The Correlation between Flexi-bar Exercise and Trunk Muscles Strength and Body Composition in Juvenile Soccer Players

Wang, Joong San,Park, Si Eun,Shin, Hee Joon,Choi, Wan Suk,Kim, Hong Rae,Kim, Bo Kyoung,Park, Joo Hyun,Lee, Joon Hee,Min, Kyung Ok International Academy of Physical Therapy Research 2015 Journal of International Academy of Physical Ther Vol.6 No.1

The purpose of this study is to verify a correlation between flexi-bar exercise and improvement of trunk strength and body composition in juvenile soccer players. The subjects were 11 teenager juvenile soccer players who conducted flexi-bar exercise half an hour daily three times a week for eight weeks. They were tested for trunk muscles strength, body composition and correlation. The result showed that trunk muscles strength improved significantly(p<.01) and weight, Rt. arm muscle mass, Rt. leg muscle mass, and Lt. leg muscle mass(p<.05), Lt. arm muscle mass, trunk muscle mass, and body muscle mass(p<.01) improved significantly as well while Lt. arm fat mass, Rt. leg fat mass, and Lt. leg fat mass decreased significantly(p<.05). In the correlation analysis, the more trunk muscle mass and trunk muscles strength increased, the more muscle mass of body regions increased, which was a positive correlation whereas fat mass of body regions decreased, which was a negative correlation. It was verified that there was a correlation between flexi-bar exercise and improvement of trunk muscles strength and body composition for juvenile soccer players.

Removal of nitrate from constructed wetland in winter in high-latitude areas with modified hydrophyte biochars

Bo Wang,Si-yao Liu,Fayun Li,Zhiping Fan 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.3

In high-latitude areas, nitrate treatment from constructed wetlands is often not so good in winter. The study aims to develop an efficient and economic technology to remove nitrate from constructed wetland under the conditions of winter temperature. We conducted laboratory experiments to investigate the removal of nitrate from aqueous solution and wastewater by modified hydrophyte biochars from constructed wetlands. The second-order model fit the nitrate desorption kinetics of modified hydrophyte biochars with a high coefficient of determination (R2>0.99). Freundlich isotherms performed well to fit the nitrate sorption data (R2>0.98) of modified hydrophyte biochars. Batch adsorption experiments also showed that both initial solution pH and coexisting anions could affect the adsorption of nitrate onto modified hydrophyte biochars. Our results suggested that modified hydrophyte biochars might be a promising alternative wastewater treatment technology for nitrate removal from constructed wetland in winter in high-latitude areas.

Polymorphisms in TYMS for Prediction of Capecitabine-Induced Hand-Foot Syndrome in Chinese Patients with Colorectal Cancer

Si-Qi Dong,Tong-Min Wang,Jiang-Bo Zhang,Yong-Qiao He,Wen-Qiong Xue,Zi-Yi Wu,Da-Wei Yang,Lian-Jing Cao,Jing-Wen Huang,Xi-Zhao Li,Pei-Fen Zhang,Xiao-Hui Zheng,Wei-Hua Jia 대한암학회 2021 Cancer Research and Treatment Vol.53 No.3

Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate synthase (TYMS) plays a key role for 5-fluorouracil metabolism and has been associated with some side effects caused by capecitabine. The aim of our study is to identify the possible genetic predictors of capecitabine-induced HFS (CAP-HFS) in Chinese colorectal cancer patients.Materials and Methods Whole exons of TYMS were sequenced for 288 extreme phenotype HFS patients, including 144 severe or early-onset (first 2 cycles) moderate HFS extreme cases and 144 extreme controls with no reported HFS. The associations between polymorphisms and CAP-HFS were analyzed using logistic regression under an additive model.Results We identified a novel risk mutation (c.1A>G, chr18:657743), was associated with severe HFS in an extreme case who was affected during the first cycle of treatment. Moreover, we identified three new variants, rs3786362, rs699517, rs2790, and two previously reported variants, 5’VNTR 2R/3R and 3′-untranslated region 6-bp ins-del, which were significantly associated with CAP-HFS (p < 0.05). In silico analysis revealed that the effect of these polymorphisms in the TYMS region on the development of HFS might not be restricted solely to the regulation of TYMS expression, but also the TYMS catalytic activity through the indirect effect on ENOSF1 expression.Conclusion This study identified new polymorphisms in TYMS gene significantly associated with CAP-HFS, which may serve as useful genetic predictors for CAP-HFS and help to elucidate the underlying mechanism of HFS.

