노인 인구에서 신경인지기능저하와 혈청 지질농도와의 상관성

유영선,최석주,정성수,김지은,윤성욱,전동욱,백준형,박성우,이정구,추일한,김영훈 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.6

Objectives : In this study, the authors evaluated the correlation between eurocognitive impairments and serum lipids levels among Korean elderly over the age of 65. Methods : A total of 609 elderly individuals participated in this study. Screening for cognitive impairments were carried out using the Mini-Mental Status Examination-Korean version (MMSE-KC). There were 197 subjects above 1.5SD Of MMSE- KC and they were evaluated using the Korean versions of the Consortium to Establish a Registry for Alzheimer's Disease (AD) (CERAD-KC) and Geriatric Depression Scale (GDS-K). Results : There was a correlation between old age/low levels of education and AD (p<0.05, P<0.01). There was an inverse correlation between the serum level of total cholesterol and the word list recognition test scores. The serum levels of LDL cholesterol were inversely correlated with the scores on the constructional praxis test, word list recall test and word list recognition test. Inverse correlations between the serum level of triglyceride and scores on the word list recall test and word list recognition test were also observed. Conclusion : There were inverse correlations between the serum levels of lipids and language/memory function in subjects with AD.

유리치은이식술의 임상증례

김유석,황규영,정승우 조선대학교 구강생물학연구소 2003 Oral Biology Research (Oral Biol Res) Vol.27 No.1

The free gingival graft has proven to be a predictable procedure for obtaining an increased width of attached gingiva, concomitantly increasing vestibular depth and eliminating the tension of an abnormal frenulum, and root coverage. The free gingival grafts is needed when the patient experiences discomfort during toothbrushing due to gingival recession and chewing due to an interfering lining mucosa and/or when the margin of restoration is placed in a subgingival position at sites with a thin gingiva that may favor an inflammatory tissue reaction in the presence of subgingival plaque. In this study, two patients were treated by the free gingiva1 grafts. One patient had no attached gingiva at lower left 2nd premolar, 2nd molar which were treated subgingival restoration and more inflammatory. The free gingival grafts were performed in this sites. The 1-2㎜ attached gingiva were obtained and maintained after 4monthes. The other had 3-4㎜ gingival recession at lower left 1st, 2nd premolar and experiences discomfort during toothbrushing, cold hypersensitivity. The free gingival grafts were performed in this sites. The 2-3㎜ root coverage were obtained and maintained after 30 months. The free gingival graft for increasing width and thickness of gingiva can be performed in case of subgingival restorations , gingival recession.

慢性 氣管支喘息 患者에 있어서의 N-(3',4'-dimethoxycinnamoyl) anthranilic acid의 臨床的 效果

康晳榮,金有瑩,文熙範 최신의학사 1985 最新醫學 Vol.28 No.1

저 발열량 페유 소각기 개발에 관한 실험적 연구

전영남,백원석,송형운,유경석,김성천 조선대학교 환경공해연구소 2004 環境公害硏究 Vol.18 No.-

The advanced waste oil incinerator is suggested that has heat recirculation region in the combustor to burn out the waste oil completely in high temperature zone and heat recuperator in the left side of combustion cavity which plays a role of the flame stabilization of main burner flame by heat recovery of exhaust gas to incinerate waste oil contained water. In order to investigate a simultaneously incineration efficiency of the vessel waste oil contained the hazardous waste which occurs from the vessel and the sea outflow waste oil experiments have been carried out using the emulsion fuel mixed the water and bunker fuel oil C and the blend mixed the light oil and the waste surrogate material (acetonitrile:CH_(3)CN). The results of experiments showed that the waste oil incinerator developed in this study was excellent for the incineration efficiency of waste oil at an air ratio of 1.46 and DRE (destruction and removal efficiencies) of CH_(3)CN was 99.9996% ("5 nines"). And optimum operating conditions for the secondary air flow rate of internal mix burner, preheating temperature and injection point of shipboard waste oil contained acetonitrile were suggested.

