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Performance of water-jet pump under acceleration
Wu Xian-Fang,Li Ming-Hui,Liu Houlin,Tan Minggao,Lu You-Dong 대한조선학회 2021 International Journal of Naval Architecture and Oc Vol.13 No.1
The instantaneous acceleration affects the performance of the water-jet pump obviously. Here, based on the user-defined function, the method to simulate the inner flow in water-jet pumps under acceleration conditions was established. The effects of two different acceleration modes (linear acceleration and exponential acceleration) and three kinds of different acceleration time (0.5s, 1s and 2s) on the performance of the water-jet pump were analyzed. The results show that the thrust and the pressure pulsation under exponential acceleration are lower than that under linear acceleration at the same time; the vapor volume fraction in the impeller under linear acceleration is 27.3% higher than that under exponential acceleration. As the acceleration time increases, the thrust gradually increases and the pressure pulsation amplitude at the impeller inlet and outlet gradually decreases, while the law of pressure pulsation is the opposite at the diffuser outlet. The main frequency of pressure pulsation at the impeller outlet is different under different acceleration time. The research results can provide some reference for the optimal design of water-jet pumps.
Modeling and Simulation of the Magnetic Method for High Voltage Direct Current Inspection Robot
Xian-jin Xu,Cheng-hui Liu,Yu Yan,Hao-da Chen,Lei Fang,Yun-long Wang,Long-hui Wu 한국자기학회 2018 Journal of Magnetics Vol.23 No.3
In order to solve the slipping problem of a two-arm-wheel combined inspection robot, a maglev system based on the magnetic field of a high voltage direct current (HVDC) is proposed. The magnetic system comprises of two parts: a magnetic levitation system and a magnetic drive system. The levitation component overcomes the gravity of the robot by the Ampere force generated by current-carrying coils in the magnetic field of HVDC. The drive component utilizes the Ampere force generated by current-carrying coils in the magnetic field of HVDC as the driving force. Simulation results of the model are compared with the calculated values. The results show that the magnetic levitation method and the magnetic drive method are theoretically feasible, and the model is accurate and effective, which is of great practical significance to the physical realization of the inspection robot.
Sequence Analysis of Mitochondrial Genome of Toxascaris leonina from a South China Tiger
Kangxin Li,Fang Yang,A. Y. Abdullahi,Meiran Song,Xianli Shi,Minwei Wang,Yeqi Fu,Weida Pan,Fang Shan,Wu Chen,Guoqing Li 대한기생충학열대의학회 2016 The Korean Journal of Parasitology Vol.54 No.6
Toxascaris leonina is a common parasitic nematode of wild mammals and has significant impacts on the protection of rare wild animals. To analyze population genetic characteristics of T. leonina from South China tiger, its mitochondrial (mt) genome was sequenced. Its complete circular mt genome was 14,277 bp in length, including 12 protein-coding genes, 22 tRNA genes, 2 rRNA genes, and 2 non-coding regions. The nucleotide composition was biased toward A and T. The most common start codon and stop codon were TTG and TAG, and 4 genes ended with an incomplete stop codon. There were 13 intergenic regions ranging 1 to 10 bp in size. Phylogenetically, T. leonina from a South China tiger was close to canine T. leonina. This study reports for the first time a complete mt genome sequence of T. leonina from the South China tiger, and provides a scientific basis for studying the genetic diversity of nematodes between different hosts.
Multi-size Numerical Simulation of Bubbles on Gas-liquid Two-Phase Flow in a Centrifugal Pump
Tan Minggao,Tong Qin,Wu Xian-Fang,Shao Chen,Ma Haochen 한국유체기계학회 2023 International journal of fluid machinery and syste Vol.16 No.4
In order to further understand the distribution and motion of gas phase in the gas-liquid two-phase flow inside a centrifugal pump, the numerical simulation on gas-liquid two-phase flow in the centrifugal pump was carried out and the CFD method was verified by experiment test. The MUSIG model was used as the multiphase flow model, coupled with the Prince-Blanch model and the Luo-Svendson model to describe the bubble breaking and coalescence process. The influence of inlet gas volume fraction and liquid flow rate on the gas-liquid two-phase flow inside centrifugal pump was investigated. The results show that the proportion of large bubbles in impeller is higher than that in volute. Large bubbles are mainly at the suction chamber inlet and impeller inlet, and small bubbles are mainly at the impeller outlet and volute outlet. From suction chamber, impeller to the volute, the average diameter of bubbles decreases in turn. With the increase of inlet gas volume fraction, the proportion of small bubbles in the pump decreases. Also, the flow pattern inside the pump gradually changes from bubble flow to gas pocket flow and the average diameter of bubbles in each flow passage component increases. With the increase of liquid flow rate, the proportion of small bubbles in the pump increases. Meanwhile, the flow pattern gradually changes from gas pocket flow to bubble flow and the average diameter of bubbles in each flow passage component decreases.
