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      • 在來山羊 수컷의 發育 및 屠體成績

        朴忠生,李吉旺,李用斌 慶尙大學校 1972 論文集 Vol.11 No.-

        生後 1개월령부터 8개월령 까지의 在來山羊 수컷 38두의 發育 및 屠體調査를 하였다. 生體重은 1개월령에 4.2kg이었고, 8개월령에는 14.5kg이었다. 屠體率은 37.2∼43.4%였으며, 頭重率은 4개월령 이후에 有意的으로 감소했으며, 生體重에 대한 第一胃容積의 比는 6개월령 까지 증가한 후 점차 감소되었다. 7∼8개월령, 山羊 10頭의 精肉率은 29.8%이었으며 兩側 背長筋 斷面績은 7.92㎠이었다. 屠體重, 頭重 및 第一胃容積과 生體重 間에는 高度의 有意的인 正相關이 있었다. The body growth and some carcass data of 38 male Korean native goats from 1 to 8 months of age have been studied. The body weight increased from 4.2kg at 1 month of 14.5kg at 8 months of age. The dressing % ranged from 37.2 to 43.4%. The head % decreased significantly(P<0.05) after 4 months of age. The rumen capacity per kg body weight increased significantly (P<0.05) to 6 moths of age and decreased thereafter. The lean % and loin-eye muscle area of both sides in goats from 7 to 8 months of age averaged 29.8% and 7.92㎠, respectively. There was a significant (P<0.01) correlation between body weight and carcass weight, head weight or rumen capacity.

      • KCI등재

        Endothelial Aquaporin-1 (AQP1) Expression Is Regulated by Transcription Factor Mef2c

        Yong Jiang,He Liu,Wen-jing Liu,Hai-bin Tong,Chang-jun Chen,Fu-gui Lin,Yan-hang Zhuo,Xiao-zhen Qian,Zeng-bin Wang,Yu Wang,Peng Zhang,Hong-liang Jia 한국분자세포생물학회 2016 Molecules and cells Vol.39 No.4

        Aquaporin 1 (AQP1) is expressed in most microvascula-ture endothelial cells and forms water channels that play major roles in a variety of physiologic processes. This study aimed to delineate the transcriptional regulation of AQP1 by Mef2c in endothelial cells. Mef2c cooperated with Sp1 to activate human AQP1 transcription by binding to its proximal promoter in human umbilical cord vein endothelial cells (HUVEC). Over-expression of Mef2c, Sp1, or Mef2c/Sp1 increased HUVEC migration and tube-forming ability, which can be abolished AQP1 knockdown. These data indicate that AQP1 is a direct target of Mef2c in regulating angiogenesis and vasculogenesis of endothelial cells.

      • Association of Matrix Metalloproteinase (MMP)-2 and -9 Expression with Extra-gastrointestinal Stromal Tumor Metastasis

        Wang, Chao,Ma, Hong-Xi,Jin, Mei-Shan,Zou, Ya-Bin,Teng, Yong-Liang,Tian, Zhuang,Wang, Hai-Ying,Wang, Yin-Ping,Duan, Xiu-Mei Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

        Matrix metalloproteinase (MMP)-2 and MMP-9 are important proteases involved in invasion and metastasis of various tumors. Extra-gastrointestinal stromal tumors (EGISTs) are rare neoplasms. This study was performed to assess MMP-2 and MMP-9 expression in EGIST tissue samples for association with clinicopathological data from the patients. Twenty-one surgical EGIST tissue specimens were collected for analysis of MMP-2 and MMP-9 expression using immunohistochemistry. MMP-2 and MMP-9 proteins were expressed in all of the epithelial cell types of EGISTs, whereas they were only expressed in 75% of the spindle cell type, although there was no statistically significant difference (p>0.05). Expression of MMP-2 and MMP-9 proteins was associated with tumor size, mitotic rate, tumor necrosis, and distant metastasis (p<0.05). MMP-2 expression was linked with MMP-9 levels (p<0.05). However, there was no correlation between MMP-9 expression and age, sex, primary site, or cell morphology in any of these 21 EGIST patients (p>0.05). Moreover, expression of MMP-2 and MMP-9 proteins increased with the degree of EGIST risk. This study provided evidence of an association of MMP-2 and MMP-9 expression with advanced EGIST behavior.

