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      • 小说对话中的管领语

        吴卸耀 대구대학교 인문과학연구소 2008 人文科學硏究 Vol.32 No.-

        The position of controller in traditional Chinese novels only presented before the turn‐talking. But in modern novels controllers can be putted in the middle or behind of turn‐talkings. After studying, we found that, there are three elements that effect the position of controllers, the first is time principle, the second is the angle of narration, the third is the features of turn‐talkings. This studying is very important to understand novel’s narration.

      • 小说对话中的管领语

        吴卸耀 대구대학교 인문과학연구소(인문과학 예술문화연구소) 2008 人文科學硏究 Vol.32 No.-

        The position of controller in traditional Chinese novels only presented before the turn‐talking. But in modern novels controllers can be putted in the middle or behind of turn‐talkings. After studying, we found that, there are three elements that effect the position of controllers, the first is time principle, the second is the angle of narration, the third is the features of turn‐talkings. This studying is very important to understand novel’s narration.

      • KCI등재

        Preparation of Monascus-fermented ginkgo seeds: optimization of fermentation parameters and evaluation of bioactivity

        Wu Zhihao,Miao Wen,Yang Yuhan,Fan Gongjian,Wu Caie,Li Tingting,Xie Chunyan,Shen Dongbei 한국식품과학회 2022 Food Science and Biotechnology Vol.31 No.6

        In this study, a high monacolin K yield was achieved through solid-state fermentation of Ginkgo biloba seeds. Monascus purpureus suspension made from red yeast rice was used as spore inoculum. Fermentation conditions in solid-state fermentation were optimized using response surface methodology, and the optimal conditions for the maximum monacolin K yield (17.71 ± 1.57 mg/g) were 0.22% ammonium sulfate, 0.34% ammonium chloride, 0.05% magnesium sulfate, fermentation time of 12 days, inoculation volume of 11%, and temperature of 27 °C. The total phenolic content of Monascus-fermented ginkgo seeds attained 9.67 mg GAE/g, 4.88-fold higher than that of unfermented ginkgo seeds. The scavenging abilities of DPPH and ABTS free radicals increased to 9.79 mg TE/g and 13.92 mg TE/g, respectively. These findings highlight the importance of investigating the optimal fermentation conditions for maximum monacolin K yield and the utilization value of ginkgo seed as fermentation substrate for higher bioactivities.

      • Comprehensive Bioinformation Analysis of the MRNA Profile of Fascin Knockdown in Esophageal Squamous Cell Carcinoma

        Wu, Bing-Li,Luo, Lie-Wei,Li, Chun-Quan,Xie, Jian-Jun,Du, Ze-Peng,Wu, Jian-Yi,Zhang, Pi-Xian,Xu, Li-Yan,Li, En-Min Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

        Background: Fascin, an actin-bundling protein forming actin bundles including filopodia and stress fibers, is overexpressed in multiple human epithelial cancers including esophageal squamous cell carcinoma (ESCC). Previously we conducted a microarray experiment to analyze fascin knockdown by RNAi in ESCC. Method: In this study, the differentially expressed genes from mRNA expression profilomg of fascin knockdown were analyzed by multiple bioinformatics methods for a comprehensive understanding of the role of fascin. Results: Gene Ontology enrichment found terms associated with cytoskeleton organization, including cell adhesion, actin filament binding and actin cytoskeleton, which might be related to fascin function. Except GO categories, the differentially expressed genes were annotated by 45 functional categories from the Functional Annotation Chart of DAVID. Subpathway analysis showed thirty-nine pathways were disturbed by the differentially expressed genes, providing more detailed information than traditional pathway enrichment analysis. Two subpathways derivated from regulation of the actin cytoskeleton were shown. Promoter analysis results indicated distinguishing sequence patterns and transcription factors in response to the co-expression of downregulated or upregulated differentially expressed genes. MNB1A, c-ETS, GATA2 and Prrx2 potentially regulate the transcription of the downregulated gene set, while Arnt-Ahr, ZNF42, Ubx and TCF11-MafG might co-regulate the upregulated genes. Conclusions: This multiple bioinformatic analysis helps provide a comprehensive understanding of the roles of fascin after its knockdown in ESCC.

      • 小说对话中的管领语

        ??耀(WU XIE-YAO) 대구대학교 인문과학연구소 2008 人文科學硏究 Vol.32 No.-

        The position of controller in traditional Chinese novels only presented before the tum-talking. But in modem novels controllers can be putted in the middle or behind of turn-talkings. After studying, we found that, there are three elements that effect the position of controllers, the first is time principle, the second is the angle of narration, the third is the features of turn-talkings. This studying is very important to understand novel's narration.

