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Li-Yun Lin,Chi-Yun Huang,Kuan-Chou Chen,Robert Y. Peng 한국원예학회 2021 Horticulture, Environment, and Biotechnology Vol.62 No.3
Grapefruit (G) parts contain abundant phenolic acids and fl avonoids (PPNs and FLVs). The wastes created from exocarps,mesocarps (G wastes, GW) and waste blanching water (WBW) lead to a considerable loss of PPNs and FLVs. Here, weassessed Buntan (CB), Buntan Hayata (CBH), and Peiyu (CP) cultivars and observed considerable amounts of PPNs andFLVs. The ethanolic extracts of GW (GWE) and WBW contained gallic acid, protocatechuic acid, chlorogenic acid, caff eicacid, ferulic acid, coumaric acid, naringin, hesperidin, diosmin, quercetin, hesperetin, nobiletin, and tangeretin (GWC). GWEhas previously been reported to be a relatively active antioxidant, anti-infl ammatory (based on the expression of TNF-αin Raw264.7 cells), antihypertensive, and anti-hyperglycemic compound. The IC 50 values for antihyperglycemic activitywith WBW for α-amylase were as follows: CB (27.96 ± 0.03 mg/mL) < CP (28.13 ± 0.19 mg/mL) < CBH (41.60 ± 0.16 mg/mL), and those for α-glucosidase were CB (1.80 ± 0.03 mg/mL) < CP (2.97 ± 0.29 mg/mL) < CBH (9.10 ± 0.51 mg/mL). GWC upregulated Glut4 in HepG2 cells, as well as the insulin secretion capability, and intracellular levels in RIN-m5Fcells, and it downregulated DPP4 in HepG2 cells. The IC 50 values for the angiotensin-converting enzyme activity were:CBP (5.10 ± 0.02 mg/mL) < CB (7.24 ± 0.65 mg/mL) < CP (8.60 ± 2.03 mg/mL). Our results indicate that PPNs and FLVspresent in GW are worth reclaiming.
Go, Yun Young,Rajapakse, R. P. V. Jayanthe,Kularatne, Senanayake A. M.,Lee, Pei-Yu Alison,Ku, Keun Bon,Nam, Sangwoo,Chou, Pin-Hsing,Tsai, Yun-Long,Liu, Yu-Lun,Chang, Hsiao-Fen Grace,Wang, Hwa-Tang Tho American Society for Microbiology 2016 Journal of clinical microbiology Vol.54 No.6
<P>Dengue virus (DENV) infection is considered a major public health problem in developing tropical countries where the virus is endemic and continues to cause major disease outbreaks every year. Here, we describe the development of a novel, inexpensive, and user-friendly diagnostic assay based on a reverse transcription-insulated isothermal PCR (RT-iiPCR) method for the detection of all four serotypes of DENV in clinical samples. The diagnostic performance of the newly established pan-DENV RT-iiPCR assay targeting a conserved 3' untranslated region of the viral genome was evaluated. The limit of detection with a 95% confidence was estimated to be 10 copies of in vitro-transcribed (IVT) RNA. Sensitivity analysis using RNA prepared from 10-fold serial dilutions of tissue culture fluid containing DENVs suggested that the RT-iiPCR assay was comparable to the multiplex real-time quantitative RT-PCR (qRT-PCR) assay for DENV-1, -3, and -4 detection but 10-fold less sensitive for DENV-2 detection. Subsequently, plasma collected from patients suspected of dengue virus infection (n = 220) and individuals not suspected of dengue virus infection (n = 45) were tested by the RT-iiPCR and compared to original test results using a DENV NS1 antigen rapid test and the qRT-PCR. The diagnostic agreement of the pan-DENV RT-iiPCR, NS1 antigen rapid test, and qRT-PCR tests was 93.9%, 84.5%, and 97.4%, respectively, compared to the composite reference results. This new RT-iiPCR assay along with the portable POCKIT nucleic acid analyzer could provide a highly reliable, sensitive, and specific point-of-need diagnostic assay for the diagnosis of DENV in clinics and hospitals in developing countries.</P>
YBa₂Cu₃O_(7-x) 세라믹과 YBa₂Cu₃O_(7-x)/Ag 복합체에서의 영率 對 氣空率의 상관관계
윤존도,초우예 경남대학교 신소재연구소 1995 論文集 Vol.5 No.-
YBa₂Cu₃O_(7-x) 초전도 세라믹 재료와 YBa₂Cu₃O_(7-x)/Ag 복합체의 명율에 미치는 기공율의 효과에 대하여 연구하였다. 서로 다른 기공율을 갖는 소결 시편의 영율을 상온에서 衝擊?? 起法(Impulse Excitation Technique)으로 측정하였다. 측정된 데이터를 영율과 기공율과의 상관관계에 대한 두 가지의 관계식-선형방정식과 스프리그스의 지수함수 방정식-과 비교함으로써 적합한 정량적 관계식을 구하고자 하였는데, 표준오차로 볼 때, 후자가 상대적으로 양호한 것으로 나타났다. 스프리그스의 관계식에 포함되어 있는 상수를 구해본 결과, 세라믹의 경우 3.7 복합체의 경우 3.84로 매우 근사한 것으로 밝혀져, 두 물질이 유사한 기공구조를 갖는다는 것을 보였다. 복합체의 영율은 세라믹의 그것보다 낮았는데, 이론적 영율의 상한과 하한과 비교함으로써 그 정량적 관계에 대한 이해가 시도되었다. The effect of porosity on the Young's modulus in YBa₂Cu₃O_{7-x} ceramics and YBa₂Cu₃O_{7-x}/25%Ag composites was studied. Young's moduli of the samples with various porosities were measured with the Impulse Excitation Technique. When the experimental data were fitted with the linear equation and the Spriggs exponential equation, both were found to be reasonably good with a little superioty in the latter, represented by the lower standard error. The b constant in the Spriggs equation was determined t o be 3 . 7 and 3.8 for the ceramics and the composites. respectively, implying the similarity of the pore structures of two different materials. The understanding of the effect of the addition of silver on a decrease in the Young's modulus was attempted by comparing the data with theoretical upper and lower bound of the modulus in the composites.
