Study on Crack Resistance and Calculation Model of RAC Beams Strengthened with Prestressed CFRP

Yanting Ji,Sheng Sun,Aijiu Chen,Fen Yang,Shihua Bai,Xiaoyan Han 한국콘크리트학회 2024 International Journal of Concrete Structures and M Vol.18 No.2

With the development of recycled aggregate concrete (RAC), the recovery rate of construction waste is improved, and the pollution problem is alleviated. In particular, RAC beams strengthened with prestressed carbon fiber reinforced plastics (CFRP) can exhibit improved mechanical properties, expanding RAC application. Four groups of reinforced RAC beam specimens contained 0%, 40%, 70%, and 100% recycled coarse aggregate, respectively. Each group of beams was first pre-cracked and then strengthened by prestressed CFRP with one layer and two layers respectively. Finally, the bearing capacity tests were performed for these beams. The test results show that as the recycled coarse aggregate content increases, the cracking moment and ultimate load capacity of the beam decrease, while its crack width increases. As the CFRP layer increases, the deformation and crack width of the beam decreases, while the number of cracks increases. The prestressed CFRP also exhibited tensile and peeling failure. A beam deflection calculation model was established by introducing a coefficient k representing the interaction between recycled aggregate and CFRP. The influence coefficient of concrete elongation on the crack width and average crack spacing of the beam was modified, and the crack width analysis model of the beam was established. The calculated results are in good agreement with the experimental observations. It can provide reference for the application and design of recycled concrete beams strengthened with prestressed CFRP.

Double-Loop Coil Design for Wireless Power Transfer to Embedded Sensors on Spindles

Chen, Suiyu,Yang, Yongmin,Luo, Yanting The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2

The major drawbacks of magnetic resonant coupled wireless power transfer (WPT) to the embedded sensors on spindles are transmission instability and low efficiency of the transmission. This paper proposes a novel double-loop coil design for wirelessly charging embedded sensors. Theoretical and finite-element analyses show that the proposed coil has good transmission performance. In addition, the power transmission capability of the double-loop coil can be improved by reducing the radius difference and width difference of the transmitter and receiver. It has been demonstrated by analysis and practical experiments that a magnetic resonant coupled WPT system using the double-loop coil can provide a stable and efficient power transmission to embedded sensors.

A trigonometric series expansion based method for the research of static and dynamic characteristics of eccentric seals

Dan Sun,Jian Gang Yang,Rui Guo,Wan Fu Zhang,Yanting Ai 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.6

Static and dynamic characteristics of labyrinth seals are important in the prediction of the stability of turbomachinery. The paper presentsan effective numerical method to predict the static and dynamic performance characteristics of seals at off-center conditions withdifferent rotor whirling frequency. Modifications are introduced for the traditional turbulent bulk flow model to consider the circumferentiallyvarying flow. A trigonometric series expansion method is used to approximate parameters such as pressure and velocity in sealscavity. Numerical simulations show that 8-10 series terms with 5-10 iterations are enough for the solution of this set of nonlinear equations. The resulting nonlinear algebraic equations can be solved rapidly. The analytical results are verified by comparison with the simulatedCFD results. Parametric investigations showing the influence of eccentricity and whirling frequency on seals dynamics are alsopresented. The results show that the trigonometric series expansion based method gives an effective prediction of the static and dynamiccharacteristics of the eccentric seals.

Double-Loop Coil Design for Wireless Power Transfer to Embedded Sensors on Spindles

Suiyu Chen,Yongmin Yang,Yanting Luo 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.2

The major drawbacks of magnetic resonant coupled wireless power transfer (WPT) to the embedded sensors on spindles are transmission instability and low efficiency of the transmission. This paper proposes a novel double-loop coil design for wirelessly charging embedded sensors. Theoretical and finite-element analyses show that the proposed coil has good transmission performance. In addition, the power transmission capability of the double-loop coil can be improved by reducing the radius difference and width difference of the transmitter and receiver. It has been demonstrated by analysis and practical experiments that a magnetic resonant coupled WPT system using the double-loop coil can provide a stable and efficient power transmission to embedded sensors.

