뇌사환자의 갑상선 기능, 전신대사 및 중증도에 관한 연구

이영주,정금희,왕희정,문봉기,한연희,이영석 아주대학교 의과학연구소 1999 아주의학 Vol.4 No.1

Background and Objectives : Brain death may lead to hormonal depletion, metabolic derangement and multiple organ dysfunction. We have carried out present study to examine the effects of brain death on the thyroid function, metabolic indices, and the severity scoring systems. Methods : 13 adults patients admitted for organ donation or brain death evaluation were examined after brain death was confirmed. Thyroid hormones measured were .thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), and free thyroxine (FT4). The metabolic indices measured were arterial ketone body ratio (AKBR), lactic acid (LA), and base defiat (BD). as for reference to the severity scoring systems, APACHE Ⅲ and multiple organ failure score (MOFS) were assessed on the day of brain death confirmation. Arterial blood was drawn for all measurements. Results : As for the thyroid function, there were significant decreases in T3 (40.48±20.96 ng/dL) and T4 (3.47±2.15 ㎍/dL), but no significant change in FT4 (0.75±0.31 ng/dL) and TSH (1.12±1.37 uIU/mL) compared to the normal range. Significant decreases in AKBR (0.39±0.31) and BD (-9.46±5.83 m㏖/L), and significant increase in LA (2.57±2.46 m㏖/L) In metabolic indices, were shown, as for severity scoring systems, APACHE Ⅲ score (101.54±19.41) and MOF score (9.11±2.57) indicated a high mortality. There were significant correlation between thyroid hormones (r=0.565 -0.781) but no correlation among other indices. Also, significant inverse correlations were shown between base deficit and lactic acid (r=-0.660), APACHE Ⅲ score (r=-0.726) and MOF score (r=-0.604). The highest correlation was observed between APACHE Ⅲ score and MOF score (r=0.851). Conclusions : As for the thyroid function, significant decrease in T3 and T4, and almost normal range of FT4 and TSH imply the euthyroid sick syndrome. Abnormal finding of the metabolic parameters indicates an inhibition of the aerobic metabolic rate of the body as a whole. And the severity scoring parameters are compatible with high mortality.

간호실무에서 신봉이론(Espoused theories)에 대한 탐색적 연구

서문자,김혜숙,이은희,박영숙,조경숙,강현숙,임난영,김주현,이소우,조복희,이명하,지성애,하양숙,손영희,권성복,김희진,추진아 성인간호학회 2001 성인간호학회지 Vol.13 No.1

As a nursing practice involves nurses' actions in a specific context of health care, this study has focused on exploring the espoused theories in nursing practice within the action science perspectives, Espoused theories are the belief, principles, and rationale expressed by the practitioner as guiding her/his actions in a situation of practice. The data were analysed qualitatively and 25 elements of espoused theories of nursing action were identified and clustered into 6 categories. The 25 elements of espoused theories are as follows: The clinical nurse worked in wholistic and individual nursing, focussed on the patient's needed, comfort and supportive nursing (5 theories of nursing goal) ; excellent skills, knowledge based, assessment and data collection, explaining, educating or a scientific basis(6 theories of nursing intervention): advocacy, value oriented, treatment, account- ability and commitment(4 theories of nursing ethics) ; human respect. partnership, trust(3 theories of patient-nurse relationship) : knowledgable, accumulated clinical experiences and personally lived experiences. positive perspectives(4 theories of nurse), role of intervention. rewarding peer relationship(3 theories of situations) The above mentioned espoused theories are similar to that of nursing textbooks which students learned through basic nursing education and almost the same as the Acts ofa Nurse in Korean. However, we are doubtful whether nurses actually do as they think. Therefore. it is recommended to review the theories-in-use in order to and any discrepancies between the espoused theories and the reality of nursing actions

사료용 옥수수 연구 N. 조사료용 CNU 육성 교잡종 옥수수의 수량관련 주요특성

이희봉,정재영,김용일,박보영,지희정,문현귀 충남대학교 농업과학연구소 2006 농업과학연구 Vol.33 No.1

This study was carried out to compare a yield performance about CNU maize hybrids developed at the Maize Genetics and Breeding Lab, in Chungnam National University. Among the hybrids incorporated in the test, CNU 3 and 1 showed higher dry matter per 10a and lower kernel yield per 10a than check hybrid, Kwanganok. Hongchon 5 and Suwon169 showed higher kernel yield than Kwanganok. The average yield of CNU 3 hybrid in dry matter and CNU 4 in kernel yield were 2,106kg/10a and 854kg/10a in regional adaptability test, which were increased 33% and 8% compared with a check hybrid, respectively. Also, these hybrids had better stay green characteristics than check hybrid and showed moderately resistance to corn borer and leaf spot.

