수주생산환경의 생산계획 및 통제 시스템에서 동적이벤트의 효과적인 처리방법에 관한 연구

하성일,서준용,김재균,고재문 대한산업공학회 1999 대한산업공학회 추계학술대회논문집 Vol.1999 No.10

마미총 부위에서 발생한 말초 신경상피종의 국소전이 1례

하성일,이종수,이승재,박효일 인제대학교 1995 仁濟醫學 Vol.16 No.2

본 교실에서는 요통 및 양하지 방사통으로 내원한 23세 여자환자에서 초기 방사선학적 검사상 요천추부 경막내 종양으로 진단되어 수술을 시행한 결과, 조직검사상 말초 신경상피종으로 확인된 후 지속적인 치료에도 불구하고 국소 임파절 및 폐 전이로 사망한 드문 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. An unusual case of the intraspinal peripheral neuroepithelioma arising from the cauda equina is reported. The patient, a 23-year old female, suffered from low back pain with radiation to the both legs. Radiologic imaging studies of lumbosacral spine showed the intradural extramedullary mass lesion on the cauda equina which was excised surgically, but recurred rapidly. It could be diagnosed by the histopathologic findings. The postoperative radiotherapy and chemotherapy were administered. But, she had lymph node metastases, local invasion and large mass in the lung. We report this rare case with review of the literatures.

신라의 ‘예악(禮樂)’ 사상이 현대음악교육에 주는 교육적 의미

하성일 한국음악교육학회 2011 음악교육연구 Vol.40 No.1

This study is focused on the analysis of problems, the searching for a model to 'YE·AK' ideal in Shilla, and presentation of new direction in Korean music education. Korean music education has been in dangerous situation maintained in knowledge for the entrance examination, which has destroyed the main purpose of music education. Shilla dynasty was based on the principle of duty and humanity. The principle of duty and humanity was considered as life itself. Wharang, the organization of education for fit person was served as training school for fighter at war and for student, artist and mourner at peace. Especially the chief of Wharang, Fungwhalzu devoted his private desire and goal to the benefit of public. The contents of this education were swordsmanship, history, song and dance. In these contents song was the most important thing. Song and dance encourage human emotion to be good conditions and enforce the tie of communities. In this point of view Shilla dynasty promoted widely song and dance. Eungsungsue, a government office to promote song and dance was established. The person who can sing and dance well was esteemed by the society. Our music education should be re-recognized in the importance and improved in the entrance examination. Sufficient educational period for music must be guaranteed. In many curriculum including talent music educational course have to be essential. In addition music educational course should be changed from theoretical and functional to activities and enjoyable. Government and educational authorities must supply at administrative and financial supports in music education. The condition of advanced musical educational system should be venture marketed. The research of musical educational system in traditional culture must be inquired and applied to the present music education. Now the reform and normalization of Korean music education are the most important thing in Korean education.

마이코박테리움을 신속하게 배양할 수 있는 성장 인자에 관한 연구

하성일,박강균,석현수,신정섭,신동필,권민오,박연준,Ha, Sung-Il,Park, Kang-Gyun,Suk, Hyun-Soo,Shin, Jeong-Seob,Shin, Dong-Pil,Kwon, Min-O,Park, Yeon-Joon 대한임상검사과학회 2019 대한임상검사과학회지(KJCLS) Vol.51 No.2