Xie, Cong-Ying,Jin, Xian-Ce,Deng, Xia,Xue, Sheng-Liu,Jing, Zhao,Su, Hua-Fang,Wu, Shi-Xiu Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12
Objectives: To evaluate the feasibility and efficacy of simultaneous accelerated radiation therapy (SMART) and concurrent weekly paclitaxel in the treatment of locally advanced nasopharyngeal carcinoma. Methods: Forty-one patients with pathologically confirmed nasopharyngeal carcinoma were treated by SMART with concurrent weekly paclitaxel. Daily fraction doses of 2.5 Gy and 2.0 Gy were prescribed to the gross tumor volume (GTV) and clinical target volume (CTV) to a total dose of 70 Gy and 56 Gy, respectively. Paclitaxel of $45mg/m^2$ was administered concurrently with radiation therapy every week. Adjuvant chemotherapy was given four weeks after the completion of the radiotherapy (RT) if the tumor demonstrated only a partial response (PR). Results: All patients completed the radiotherapy (RT) course. Adjuvant chemotherapy was administered to 12 patients due to PR. The CR (complete remission) rate was 82.9% three months after RT. Thirty-nine (95.1%) patients completed the concurrent weekly chemotherapy with paclitaxel, and two patients skipped their sixth course. Seven patients had a 15% dosage reduction at the fifth and sixth course due to grade 3 mucositis. The median follow-up was 30 (range, 14-42) months. The three-year overall survival (OS), metastases-free survival (MFS), and local control rates were 77.0%, 64.4%, and 97.6%, respectively. No correlation between survival rate and T or N stage was observed. Grade 3 acute mucositis and xerostomia were present in 17.1% and 7.1%, respectively. Conclusion: SMART with concurrent weekly paclitaxel is a potentially effective and toxicity tolerable approach in the treatment of locally advanced NPC.
Flavones from the Bark of Lindera caudata and Their Anti-Tobacco Mosaic Virus Activity
Yu-Chun Yang,Ying Qin,Xian-Xue Wu,Cong-Fang Xia,Yan-Lin Meng,Bin Zhou,Yan-Qing Ye,Xue-Mei Gao,Yin-Ke Li,Qiu-Fen Hu 대한화학회 2015 Bulletin of the Korean Chemical Society Vol.36 No.4
Two new flavones, 5-hydroxy-8-hydroxymethyl-7,4′-dimethoxy-flavone (1) and 6-hydroxy-8-hydroxymethyl-7,4′-dimethoxy-flavone (2), together with six known flavones (3–8), were isolated from the bark of Lindera caudata. The structures of 1–8 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1–8 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that Compounds 1 and 2 showed high anti-TMV activity with inhibition rates of 31.2 and 28.8%, respectively. These values are close to those of positive control.
Wang, Chang-Dong,Yuan, Cheng-Fu,Bu, You-Quan,Wu, Xiang-Mei,Wan, Jin-Yuan,Zhang, Li,Hu, Ning,Liu, Xian-Jun,Zu, Yong,Liu, Ge-Li,Song, Fang-Zhou Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2
Fangchinoline (Fan) inhibits cell proliferation and induces apoptosis in several cancer cell lines. The effects of Fan on cell growth and proliferation in breast cancer cells remain to be elucidated. Here, we show that Fan inhibited cell proliferation in the MDA-MB-231 breast cancer cell line through suppression of the AKT/Gsk-3beta/cyclin D1 signaling pathway. Furthermore, Fan induced apoptosis by increasing the expression of Bax (relative to Bcl-2), active caspase 3 and cytochrome-c. Fan significantly inhibited cell proliferation of MDA-MB-231 cells in a concentration and time dependent manner as determined by MTT assay. Flow cytometry analysis demonstrated that Fan treatment of MDA-MB-231 cells resulted in cell cycle arrest at the G1 phase, which correlated with apparent downregulation of both mRNA and protein levels of both PCNA and cyclin D1. Further analysis demonstrated that Fan decreased the phosphorylation of AKT and GSK-3beta. In addition, Fan up-regulated active caspase3, cytochrome-c protein levels and the ratio of Bax/Bcl-2, accompanied by apoptosis. Taken together, these results suggest that Fan is a potential natural product for the treatment of breast cancer.
Zhang Qing,He Yi-Jing,Zhu Yu-Hang,Dai Min-Chen,Pan Man-Man,Wu Jia-Qi,Zhang Xian,Gu Ying-Er,Wang Fang-Fang,Xu Xiang-Rong,Qu Fan 한국한의학연구원 2020 Integrative Medicine Research Vol.9 No.3
Background: During the COVID-19 epidemic period, Traditional Chinese Medicine (TCM) course for international students of Medical Bachelor, Bachelor of Surgery (MBBS) program in Zhejiang University has shifted from traditional classroom to online environment. This study aimed to investigate MBBS international students’ perception on online TCM course, and to assess the online learning efficacy. Methods: A total of 84 MBBS international students attending course of “Basic Traditional Chinese Medicine” during 2020 academic years at Zhejiang University were enrolled in this study. A quantitative questionnaire was respectively completed before and after the TCM course using a pretest–post-test design. By means of two online learning platforms, Learning in ZJU and DingTalk, TCM course was broadcast in both live and archived format to students. Results: A total of 48 participants completed both baseline and follow-up questionnaires. The majority of participants preferred face-to-face classroom learning (26, 54.17% of total) when compared with online learning. Students felt that the course had brought in much benefits (mean 3.88, SD 0.87), and they were satisfied with the course content (mean 3.83, SD 0.95). Students’ TCM related knowledge and their behaviors of discussion and consulting were significantly improved by online TCM course (all P < 0.001). Students’ awareness of the necessity of TCM education and their feeling of difficulty in learning TCM were significantly strengthened (P = 0.042, 0.025, respectively). Conclusion: Online learning is a good alternative for TCM course of MBBS international students when classroom learning is suspended, whereas it cannot replace the need for onsite and face-to-face learning.