      • KCI등재

        Decreased vitamin D-binding protein level portends poor outcome in acute-on-chronic liver failure caused by hepatitis B virus

        Daxian Wu,Qunfang Rao,Zhongyang Xie,Xiaoqing Zhu,Jian Wu,Hainv Gao,Jingyu Zhang,Zhouhua Hou,Xiaoyu Cheng,Zeyu Sun 대한간학회 2022 Clinical and Molecular Hepatology(대한간학회지) Vol.28 No.4

        Background/Aims: Acute-on-chronic liver failure (ACLF) is a catastrophic illness. Few studies investigated the prognostic value of vitamin D-binding protein (VDBP) for hepatitis B virus (HBV)-related ACLF (HBV-ACLF) resulted in conflicting results. Methods: Two prospective HBV-ACLF cohorts (n=287 and n=119) were enrolled to assess and validate the prognostic performance of VDBP. Results: VDBP levels in the non-survivors were significantly lower than in the survivors (P<0.001). Multivariate Cox regression demonstrated that VDBP was an independent prognostic factor for HBV-ACLF. The VDBP level at admission gradually decreased as the number of failed organs increased (P<0.001), and it was closely related to coagulation failure. The areas under the receiver operating characteristic curve (AUCs) of the Child-Pugh-VDBP and chronic liver failuresequential organ failure assessment (CLIF–SOFA)-VDBP scores were significantly higher than those of Child-Pugh (P<0.001) and CLIF-SOFA (P=0.0013). The AUCs of model for end-stage liver disease (MELD)-VDBP were significantly higher than those of MELD (P= 0.0384) only in the case of cirrhotic HBV-ACLF patients. Similar results were validated using an external multicenter HBV-ACLF cohort. By longitudinal observation, the VDBP levels gradually increased in survivors (P=0.026) and gradually decreased in non-survivors (P<0.001). Additionally, the VDBP levels were found to be significantly decreased in the deterioration group (P=0.012) and tended to be decreased in the fluctuation group (P=0.055). In contrast, they showed a significant increase in the improvement group (P=0.036). Conclusions: The VDBP was a promising prognostic biomarker for HBV-ACLF. Sequential measurement of circulating VDBP shows value for the monitoring of ACLF progression.

      • KCI등재

        중국 진·한(秦·漢) 시대의 전통 와당 문양을 활용된 심벌 디자인에 관한 연구 -베이징 지역의 공공시설에 중심으로-

        사무하 ( Xie Wu Xia ),박용진 ( Park Yong Jin ),김진성 ( Kim Jin Sung ) 한국기초조형학회 2017 기초조형학연구 Vol.18 No.4

        중국 고대 문화에는 전통 문양이 다양하게 형성 되어 있으며 이것이 중국 민족의 역사와 사회의 발전을 대표하는 상징일 뿐만 아니라 국가적 문화자산이며 세계적으로도 문화 예술적 가치가 있다. 중국 진·한(秦·漢) 시대의 통치자가 6개국을 통일한 후에 대규모 토목 공사를 통해 와당(기와)을 대량 사용하여 와당 문양의 형태 및 주제를 다양하게 발전시켰다. 와당문양은 장수와 부귀 등 여러 가지 의미를 상징하기 때문에 예로부터 사람들의 사랑을 많이 받아오고 있다. 관련된 선행연구를 살펴보면, 와당의 역사적 발전이나 건축 소재로 장식에 대한 연구를 많이 하였다. 그러나 그 시대의 문화 배경에서 와당문양은 독특한 예술 품격을 형성하여, 차별성을 보여주고 있기 때문에 현대의 디자인에 적용할 수 있는 요소가 많다. 그래서 문양의 풍부한 디자인 요소가 현대디자인 분야에 어떻게 적용하게 되는지 많은 연구가 필요하다. 본 연구는 중국 진·한(秦·漢) 시대의 전통 와당 문화 요소의 현대적 적용을 중심으로 베이징 지역에 있는 의료, 교육문화에 관한 공공시설 심벌디자인에 적용된 사례를 분석하였다. 이론적 고찰을 통해 와당 문양의 기원 및 발전을 파악하고 종류나 특징과 같은 표현 형식을 분석하였다. 와당 문양 및 공공시설 심벌디자인의 관계를 검토하고 와당문양이 공공시설 심벌디자인에 적용된 현황 분석을 통해 공공시설의 심벌디자인에 적용된 와당문양이 어떠한 특성을 가지는지에 대해서 연계하여 해석하고자 한다. 분석된 연구 결과를 토대로 와당 문양을 공공시설 심벌디자인에 적용하는 방법을 찾으려 하였으며, 현대 디자인에 전통 와당 문양을 잘 적용할 수 있는 디자인 가이드라인을 구축하는 것을 목적을 두고 연구하였다. In Chinese traditional culture, the traditional pattern, with full of variety and brilliance, represents not only Chinese nation`s long history as well as social development, but also a great treasure to global art and culture. Eaves tile began to be put into use widely, because the whole nation went in for large-scale construction after it was united as one in Qin and Han dynasties. Therefore, more and more decorative patterns and themes were created, when eaves tiles reached their greatest prosperity in that period. Different patterns corresponded to different wishes, such as longevity, wealth and safety. As a result, eaves tiles were popular among people in all ages. Most academic researches have focused on the history of tiles and their usage as building materials. However, influenced by the history and culture, eaves tile pattern in Qin and Han Dynasties has formed its unique artistic style which can be applied in the modern design. Therefore, the better application and combination of traditional art and modern culture is a valuable research worth studying. In order to study the method of applying eaves tile patterns to the modern design, this paper will analyze cases about the usage of tile patterns in public sings(logo) of medical and educational facilities in Beijing. Firstly, the origin , development, types and characteristics of eaves tiles will be studied according to theoretical research. Then, this paper will analyze the relationship between tile pattern and public facilities logo design. Through the analysis of the existing cases, the techniques and methods of using tile patterns in the design of public facilities can be concluded. Meanwhile, guidelines about how to apply eaves tile pattern could be better put forward in the future.