In Vitro and In Vivo Study on the Effect of Lysosome-associated Protein Transmembrane 4 Beta on the Progression of Breast Cancer

Deyou Tao,Junqing Liang,Yihong Pan,Yanting Zhou,Ying Feng,Lin Zhang,Jingjing Xu,Hui Wang,Ping He,Jie Yao,Yang Zhao,Qinjie Ning,Wen Wang,Wei Jiang,Jing Zheng,Xia Wu 한국유방암학회 2019 Journal of breast cancer Vol.22 No.3

Purpose: Although the effect of lysosome-associated protein transmembrane 4 beta (LAPTM4B) on the proliferation, migration, and invasion of breast cancer (BC) cells has already been studied, its specific role in BC progression is still elusive. Here, we evaluated the effect of different levels of LAPTM4B expression on the proliferation, invasion, adhesion, and tumor formation abilities of BC cells in vitro, as well as on breast tumor progression in vivo. Methods: We investigated the influence of LAPTM4B expression on MCF-7 cell proliferation, invasion, adhesion, and tube formation abilities in vitro through its overexpression or knockdown and on breast tumor progression in vivo. Results: Cell growth curves and colony formation assays showed that LAPTM4B promoted the proliferation of breast tumor cells. Cell cycle analysis results revealed that LAPTM4B promoted the entry of cells from the G1 into the S phase. Transwell invasion and cell extracellular matrix adhesion assays showed that LAPTM4B overexpression increased the invasion and adhesion capabilities of MCF-7 cells. More branches were observed in MCF-7 cells overexpressing LAPTM4B under an electron microscope. In comparison with LAPTM4B overexpression, LAPTM4B knockdown decreased the expression of vascular endothelial growth factor-A and significantly inhibited the vasculogenic tube formation ability of tumors. These results were also verified with western blot analysis. Conclusion: LAPTM4B promoted the proliferation of MCF-7 cells through the downregulation of p21 (WAF1/CIP1) and caspase-3, and induced cell invasion, adhesion, and angiogenesis through the upregulation of hypoxia-inducible factor 1 alpha, matrix metalloproteinase 2 (MMP2), and MMP9 expression. This specific role deems LAPTM4B as a potential therapeutic target for BC treatment.

깊은 신경망 훈련 및 규제 기법을 이용한 요추 환자의 CT 영상에서 요추 분할

장민혜(Min Hye Chang),양정원(Jeongwon Yang),차보경(Bo Kyung Cha),김진성(Jin-Sung Kim),김은(Eun Kim),Yanting Liu,이경희(Kyeong-Hee Lee) 대한전자공학회 2021 대한전자공학회 학술대회 Vol.2021 No.6

In this paper, DNN training and regularization techniques have been explored for lumbar vertebrae segmentation in CT images of patients with degenerative lumbar spine disease. Combinations of loss function, learning rate schedule, normalization, dropout, moving average, weight decay, and squeeze-and-excitation were empirically tested. The results confirmed that the DNN with optimized training and regularization techniques can improve lumbar vertebrae segmentation without complex structural changes.

Metal-Doped In2O3 Nanosphere Arrays with Enhanced Gas-Sensing Property

Xuanji Zhang,Ni Deng,Xianjia Chen,Yanting Yang,Jing Li,BO HONG,DINGFENG JIN,Xiaoling Peng,XINQING WANG,Hongliang Ge,HONGXIAO JIN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.3

In2O3 and metal-doped (Ni or Ce) In2O3 mesoporous three-dimensional (3D) nanospheres arrays were synthesized via nanocasting using mesoporous silica as hard templates. Effects of Ni or Ce doping on the structure, optical and gas-sensing properties of the In2O3 nanospheres were investigated. Both the undoped and the doped In2O3 nanospheres showed single-phase structure without any impurity. The nanospheres were about 20 nm in size and they stacked closely to formrigid 3D mesoporous structure. Achange in the value of optical band gap was observed upon metal doping. The room temperature photo luminescence behavior also showed some differences between pure and doped In2O3. Compared with pure In2O3 nanospheres, the metal-doped In2O3 exhibited superior response, fast recovery and good selectivity to ethanol. The enhanced gas-sensing properties might be related to the doping of metal ion and its effective contribution towards the oxygen vacancies, conductivity and crystallite size of the grains.