퍼지 이론을 이용한 다 개체 지능형 시스템의 동기화 제어기 설계 및 구현에 관한 연구

文熙根,金永卓,金秀貞,金寬衡,李尙培 한국해양대학교 산업기술연구소 2003 연구논문집 Vol.20 No.-

이 논문의 주제는 시스템의 두 DC 모터의 동기화를 위한 효과적인 PWM 듀티비 조절이다. 퍼지 제어기는 많은 불확실하고 복잡한 산업 공정에 성공적으로 적용되어왔다. 그래서 만약 목표지점의 길이가 다르다면 속도 조절을 위한 PWM 듀티비 조절을 위해 언어적인 퍼지 규칙을 이용한 퍼지 제어기를 적용했다. 그리고 미지의 플랜트를 위한 퍼지 제어기법을 이용한 미지의 변환 함수 시스템을 연구했다. 이 제어기는 시스템 동기화를 위한 PWM 듀티비 제어에 성공적으로 적용되어지고 있다. The subject of this paper is to control efficient PWM duty for two DC motor synchronousness in the system. Fuzzy controller have been successfully applied to many uncertain and complex industrial plant. So, It adapted fuzzy controller using compositional fuzzy rule so that change PWM duty for speed control if the length of destination is different. And for unknow plant, it is the study to make the unknow transfer function system with fuzzy control method. This controller has been successfully applied to PWM duty control for the system synchronousness.

봉선화 뿌리의 成分硏究

文永熙,高在鍾 조선대학교 약학연구소 1994 藥學硏究誌 Vol.16 No.1

Impatiens balsamina Linne(Balsaminaceae)known as "BONG SUN HWA" in Korea and used for treatment of Scrofulosis, Carbunculus and Dysenteria, etc.. From the roots of Impatiens balsamina, α-spinasterol and scopoletin were isolated and characterized by UV, IR, NMR, MS and chemical tests.

염지 중 베이컨육의 특성 변화

문영덕,문윤희,곽석범 慶星大學校 1989 論文集 Vol.10 No.2

Cured becon meats were manufactured from bacon using dry curing method with varing levels of sodium chloride. To study the changes of moisture content, water activity, pH, salt concentration, extractability of proteins, SDS-PAGE and ATPase activity of protein were investigated during curing period at 3±1℃. During the process of curing, the moisture content and water activity in bacon meat decreased while the pH and salt concentration increased. Extractabilities of protein and SDS-PAGE shows that changes in extractability of water soluble protein are less noticeable while the extractability of salt soluble protein depended on curing period. These changes were rapid in the high level concentration of sodium chloride. The ATPase activity of myofibril from cured bacon with low level of salt concentration demonstrated a higher sensitivity to ionic strength than that of myofibril from cured bacon with high levels.

韓國 中小製造企業의 輸出障碍要因과 輸出類型에 관한 硏究

文熙哲,林泳世 충남대학교 경상대학부설 경영경제연구소 1993 경영논집 Vol.9 No.1

전자장치 제어를 위한 Embedded Web의 구현

문영진,양희재 慶星大學校 1997 論文集 Vol.18 No.2

Embedded Web has been increasingly used in monitoring and controlling such small electronic equipments as vending machines and sensor products. Due to lots of limitations an embedded system may have encountered, however, the embedded Web server must have different functionalities compared to those of other ordinary Web servers like Apache, NCSA, and CERN HTTPD servers. This paper shows the required functionalities which a typical embedded Web server must provide, including the Server Side Include (SSI), periodic interactions between the server and clients by using Java appiets, and multicasting capabilities. A prototype embedded Web server is implemented on a 486SX embedded computer, and we present the internal structure of the server in detail.

猪笭湯이 實驗的 賢贓障碍家兎에 미치는 影響

文永熙,金美淑,李炳柱,林起龍 조선대학교 약학연구소 1991 藥學硏究誌 Vol.13 No.1

This study was attempted to investigate the effect of Jueryeong Tang(JRT) on renal failure of the rabbit treated with folate. Serum creatinine, blood urea nitrogen and serum uric acid in folate-treated rabbits were markedly increased and creatinine clearance was decreased by comparing with the normal group. JRT(900㎎/㎏) given orally produced significant reduction in concentration of both serum creatinine and blood urea nitrogen by comparing with the corresponding folate-treated group. while did increased clearly in creatinine clearance. The morphological changes of arcuate arteries and glomeruli evoked by folate treatment were almost returned to normal state after administration of JRT. (900㎎/㎏). These experimental results suggest that JRT may greatly improve renal failure of the rabbit induced by folate treatment.

Inducing apoptpsis by the inhibition of c-myb in oral squamous carcinoma cell line, KB cell

Lee,Jung-Chang 대한구강생물학회 2007 International Journal of Oral Biology Vol.32 No.4

Oral squamous cell carcinoma (OSCC) is the most commonmalignancy and is a major cause of worldwide cancer mortality.The proto-oncogene c-myb plays an important role in regulationof cell growth and differentiation, and it is expressed at highlevels in hematopoietic cells and many other types of cancers.However, the function of c-myb is not well known in OSCC.The present study aimed to reveal the function of c-myb and totest the alternation of cell growth and signaling by c-myb inOSCC. In this study, c-myb and dominant-negatibe myb(DN-myb) were expressed in an adenovirus-mediated gene deliverysystem to KB cells. The over-expressed c-myb broughtincreased cellular proliferation compared with control cells.However, DN-myb infected KB cells showed significantreduction of cell growth and enhanced induction of apoptosis toactivate PARP and caspase 9. c-myb induced increase of IGF-I,-II and IGF-IR expressions while DN-myb down-regulatedthese expression. Activation of ERK and Akt/PKB pathwaywas shown only in c-myb transduced cells. These findingssuggest that the role of c-myb in cell growth of oral cancer cellsis partially mediated through the modulation of IGFs, ERK andAkt/PKB. From this results, DN-myb is strongly recommendedas a curable gene for the treatment of c-myb dependentmalignancies such as OSCC.