폴리메틸비닐케톤 및 메틸비닐케톤을 포함하는 공중합체들의 합성과 물성에 관한 연구

김영민,오상훈,조원제 부산대학교 공과대학 1987 硏究報告 Vol.34 No.-

The homopolymerization of methyl vinyl ketone was carried out with AIBN as an intiator in benzene under various conditions. From the result of kinetic investigation of methyl vinyl ketone, a rate equation was obtained. d[M] -------- = k_(p)[M][I]½ dt The overall activation energy for the polymerization was found to be 7Kcal/mole. Molecular weights of poly (methyl vinyl ketone) were measured by the Cannon-Fenske viscometer and GPC. Plot of intrinsic viscosity [η] versus Mw on a double logarithmic graph indicated the following equation [η]=77×10^(-5)Mw^(0.72) Poly (acetyl acetylene) was obtained by the reaction of poly (methyl vinyl ketone) with phosphorus oxychloride in chloroform at 0℃ under various reaction time. The radical copolymerizations of methyl vinyl ketone(MVK) with methyl methacrylate(MMA) and methyl acrylate (MA) were carried out with AIBN as an initiator at 50℃ in bulk. The specific extinction coefficients on poly(MVK-co-MMA) and poly (MVK-co-MA) were measured by means of UV spectrophotometer at 288nm in THF. From the calibration curves obtained by the different concentration ratios of each homopolymers, the following equations were derived. ε=0.0153+5.99×10^(-3)χ for poly (MVK-co-MMA) ε=0.112+1.102 χ for poly (MVK-co-MA) where ε is the specific extinction coefficient of the copolymer and χ is the weight fraction of MVK unit in the copolymer. The following monomer reactivity ratios were determined. r₁(MVK)=0.5 and r_(2)(MMA)=0.95 for poly (MVK-co-MMA) r₁(MVK)=1.85 and r_(2)(MA)=0.99 for poly (MVK-co-MA) From DSC thermal analysis, glass transition temperature (T_(g)) of PMVK and PMMA are 307˚K and 386˚K, respectively. The glass transition temperatures of copolymers were increased with increasing MMA component in copolymer. The conductivity of poly (acetyl acetylene) increased from 10^(-6) Ω^(-1) cm^(-1) to 10^(-4) Ω^(-1) cm^(-1) with increasing the reaction time of poly (methyl vinyl ketone) and phosphorus oxychloride. In the reaction of poly (MVK-co-MA) with phosphorus oxychloride in chloroform at 0℃, the conductivity of the obtained copolymer was 10^(-6) Ω^(-1) cm^(-1).

국산 및 수입 Luncheon Meat의 품질비교에 관한 연구

김천제,최수일,한의수,이효진,고원식 건국대학교 동물자원연구센터 1991 動物資源硏究誌 Vol.16 No.-

본 연구는 국내에서 생산되고 있는 돈육 luncheon meat과 수입 luncheon meat의 성분조성 및 품질을 비교 평가하기 위하여 실시하였다. 그 결과를 요약하면 다음과 같다. 1) 국산돈육 luncheon meat의 수분함량은 57.2%로 수입품(53.1%)보다 높았으며 조지방 함량은 수입품(53.1%)보다 높았으며 조지방 함량은 수입품이 26.6%로 국산품(20.6%)보다 높았다. 그러나 조단백질 함량은 거의 같았다. 2) 국산돈육 luncheon meat와 수입품 모두 대장균이 검출되지 않으며, 타르색소(tar colors)도 사용하지 않은 것으로 나타났다. 3) 국산돈육 luncheon meat의 NO₂의 함량은 4 ∼ 35ppm으로 돈육수입 luncheon meat(1.7∼6ppm)보다 높았다. 4) 국산돈육 luncheon meat의 TBA가는 0.09∼0.13로 비교적 낮았으나, 유통기간이 긴 수입돈육 luncheon meat는 0.09∼0.39로 국내제품에 비하여 상대적으로 높은 값을 나타내었다. 5) 국산돈육 luncheon meat의 VBN(12.3∼18.4mg%)은 수입품(15.7∼18.2mg%)보다 낮았다. 6) 수입 luncheon meat는 국산 luncheon meat보다 jelly loss가 약2배 높았다. 7) 경도는 국산돈육 luncheon meat통조림이 수입품보다 높은 것으로 나타났으나, 탄력성과 응집성은 큰 차이가 나지 않았다. The aim of this study was to assay and compare the ingredient or composition and quality of imported pork luncheon meat with those of domestic's. The results obtained were as follows. 1. The amount of water in domestic pork luncheon meat products(57.2%0 was higher than that of imported products(52.2%0, and the content of crude fat in imported products(26.6%) was higher than that of domestic products(20.6%). The amount of crude protein, however, both domestic and imported products was approximately the same. 2. E.coli was not found in both domestic and imported products. No tar-colors were detected in both samples. 3. The amount of NO₂in domestic pork luncheon meat products(4 to 35ppm) was higher than that of imported products(1.7 to 6ppm). 4. The TBA-value of domestic pork luncheon meat products(0.09 to 0.13) was relatively low, whereas the value of imported products was higher than that of domestic products(0.09 to 0.39). 5. The VBN-value of domestic luncheon meat products(12.3∼18.4mg%) was lower than that of imported products(15.7∼18.2mg%). 6. The jelly loss of imported pork luncheon meat products was approximately 2 times higher than that domestic's . 7. The hardness of imported pork luncheon meat products was lower than that of domestic products. Elasticity and coheshiveness in both products were not significantly different.