      • KCI등재

        Identification of Long Non-Coding RNAs and Their Target Genes from Mycelium and Primordium in Model Mushroom Schizophyllum commune

        Tuheng Wu,Jian Chen,Chunwei Jiao,Huiping Hu,Qingping Wu,Yizhen Xie 한국균학회 2022 Mycobiology Vol.50 No.5

        Schizophyllum commune has emerged as the most promising model mushroom to study developmental stages (mycelium, primordium), which are two primary processes of fruit body development. Long non-coding RNA (lncRNA) has been proved to participate in fruit development and sex differentiation in fungi. However, potential lncRNAs have not been identified in S. commune from mycelium to primordium developmental stages. In this study, lncRNA-seq was performed in S. commune and 61.56 Gb clean data were generated from mycelium and primordium developmental stages. Furthermore, 191 lncRNAs had been obtained and a total of 49 lncRNAs were classified as differently expressed lncRNAs. Additionally, 26 up-regulated differently expressed lncRNAs and 23 down-regulated between mycelium and primordia libraries were detected. Further, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that differentially expressed lncRNAs target genes from the MAPK pathway, phosphatidylinositol signal, ubiquitin-mediated proteolysis, autophagy, and cell cycle. This study provides a new resource for further research on the relationship between lncRNA and two developmental stages (mycelium, primordium) in S. commune.

      • SCIESCOPUSKCI등재
      • KCI등재

        SiC IGBT degradation mechanism investigation under HV‑H3TRB tests

        Ziming Wu,Zongbei Dai,Jian Zhou,Huafeng Dong,Wencan Wang,Feiwan Xie,Haoran Wang,Jiahui Yan,Xiyu Chen,Shaohua Yang,Fugen Wu 전력전자학회 2024 JOURNAL OF POWER ELECTRONICS Vol.24 No.2

        The high voltage-high humidity-high temperature reverse bias (HV-H3TRB) test was utilized to evaluate the reliability of silicon carbide insulated gate bipolar transistors (SiC IGBTs). Moisture invasion often induces termination/passivation and metal corrosion. Therefore, the HV-H3TRB test is generally used to assess termination / passivation robustness. However, under the HV-H3TRB test conditions, gate quality degradation may occur. In this study, the dominant degradation mechanism of SiC IGBTs was investigated. The changes of the most sensitive static characteristics (e.g., threshold voltage, breakdown voltage, and leakage current) were recorded. The threshold voltage decreased and leakage current increased substantially after > 1000 h of HV-H3TRB tests under 85 ℃/85% RH climate conditions. Capacitance-voltage (C-V) curve measurements indicated that the mobile ions at the SiC/SiO2 interface or in the gate oxide likely caused the threshold-voltage instability in the SiC IGBTs after the HV-H3TRB tests. This instability can be recovered by applying a negative gate bias. Subsequent failure analysis confirmed no corrosion of metals or termination/passivation in the device, which indicates the robustness of the passivation (consisting of phosphor-silicate glass and Si3N4). Therefore, the gate quality appears to be a significant reliability risk for SiC IGBTs under high humidity, high temperature, and high voltage conditions.

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