http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Zhang, Heyao,He, Zhao,Song, Jinliang,Liu, Zhanjun,Tang, Zhongfeng,Liu, Min,Wang, Yong,Liu, Xiangdong Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.6
Irradiation-induced damage of binderless nanoporous-isotropic graphite (NPIG) prepared by isostatic pressing of mesophase carbon microspheres for molten salt reactor was investigated by 3.0 MeV He<sup>+</sup> irradiation at room temperature and high temperature of 600 ℃, and IG-110 was used as the comparation. SEM, TEM, X-ray diffraction and Raman spectrum are used to characterize the irradiation effect and the influence of temperature on graphite radiation damage. After irradiation at room temperature, the surface morphology is rougher, the increase of defect clusters makes atom flour bend, the layer spacing increases, and the catalytic graphitization phenomenon of NPIG is observed. However, the density of defects in high temperature environment decreases and other changes are not obvious. Mechanical properties also change due to changes in defects. In addition, SEM and Raman spectra of the cross section show that cracks appear in the depth range of the maximum irradiation dose, and the defect density increases with the increase of irradiation dose.
Rainfall-induced Landslide Hazard Analysis Based on GIS in Yanbian Region, China
Liu,Xiu Xuan,Quan, He Chun,이병걸 대한공간정보학회 2017 대한공간정보학회지 Vol.25 No.4
This paper mainly studies landslide hazard in Yanbian region,8 landslide factors of soil moisture content, hydrogeology, land use type, slope, slope aspect, fault, river and rainfall are analyzed in the area of Yanbian region. Using the analytic hierarchy process (AHP), the relative weights of 8 landslide factors were obtained, and the internal weights of each factor were determined by the data; the rainfall factors were then divided into three categories such as average annual rainfall, average flood season rainfall, and the maximum average rainfall. And the comparison of the rainfall factors was made. Finally based on the results of these weights to the remote sensing technology(RS) and geographic information system(GIS) technology combined to evaluate its area, we are mapping the risk assessment area for landslide hazard in Yanbian region. According to the map analysis, figure in the dangerous hierarchies result in accordance with the historical landslides is better. At the same time. landslides and hazard area of statistical data analysis showed that the AHP method combined with GIS technology is suitable for promoting the Yanbian regional landslide hazard assessment.
The Media Literacy of Residents in Southwestern China During the COVID-19 Epidemic
Shan He(Shan He),Lili Yao(Lili Yao),Xingyu Zhao(Xingyu Zhao),Weiwei Liu(Weiwei Liu) 아시아사회과학학회 2023 International Science Research Vol.3 No.2
Objective To measure residents’ abilities to acquire, analyze and evaluate information on media in southwestern China and to explore its predictive factors. Methods The convenience sampling method was used. A web-based questionnaire survey was conducted among 774 residents during the Spring Festival in 2020. Results Young, highly educated, unmarried, high-income, and urban residents preferred to seek and acquire information about COVID-19 epidemic through new media channels. Elderly residents tended to obtain information through television. Residents with low educational background and rural residents were more dependent on community information media. To analyze residents’ abilities in the judgement of 15 statements about COVID-19, residents with a master’s degree or above (OR = 2.755, [95% CI 1.160-6.542]) had better media literacy in identifying false health information released on social networking. Rural residents (OR = 0.609, [95% CI 0.433-0.855]) had lower media literacy. The total score decreased by 2.6% for every one-year increase of age. Conclusion Residents’ abilities to acquire, analyze and evaluate information were affected by their demographic characteristics in southwestern China. The authorities and local communities should develop different approaches of information dissemination, with the help of traditional and new media. It is important to improve the level of residents' media literacy, in order to achieve better effect in information dissemination and reception.
