods: Thirty-five patients who suffered from hand or foot pain were scanned with GSI mode HDCT and MRI. Spectrum analysis was used to select the monochromatic images that provide the optimal contrast-to-noise ratio (CNR) for tendons. The image quality at the best selected monochromatic level and the conventional polychromatic images were compared. Tendon anatomy and disease were also analyzed at GSI and MRI. Results: The monochromatic images at about 65 keV (mean 65.09 ± 2.98) provided the optimal CNR for hand and foot tendons. The image quality at the optimal selected monochromatic level was superior to conventional polychromatic images (p = 0.005, p < 0.05). GSI was useful in visualizing hand and foot tendon anatomy and disorders. There were no statistical differences between GSI and MRI with regard to tendon thickening (χ2 = 0, p > 0.05), compression (χ2 = 0.5, p > 0.05), absence (χ2 = 0, p > 0.05) and rupture (χ2 = 0, p > 0.05). GSI was significantly less sensitive than MRI in displaying tendon adhesion (χ2 = 4.17, p < 0.05), degeneration (χ2 = 4.17, p < 0.05), and tendinous sheath disease (χ2 = 10.08, p < 0.05). Conclusion: GSI with monochromatic images at 65 keV displays clearly the most hand and foot tendon anatomy and disorders with image quality improved, as compared with conventional polychromatic images. It may be used solely or combined with MRI in clinical work, depending on individual patient disease condition.