차체 점용접 접합부 피로강도의 실험해석

김정한,유희,염영진,주영우,주석재 울산대학교 1999 공학연구논문집 Vol.30 No.1

다양한 외부 동하중에 의한 피로파단이 발생하고 있는 승용차 차체 점용접 접합부에 대해 피로시험을 수행함으로써 전반적이 피로거동을 파악하고자 하였다. 실제 파단 발생 부재를 구성하는 차체재료중 SPCC, SPRC35, SAPH38P를 선택하여 용접조건, 동종 및 이종재료간의 접합, 두께 조합을 가급적 실차와 동일하게 적용하여 다양한 인장-전단 및 십자-인장 점용접 시편을 제작하였다. 그리고 정적시험 및 피로시험을 수행하여 강도 데이터베이스를 구축하였다. The fatigue behaviour of spot-welded joints of a car body, in which fatigue fracture occurs by various external dynamic loads, is characterized by performing fatigue tests. SPCC, SPRC35, and SAPH38P steels are selected which constitute the car body. Welding conditions and combinations of steels and thicknesses are chosen to reproduce those of a real car body and various tensile-shear and cross-tension spot-welded specimens are manufactured. Both static tests and fatigue tests are carried out, and the database of spot-weld strength is constructed.

흰쥐 척수 손상후 Parvalbumin과 Calbindin D-28K 함유신경세포에 관한 면역세포화학적 연구

김종중,정윤영,임유택,박상수,박영란,김현곤,문정석 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2

Background and Objectives: This study was done to compared the distribution of the two calcium-binding proteins immunoreactive neurons, parvalbumin immunoreactiv (PV-IR) and calbindin D-28K immunoreactive (CB-IR) neurons in the spinal cord after transection. Materials and Methods: Twenty rats were divided into 3 groups (control, complete spinal cord injury (SCI), and right and left spinal cord hemisection). SCI was produced by cutting the spinal cord use blades 11 with scalpel handles. Results: In this experiment, CB-IR neurons were mainly found in many pyramidal cells distributed in the brain stem and spinal cord of rats. PV-IR Neurons were demonstrated in all lamina of the gray matter of the spinal cord. These immunoreactive cells had the highest density in the layer I and II of dorsal horn and several nuclei of the ventral horn of the all the segments of the spinal cord. CB-IR neuropil labeling was strongly noted in all the segments of the spinal cord. In contrast PV-IR neurons were different in distribution, size and morphology in the spinal cord. The number of PV-IR neurons were greater than in the spinal cord compared with the CB-IR neurons. CB-IR and PV-IR somata were round, oval, spindle and polygonal in shape, and were unipolar, bipolar, multipolar and horizontal in types. The diameters of the somata of the PV-IR and CB-IR neurons were 40-50 ㎛, respectively. Also dendrites of PV-IR and CB-IR neurons were densely arrayed in network.

3-Joint Planar Type 로봇 매니퓰레이터의 자기동조적응제어에 관한 연구

김규로,양희주,유용석,최명진,오택열 慶熙大學校 大學院 院友會 1996 高凰論集 Vol.17 No.-

This study has parallelogram trajectory tracking of Three Joint Planar type Robot Manipulator. The equation of motion for the three joint planar manipulator are obtained by substituting Lagrange's energy expression into Euler-Lagrange's equation and forming the appropriate derivative. Lagrangian method allows us to obtain the dynamics equations for very complicated systems in the simplest manner possible. SISO model is used for design of the controller. The design of controllers may be considered primary controller for manipulators to track the desired trajectory under ideal conditions and secondary controller to compensates for undesirable deviations of the motion from the trajectory caused by external and internal disturbances. The aim of this paper is to evaluate the efficiency by self-tunning adaptive control and considering a characteristic of control. Through the computer simulation, obtained the following results 1) selt-tunning adaptive control is superior to PD control, 2) During the learning period, the adaptive control algorithm is searching proper estimates and controller gains. After this period, the outputs of the joints start tracking closely the desired valued.