Solidification of uranium mill tailings by MBS-MICP and environmental implications
Niu Qianjin,Li Chunguang,Liu Zhenzhong,Li Yongmei,Meng Shuo,He Xinqi,Liu Xinfeng,Wang Wenji,He Meijiao,Yang Xiaolei,Liu Qi,Liu Longcheng 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.10
Uranium mill tailing ponds (UMTPs) are risk source of debris flow and a critical source of environmental U and Rn pollution. The technology of microbial induced calcium carbonate precipitation (MICP) has been extensively studied on reinforcement of UMTs, while little attention has been paid to the effects of MICP on U & Rn release, especially when incorporation of metakaolin and bacillus subtilis (MBS). In this study, the reinforcement and U & Rn immobilization role of MBS -MICP solidification in different grouting cycle for uranium mill tailings (UMTs) was comprehensively investigated. The results showed that under the action of about 166.7 g/L metakaolin and ~50% bacillus subtilis, the solidification cycle of MICP was shortened by 50%, the solidified bodies became brittle, and the axial stress increased by up to 7.9%, and U immobilization rates and Rn exhalation rates decrease by 12.6% and 0.8%, respectively. Therefore, the incorporation of MBS can enhance the triaxial compressive strength and improve the immobilization capacity of U and Rn of the UMTs bodies solidified during MICP, due to the reduction of pore volume and surface area, the formation of more crystals general gypsum and gismondine, as well as the enhancing of coprecipitation and encapsulation capacity
He, Feng,Wen, Hai-Shen,Li, Ji-Fang,Yu, Da-Hui,Ma, Rui-Qin,Shi, Dan,Mu, Wei-Jie,Zhang, Yuan-Qing,Hu, Jian,Liu, Miao,Han, Wei-Guo,Zhang, Jia-Nan,Wang, Qing-Qing,Yuan, Yu-Ren,Liu, Qun Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.4
Gonadotropin-releasing hormone receptor (GnRHR) gene is expressed at the anterior pituitary gland and plays a key role in gonad development. This study aimed to investigate molecular genetic characteristics of the GnRHR gene and elucidate the effects of single nucleotide polymorphisms (SNPs) of GnRHR gene on sex steroid level in Japanese flounder (Paralichthys olivaceus). We used polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP) and sequencing of the GnRHR gene in 75 individuals. We identified three SNPs in the GnRHR gene: P1 locus (C759A and C830T) in the coding region of exon2 which were both linked together and P2 locus (G984T) in the coding region of exon3, which added a new transcript factor (ADR1) and a new methylation site (CG). Only C830T of P1 leads to amino acid changes Thr266Ile. Statistical analysis showed that P1 was significantly associated with $17{\beta}$-estradiol ($E_2$) level (p<0.01) and gonadosomatic index (GSI) (p<0.05). Individuals with genotype BB of P1 had significantly higher serum $E_2$ levels (p<0.01) and GSI (p<0.05) than those of genotype AA or AB. Another SNP, P2, synonymous mutation, was significantly associated with GSI (p<0.05). Individuals with genotype AB of P2 had significantly higher GSI (p<0.05) than that of genotype AA. In addition, there was a significant association between one diplotype based on three SNPs and reproductive traits. The genetic effects for both serum $E_2$ level and GSI of diplotype D4 were super diplotypes (p<0.05). These results suggest that the SNPs in Japanese Flounder GnRHR are associated with $E_2$ level and GSI.
