OB-63 : Positive effects of Teratogenic risk counseling in pregnant women inadvertently exposed to medications

( Hyo Yeon Gwak ),( Jung Eun Lee ),( Ju Young Choi ),( So Yeon Kim ),( Song Mi Park ),( June Seek Choi1,),( Hyun Kyong Ahn ),( Min Hyung Kim ),( Jin Hoon Chung ),( Moon Young Kim ),( Hyun Mee Ryu ),( 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: To evaluate the positive effects of teratogenic risk counseling in pregnant women inadvertently exposed to medication in early pregnancy. 방법: In a prospective cohort study, 250 pregnant women exposed to medications in early pregnancy were recruited after teratogenic risk counseling at Korean MotherSafe Counsling Center, which has given information about teratogenic risk of medication to pregnant women. Positive effects are evaluated by visual analogue scale(VAS) for perception on teratogenic risk and percent prefering termination of pregnancy after medication exposures in pregnancy. 결과: Mean age of participants is 31.8±5.3years old. Mean gravidity is 2.4±2.1. Medications exposed in early pregnancy include antibiotics, analgesics, anti-inflammatory drugs, antacid and so on. Mean perceptive teratogen risk before and after the counseling is 33.9±1.6% and 15.8±1.6%, respectively. And mean percent prefering termination of pregnancy (≥5) before and after the counseling is 31.1±1.9% and 13.5±1.7%, respectively. 결론: Our data suggest that information on teratogenic risk for pregnant women inadvertently exposed to medication may have positive effects for reassuring pregnant women and preventing termination of pregnancy.

Inoue Balloon을 이용한 PMV의 장·단기 결과 분석

진은선,이연아,전숙,김현숙,정승묵,박상선,최락경,임달수,홍석근,황흥곤 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.11

저수축형 폴리머 콘크리트의 제조 및 물리·역학적 특성

연규석,이윤수,최동순,정경현,황진하 강원대학교 부설 석재복합신소재 제품연구센터 2000 석재연 논문집 Vol.5 No.-

본 연구에서는 폴리머 콘크리트의 수축저감을 목적으로 수지량, 수축저감제함량과 S/a 비등을 변화시켜 경화수축의 변화와 강도 특성을 실험적으로 구명하였다. 경화수축량은 수치량이 105%일 때 보다 11.5%일 때, 즉 수지량이 증가할수록 커짐을 알 수 있었다. 수축저감제의 첨가에 따른 경화수축량은 감소함을 알 수 있었다. B10.5-SR10일 경우 수축저감제가 첨가되지 않았을 때 보다 약 30%, B10.5-SR20 일 경우 약 53%, B11.5-SR10일 경우 약 31%, B11.5-SR20 일 경우 약 47% 정도의 수축저감의 효과를 볼 수 있었다. S/a 비에 따른 경화 수축챨ㅇ은 S/a 60일 때 가장 적은 값을 보였으며, S/a 50, S/a 40 일때는 S/a60 일 때 가장 적은 값을 보였으며, S/a 50, S/a 40일 때는 S/a 60일 때 보다 각각 10%, 30% 정도 수축량이 증가함을 알 수 있었다. 압축 및 휨 강도특성은 수지량이 증가할수록 높아지고, 수축저감제의 첨가량이 증가할수록 낮아짐을 알 수 있었다. S/a 비에 따른 강도 특성은 압축강도와 휨강도 모두 S/a 비가 60일 때 가장 큰 값을 보였으며, S/a 비가 50,40 순으로 감소하였다. Many different polymer based concrete materials are known today, but the large setting or hardening shrinkage of polymer concrete is a problem to overcome in their practical applications. The setting shrinkage reaches about five to ten times the drying shrinkage of ordinary cement concrete, i.e, 50 to 60 ×10^4. This paper deals with a reduction in the hardening shrinkage of unsaturated polyester resin concrete which is treated with respect to shrinkage-reducing agent content, S/a ratio and catalyst content, and tested for length change during hardening, and flexural and compressive strengths. It is shown that the change of shrinkage-reducing agent content and S/a ration the length change of the unsaturated polyester resin concrete during hardening.