Mycobacterium은 느리게 성장한다. 따라서 고체배지는 8주, 액체배지는 6주 동안 사용하여야 한다. 이 연구의 목적은 Mycobacterium을 빠르게 성장시킬 수 있는 성장 인자를 찾고, 신속한 동정을 위한 고체배지를 개발하는 데 도움을 주는 것이다. $Difco^{TM}$ Mycobacteria 7H11 agar (Becton, Dickinson and Company)에 activated charcoal, defibrinated sheep blood, L-ascorbic acid를 첨가하여 10종의 Mycobacteria 가지고 Mycobacterium 성장 인자 3가지를 평가하였다. 집락의 검출 시간 및 판독 용이성을 현재의 방법과 비교하였다. 빠르게 성장하는 Mycobacterium 있어 새로운 배지와 기존의 배지에서 검출 시간의 차이는 새로운 배지가 더 빠르다는 것을 확인시켜 주었다. M. kansasii와 M. intracelluare는 7H11 배지보다 7H11 C 배지에서 더 빠르게 자라는 것으로 확인되었다. MTB는 7H11 C 배지에서 다른 배지보다 빠르게 성장하였다. 이 연구는 2 두 가지 성장 인자가 빠르게 성장하는 Mycobacteria과 느리게 성장하는 Mycobacteria에 영향을 주는 것으로 확인되었다. 7H11 C 배지는 색상 대비로 인하여 10종의 모든 Mycobacterium에서 기존배지보다 더 뛰어난 판독 용이성을 보여 주었다. 특히, MTB가 성장했을 경우 집락의 크기가 다른 배지에서 보다 커서 시각화가 용이하였다. Mycobacteria grow slowly. Therefore, a solid medium should be used for eight weeks and a liquid medium for six weeks. The purpose of this study was to find the growth factors that can grow Mycobacterium rapidly and to help develop a solid medium for rapid identification. Three types of Mycobacterium growth factors were evaluated with 10 Mycobacteria by adding activated charcoal, defibrinated sheep blood, and L-ascorbic acid to $Difco^{TM}$ Mycobacteria 7H11 agar (Becton, Dickinson and Company, Sparks, MD, USA). The time to detection and the distinguishability of a colony were compared with that of the current method. In the rapidly growing Mycobacterium, the difference in detection time between the new media and conventional media confirmed that the new media was faster. M. kansasii and M. intracelluare grew faster in 7H11 C than in 7H11 medium. MTB grew faster than the other media in 7H11 C. This study confirmed that the two growth factors affect fast-growing Mycobacteria and slow-growing Mycobacteria. 7H11 C showed better distinguishability than the conventional media in all 10 Mycobacterium due to the color contrast. In particular, when the MTB was grown, the size of the colonies was larger than with other media, so visualization was easy.

자발성 뇌내혈종환자의 치료에서 뇌정위 수술의 역할

하성일,이종수,이승재,박효일 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.2

Computerized tomography(CT) have been available for diagnosis and localization of intracerebral hematoma. CT-guided stereotactic evacuation of spontaneous intracerebral hematoma was performed in 34 cases : 25 basal ganglionic hematomas with or without ventricular perforation, 4 subcortical, 3 thalamic, 1 cerebellar and 1 pontine. The biplane CT image were taken to determine the coordinates of the target point, which was the center of the hematoma. The liquefied or solid portion of the hematoma was aspirated though a burr-hole under local anesthesia. And a silastic tube(3.3㎜ in outer diameter and 2.0㎜ in inner diameter) was then inserted into the center of the hematoma. Immediately after the first trial of hematoma aspiration, urokinase(6000 IU/5㎖ saline) was administered through the tube. Subsequently, aspiration and infusion of urokinase were repeated every 6 or 12 hours until the hematoma was almost completely evacuated. The follow-up results indicate that this procedure was more superior over the conventional craniotomy. This CT-guided stereotactic operation has the following advantages: 1) the procedure is simple and safe : 2) the procedure can be performed under local anesthesia: and 3) the hematoma can be completely drained with the aid of urokinase. This procedure can be used as standard treatment for intracerebral hematoma. We have draw the following conclusions : As a result of the above study. 1) Stereotactic surgery is more effective in the patients with neurologic grade 3 than conservative one(P<0.05). 2) To use of urokinase or perform the early surgery within 24 hours did not seem to be the cause of rebleeding. 3) In the case of pons or cerebellar hemorrhage, stereotactic surgery had definite benefit in the recovery of consciousness even if recovery of motor function was dismal. 4) In patients with spontaneous ICH, the favorable prognostic indicatiors were as follows : the size of hematoma less than 50㎖, no signs of transtentorial herniation and patient's age under 60.

순환기 : Klebsiella pneumonia에서 합병된 정맥 혈전증 1예 보고 (초)

하성일,양준승,한정연,이재광,장재혁,서영욱,정중화,고영엽,장경식,홍순표 대한내과학회 2008 대한내과학회 추계학술대회 Vol.2008 No.-

포스터 전시 발표 순서 : 순환기 ; Klebsiella pneumonia에서 합병된 정맥 혈전증 1례 보고 (초)

하성일,양준승,한정연,이재광,장재혁,서영욱,정중화,고영엽,장경식,홍순표 대한내과학회 2008 대한내과학회지 Vol.75 No.1S

CLSI M40-A2 기준에 따른 수송배지의 흡수 및 배출, 생존 효율, 회수율 평가

하성일,석현수,신정섭,허웅,박강균,박연준,Ha, Sung-Il,Suk, Hyun-Soo,Shin, Jeong-Seob,Heo, Woong,Park, Kang-Gyun,Park, Yeon-Joon 대한임상검사과학회 2019 대한임상검사과학회지(KJCLS) Vol.51 No.2