다공질 규소의 라만 산란

김태균,김영유,서영석,조창호,나훈균 公州大學校 基礎科學硏究所 1998 自然科學硏究 Vol.7 No.-

양극반응 전류밀도를 변화시키면서 다공질 규소를 제작하여 라만산란을 관측하였다. 전류밀도가 증가함에 따라 라만신호는 520.5㎝-₁에서 멀어졌으며, 봉우리의 반치폭이 증가하였다. 또한 전류밀도 증가에 따라 원통형 다공질 결정의 직경은 감소함이 계산되었으며, 길이가 길어짐을 AFM으로 관찰하였다. The Raman scattering was studied from the porous silicons which were made by changing anodization current. As the current density was increased, it was observed that Raman was gradually far from the value of 520.5 cm￣¹and the full width half maximum increased. The decrease of radius of cylindrical porous crystal was calculated and the increase of its length was investigated through AFM.

頭痛에 관한 精神醫學的 硏究

羅澈,李吉弘,李在光,奇柏錫,李在禹,兪英植,李永植 서울醫大 1990 精神醫學 Vol.15 No.3

위암세포주에서 Recombinant Human Interferon-r와 Adriamycin의 투여순서가 항암효과에 미치는 영향

홍원선,손영숙,김창민,강윤구,이춘택,김유철,임영혁,남현석,이진오,강태웅 大韓免疫學會 1993 大韓免疫學會誌 Vol.15 No.-

Numerous previous studies, both in vitro and in vivo, have demonstrated that the cytotoxicity can be enhanced by the combination of chemotherapeutic agent and interferons(IFNs) in various types of cancer cells. We have previously reported that combined treatment of MKN-45, human gastric adenocarcinoma cells, with adriamycin(ADM) and recombinant human interferon-r(rh-IFN-r) increased in the cytotoxicity. In this study, the effects of combination timing of rh-IFN-r and ADM on the cytotoxicity against MKN-45 were investigated using MTT assay. MKN-45 was treated with rh-IFN-r and ADM in vitro on three schedules : Treat A ; rh-IFN-r and ADM were treated simultaneously, Treat B ; rh-IFN-r was treated 24 hours after the treatment with ADM, Treat C ; rh-IFN-r was treated for 72 hours and followed by the treatment with ADM. The survival of MKN -45 was inhibited by ADM dose-dependently. 102 and 103U/ml of rh-IFN-r significantly inhibited the survival of MKN-45(% survival : 35.1 ±-1.2% and 34.4 ±1.1% in Treat A and 42.5 ± 2.1% and 45.9-±2.5% in Treat C, respectively). However no difference in the survival was observed between 102 and 103U/ml of rh-IFN-r. Combined treatment with rh-IFN-r and ADM significantly augmented the cytotoxicity at low concentrations of ADM. Combined effects of rh-IFN-r and ADM were evaluated using IC30(,ag/ml) to ADM. IC30s of MKN-45 in Treat A, B and C at 102 U/ml of rh -IFN-r _ were 0.019 -?- 0.003, 0.045 :I:0.001 and 0.054 ± 0.012, respectively, while IC30 of MKN-45 treated with ADM alone was 0.052±0.004. IC30s of MKN-45 in ADM alone group, Treat A, Treat B and Treat C at 103U/ml of rh-IFN-r were 0.047 ±0.003, 0.004 -±0.001, 0.031 ±0.004 and 0.056 0.008, respectively. These results indicate IC30s of Treat A and B were significantly lower than those of ADM alone(p<0.05) and IC30s of Treat A was significantly lower than those of Treat B(p <0.01). IC30s of Treat C, however, were not different from those of ADM alone. From these results demonstrating that cytotoxic effects were increased by the combination of rh-IFN-r and ADM in the order, Treat A > Treat B> Treat C, it can be concluded that the simultaneous administration of rh-IFN-r and ADM may be the most effective method to combine these two therapeutic modalties.