小兒期 精神分裂症 : 思春期 以前 發病群과 思春期 以後 發病群의 臨床的 比較 硏究 A Comparison between the Two Groups with the onset prior to Puberty and after Puber

崔珍淑,鄭嬉然,崔貞美,曺洙哲,洪剛義 서울醫大 1991 精神醫學 Vol.16 No.4

冬蟲夏草의 抗轉移와 免疫增進에 關한 硏究

최우진,유화승,이용연,서상훈,조정효,이연월,손창규,조종관 대전대학교 한방병원 2000 惠和醫學 Vol.9 No.2

This experimental study was carried out to evaluate the effects of Cordiceps sinensis on the antimetastasis and immune activity. In order to investigate the effect of Cordiceps sinensis, the followings were performed; Cytotoxicity, inhibition of MMP-2 & MMP-9 gene expression, fraction of CD4+, CD8+, CD19+ in splenic cell, the moprphological change of splenic cells, gene expression of IL-12(p35), IL-12(p40), IFN-?? and splenic cell proliferation by CS-E. The results were obtained as follows. 1. CS-E did not present cytotoxic effect on L+14, B16-F10 melanoma cells and HMCB. 2. CS-E inhibited MMP-2 and MMP-9 gene expression more effectively compared with control group. 3. CS-E inhibited invasion of B16-F10 melanoma cells more effectively compared with control group. 4. CS-E helped CD4+, CD8+, CD19+ expression more effectively compared with control group. 5. CS-E activated phagocytic cells in spleen more effectively compared with control group. 6. CS-E helped IL-12(p35), IL-12(p40), IFN-?? gene expression in splenic cell more effectively compared with control group. 7. CS-E activated splenic cell proliferation more effectively compared with control group. From above findings, it is suggested that CS-E is able to inhibit metastasis of cancer and activate immune response system.

임부의 연령에 따른 보완대체요법에 관한 인식 태도 경험 비교 연구

김연진,김지연,노경민,신혜리,유예지,이지민,장희조,정아인,최소정,강숙정,이향연,민혜영 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50

Purpose: This study aims to test if the age of pregnant women affects the perception, experience, and attitude towards complementary alternative therapy (CAT), by investigating the perception, experience, and attitude of pregnant women under the age of 35, and above 35 (Advanced Maternal Age). The study will 1) find the general characteristics of pregnant women under and over the age of 35 2) compare the perception, behavior, and experience of pregnant women under and over the age of 35, and 3) find the comparison of the perception, behavior, and experience according to the general characteristics of pregnant women under and over the age of 35. Method: The subjects of this study are composed of 44 women under the age of 35 and 44 women above the age of 35, totaling 88 pregnant women visiting midwiferies, obstetrics and gynecology, and baby fairs in Seoul and Gyeong-Gi area. Data for this study was collected from November 28, 2015 to January 6, 2016 for 40 days. The collected data analyzed mean, standard deviation, t test, ANOVA, and chi-square by using SPSS 23.0. Result Results show that there is a significant difference in the perception, attitude, and experience of the two-sample groups in the use of CAT. The question of “what is most necessary when applying CAT in a hospital clinical environment” for the perception criteria came out with the results of t=9.980, p<.05. For the attitude, results showed that the answers of pregnant women under the age of 35 displayed a more positive attitude towards CAT. (t=2.421, p<.05) Lastly, in the experience section, pregnant women under the age of 35 showed more CAT use than the other sample group. Conclusion Results have shown that there is a difference in the perception, behavior, and experience between the two sample groups. Therefore further research on the efficacy and the adverse effects of CAT needs to be done.

