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      • KCI등재

        치성낭종으로부터 유래된 편평상피세포암종 : Report of a Case & Review of Literatures

        권혁진,현재훈,박형국,김용각 大韓顎顔面成形再建外科學會 1997 Maxillofacial Plastic Reconstructive Surgery Vol.19 No.2

        Odontogenic cysts are relatively common pathologic lesions found in the oral and perioral structures, but the case of squamous cell carcinoma arising from those cysts are very uncommon. After first reported of that case in 1889 by Herman, Schwimmer collected 56 cases of previously reported squamous cell carcinoma arising in residual odontogenic cyst during about past one century. More than 60% of cases of carcinoma developing in odontogenic cysts arising in inflammatory periapical or residual cyst, and these tumors are usually well-differentiated with relatively good prognosis, and often are diagnosed as benign lesion in radiographic or clinical examination, therefore definitive diagnosis must be made by histologic examintation. We report a case and review the literatures, in our case, 78-year old woman were clinically and radiographically diagnosed as residual odontogenic cyst. But in histologic examination after enucleation of lesion, mass of squamous cell carinoma were observed, but in other area, typical cyst wall and lining epithelium were observed. And in some area, carcinoma in situ and invading squamous cell carcinoma into the lining epithlium were also observed.

      • CATIA를 이용한 고속가공용 탭핑머신의 구조해석

        권혁홍,김지용,하종국 대진대학교 2002 大眞論叢 Vol.10 No.-

        In this study the structure analysis of tapping m/c is developed to improve dynamic characteristics. To this purpose a tapping m/c is mathematically modelled and dynamic response analysis of the model are investigated by use of Finite Element Method(FEM). The investigation procedures are as follows. The finite element modelling of the tapping m/c is done with triangular and rectangular plate elements and each node of the elements has 6 degrees of freedom. And this model is idealized as a forced vibration system under impulse load by cutting force. Model parameters, natural frequency and mode shape, and dynamic response for displacement and stress are analyzed by use of mode superposition method. To reduce computing time of dynamic response analysis, lower vibration mode is analyzed with master-DOF and mass participation factor. In this case maximum relative displacement is occured at 17.483 Hz in the right column.

      • 앉기 자세와 수근관 증후군의 상관관계에 관한 고찰 : A Literature Review

        권혁철,공진용 한국전문물리치료학회 2002 한국전문물리치료학회지 Vol.9 No.3

        The objectives of this study was to investiage the effects of sitting posture on carpal tunnel syndrome. Carpal tunnel syndrome (CTS) continoes to be one of the most widely publicized maladies of the cumulative trauma disorder. Many studies have reported a positive association between CTS and highly repetitive work, high force, and poor posture. High force and repetitive work have especially been associated with CTS, but the evidence for work being a primary cause of CTS is strongest when these factors are combined. In addition to carpal tunnel syndrome, hand, wrist, and other disorders are attributed to these work-related movements. Such disorders are referred to as repetitive stress injuries, cumulative trauma disorder, overuse syndromes, and chronic upper limb pain syndrome. Incorrect posture also may play a role in the development of CTS in people who work at a computer and other types of keyboards. The tendency to roll the shoulders forward, round the lower back, and thrust the chin forward can shorten the neck and shoulder muscles, compressing nerves in the neck. This, in turn, can affect the wrist, fingers, and hand. The treatment and prevention of carpal tunnel syndrome continue to be approached with a segmental view of the human body. For example, the most common ergonomic solution for carpal tunnel syndrome associated with keyboard use is to keep the wrists in a neutral position by using a wrist rest in front of the keyboard and good sitting posture.