      • Biochar-supported nZVI (nZVI/BC) for contaminant removal from soil and water: A critical review

        Wang, Shengsen,Zhao, Mingyue,Zhou, Min,Li, Yuncong C.,Wang, Jun,Gao, Bin,Sato, Shinjiro,Feng, Ke,Yin, Weiqin,Igalavithana, Avanthi Deshani,Oleszczuk, Patryk,Wang, Xiaozhi,Ok, Yong Sik Elsevier 2019 Journal of hazardous materials Vol.373 No.-

        <P><B>Abstract</B></P> <P>The promising characteristics of nanoscale zero-valent iron (nZVI) have not been fully exploited owing to intrinsic limitations. Carbon-enriched biochar (BC) has been widely used to overcome the limitations of nZVI and improve its reaction with environmental pollutants. This work reviews the preparation of nZVI/BC nanocomposites; the effects of BC as a supporting matrix on the nZVI crystallite size, dispersion, and oxidation and electron transfer capacity; and its interaction mechanisms with contaminants. The literature review suggests that the properties and preparation conditions of BC (e.g., pore structure, functional groups, feedstock composition, and pyrogenic temperature) play important roles in the manipulation of nZVI properties. This review discusses the interactions of nZVI/BC composites with heavy metals, nitrates, and organic compounds in soil and water. Overall, BC contributes to the removal of contaminants because it can attenuate contaminants on the surface of nZVI/BC; it also enhances electron transfer from nZVI to target contaminants owing to its good electrical conductivity and improves the crystallite size and dispersion of nZVI. This review is intended to provide insights into methods of optimizing nZVI/BC synthesis and maximizing the efficiency of nZVI in environmental cleanup.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Aggregation and passivation of nZVI can be alleviated by surfactants and doping methods. </LI> <LI> BC hinders corrosion and improves the dispersion and electron transfer of nZVI. </LI> <LI> Properties of nZVI depend on those of the BC, feedstock and pyrogenic temperature. </LI> <LI> BC enhances electron transfer from nZVI to the contaminants due to the presence of quinone and graphene moieties. </LI> <LI> nZVI/BC shows strong ability to remove HMs, nitrates, and organic contaminants in soil and water. </LI> </UL> </P>

      • KCI등재

        Endothelial Aquaporin-1 (AQP1) Expression Is Regulated by Transcription Factor Mef2c

        Jiang, Yong,Liu, He,Liu, Wen-jing,Tong, Hai-bin,Chen, Chang-jun,Lin, Fu-gui,Zhuo, Yan-hang,Qian, Xiao-zhen,Wang, Zeng-bin,Wang, Yu,Zhang, Peng,Jia, Hong-liang Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.4

        Aquaporin 1 (AQP1) is expressed in most microvasculature endothelial cells and forms water channels that play major roles in a variety of physiologic processes. This study aimed to delineate the transcriptional regulation of AQP1 by Mef2c in endothelial cells. Mef2c cooperated with Sp1 to activate human AQP1 transcription by binding to its proximal promoter in human umbilical cord vein endothelial cells (HUVEC). Over-expression of Mef2c, Sp1, or Mef2c/Sp1 increased HUVEC migration and tube-forming ability, which can be abolished AQP1 knockdown. These data indicate that AQP1 is a direct target of Mef2c in regulating angiogenesis and vasculogenesis of endothelial cells.

      • KCI등재

        Salivary Pepsin as an Intrinsic Marker for Diagnosis of Sub-types of Gastroesophageal Reflux Disease and Gastroesophageal Reflux Disease-related Disorders

        ( Yan-jun Wang ),( Xiu-qiong Lang ),( Dan Wu ),( Yu-qin He ),( Chun-hui Lan ),( Xiao-xiao ),( Bin Wang ),( Duo-wu Zou ),( Ji-min Wu ),( Yong-bin Zhao ),( Peter W Dettmar ),( Dong-feng Chen ),( Min Yan 대한소화기 기능성질환·운동학회 2020 Journal of Neurogastroenterology and Motility (JNM Vol.26 No.1

        Background/Aims To determine the value of salivary pepsin in discriminating sub-types of gastroesophageal reflux disease (GERD) and GERD-related disorders. Methods Overall, 322 patients with different sub-types of GERD and 45 healthy controls (HC) were studied. All patients took Gastroesophageal Reflux Disease Questionnaire (GerdQ) and underwent endoscopy and 24-hour esophageal pH monitoring and manometry. Salivary pepsin concentration (SPC) was detected by using colloidal gold double-antibody immunological sandwich assay. Oral esomeprazole treatment was administrated in the patients with non-erosive reflux disease (NERD) and extra-esophageal symptoms (EES). Results Compared to HC, patients with erosive esophagitis, NERD, EES, EES plus typical GERD symptoms, or Barrett’s esophagus had a higher prevalence of saliva and SPC (all P < 0.001). There was no significant difference in the positive rate for pepsin in patients with functional heartburn or GERD with anxiety and depression, compared to HC. After esomeprazole treatment, the positive rate and SPC were significantly reduced in NERD (both P < 0.001) and in EES (P = 0.001 and P = 0.002, respectively). Of the 64 NERD patients, 71.9% (n = 46) were positive for salivary pepsin, which was significantly higher than the rate (43.8%, n = 28) of pathological acid reflux as detected by 24-hour esophageal pH monitoring (P = 0.002). Conclusions Salivary pepsin has an important significance for the diagnosis of GERD and GERD-related disorders. Salivary pepsin and 24-hour esophageal pH monitoring may complement with each other to improve the diagnostic efficiency.