Starter 및 멸치액젓 첨가가 김치양념 및 겉절이 김치의 품질에 미치는 영향

최택권,박소희,유진현,임호수,조재선,황성연 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.2

양념에 Leu. mesenteroides, Lac plantarum의 젖산균과 멸치액젓 첨가가 김치 양념의 대장균군 제어, 속성촉진여부 및 관능적 특성에 미치는 영향을 조사하였다. Leu. mesenteroides과 젓갈을 첨가한 경우 초기 숙성이 촉진되나 후기 산패는 완만하였으며 Lac. plantarum의 첨가시에는 초기 숙성에는 큰 차이가 없고 후기 산패가 현저하게 진행되었다. 대장균군은 산도 0.80% 이상에서 사멸되었는데 leu. mesenteroides의 경우가 숙성이 촉진되어 보다 신속히 사멸시켰다. 총균수와 젖산균수는 초기에 starter 첨가구는 10^6CFU/mL 정도인데 반해서 starter를 첨가하지 않은 않은 처리구에서 총균수는 10^6CFU/mL , 젖산균수가 10^4CFU/mL 이었고 숙성 후에는 첨가균이 높은 수준을 유지하였다. 하지만 대체적으로 스타터의 첨가가 숙성 및 대장균에 크게 영향을 주지 못하는 경향으로 동일하게 나왔다. 관능적 특성에서는 Leu. mesenteroides 첨가구가 Lac. plantarum의 경우보다 우수하였다. 한편, 시판 겉절이 김치는 산도가 0.09~0.18%, ph 5.46~5.89, 총균수 2.2×10^6~3.1×10^7CFU/mL, 젖산균수는 2.1×10^4~6.6×10^5CFU/mL, 대장균수는 1.8×10^4~7.1×10^5CFU/mL, 염분 1.89%~2.51%으로 스타터 첨가 겉절이에 비해 ph와 염도를 제외한 품질 특성에서 전반적으로 낮은 값을 나타냈다. This study was performed in order to investigate the effect of Leuconostoc mesenteroides, Lactobacillus plantarum and salt fermented anchovy extracts on Kimchi sauce. The sauce was fermented more rapidly by addition of Leu. mesenteroids or salt fermented anchovy extracts on the early fermentation stage than the control, but it was fermented slowly on the late fermentation stage. When L. plantarum was added to the Kimchi on the early fermentation stage, the acidity of Kimchi didn't show a significant difference from the control, but acidity was remarkably increased on the late stage. Coliform group was disappeared when acidity of sauce was higher than 0.8% during fermentation. It was controlled by Leu. mesenteroides but not by L. plantarum. Total count and lactic acid bacterial count of the sauces with starter were 6.30×10^6~1.0×10^7 CFU/mL and 1.04~2.04×10^6 CFU/mL, respectively, but those of the control sauce were 10^6 CFU/mL and 10^4 CFU/mL, respectively. Those count of the sauce with starter were higher than those of the control sauce on the later stage of fermentation. Organoleptic quality of the sauce with Leu. mesenteroides was superior to that with L. plantarum.

호텔 고객의 뷔페 메뉴품질 만족도에 관한 연구

최수근,이연정,이진형 한국식생활문화학회 2004 韓國食生活文化學會誌 Vol.19 No.5

This study aims at providing useful information to establish subdivided marketing direction by deriving factors of significant extent and practicable extent of buffet users toward menu quality among super deluxe hotels in Gyeongju, and furthermore aims at presenting implications for efficient management result and sales increase of buffet in the future. The result of positive analysis is as follows. Firstly, in result of analyzing difference between importance and performance of hotel buffet in Gyungju area, importance is much higher than performance. Secondly, respondents consider that the. most important menu of hotel buffet is main dish such as hot food and instant food rather than menu such as beverage, soup and salad. When it comes to attribute of menu quality, it appeared that respondents put highly significant extent on sanitariness of food, freshness of food, flavor of food, and seasonality and variety of menu. Thirdly, oriental instant food is included in the second quadrant of IPA regarding buffet menu which should be intensively managed. And three attributes such as temperature of food, time of changing food, and creativity of menu are included in the second quadrant of IPA graph by attribute of hotel buffet's menu quality. Lastly, in IPA graph by hotel, the following menus of each hotel need to be intensively managed: Oriental instant food of A hotel, Western cold food of B hotel, Oriental instant food, Western instant food, and Oriental dessert of C hotel, and Western porridge·soup, Oriental instant food, and Western instant food of E hotel. The aforementioned menus should be improved.

