A Study on the Cooperation Potential and Influencing Factors of Korea-China Digital Trade

Wang Xin-yue 한국무역학회 2023 한국무역학회 학술대회 Vol.2023 No.4

Taxol Produced from Endophytic Fungi Induces Apoptosis in Human Breast, Cervical and Ovarian Cancer Cells

Wang, Xin,Wang, Chao,Sun, Yu-Ting,Sun, Chuan-Zhen,Zhang, Yue,Wang, Xiao-Hua,Zhao, Kai Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1

Currently, taxol is mainly extracted from the bark of yews; however, this method can not meet its increasing demand on the market because yews grow very slowly and are a rare and endangered species belonging to first-level conservation plants. Recently, increasing efforts have been made to develop alternative means of taxol production; microbe fermentation would be a very promising method to increase the production scale of taxol. To determine the activities of the taxol extracted from endophytic fungus N. sylviforme HDFS4-26 in inhibiting the growth and causing the apoptosis of cancer cells, on comparison with the taxol extracted from the bark of yew, we used cellular morphology, cell counting kit (CCK-8) assay, staining (HO33258/PI and Giemsa), DNA agarose gel electrophoresis and flow cytometry (FCM) analyses to determine the apoptosis status of breast cancer MCF-7 cells, cervical cancer HeLa cells and ovarian cancer HO8910 cells. Our results showed that the fungal taxol inhibited the growth of MCF-7, HeLa and HO8910 cells in a dose-and time-dependent manner. IC50 values of fungal taxol for HeLa, MCF-7 and HO8910 cells were $0.1-1.0{\mu}g/ml$, $0.001-0.01{\mu}g/ml$ and $0.01-0.1{\mu}g/ml$, respectively. The fungal taxol induced these tumor cells to undergo apoptosis with typical apoptotic characteristics, including morphological changes for chromatin condensation, chromatin crescent formation, nucleus fragmentation, apoptotic body formation and G2/M cell cycle arrest. The fungal taxol at the $0.01-1.0{\mu}g/ml$ had significant effects of inducing apoptosis between 24-48 h, which was the same as that of taxol extracted from yews. This study offers important information and a new resource for the production of an important anticancer drug by endofungus fermentation.

Research on the Efficiency and Influencing Factors of Korea's Foreign Direct Investment in RCEP Partners

Wang Xin-Yue,Xi Chen,Li Chen,Qing Wang 한국무역학회 2022 Journal of Korea trade Vol.26 No.4

Purpose – In this paper, we, taking South Korea's foreign direct investment in RCEP partners as an example, will examine its investment efficiency in these countries and analyze the main influencing factors, making suggestions for further liberalizing and facilitating its investment in and even for promoting its trade and economic cooperation with them. Design/methodology – In this study, we look at the panel data of South Korea and the other 13 RCEP countries (Brunei excluded) from 2000 to 2019 and apply the stochastic frontier analysis to measure its foreign direct investment efficiency and explore the influencing factors in RCEP countries. We examine the investment potential of South Korea in these places. Findings – We find that South Korea's average investment efficiency in RCEP countries reached 0.62, indicating large investment potential. We also find that its investment efficiency in RCEP partners was heterogeneous. Our study reveals that South Korea’s foreign direct investment is significantly positively correlated with the market size and population of the two countries, as well as with whether the host country has a coastline and rich natural resources, while negatively with geographic distance. It shows that free trade agreements, economic freedom, and regulatory quality play significant roles in improving investment efficiency. Originality/value – Through theoretical and empirical analysis, we deal with the efficiency and influencing factors of South Korea's direct investment in RCEP partners, proposing new drivers for facilitating its trade and investment in these countries and comprehensively evaluating the efficiency and revealing the trend of its FDI in these countries. In this paper, we put forward a solid theoretical basis for empirical analysis of the future economic and trade development between South Korea and its RCEP partners and give objective insights for further improving its foreign direct investment efficiency and tapping its investment potential.