5종류의 수송배지를 흡수 및 배출 능력, 생존 효율, 회수율을 CLSI (Clinical and Laboratory Standards Institute) M40-A2의 Swab elution method (Quantitative) 기준으로 평가하였다. 액체배지가 반유동 배지보다 3가지 평가에서 대부분 우수한 결과값을 보여주었다. Flocked swab이 standard swab 형태보다 균의 흡수 및 배출의 능력 또한 우수하였다. 생존 효율에 대한 평가 결과는 액체배지(S4)가 가장 우수한 결과값을 보였다. 성장이 좋지 않은 S. pneumoniae는 액체배지(S4, S5)에서 생존효율과 회수율이 높았다. 균 회수율 평가 결과는 S. pyogenes는 모든 배지에서 CLSI 기준에 적합하였다. S. pneumoniae는 반유동 배지(S2, S3)에서 부적합하였고, 나머지 배지는 모두 기준에 적합하였다. H. influenzae는 반유동 배지(S1, S3)에서 부적합하였고, 반유동 배지(S2), 액체배지(S4, S5)에서 기준에 적합하였다. 호흡기 질환을 유발하는 S. pneumonia, H. influenzae의 생존 능력은 대부분의 배지에서 좋지 않았다. P. aeruginosa는 실온에서 과성장이 관찰되었다. 액체배지와 flocked swab의 조합이 3가지 평가 방법에서 가장 뛰어난 결과를 평가를 통해 확인하였다. The absorption and release capacities, survival efficiency, and recovery rates of five kinds of transport media were evaluated based on the swab elution method (Quantitative) of CLSI (Clinical and Laboratory Standards Institute) M40-A2. Liquid media showed mostly better results than semi-solid media in the three evaluations. The flocked swabs had better ability to absorption and discharge bacteria than the standard swabs. The liquid medium (S4) had the best survival efficiency. Pneumococcal strains with poor growth had a higher survival efficiency and recovery rate in liquid media (S4, S5). The results of microbial recovery showed that S. pyogenes met all the CLSI standards in all media. S. pneumoniae was inadequate in the semi- solid media (S2, S3) and all the remaining media met the criteria. H. influenzae was unsuitable in semi-solid media (S1, S3) and met the criteria in semi-solid medium (S2) and liquid medium (S4, S5). The viability of the H. influenzae, pneumococcal strain causing respiratory disease, was poor in most media. Overgrowth of P. aeruginosa was observed at room temperature. The combination of liquid medium and flocked swab confirmed the best results in the three evaluation methods.

렙토스피라증으로 오인된 전신홍반루푸스

하성일,이재광,김상현,김동민 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.3

Systemic Lupus Erythematosus (SLE) is autoimmune disorder involving systemic organs and charactehzed commonly by fatigue, fever, myalgia, and arthralgia. Leptospirosis is a kind of K-orean hemorrhagic fever disease and characterized commonly from fever, headache, myalgia severly to jaundice, renal failure, and hemorrhage. A 60-year-o1d woman was presented with febrile sense, myalgia, headache and general weakness, Initially, she was diagnosed as leptospirosis by serological test. Duhng treatment her clinical manifestation was not improved. On followed laboratory data, FANA positive with leukocytopenia and hemolytic anemia. Also anti-cardiolipin antibody, anti-dsDNA antibody and proteinuna was found. The serological titer of leptospirosis was not increased by four times. So, we coneluded that she had SLE and prescribed steroids. After that, her clinical manifestations were improved. Therefore, we report here on a case of SLE misdiagnosed as leptospirosis. 루푸스는 전신을 침범하는 질환으로 특히 임상 증상이 비특이적일 경우에 여러 다른 감염성 질환들로 오인될 수 있으며, 그에 따라 진다닝 늦어질수록 치료시작 시점도 늦어지게 되며, 치료 시기를 놓치게 되면 환자의 예후는 불량해진다. 본 증례는 렙토스피라증으로 입원한 환자에서 고식적인 항생제 치료를 하였으나 호전을 보이지 않았으며 임상 경과 과정중 시행한 자가면역 혈청 검사상 루푸스가 진단된 경우였다. 이에 렙토스피라증으로 오인된 루푸스 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

순환기 : 다발성 동맥색전증이 동반된 급성 ST분절상승 심근경색 1예 보고 (초)

하성일,양준승,한정연,최동현,정중화,장경식,홍순표,고영엽 대한내과학회 2010 대한내과학회 추계학술대회 Vol.2010 No.-