      • KCI등재

        Rational Approximation of Fractional Order Systems by Vector Fitting Method

        Bin Du,Yong Wang,Yiheng Wei,Shu Liang 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.1

        A novel method for approximating fractional order systems is presented. Vector fitting is involved in thismethod. As the basis of approximation of fractional order systems, approximation of fractional order operators ismostly achieved by curve fitting in frequency domain, such as the well-known Oustaloup’s method. However, thesemethods have several serious defects in principle. A new perspective based on system identification is adoptedto deal with approximation of fractional order operators in this paper. Moreover, nonzero initial condition forapproximating fractional order systems is considered. And the proposed assignment of initial values for the Caputocase offers an effective solution for the simulation with nonzero initial condition. Finally, numerical examples aregiven to verify the efficiency of the proposed method.

      • KCI등재

        Comparative Analysis of Water Stress-Responsive Transcriptomes in Drought-Susceptible and -Tolerant Wheat (Triticum aestivum L.)

        Yong Chun Li,Fan Rong Meng,Chun Yan Zhang,Ning Zhang,Ming Shan Sun,Jiang Ping Ren,Hong Bin Niu,Xiang Wang,Jun Yin 한국식물학회 2012 Journal of Plant Biology Vol.55 No.5

        To understand better the mechanisms that regulate the water stress response in wheat, we conducted a comparative analysis of transcript profiles in roots from two wheat genotypes -- drought-tolerant ‘Luohan No. 2’ (LH)and drought-susceptible ‘Chinese Spring’ (CS). In LH roots,3831 transcripts displayed changes in expression of at least two-fold over the well-watered control when drought treatment was applied. Of these, 1593 were induced while 2238 were repressed. Relatively fewer transcripts were drought-responsive in CS; i.e., 1404 transcripts were induced and 1493 were repressed. In common between LH and CS,569 transcripts were induced and 424 transcripts were repressed. In all, 689 transcripts (757 probe sets) identified from LH and 537 transcripts (575 probe sets) from CS were annotated and classified into 10 functional categories. Among those annotated transcripts from LH and CS that had fold-change ratios of at least 4, 92 induced transcripts were common to both, while 23 transcripts were specifically induced in LH. Gene ontology analysis of these induced genes showed highly significant enrichment for multiple terms related to abiotic stimuli, organic acid biosynthesis,and lipid metabolism. This suggests that these gene groups play important roles during the stress response in LH and CS, and might also be responsible for differences in drought tolerance between those genotypes.

      • Identification and Characterization of Baculoviruses isolated from Spodoptera litura

        Yong Wang,Jae Young Choi,Jong Yul Roh,Qin Liu,Xueying Tao,Jong Bin Park,Soo Dong Woo,Byung Rae Jin,Yeon Ho Je 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.10

        We isolated two baculoviruses, Spodoptera litura granulovirus (SlGV) and S. litura nucleopolyhedrovirus (SlNPV) in the dead larvae of S. litura. The granule of SlGV were ovoidal shape with an approximate measure of 240-340 nm×140-180 nm, and each granule contained one single rod-shape virion with a mean size of 180-200 nm×20-40 nm. Whereas, the polyhedra of SlNPV were irregular in shape with a approximate diameter of 1.0-1.5 ㎛, and numerous virions comprised of the multinucleocapsid were contained in each polyhedra. The major component of occlusion bodies produced by SlGV and SlNPV were about 29 and 30 kDa, respectively. When the phylogenic relationship between these viruses were analyzed using the nucleotide sequences of granulin gene from SlGV and polyhedrin gene from SlNPV, they were not closely related to each other. We also found that the two viruses showed similar insecticidal activity against 2nd instar larvae of Spodotera litura in terms of dose-response, but SlGV showed much longer LT50 than that of SlNPV. The two baculoviruses might be cooperatively be applied as biological control agent for the control of S. litura

      • SCIESCOPUS

        An effective online delay estimation method based on a simplified physical system model for real-time hybrid simulation

        Wang, Zhen,Wu, Bin,Bursi, Oreste S.,Xu, Guoshan,Ding, Yong Techno-Press 2014 Smart Structures and Systems, An International Jou Vol.14 No.6

        Real-Time Hybrid Simulation (RTHS) is a novel approach conceived to evaluate dynamic responses of structures with parts of a structure physically tested and the remainder parts numerically modelled. In RTHS, delay estimation is often a precondition of compensation; nonetheless, system delay may vary during testing. Consequently, it is sometimes necessary to measure delay online. Along these lines, this paper proposes an online delay estimation method using least-squares algorithm based on a simplified physical system model, i.e., a pure delay multiplied by a gain reflecting amplitude errors of physical system control. Advantages and disadvantages of different delay estimation methods based on this simplified model are firstly discussed. Subsequently, it introduces the least-squares algorithm in order to render the estimator based on Taylor series more practical yet effective. As a result, relevant parameter choice results to be quite easy. Finally in order to verify performance of the proposed method, numerical simulations and RTHS with a buckling-restrained brace specimen are carried out. Relevant results show that the proposed technique is endowed with good convergence speed and accuracy, even when measurement noises and amplitude errors of actuator control are present.

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