ELECTROCHEMICAL Co 3 O 4 NANOPOROUS THIN FILMS SENSOR FOR HYDROGEN PEROXIDE DETECTION

GUANG SHENG CAO,RUILIN WANG,PEILONG WANG,XIN LI,YUE WANG,JUNPING LI,GUILONG WANG 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.4

The nanoporous Co 3 O 4 thin ¯lms were prepared on indium tin oxide (ITO) glasses by anelectrodeposition method. The surface morphology and composition of the nanoporous Co 3 O 4¯lms were characterized by scanning electron microscopy (SEM), energy-dispersive X-rayanalysis (EDS) and X-ray photoelectron spectroscopy (XPS). The results show that the as-deposited nanoporous Co 3 O 4 ¯lm is constructed by many interconnected nano°akes withthickness of about 40 nm. The cyclic voltammetry (CV) measurement indicates that thenanoporous Co 3 O 4 ¯lms exhibit remarkable electrocatalytic activities for the hydrogen peroxide(H 2 O 2 ) reduction which shows that it is a good candidate to be employed as electrode materialsfor electrochemical sensing of H 2 O 2 . Further analysis indicated that the detection sensitivityof the sensor was 1.357 mA mM? 1 cm? 2 and the detection limit was estimated to be about0.2 mM.

Influence of oxygen equivalent on molten salt oxidation efficiency of mixed resin in Li2CO3-Na2CO3-K2CO3 melt

Xin Liu,Zi-Yu Liu,Yang-Hai Zheng,Yong-De Yan,Wen-Da Xu,Yun Xue,Yue-Lin Wang,Fu-Qiu Ma,Kai Zhu,Yu-Sheng Yang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.120 No.-

The disposal of spent radioactive ion exchange resin generated during the operation of nuclear facilitieshas always been a conundrum. The molten salt oxidation (MSO) for the treatment of mixed resin (MR)shows obvious superiority. In this work, ternary carbonate (Li2CO3-Na2CO3-K2CO3) and MR was usedas the molten salt system and the oxidation target, respectively. The oxidation behavior of MR was analyzedby varying the temperature and oxygen equivalent during the MSO process. By studying the effectof different oxygen equivalents on the oxidation efficiency, the oxygen equivalent of 125% could make theoxidation efficiency of MR reach 99.99% at 800 C. The composition of C, N and S containing exhaust gasproduced through MSO process of MR with temperature were almost consistent with the simulationresults. The exhaust gas was successfully adsorbed by molten carbonate to produce nitrate and sulfurcompounds. The carbonate has good absorption to harmful gases such as SO2, CO, NO, etc. The contentof SO2 from the highest 0.32% to 0, and 71.23% of sulfur in MR was trapped by molten carbonate asthe form of sulfate. This work has important implications for reducing the potential harm of radioactivewaste resin to the environment.

DC‑side admittance model of converters with constant power control considering DC‑side voltage fluctuation

Xin Tang,Zhen Li,Yang He,Liyang Wang,Yufei Yue,Wen Wang 전력전자학회 2023 JOURNAL OF POWER ELECTRONICS Vol.23 No.2

In the stability analysis of DC (direct-current) power grids, AC (alternating current)/DC converters are usually treated as linear proportional amplifiers or inertial links. However, this approximation will have a considerable effect on the DC-side impedance model of a constant active power control converter and then affect the accuracy of the stability analysis of DC grids. In this paper, in view of the DC-side of the voltage fluctuations, the DC-side admittance model is established after the nonlinear relationship between the port voltage and the modulation signal function is determined. A comparison is made between the traditional modeling method and the proposed modeling method in the analysis of the phase–frequency characteristics and amplitude–frequency characteristics of the admittance. Results show that the proposed small-signal model can better fit the measured admittance in the low-frequency bands. The proposed admittance model in this paper is further applied to assess the small-signal stability of a DC grid. Finally, PSCAD/EMTDC simulation and lab-scaled prototype experiment are used to verify the correctness and effectiveness of the established admittance model. Results show that the small-signal model deduced in this paper can better fit and measure the admittance in the low-frequency band, and can more accurately judge the stability of the DC system.

Peptidoglycans Promotes Human Leukemic THP-1 Cell Apoptosis and Differentiation

Wang, Di,Xiao, Pei-Ling,Duan, Hua-Xin,Zhou, Ming,Liu, Jin,Li, Wei,Luo, Ke-Lin,Chen, Jian-Jun,Hu, Jin-Yue Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

The innate immune system coordinates the inflammatory response to pathogens. To do so, its cells must discriminate self from non-self utilizing receptors that identify molecules synthesized exclusively by microbes. Toll-like receptors have a crucial role in the detection of microbial infection in mammals and insects. In mammals, they have evolved to recognize conserved products unique to microbial metabolism. These include lipopolysaccharide (LPS), lipotechoic acids, and peptidoglycans (PGN). We show here that TLRs, including TLR2, are expressed on the THP-1 human leukemia cell line. Activation of TLR2 signaling in THP-1 by PGN induces the synthesis of various soluble factors and proteins including interleukin-$1{\beta}$, interleukin-8 and TNF-${\alpha}$ and apoptosis of THP-1 with PGN dose and time dependence. Moreover, in this study we show that PGN induces apoptosis of THP-1 cells in a TNF-${\alpha}$-dependent manner. These findings indicate that TLR2 signaling results in a cascade leading to tumor apoptosis and differentiation, which may suggest new clinical prospects using TLR2 agonists as cytotoxic agents in certain cancers.