      • KCI등재후보

        국내 살모넬라 분리주에서 spvR 유전자 분포와 단일 뉴클레오티드 다형 연구

        권혁준,박경윤,박주연,박용호,김선중,유한상 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

        목적 : 지금까지 병원성 살모넬라를 확인하기 위해 분자량이 큰 플라스미드의 존재 유무를 확인하여 왔으나 살모넬라 혈청형 및 검출 방법에 따라 양성율에 큰 차이를 보이고 있고, 일부 병원성 살모넬라 분리주에서 병원성 플라스미드가 관찰되지 않아 spv 유전자들의 유무에 대한 아른 확인방법이 필요하다. 본 실험은 국내 동물 유래 주요 살모넬라 혈청형에서 spvR 유전자의 분포를 알아보고, 병원성 살모넬라 분자진단을 위한 분자표지로써의 가치를 평가하기 위해 실행하였다. 재료 및 방법 : 국내 가축 유래 S. lyphimurium (ST, 26주), S. enteritidis (SE, 10주), S. pullorum (SP, 40주), S. gallinarum (SG, 53주)에 대해 GenBank에 등록된 ST, SE, SP의 spvR 유전자를 비교하여 ST와 SE 간에 차이를 보이는 single nucleotide polymorphism (SNP, 625번 뉴클레오티드)을 포함하도록 시발자를 합성하여 집락-PCR을 수행하였다. 증폭 산물(194bp)은 자동 염기서열장치를 이용하여 염기서열을 결정하였고, 제한효소인 MseI을 사용하여 PCR-RFLP를 실시하였다. 결과 : 집락-중합효소연쇄반응 결과 SP, SG, SE의 모든 (100%) 분리주에서 특이 증폭산물이 검출되었으나 ST의 경우 19주(73%)에서만 증폭되었다. 특히 병원성 관련 플라스미드가 관찰되지 않았던 SP 4주에서 특이적인 증폭산물이 검출되었다. 염기서열 분석결과 SE, SG, SP는 625번 뉴클레오티드에 아데닌을, ST는 구아닌을 가지고 있어 PCR-RFLP를 이용하여 쉽게 구분할 수 있었다. 결 론 : spvR에 대한 집락-중합효소연쇄 반응법은 병원성 플라스미드 검출법보다 SE, SP, SG 병원성 주를 신속하게 검출하는데 유용하고, 625번 뉴클레오티드의 SNP는 ST와 SE, SG, SP를 구분하는 분자표지로 사용될 수 있을 것으로 기대되며, ST에 비해 SE는 진화적으로 SG와 SP에 가까운 것으로 생각되었다. Background : The Salmonella virulence plasmid (spv) genes (spvR, A, B, C and D) on the large virulence plasmids of pathogenic Salmonella serotypes can replace the virulence of the whole plasmid. Recently, virulence plasmid-negative pathogenic Salmonella isolates were isolated. However, positive rates of spv genes among Korean Salmonella serotypes have been obscure. spv genes are conserved in compared to other virulence genes but there are single nucleotide polymorphisms (SNPs) conserved in only certain serotype. Such SNPs are useful for differentiation and understanding evolution of certain serotypes. Materials and Methods : Salmonella serotypes isolated from live stocks [Salmonella typhimurium (ST, 26), S. enteritidis (SE, 10), S. gallinarum (SG, 40) and S. pullorum (SP, 53)] were used for colony-PCR. A primer set covering single nucleotide polymorphism (SNP) at 625th nucleotide of spvR was designed. The nucleotide sequences of amplicons were determined by cyclic sequencing method and RFLP was performed by using MseI. Results : All isolates of SE, SG and SP, including four plasmid-negative isolates, showed specific amplicons but not all of ST (19/26, 73%) were positive to spvR. Based on the nucleotide sequence of 625th nucleotide and PCR-RFLP, SE, SG and SP [A(625)] and ST [G(625)] could be differentiated. Conclusion : spvR can be used as a molecular marker to detect virulent SE, SG, SP and the SNP may be useful for differentiation of SE, SG, SP and ST. According to the SNP study SE may be evolutionarily closer to SG and SP than ST.

      • KCI등재후보

        『구입유물공개전』 전시유물 보존처리 : 금속유물을 중심으로

        권혁남,이용희,김종오 국립중앙박물관 2000 박물관보존과학 Vol.2 No.-

        국립중앙박물관에서는 국내외에서 구입한 유물들을 전시하기 위하여 보존처리를 실시하였다. 처리유물은 금속제 유물을 비롯하여 목제, 회화, 목·칠기 등 다양한데, 이중 금속유물 42점의 보존처리 내용을 재질별로 소개하였다. 유물의 현재 상태를 파악하기 위해 현미경 조사 및 X-선 촬영을 실시하였으며 재질에 따라 이물질 제거 방법, 안정화 처리 방법 등의 처리 방향을 설정하였다. 또한 역사적 자료를 보존하고 일반인들에게 전시할 수 있는 조치를 취하였다. For exhibition, conducted conservation treatment for a variety of collections acquired at home and abroad such as metallic objects, wooden-ware, paintings and lacquer-ware. Conservation treatment methods for 42 metallic objects were introduced for material types. X-ray and microscopic method were used to identify the current state of the collections and in some case if necessary, various foreign particle removing and stabilization method were used depending on material type. Historical data were stored and exhibited to public.

      • 過共晶 Al-Si 合金의 振動鑄造에 關한 硏究

        朴龍鎭,權赫茂 弘益大學校 1977 弘大論叢 Vol.9 No.-

        The melt of hyper eutectic Al-Si alloy was poured into the metallic mold and it was solidified while vibrating by megnetic vibrating. The results obtained can be summarized as follows: 1. If the mold was vibrated, the primary silicon grain was refined to proportion with the strength of vibration 2. When the force of vibrating was change, the effect of refining of theprimary silicon was refined to proportional to streight line with-out modification of bath. 3. The condition of primary crystal was not mixed the eutectic and was grain-refined. 4. The tensile strength by vibrational casting was proportional on the forces of vibration in the ilmited vibrational range. 5. It was found that the change of elongation of the vibrationgal was inversely proportional to the tensile strength of the casting.

      • 염산증기 흡입에 의해 발생한 화학성 폐렴 1예

        장재혁,원경준,권세훈,하성일,권용은,이승일,윤성호 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

        A 38-year-old man with dyspnea admitted to the emergency department after exposure to hydrochloric acid in pharmaceutical product manufacturer. Crackle was auscultated in both lung fields in initial physical examination. Chest radiograph showed consolidation and diffuse parenchymal infiltration in both lung fields. Arterial blood gas analysis showed severe hypoxia. This patient was treated by mechanical ventilation, corticosteroid, antibiotics and bronchodilators and was improved completely in a week after the admission. The authors report a rare case of chemical pneumonitis caused by hydrochloric acid.

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