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Xiao‑xia Ma,Yi‑ning Wang,Xiao‑an Cao,Xue‑rui Li,Yong‑sheng Liu,Jian‑hua Zhou,Xue‑peng Cai 한국유전학회 2018 Genes & Genomics Vol.40 No.9
The nucleocapsid (N) protein of peste des petits ruminants virus (PPRV) with a conserved amino acid usage pattern plays an important role in viral replication. The primary objective of this study was to estimate roles of synonymous codon usages of PPRV N gene and tRNA abundances of host in the formation of secondary structure of N protein. The potential effects of synonymous codon usages of N gene and tRNA abundances of host on shaping different folding units (α-helix, β-strand and the coil) in N protein were estimated, based on the information about the modeling secondary structure of PPRV N protein. The synonymous codon usage bias was found in different folding units in PPRV N protein. To better understand the role of translation speed caused by variant tRNA abundances in shaping the specific folding unit in N protein, we modeled the changing trends of tRNA abundance at the transition boundaries from one folding unit to another folding unit (β-strand → coil, coil → β-strand, α-helix → coil, coil → α-helix). The obvious fluctuations of tRNA abundance were identified at the two transition boundaries (β-strand → coil and coil → β-strand) in PPRV N protein. Our findings suggested that viral synonymous codon usage bias and cellular tRNA abundance variation might have potential effects on the formation of secondary structure of PPRV N protein.
Peng Cao,Lan-Ying Liu,Xue-Ting Cai,Xiao-Ning Wang,Jie-Ge Huo,Zhong-Ying Zhou 셀메드 세포교정의약학회 2012 셀메드 (CellMed) Vol.2 No.2
Fever in cancer patients is often due to the following causes: evil qi and toxity stagnancy, disorders of qi and blood, deficiencies of zang and fu organs, and the disorder of yin and yang. The treatments given to cancer patients with a fever are according to five: (a) Excessive inner heat and toxicants: remove heat and the toxicant, induce purgation. We use Cheng-Qi-Tang plus Qing-Wen-Bai-Du-Yin. (b) Tangle of damp and heat, and qi stagnancy: remove damp and heat, smooth the qi channel. We use Gan-Lu-Xiao-Du-Dan or San-Ren-Tang. (c) Obvious blood and heat stagnancy: remove heat and blood stasis. We use Xue-Fu-Zhu-Yu-Tang. (d) Deficiency of spleen qi, inner heat caused by a yin deficiency: nourish spleen qi and yin to remove the inner heat. We use Bu-Zhong-Yi-Qi-Tang or Xiao-Jian-Zhong-Tang. (e) Prominent yin deficiency and hectic fever: replenish yin and remove inner heat. We use Qing-Hao-Bie-Jia-Tang or Chai-Qian-Mei-Lian-San. The pathogenesis of fever in cancer patients is complicated. We can see both deficiency and excess in one differentiation. Therefore, we must make sure of it, then we can get the most effective treatment.
Interval-valued Analytic Network Process and its Application in Risk Assessment of Dynamic Alliance
Xiao-Guang Zhou,Yan-Hui Zhou,Xiao-Xiao Cui 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.9
Analytic Network Process (ANP) has been widely used in solving many complicated decision making problems. An approach to acquire the comprehensive weights of interval-valued Analytic Network Process (IV-ANP) is proposed. Firstly, the independent local interval-valued weights are obtained by solving the goal programming for interval-valued pairwise comparison matrices. Based on the interaction and feedback relationships among criteria and/or indices, an unweighted interval-valued supermatrix is formed. To avoid loss of information, an extreme value method is developed for acquiring the global weights of IV-ANP. Secondly, the alternatives are ranked on the basis of interval-valued preference order. Finally, with the interaction and feedback relationships between criteria and/or indices being considered, an index system for assessing the risk of dynamic alliance is presented. With the uncertain and inaccurate information during the evaluation process being considered, the proposed IV-ANP method is applied for risk assessment of dynamic alliance, and sensitivity analyses for some key risk factors are performed to show their impacts on the risk levels of alliance enterprises.
Couple-group L2-L∞ Consensus of Nonlinear Multi-agent Systems with Markovian Switching Topologies
Xiao Li,Cancan Zhou,Jianping Zhou,Zhen Wang,Jianwei Xia 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.3
The paper is devoted to the couple-group L2-L∞ consensus problem of nonlinear multi-agent systemsaffected by external disturbances. The interaction topologies among agents obey a continuous-time Markovianprocess with unknown transition probabilities. By a system transformation, the problem of couple-group L2-L∞ consensus is converted into a L2-L∞ control issue. Then, by Lyapunov stability theory and graph theory, sufficientconditions for the couple-group L2-L∞ consensus are obtained. The control gains can be acquired via the solutionsof a group of linear matrix inequalities. Moreover, the present method is extended to the multi-group L2-L∞consensus. Finally, an example is provided to illustrate the effectiveness of the results.