Poly (1-(2-Carbomethoxyacryloyl)-5-Fluorouracil)의 Drosophila 대사과정에 미치는 생리유전학적 영향에 관한 연구

李元鎬,金益成,趙元濟 부산대학교 환경문제 연구소 1985 環境硏究報 Vol.3 No.-

Genetic study on 5-fluorouracil(5-FU), 1-(2-carbomethoxyacryloyl)-5-fluorouracil(CMA-FU) and poly(CMAFU) treated in Drosophila melanogaster was undertaken by the adult feeding method of Lewis and Bacher. Toxic capacity, sex ratio, egg to adult viability, required developmental period, fecundity, and productivity induced by 5-FU, CMAFU, and poly(CMAU) had been analyzed. The results obtained were as follows: 1) The order of toxicity was decreased by 5-FU, CMAU, poly(CMAU) and control group. But there was no change by varying concentration. 2) The effects on the sex-chromosome were regarded by the sex ratio:In the control, sex ratio was 0.5349, in experimental groupⅠ treated with 5-FU 0.5862, in the groupⅡtreated with CMAFU 0.5747, and in the groupⅢ treated with poly (CMAFU) 0.5758, respectively. The differences between control and experimental groups were not significant. 3) The egg to adult viability of OR females was 86 percent in the control group, 0 in the experimental groupⅠ, 60 percent in the experimental groupⅡ, and 65 percent in the experimental groupⅢ. 4) The reguired developmental periods were calculated to be 9.43 days in the control group, 0 in the experimental groupⅠ,13.29 days in the group Ⅱ, and 13.23 days in the group Ⅲ. 5) The fecundities appeared from the first to the fifth culture were 16 eggs in the control group,12 in the experimental group Ⅰ,Ⅱ, and 13 in the groupⅢ, respecively. 6) The productivities were calculated to be 178 in the control, 0 in the experimental groupⅠ, 152 in the groupⅡ, and 186 in the groupⅢ. 7) It is found that a physiological genetic effect on the Drosophila melanogaster is much weaker for CMAFU and poly (CMAFU) than for 5 FU.

합성펩타이드를 이용한 영양배엽세포-특이 가토 다클론 항혈청의 제작

이희섭,오재민,김정중,문형배,김원신,이황희 원광대학교 생명공학연구소 1995 생명공학연구소보 Vol.3 No.1

Within the last few years, a different approach to generating protein-reactive antibodies has been developed that has several advantages over conventional immunization. This involves synthesizing short peptide sequences, coupling them to immunogenic carrier molecules, and immunizing animals with the conjugates. 3βHSD(3β-hydroxy-5-ene steroid dehydrogenase; EC 1.1.1.145) is the enzyme of the plasma membrane of human trophoblast and it's cDNA sequence was identified by Nickon et al(Molecular cloning and expression of human trophoblast antigen FDO161G and its identification as 3β-hydroxy-5-ene steroid dehydrogenase. J Reprod Fert 1991;149;156). For the production of trophoblast-specific antibody, we synthesized three oligopeptides that are epitope sites chosen from cDNA sequence of 3βHSD. Oligopetides were coupled with KLH(keyhole limpet hemocyanin) under 25% glutaraldehyde. The trophoblast-specific rabbit polyclonal antisera was produced by conventional methods. This antisera reacts with a 43kDa protein in human placental lysate by Western blotting analysis and The syncytiotrophoblasts and cytotrophoblasts from villi are stained positively with this antisera by immunohistochemistry. Villous trophoblasts were cultured in methionine-free media for 1 hour and [^(35)S]-Methionine for 24 hours. Media and cell lysate were immunoprecipitated with this antisera and 12% SDS-PAGE was performed. In fluorography, bend was not noted in media and 43kDa band was noted in medis and 43kDa band was noted in lysate. It was concluded that anti-3βHSD antibody produced by synthetic peptide was specific to trophoblasts and 3βHSD was membrane-bound protein of trophoblasts.

Treatment Technology for Contaminated Water Containing Iodine

Jei-Won Yeon,TaeJun Kim,Minsik Kim 한국방사성폐기물학회 2019 한국방사성폐기물학회 학술논문요약집 Vol.2019 No.10

Random Block-Based Video Watermarking of H.264/SVC

Won Jei Kim,Kwang-Seok Moon,MD Abul Bashar,Young-Ho Ahn,Suk-Hwan Lee,Yong-Su Seo,Ki-Ryong Kwon 한국멀티미디어학회 2008 한국멀티미디어학회 국제학술대회 Vol.2008 No.-

In this paper, we proposed random block-based video watermarking of H.264/SVC(scalable video coding). In proposed scheme, the embedding of watermark is performed in H.264/SVC encoder. Our scheme use the block that is decided by length of the watermark and size of the video frame. And then the block randomly selected by random position key. With the proposed method, the video watermarking scheme can achieve high robustness and good visual quality without increasing the overall bit-rate. Experimental results show that our scheme can robustly survive encoding, common signal processing and geometrical processing.