간질에 대한 임상적 고찰

최진영,유병연 건국대학교 1995 學術誌 Vol.39 No.2

Epilepsy occurs in all age groups with a variety of diseases that alter neuronal function in a specific way. In spite of the development in diagnosis and treatment of epilepsy, epileptic patients were treated inappropriately and are often handicapped by the psychosocial consequence of their conditions, The purpose of this study is to provide reference and education to patients and their families. Clinical study via chart review was carried out on 110 patients with seizure who visited outpatient department of neurology and were consulted from other departments, Kon Kuk University Hospital from July, 1990 to August, 1993. The results were as follows : Males were more affected than females in the ratio of 1.89 :1. In their distribution of age, teens were most frequent(38.18%). seizure occured most frequently in the first decade(35.45%). The seizure types were : generalized seizure 86.36%(tonic-clonic 74.54%, tonic 8.18%, clonic 1.82%, atonic0.19%, atypical absence 0.91%) : Partial seizure 13.63%(complex partial 7.27%, secondary generalized6.37%). Causes of seizure were idiopathic(58.18%), trauma(13.63%), developmental(8.18%), cerebrovascular disease(7.27%), etc. The major part of all idiopathic cases had their attack of seizure before 30 years of age and those of symptomatic cases were rather late over age of 30. On EEG, abnormal findings were noted in 66.99%. Abnormal EEG findings were found more commonly in complex partial seizure(71.43%) than generalized seizure(66.67%) and secondary generalized seizure(66.67%). On brain CT scan, abnormal findings were noted 52.94%, and the abnormal findings were found more commonly in complex partial seizure(66.77%) than generalized seizure(54.54%) and secondary generalized seizure(25%). Abnormal brain CT scan findings were noted in 46.67% of normal EEG patients and in 51.52% of abnormal EEG patients. Most frequently used antiepileptic drug was carbamazepine. The serum level of antiepileptic drugs was in therapeutic ranges and clinical effect was good. Epileptic patients can perform daily activities without any handicap if they are properly treated. We should educate the community against the miss-belief about epilepsy.

골반염증성 질환과 질염을 가진 환자의 진단과 추적관찰에서 Chlamydia trachomatis의 검출을 위한 이중 중합효소 연쇄반응의 적용

이진우,조현철,최규연,배동한,김휘준 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Objectives : PCR has generally been more sensitive than the conventional microbiological test for the detection of C.trachomatis which has been a leading cause of sexually transmitted disease. The purpose of this study was to evaluate the prevalence of C.trachomatis infection in the patients with pelvic imflammatory disease(PID) and the usefulness of nested PCR as a follow-up test in patiens with C. trachomatis infection after administration of antibiotics. Methods: Cervical swab specimens were obtained from 187 patients with PID and vaginitis attending the Soonchunhyang Chunan Hospital. From the C. trachomatis positive patients, cervical swab specimens were obtained once a week after treatment until PCR tested negative. We performed the nested PCR with Chlamydia-CR kit(Bioneer, Korea.) Results: From 6(5.8%) of 187 cervical swab specimen, C. Trachomatis was detected by nested PCR. These patients were treated with doxycycline and metronidazole for 7 to 14 days. All of 6 C. trachomatis positive patients revealed PCR-negative immediately after the completion of antibiotics treatment. Conclusions: With the above results, the nested PCR is a relatively simple, fast, and practical tool for the detection of C. trachmatis and may be a useful follow-up test for monitoring the treatment effect.