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혈소판 감소증 환자에서 대마비와 전신 상태의 급격한 악화 : 급성 대동맥 혈전증 A Case Report of Acute Aortic Thrombosis 증례 보고
이홍기,박훤겸,백홍규,남영수,김영선,김용수 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.2
Acute aortic occlusion is rare but poses a high mortality and morbidity. Prompt diagnosis and treatment is essential. Typical presentation is rest pain with bilateral absent femoral pulse. When the non-typical symptoms predominate such as paraplegia, acute abdomen or sudden-onset hypertension, diagnosis may be difficult. We experienced a case of acute aortic thrombosis who suddenly developed paraplegia and rapidly deteriorated within several hours. When the paraplegia developed, he was under treatment with heparin and urokinase, was thrombocytopenic, and the femoral arteries were pulsatile. Spinal cord compression due to bleeding complication had to be ruled out. Duplex sonography and lumbar CT scan were not diagnostic. Aortic thrombosis was diagnosed by abdominal CT scan. This case illustrates the need for high suspicion of acute aortic occlusion presenting with paraplegia especially in patients with associated atherosclerotic disease.
( Yong-woo Shin ),( Deok Bum Park ),( Myung-min Choi ),( Jeong-hoon Chun ),( Baik-lin Seong ),( Gi-eun Rhie ) 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.3
Molecular imaging is a powerful method for tracking various infectious disease-causing pathogens in host organisms. Currently, a dual molecular imaging method that can provide temporal and spatial information on infected hosts at the organism, organ, tissue, and cellular levels simultaneously has not been reported for Burkholderia pseudomallei, a high-risk pathogen that causes melioidosis. In this study, we have established an experimental method that provides spatiotemporal information on infected hosts using luminescent and fluorescent dual-labeled B. pseudomallei. Using this method, we visualized B. pseudomallei infection at the organism, organ, and tissue levels in a BALB/c mouse model by detecting its luminescence and fluorescence. The infection of B. pseudomallei at the cellular level was also visualized by its emitted fluorescence in infected macrophage cells. This method could be an extremely useful and applicable tool to study the pathogenesis of B. pseudomallei-related infectious diseases.
Side-Coupled Asymmetric Plastic Optical Fiber Coupler for Optical Sensor Systems
Kwang Taek Kim,Deok Gi Kim,Woong Keun Hyun,Ki Bum Hong,임기건,Se-Jong Baik,Dae-kyong Kim,Hyun-yong Choi 한국광학회 2008 Current Optics and Photonics Vol.12 No.4
This paper reports a side-coupled asymmetric 1×2 plastic optical fiber coupler for an optical sensor system. The dependence of the optical power coupling ratio on the coupling angle and refractive index of the adhesion layer in both the forward and backward directions was examined based on the geometrical optics. It was confirmed experimentally that the coupling ratios can be optimized by controlling the coupling angle and refractive index of the adhesion layer. A maximum forward coupling efficiency > 93% was achieved.
Polymyositis of the Sternocleidomastoid Muscle-A Case Report-
Jang,Se-Jin,Park,Yong-Wook,Lee,Hong Gi,Park,Hwon-Kyum,Nam,Young-Soo,Baik,Hong-Kyu 한양대학교 의과대학 1997 한양의대 학술지 Vol.17 No.2
다발성 근육염은 두경부의 한개 또는 여러개의 근육에 단단한 종괴로서 발현되는 양성 염증성 질환이며, 이는 교원성혈관질환 또는 자가면역질환으로 분류되기도 한다. 이 질환의 원인은 아직 정확히 발견되지는 않았으나 매우 드문 질환으로 다른 두경부의 종양과 감별진단이 중요하다. 이 질환은 일반의 염증성 종괴와 달라서 항생제치료에 효과가 없으며 스테로이드나 면역억제제의 치료에 반응하나 자연치유되지는 않는다. 저자는 우측 경부의 흉쇄유양돌기성 근육에 발생한 다발성 근육염환자 일 예를 경험하여 조직검사와 치료과정의 경과로서 확진하여 문헌고찰과 함께 보고하는 바이다.
근치적 위절제술을 시행한 위암 환자에서 보조요법으로서 5-Fluorouracil, Epirubicin과 5-Epirubicil,Cisplatin의 복합화학요법의 효과 비교
최정혜,안명주,한동수,손주현,전용철,박훤겸,백홍규,이홍기,남영수 한양대학교 의과대학 2000 한양의대 학술지 Vol.20 No.2
To compare 5-fluorouracil plus epirubicin (FE) to 5-fluorouracil plus cisplatin (FP) chemotherapy as adjuvant therapy for patients with resected gastric cancer. Between August 1995 and March 2000, 46 patients with completely resected gastric cancer received six courses of FE (5-fluorouracil 1000mg/m2/day, D2-D5, epirubicin 70mg/m2, D1) or FP (5-fluorouracil 1000mg/m2/day, D2-D5, cisplatin 70mg/m2, D1) chemotherapy. The 23 patients were assigned to each treatment group. A total of 127 courses of treatment were given both FE and FP group. The FP group tended to show more risk of overall death rate. But there were no differences between FE and FP groups in terms of overall survival or disease-free survival. Both treatment arms were generally well tolerated to chemotherapy. We concluded to be no significant differences between FE and FP groups in terms of overall survival or disease-free survival. To define the efficacy of adjuvant chemotherapy for gastric adenocarcinoma, further prospective randomized trials with large number of patients should be warranted.