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Atomic-Scale Spectroscopy of Gated Monolayer MoS<sub>2</sub>
Zhou, Xiaodong,Kang, Kibum,Xie, Saien,Dadgar, Ali,Monahan, Nicholas R.,Zhu, X.-Y.,Park, Jiwoong,Pasupathy, Abhay N. American Chemical Society 2016 NANO LETTERS Vol.16 No.5
<P>The electronic properties of semiconducting monolayer transition-metal dichalcogenides can be tuned by electrostatic gate potentials. Here we report gate-tunable imaging and spectroscopy of monolayer MoS<SUB>2</SUB> by atomic-resolution scanning tunneling microscopy/spectroscopy (STM/STS). Our measurements are performed on large-area samples grown by metal–organic chemical vapor deposition (MOCVD) techniques on a silicon oxide substrate. Topographic measurements of defect density indicate a sample quality comparable to single-crystal MoS<SUB>2</SUB>. From gate voltage dependent spectroscopic measurements, we determine that in-gap states exist in or near the MoS<SUB>2</SUB> film at a density of 1.3 × 10<SUP>12</SUP> eV<SUP>–1</SUP> cm<SUP>–2</SUP>. By combining the single-particle band gap measured by STS with optical measurements, we estimate an exciton binding energy of 230 meV on this substrate, in qualitative agreement with numerical simulation. Grain boundaries are observed in these polycrystalline samples, which are seen to not have strong electronic signatures in STM imaging.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2016/nalefd.2016.16.issue-5/acs.nanolett.6b00473/production/images/medium/nl-2016-004733_0003.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl6b00473'>ACS Electronic Supporting Info</A></P>
Zhou, Xiaodong,Lee, Jong Eun,Arnett, Frank C.,Xiong, Momiao,Park, Min Young,Yoo, Yeon Kyeong,Shin, Eun Soon,Reveille, John D.,Mayes, Maureen D.,Kim, Jin Hyun,Song, Ran,Choi, Ji Yong,Park, Ji Ah,Lee, Y Wiley Subscription Services, Inc., A Wiley Company 2009 Vol.60 No.12
<B>Objective</B><P>To identify systemic sclerosis (SSc) susceptibility loci via a genome-wide association study.</P><B>Methods</B><P>A genome-wide association study was performed in 137 patients with SSc and 564 controls from Korea using the Affymetrix Human SNP Array 5.0. After fine-mapping studies, the results were replicated in 1,107 SSc patients and 2,747 controls from a US Caucasian population.</P><B>Results</B><P>The single-nucleotide polymorphisms (SNPs) (rs3128930, rs7763822, rs7764491, rs3117230, and rs3128965) of HLA–DPB1 and DPB2 on chromosome 6 formed a distinctive peak with log P values for association with SSc susceptibility (P = 8.16 × 10<SUP>−13</SUP>). Subtyping analysis of HLA–DPB1 showed that DPB1*1301 (P = 7.61 × 10<SUP>−8</SUP>) and DPB1*0901 (P = 2.55 × 10<SUP>−5</SUP>) were the subtypes most susceptible to SSc in Korean subjects. In US Caucasians, 2 pairs of SNPs, rs7763822/rs7764491 and rs3117230/rs3128965, showed strong association with SSc patients who had either circulating anti–DNA topoisomerase I (P = 7.58 × 10<SUP>−17</SUP>/4.84 × 10<SUP>−16</SUP>) or anticentromere autoantibodies (P = 1.12 × 10<SUP>−3</SUP>/3.2 × 10<SUP>−5</SUP>), respectively.</P><B>Conclusion</B><P>The results of our genome-wide association study in Korean subjects indicate that the region of HLA–DPB1 and DPB2 contains the loci most susceptible to SSc in a Korean population. The confirmatory studies in US Caucasians indicate that specific SNPs of HLA–DPB1 and/or DPB2 are strongly associated with US Caucasian patients with SSc who are positive for anti–DNA topoisomerase I or anticentromere autoantibodies.</P>
Failure analysis for hoisting wire ropes with local accumulated broken wire damage on the surface
Ping Zhou,Gongbo Zhou,Lianfeng Han,Xiaodong Yan,Hanyu Wang,Zhenzhi He 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.7
Surface broken wire (BW) damage to hoisting steel wire ropes (SWR) is unavoidable during the service process, and it continues to accumulate locally during the evolution process. The specific influence analysis of the surface damage with local cumulative BWs on the performance of the hoisting SWR is insufficient at present, which seriously affects the safety of the rope system. In this paper, a failure analysis method for the state of surface cumulative BW rope based on the integration of finite element (FE) and mechanical tension is proposed. First, a method for creating an FE model of surface BW damage is presented, and the stress-strain distribution features of damaged section under tensile load are revealed. Then, the residual mechanical strength of SWR under local cumulative BW damage is determined by performing a tensile test. Finally, based on the analysis of FE and breaking behavior, combined with the regulations, the state of the damaged SWR is comprehensively evaluated. The results show that the breaking position of the SWR under mechanical tension is the maximum stress distribution in the simulation analysis, which verifies the consistency between the simulation and the experiment; and the accumulation degree and distribution of local BW affect the residual mechanical strength of the SWR. This method explores the influence of different degrees of local BW damage on the mechanical properties of the SWR, which provides a direct basis for the non-destructive evaluation of the SWR state.