Xiao-Quan Xu,Sheng Liu,Qing-Quan Zu,Lin-Bo Zhao,Jin-Guo Xia,Chun-Gao Zhou,Wei-Zhong Zhou,Hai-Bin Shi 대한신경과학회 2013 Journal of Clinical Neurology Vol.9 No.2
Background and Purpose This study evaluated the clinical value of detachable-balloon embolization for traumatic carotid-cavernous fistula (TCCF), focusing on the frequency, risk factors, and retreatment of recurrence. Methods Fifty-eight patients with TCCF underwent transarterial detachable-balloon embolization between October 2004 and March 2011. The clinical follow-up was performed every 3months until up to 3 years postprocedure. Each patient was placed in either the recurrence group or the nonrecurrence group according to whether a recurrence developed after the first procedure. The relevant factors including gender, fistula location, interval between trauma and the interventional procedure, blood flow in the carotid-cavernous fistula, number of balloons, and whether the internal carotid artery (ICA) was sacrificed were evaluated. Results All 58 TCCFs were successfully treated with transarterial balloon embolization, including 7 patients with ICA sacrifice. Recurrent fistulas occurred in seven patients during the follow-up period. Univariate analysis indicated that the interval between trauma and the interventional procedure (p=0.006) might be the main factor related to the recurrence of TCCF. The second treatments involved ICA sacrifice in two patients, fistula embolization with balloons in four patients, and placement of a covered stent in one patient. Conclusions Detachable balloons can still serve as the first-line treatment for TCCFs and recurrent TCCFs despite having a nonnegligible recurrence rate. Shortening the interval between trauma and the interventional procedure may reduce the risk of recurrence.
Preparation of Homogeneous Microstructure Pure Lead Metaniobate by Two-Step Sintering
Xiao-gang Zhao,Peng Liu,Bo Chao,Su Juan Liu,Ming Pang,Xiao-Ming Chen,Jian-Ping Zhou 대한금속·재료학회 2014 ELECTRONIC MATERIALS LETTERS Vol.10 No.1
The purpose of the present work is to obtain the Lead metaniobate ceramics with the orthorhombic phase via a two-step sintering method. The samples were first sintered at 1320°C for 10 min, and then sintered separately at 1260°C, 1220°C, and 1180°C for 4 h. All the ceramics show orthorhombic phase and homogeneous microstructure. It was found that the abnormal grain growth was restrained obviously.
F-LBQA : Fair Load Balancing QOS Algorithm in Overlay Network
ZHOU Xiao-Yan,Zhao Kai 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.3
Due to the traditional overlay network QOS routing algorithm fails to consider the effects of the resource bottleneck on the routing selection, it results in the local congestion of the system. Therefore, this paper proposes a fair load-balancing QOS overlay routing F-LBQAR algorithm. The algorithm introduces the resource fairness index, sets up a new load-balancing utility function, and adopts the adaptive weighted method in the system’s load state to correct the weight restriction of QOS. The experimental results show that the algorithm in this paper can reduce the probability of network congestion caused by resources bottleneck and improve the QOS service success rate and the throughput of the system.
Triterpenoids and Sterones from the Stem Bark of Ailanthus altissima
Zhou, Xiao-Jiang,Xu, Min,Li, Xue-Song,Wang, Yue-Hu,Gao, Ye,Cai, Rui,Cheng, Yong-Xian Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.1
One new tirucallane-type triterpenoid, alianthusaltinin A (1), one new $C_{29}$ sterone, alianthaltone A (2), and 12 known compounds have been isolated from the stem bark of Ailanthus altissima. The structures of new compounds were identified by means of spectroscopic methods. Compound 3 was isolated from natural sources for the first time, and compounds 4, 5, and 9 were isolated from this plant for the first time.
Zhou, Xiao-Qing,Li, Ying,Sun, Yan-Bo,Zhang, Hong-Xing Korean Chemical Society 2011 대한화학회지 Vol.55 No.3
Quantum-chemistry study was explored to investigate the electronic structures, absorption and phosphorescence mechanism, as well as electroluminescence (EL) properties of three red-emitting Ir(III) complexes, $(fpmqx)_2Ir$(L) {fpmqx=2-(4-fluorophenyl)-3-methyl-quinoxaline; L=triazolylpyridine (trz) (1); L=picolinate (pic) (2) and L=acetylacetonate (acac) (3)}. The calculated results show that the HOMO distribution for 1 is mainly localized on trz moiety due to its stronger ${\pi}$-electron acceptor ability, and HOMO for 2 and 3 is the combination of Ir d- and phenyl ring ${\pi}$-orbital. The higher phosphorescence yields and differences among 1-3 are investigated in this paper. In addition, the reasons of higher EL efficiency of 2 than 1 and 3 have been rationalized. 3개의 적색 발광 Ir(III) 착물들인 $(fpmqx)_2Ir$(L) {fpmqx=2-(4-fluorophenyl)-3-methyl-quinoxaline; L=triazolylpyridine (trz) (1); L=picolinate (pic) (2) and L=acetylacetonate (acac) (3)}의 전자 구조, 흡수 및 인광 메커니즘, 전기 발광(EL) 특성을 양자화학적으로 연구하였다. 계산 결과에 따르면, 1의 HOMO는 강한 ${\eth}$-전자 받개 능력을 갖는 trz 부분에 편재되어 있으며, 2와 3의 HOMO는 Ir d-오비탈 과 페닐 고리 ${\pi}$-오비탈의 결합이라는 것을 나타내었다. 이 논문에서는 1-3사이의 인광 수득률과 차이에 대하여 연구하였으며, 1과 3보다 2의 EL 효율이 더 큰 이유를 합리적으로 설명하였다.