Yun-duk, Jeong,Yasu Watanabe,Khatereh Jamaat,Mohamed Sanad,Winston Chou,Melgie Franco 한국엔터테인먼트산업학회 2019 한국엔터테인먼트산업학회 학술대회 논문집 Vol.2019 No.11
The purpose of this study was to examine structural relationships between emotional experiences (joy and love), tourist satisfaction, and destination loyalty in the context of active sport tourism. Responses obtained from 201 participants were collected and analyzed. Results showed positive impacts of (a) joy, and love on tourist satisfaction, (b) joy and love on destination loyalty, and (c) tourist satisfaction on destination loyalty. Proceeding from this fact, one could logically assume that joy, love, and tourist satisfaction play key roles in predicting destination loyalty.
Chou Jui-Sheng,Chen Li-Ying,Liu Chi-Yun 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.1
Regulations mandate testing concrete’s compressive strength after the concrete has cured for 28 days. In the ideal situation, cured strength equals the target strength. Advanced estimation of concrete’s compressive strength can facilitate quality management, improve safety, and present economic advantages in sustainable use. Basic statistical methods cannot effectively predict concrete’s strength or its non-linear relationships with the proportions of its constituent materials. In this study, a baseline model for predicting concrete’s compressive strength was constructed using a state-of-the-art machine-learning method. Most related studies have used sets of concrete mix design results concerning concrete specimens for laboratory-produced concrete specimens as training sets and have obtained simple models through regression; however, these models have been unsuitable for onsite prediction of the compressive strength of concrete with the various mix designs. Control over mix proportions is high in laboratories, resulting in low variation; onsite manual operation and environmental factors cause significant variations in assessment data. In this study, machine-learning techniques and a newly developed metaheuristic optimization algorithm were applied to big long-term data from 75 concrete plants to construct the optimal machine-learning model. Our self-developed forensic-based investigation algorithm was employed to fine-tune the hyperparameters of the extreme gradient boosting model and to improve the model’s generalizability. The lowest mean absolute percentage error (MAPE) obtained using this model was 9.29%, which was smaller than the lowest MAPE achieved using the conventional simple regression with the water-to-binder (W/B) ratio (12.73%). The traditional method tends to overestimate the actual compressive strength. Finally, a convenient expert system was developed that facilitates the use of the proposed model by onsite engineers for quality management. This system expedites the judgment of whether a mixed design is reasonable, reducing production costs while maintaining the safety of concrete structures. It can be widely applied in practice and function as an effective decision-making tool.
A Cosmopolitan Approach to Transboundary Risk Governance in East Asia
Kuei Tien Chou,Yun Hsiang Lin,Jui Ning Chang 서울대학교 사회발전연구소 2022 Journal of Asian Sociology Vol.51 No.3
This paper points out that while genetically modified organisms (GMOs), bovine spongiform encephalopathy (BSE), and the Fukushima nuclear disaster that respectively occurred in the three East Asian countries of Taiwan, South Korea, and Japan, resulted in the emergence of compulsory cosmopolitanism, from the perspective of cross-border and transnational action. Although these countries all have full social movements domestically, a failure to develop connections between their organizations has resulted in these countries not yet seeing the emergence of cosmopolitan risk collectivities and a regional risk community. The authors explain that these countries have a common historical background of authoritarian politics, with all three possessing the structural factors of expert politics, scientific hegemony, and economic developmentalism. Such conditions formulate the hidden ignorance of risk and stagnates transformation. Therefore, not only are we yet to see any transnational connections between the NGOs in East Asia but there is also an emerging “hung risk governance.”