Behaviors of Wall and Ground due to T-shaped Excavation
Xiaodong Zhao,Guoqing Zhou,Laijun Qiao,Yangguang Chen 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.5
Extensive monitoring was performed on a T-shaped site with a length of 280 m, a width of 16 m, and a maximal depth of 20.4 m. The braced excavation was performed under retaining comprised of cast-in-situ bored piles and jet grouting piles. The field databased wall performance and its influences to ground were assessed by detailed comparisons with that in other excavations. It is showed that the wall deflections, ground movements and bracing forces all exhibited a typical camelback-shaped characteristic along the length direction, and a maximum 100% reduction of which was observed due to the jet grouting. The rebar near sections with varied excavation depths was in a tension state both on the excavation and the retained sides due to the twodimensional unbalanced force, and the corresponding bracing force was small. The maximum wall deflection δhm decreased asthe partitioning excavation moved horizontally, and it was less than 0.04% of the final horizontal excavation length Le. The normalized Fσmax approximately approached to be identical with the normalized Fbmax, while most of the occurring depths for Fσmax were greater than that for Fbmax.
A Genetic Approach for Joint Link Scheduling and Power Control in SIC-enable Wireless Networks
( Xiaodong Wang ),( Hu Shen ),( Shaohe Lv ),( Xingming Zhou ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.4
Successive interference cancellation (SIC) is an effective means of multi-packet reception to combat interference at the physical layer. We investigate the joint optimization issue of channel access and power control for capacity maximization in SIC-enabled wireless networks. We propose a new interference model to characterize the sequential detection nature of SIC. Afterward, we formulize the joint optimization problem, prove it to be a nondeterministic polynomial-time-hard problem, and propose a novel approximation approach based on the genetic algorithm (GA). Finally, we discuss the design and parameter setting of the GA approach and validate its performance through extensive simulations.
Receiver Techniques for Ultra-wide-band Multiuser Systems over Fading Multipath Channels
Zhou, Xiaobo,Wang, Xiaodong The Korea Institute of Information and Commucation 2003 Journal of communications and networks Vol.5 No.2
We treat the problem of channel estimation and interference cancellation in multiuser ultra-wide-band (UWB) communication systems over multipath fading channels. The UWB system under consideration employs a random time-hopping impulse radio format. We develop a channel estimation method based on linear weighted algorithm. An iterative channel estimation and interference cancellation scheme is proposed to successively improve the receiver performance. We also consider systems employing multiple transmit and/or receive antennas. For systems with multiple receive antennas, we develop a diversity receiver for the wellseparated antennas. For systems with multiple transmit antennas, we propose to make use of Alamouti’s space-time transmission scheme, and develop the corresponding channel estimation and interference cancellation receiver techniques. Simulation results are provided to demonstrate the performance of various UWB receiver techniques developed in this paper.
Lei Zhou,Lin Fu,Na Lv,Jing Liu,Yan Li,Xiaosu Chen,Qingyu Xu,Guofeng Chen,Baoxu Pang,Lili Wang,Yonghui Li,Xiaodong Zhang,Li Yu 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-
The AML1-ETO fusion protein (A/E), which results from the t(8;21) translocation, is considered to be a leukemiainitiating event. Identifying the mechanisms underlying the oncogenic activity of A/E remains a major challenge. In this study, we identified a specific down-regulation of brain acid-soluble protein 1 (BASP1) in t(8;21) acute myeloid leukemia (AML). A/E recognized AML1-binding sites and recruited DNA methyltransferase 3a (DNMT3a) to the BASP1 promoter sequence, which triggered DNA methylation-mediated silencing of BASP1. Ectopic expression of BASP1 inhibited proliferation and the colony-forming ability of A/E-positive AML cell lines and led to apoptosis and cell cycle arrest. The DNMT inhibitor decitabine up-regulated the expression of BASP1 in A/E-positive AML cell lines. In conclusion, our data suggest that BASP1 silencing via promoter methylation may be involved in A/E-mediated leukemogenesis and that BASP1 targeting may be an actionable therapeutic strategy in t(8;21) AML.