Liu, Fen,Wei, Wen-Qiang,Cormier, Robert T.,Zhang, Shu-Tian,Qiao, You-Lin,Li, Xin-Qing,Zhu, Sheng-Tao,Zhai, Yan-Chun,Peng, Xiao-Xia,Yan, Yu-Xiang,Wu, Li-Juan,He, Dian,He, Yan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4
Background: The prostaglandin-endoperoxide synthase 2 (PTGS2) and phospholipase A2 group IIA (PLA2G2A) genes encode enzymes that are involved in arachidonic acid and prostaglandin biosynthesis. Dysregulation of both genes is associated with inflammation and carcinogenesis, including esophageal squamous cell carcinoma (ESCC). We therefore hypothesized that there is an association between single nucleotide polymorphisms (SNPs) in these genes and susceptibility to ESCC. Methods: We performed a gene-wide tag SNP-based association study to examine the association of SNPs in PTGS2 and PLA2G2A with ESCC in 269 patients and 269 healthy controls from Taihangshan Mountain, Henan and Hebei Provinces, the rural area of China which has the highest incidence of esophageal cancer in the world. Thirteen tag SNPs in PLA2G2A and 4 functional SNPs in PTGS2 were selected and genotyped using a high-throughput Mass Array genotyping platform. Results: We found a modest increased risk of ESCC in subjects with the PTGS2 rs12042763 AA genotype (OR=1.23; 95% CI, 1.00-3.04) compared with genotype GG. For PLA2G2A, a decreased risk of ESCC was observed in subjects with the rs11677 CT (OR=0.51, 95%CI, 0.29-0.85) or TT genotype (OR=0.51, 95%CI, 0.17-0.96) or the T carriers (CT+TT) (OR=0.52, 95%CI, 0.31-0.85) when compared with the CC genotype. Also for PLA2G2A, rs2236771 C allele carriers were more frequent in the control group (P=0.02). Subjects with the GC (OR=0.55, 95%CI, 0.33-0.93) or CC genotype (OR=0.38, 95% CI, 0.16-0.94) or the C carriers (GC+CC) (OR=0.52, 95%CI, 0.32-0.85) showed a negative association with ESCC susceptibility. Conclusions: Our results suggest that PTGS2 and PLA2G2A gene polymorphisms may modify the risk of ESCC development.
Defects evolution and element segregation of Ni-Mo-Cr alloy irradiated by 30 keV Ar ions
Liu Min,Liu Wenguan,He Xiujie,Gao Yantao,Liu Renduo,Zhou Xingtai 한국원자력학회 2020 Nuclear Engineering and Technology Vol.52 No.8
In present study, TEM foils of Ni-Mo-Cr alloy were directly irradiated with 30 keV Ar ions to allow direct characterization. The defects evolution and element segregation after irradiation were investigated by TEM and HAADF-EDS linear scanning. At low irradiation doses (1.38 and 2.76 dpa), black dots were formed and grew with increasing dose. Complicated defects including peas-shaped dislocation loops, polygon dislocation networks and large loops were visible in samples irradiated to high doses (13.8 and 27.6 dpa). Meanwhile, dislocation channels appeared, in which defects were swept out. Significant Mo depletions at dislocation lines and grain boundaries were induced by irradiation due to large misfits between Mo-Ni atoms and high content of Mo.
Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2.
Liu, Kangdong,Park, Chanmi,Li, Shengqing,Lee, Ki Won,Liu, Haidan,He, Long,Soung, Nak Kyun,Ahn, Jong Seog,Bode, Ann M,Dong, Ziming,Kim, Bo Yeon,Dong, Zigang IRL Press] ; Oxford University Press 2012 Carcinogenesis Vol.33 No.7
<P>Phosphatidylinositol 3-kinase (PI3-K) amplification and phosphatase and tensin homolog (PTEN) deletion-caused Akt activation contribute to the development of prostate cancer. Mammalian target of rapamycin complex 2 (mTORC2) is a kinase complex comprised of mTOR, Rictor, mSin1, mLST8/G관L and PRR5 and functions in the phosphorylation of Akt at Ser473. Herein, we report that mTORC2 plays an important role in PC3 androgen refractory prostate cell proliferation and anchorage-independent growth. Aloe-emodin, a natural compound found in aloe, inhibited both proliferation and anchorage-independent growth of PC3 cells. Protein content analysis suggested that activation of the downstream substrates of mTORC2, Akt and PKC관, was inhibited by aloe-emodin treatment. Pull-down assay and in vitro kinase assay results indicated that aloe-emodin could bind with mTORC2 in cells and inhibit its kinase activity. Aloe-emodin also exhibited tumor suppression effects in vivo in an athymic nude mouse model. Collectively, our data suggest that mTORC2 plays an important role in prostate cancer development and aloe-emodin suppresses prostate cancer progression by targeting mTORC2.</P>