Leaky-Wave Antennas Based on Noncutoff Substrate Integrated Waveguide Supporting Beam Scanning From Backward to Forward

Yue-Long Lyu,Xiao-Xin Liu,Peng-Yuan Wang,Erni, Daniel,Qun Wu,Cong Wang,Nam-Young Kim,Fan-Yi Meng Institute of Electrical and Electronics Engineers 2016 IEEE transactions on antennas and propagation Vol.64 No.6

<P>In this paper, we propose an approach to realize substrate integrated waveguide (SIW)-based leaky-wave antennas (LWAs) supporting continuous beam scanning from backward to forward above the cutoff frequency. First, through phase delay analysis, it was found that SIWs with straight transverse slots support backward and forward radiation of the -1-order mode with an open-stopband (OSB) in between. Subsequently, by introducing additional longitudinal slots as parallel components, the OSB can be suppressed, leading to continuous beam scanning at least from -40 degrees through broadside to 35 degrees. The proposed method only requires a planar structure and obtains less dispersive beam scanning compared with a composite right/left-handed (CRLH) LWA. Both simulations and measurements verify the intended beam scanning operation while verifying the underlying theory.</P>

Fusion Between TMPRSS2 and ETS Family Members (ERG, ETV1, ETV4) in Prostate Cancers from Northern China

Wang, Jian-Jiang,Liu, Yue-Xin,Wang, Wei,Yan, Wei,Zheng, Yu-Peng,Qiao, Lu-Dong,Liu, Dan,Chen, Shan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

In this study we evaluated the frequency of fusion between TMPRSS2 and ETS family members (ERG, ETV1, ETV4) in prostate cancers in patients from northern China in order to explore differences in fusion rates among regions in northern and southern China, other parts of Asia, Europe, and North America. We examined 100 prostate cancer patients, diagnosed by means of prostate biopsy; fluorescence in situ hybridization (FISH) was used to detect the expression of TMPRSS2, ERG, ETV1 and ETV4 in cancer tissue. Differences in gene fusion rates among different ethnics groups were also analyzed. Of the 100 prostate cancer patients, 55 (55%) had the fusion gene. Among the patients with the fusion gene, 46 (83.6%) patients had the TMPRSS2:ERG fusion product, 8 (14.8%) patients had TMPRSS2:ETV1 fusion, 1 (1.6%) patient had TMPRSS2:ETV4.

Human Papillomavirus (HPV) Infection in Women Participating in Cervical Cancer Screening from 2006 to 2010 in Shenzhen City, South China

Wang, Yue-Yun,Li, Li,Wei, Sheng,Peng, Ji,Yuan, Shi-Xin,Xie, Jian-Sheng,Liu, Zhi-Hua Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

Purpose: Human papillomavirus (HPV) infection plays an important role in the development of cervical cancer, but the prevalence of HPV infection in women of Shenzhen city remains unclear. The present study was performed to describe the change of cervical HPV infection in females who participated in voluntary cervical cancer screening from 2006 to 2010 in Shenzhen city, China. Methods: A total of 4, 413 women were recruited. HPV infections were genotyped by polymerase chain reaction (PCR) and reversed dot blot hybridization in Shenzhen Maternity and Child Health Hospital. Results: The prevalence of HPV infection was 13.8%. The five most commonly found HPV types were HPV16 (3.47%), HPV58 (1.68%), HPV33 (1.38%), HPV43 (1.36%) and HPV18 (1.27%). The secular trends of major HPV type-specific were diverse. Among of them, the prevalence of HPV18 increased sharply while others increased slowly or even decreased in the period. The change of total HPV, single HPV and multiple HPV infection were similar during the five years. Conclusions: Our findings suggested that HPV infection is common with HPV16 and HPV 58 as the primary subtypes in women in Shenzhen city.The prevalence of HPV 18 infection is increasing faster than any others, which will lead it to be one of the main subtypes in this city in the future.