Ovarian Features after 2 Weeks, 3 Weeks and 4 Weeks Transdermal Testosterone Gel Treatment and Their Associated Effect on IVF Outcomes in Poor Responders

Kim, Chung-Hoon,Ahn, Jun-Woo,Moon, Jei-Won,Kim, Sung-Hoon,Chae, Hee-Dong,Kang, Byung-Moon 한국발생생물학회 2014 발생과 생식 Vol.18 No.3

This study was performed to investigate the effect of of transdermal testosterone gel (TTG) on controlled ovarian stimulation (COS) and IVF outcomes and ovarian morphology according to pretreatment duration in poor responders. A total of 120 women were recruited for this pilot study. They were randomized into control, 2 weeks, 3 weeks or 4 weeks TTG treatment groups. For three TTG treatment groups, 12.5 mg TTG was applied daily for 2 weeks, 3 weeks or 4 weeks in preceding period of study stimulation cycle. After 3 weeks of TTG pretreatment, significant increase of antral follicle count (AFC) and significant decreases of mean follicular diameter (MFD) and resistance index (RI) value of ovarian stromal artery were observed (p=0.026, p<0.001, p<0.01, respectively). The total dose of rhFSH administered for COS significantly decreased after 3 and 4 weeks TTG treatment both compared with control group (p<0.001, p<0.001). The numbers of oocytes retrieved and mature oocytes were significanty higher in 3 and 4 weeks TTG treatment groups than control group (p<0.001, p<0.001 in the number of oocytes retrieved; p<0.001, p<0.001 in the number of mature oocytes). The clinical pregnancy rate and live birth rate were increased only in 4 weeks TTG treatment group compared with control group (p=0.030 and p=0.042, respectively). These data demonstrated that TTG pretreatment for 3 to 4 weeks increases AFC and ovarian stromal blood flow, thereby potentially improving the ovarian response to COS and IVF outcome in poor responders undergoing IVF/ICSI.

Remediation of soil/concrete contaminated with uranium and radium by biological method

Kim, Gye-Nam,Kim, Seung-Su,Park, Hye-Min,Kim, Won-Suk,Park, Uk-Ryang,Moon, Jei-Kwon Springer-Verlag 2013 Journal of radioanalytical and nuclear chemistry Vol.297 No.1

Plasma MicroRNA-21, 26a, and 29a-3p as Predictive Markers for Treatment Response Following Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma

Kim, Soon Sun,Cho, Hyo Jung,Nam, Ji Sun,Kim, Hyun Ji,Kang, Dae Ryong,Won, Je Hwan,Kim, Jinoo,Kim, Jai Keun,Lee, Jei Hee,Kim, Bo Hyun,Lee, Mi Young,Cho, Sung Won,Cheong, Jae Youn KOREAN ACADEMY OF MEDICAL SCIENCE 2018 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.33 No.1

<P><B>Background</B></P><P>We investigated an association between the levels of plasma microRNA (miRNA)-21, -26a, and -29a-3p and treatment outcomes following transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC).</P><P><B>Methods</B></P><P>A total of 198 patients with TACE-treated HCC were followed up for TACE refractoriness and liver transplantation (LT)-free survival. Pretreatment plasma miRNA-21, -26a, and -29a-3p levels were measured using quantitative real-time polymerase chain reaction.</P><P><B>Results</B></P><P>During the mean follow-up of 22.3 (range, 0.7–79) months, 118 (59.6%) patients exhibited TACE refractoriness. Multivariate analyses showed that expression of a specific combination of miRNAs (miRNA-21 ≥ 2.5, miRNA-26a ≥ 1.5, and miRNA-29a-3p < 0.4) was associated with early TACE refractoriness (within 1 year; hazard ratio [HR], 2.32; 95% confidence interval [CI], 1.08–4.99; <I>P</I> = 0.031) together with tumor size (HR, 4.62; 95% CI, 1.50–14.21; <I>P</I> = 0.008), and macrovascular invasion (HR, 3.80; 95% CI, 1.19–12.20; <I>P</I> = 0.025). However, miRNA-21, -26a, and -29a-3p levels were not significantly associated with overall TACE refractoriness or LT-free survival. Additionally, large tumor size and macrovascular invasion were common predictive factor of overall TACE refractoriness and survival.</P><P><B>Conclusion</B></P><P>Combination of plasma miRNA-21, -26a, and -29a-3p expression could predict early TACE refractoriness in patients with TACE-treated HCC.</P>

H.264 Scalable Extension을 위한 비디오 워터마킹 및 암호화 기반의 정보보호 기법

김원제(Won-Jei Kim),성택영(Teak-Young Seung),이석환(Suk-Hwan Lee),권기룡(Ki-Ryong Kwon) 한국멀티미디어학회 2012 멀티미디어학회논문지 Vol.15 No.3