Two kinds of behavior of fruit peel coagulant in treating low carbon source wastewaters

Ying Fu,Qinghe Yue,Shuyuan Luo,Xi Tian,Jiewen Zheng,Yanting Yang 대한환경공학회 2023 Environmental Engineering Research Vol.28 No.4

Based on present serious phenomenon of insufficient carbon source in municipal sewage in China, the two kinds of effect of hybrid-fruit-peel (HFP) coagulant (coagulation and external carbon source (ECS)) on treating low carbon source wastewater was studied, mainly compared with that of sodium acetate (NaAc). The feasibility of HFP as an ECS was researched, and then its coagulation behavior, sludge properties, nitrogen removal were studied mainly with aeration mode and sequencing batch reactor (SBR), respectively. The results showed the ration of biochemical oxygen demand (BOD5) to chemical oxygen demand (COD) released from HFP was 0.67−0.76, within the scope of easily biodegradable. Within a short aeration time, HFP posed obvious coagulation behavior. HFP sludge gave larger extracellular polymer (EPS) and lower dehydrogenase activity (DHA) than NaAc. For HFP, much larger size sludge flocs appeared, the connection among the flocs became closer, and the biofacies and number of microorganisms (Opercularia Coaractata, Nematode, Vorticella, etc.) increased significantly. HFP can be used as an excellent ECS for low carbon source wastewater, and probably also have the ability of slow-releasing carbon, and can be applied to municipal sewage or other wastewaters with insufficient carbon source.

Resveratrol Exerts Dosage-Dependent Effects on the Self-Renewal and Neural Differentiation of hUC-MSCs

Fangxia Guan,Xinxin Wang,Shanshan Ma,Nan Meng,Ning Yao,Kun Zhang,Qinghua Li,Yanting Zhang,Qu Xing,Kang Han,Jishi Song,Bo Yang 한국분자세포생물학회 2016 Molecules and cells Vol.39 No.5

Resveratrol (RES) plays a critical role in the fate of cells and longevity of animals via activation of the sirtuins1 (SIRT1) gene. In the present study, we intend to investigate whether RES could promote the self-renewal and neural-lineage differentiation in human umbilical cord derived MSCs (hUC-MSCs) in vitro at concentrations ranging from 0.1 to 10 M, and whether it exerts the effects by modulating the SIRT1 signaling. Herein, we demonstrated that RES at the concentrations of 0.1, 1 and 2.5 M could promote cell viability and proliferation, mitigate senescence and induce expression of SIRT1 and Proliferating Cell Nuclear Antigen (PCNA) while inhibit the expression of p53 and p16. However, the effects were reversed by 5 and 10 M of RES. Furthermore, RES could promote neural differentiation in a dose-dependent manner as evidenced by morphological changes and expression of neural markers (Nestin, Ⅲ-tubulin and NSE), as well as pro-neural transcription factors Neurogenin (Ngn)1, Ngn2 and Mash1. Taken together, RES exerts a dosage-dependent effect on the self-renewal and neural differentiation of hUC-MSCs via SIRT1 signaling. The current study provides a new strategy to regulate the fate of hUC-MSCs and suggests a more favorable in vitro cell culture conditions for hUC-MSCs-based therapies for some intractable neurological disorders.

Resveratrol Exerts Dosage-Dependent Effects on the Self-Renewal and Neural Differentiation of hUC-MSCs

Wang, Xinxin,Ma, Shanshan,Meng, Nan,Yao, Ning,Zhang, Kun,Li, Qinghua,Zhang, Yanting,Xing, Qu,Han, Kang,Song, Jishi,Yang, Bo,Guan, Fangxia Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.5

Resveratrol (RES) plays a critical role in the fate of cells and longevity of animals via activation of the sirtuins1 (SIRT1) gene. In the present study, we intend to investigate whether RES could promote the self-renewal and neural-lineage differentiation in human umbilical cord derived MSCs (hUC-MSCs) in vitro at concentrations ranging from 0.1 to $10{\mu}M$, and whether it exerts the effects by modulating the SIRT1 signaling. Herein, we demonstrated that RES at the concentrations of 0.1, 1 and $2.5{\mu}M$ could promote cell viability and proliferation, mitigate senescence and induce expression of SIRT1 and Proliferating Cell Nuclear Antigen (PCNA) while inhibit the expression of p53 and p16. However, the effects were reversed by 5 and $10{\mu}M$ of RES. Furthermore, RES could promote neural differentiation in a dose-dependent manner as evidenced by morphological changes and expression of neural markers (Nestin, ${\beta}III-tubulin$ and NSE), as well as pro-neural transcription factors Neurogenin (Ngn)1, Ngn2 and Mash1. Taken together, RES exerts a dosage-dependent effect on the self-renewal and neural differentiation of hUC-MSCs via SIRT1 signaling. The current study provides a new strategy to regulate the fate of hUC-MSCs and suggests a more favorable in vitro cell culture conditions for hUCMSCs-based therapies for some intractable neurological disorders.