Micro Convexity Elimination of Tungsten Carbide in Electrical Discharge Milling for Lens Moulds

Tianfeng Zhou,Si-Bo Wang,Xin Liu,Zhi-Qiang Liang,Xibin Wang 한국정밀공학회 2017 International Journal of Precision Engineering and Vol.18 No.12

Electrical discharge milling (ED milling) using spherical electrode is considered to fabricate tungsten carbide (WC) lens moulds for high volume and cost efficient mass production comparing with hemispherical electrode whose wear is noticeably larger. However, micro convexity with dome shape generating in the center of the mould leads to poor surface quality of moulds when using spherical electrode. Therefore, based on boundary layer theory, the forming mechanism of the micro convexity is analyzed in detail by measuring its height and profile by virtue of 3D laser scanning microscope and scanning electron microscope (SEM). The relationship between the boundary layer thickness and the discharge gap is subsequently established, which can be utilized to reduce the convexity to improve the surface quality of lens mould. Then a method to eliminate the micro convexity is proposed. In addition, experiments of different discharge gaps were carried out to confirm the boundary layer theory. Results show that the height of micro convexity can be reduced to 4 μm when the discharge gap was specified to the boundary layer thickness at certain rotational speed.

The Correlation between Flexi-bar Exercise and Trunk Muscles Strength and Body Composition in Juvenile Soccer Players

Joong San Wang,Si Eun Park,Hee Joon Shin,Wan Suk Choi,Hong Rae Kim,Bo Kyoung Kim,Joo Hyun Park,Joon Hee Lee,Kyung Ok Min 국제물리치료학회 2015 Journal of International Academy of Physical Ther Vol.6 No.1

Juvenile soccer players, Flexi-bar, Trunk muscles strength, Body composition The purpose of this study is to verify a correlation between flexi-bar exercise and improvement of trunk strength and body composition in juvenile soccer players. The subjects were 11 teenager juvenile soccer players who conducted flexi-bar exercise half an hour daily three times a week for eight weeks. They were tested for trunk muscles strength, body composition and correlation. The result showed that trunk muscles strength improved significantly( p<.01) and weight, Rt. arm muscle mass, Rt. leg muscle mass, and Lt. leg muscle mass(p<.05), Lt. arm muscle mass, trunk muscle mass, and body muscle mass(p<.01) improved significantly as well while Lt. arm fat mass, Rt. leg fat mass, and Lt. leg fat mass decreased significantly(p<.05). In the correlation analysis, the more trunk muscle mass and trunk muscles strength increased, the more muscle mass of body regions increased, which was a positive correlation whereas fat mass of body regions decreased, which was a negative correlation. It was verified that there was a correlation between flexi-bar exercise and improvement of trunk muscles strength and body composition for juvenile soccer players.

Functional significance of cholesterol metabolism in cancer: from threat to treatment

Xiao Mingming,Xu Jin,Wang Wei,Zhang Bo,Liu Jiang,Li Jialin,Xu Hang,Zhao Yingjun,Yu Xianjun,Shi Si 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

Cholesterol is an essential structural component of membranes that contributes to membrane integrity and fluidity. Cholesterol homeostasis plays a critical role in the maintenance of cellular activities. Recently, increasing evidence has indicated that cholesterol is a major determinant by modulating cell signaling events governing the hallmarks of cancer. Numerous studies have shown the functional significance of cholesterol metabolism in tumorigenesis, cancer progression and metastasis through its regulatory effects on the immune response, ferroptosis, autophagy, cell stemness, and the DNA damage response. Here, we summarize recent literature describing cholesterol metabolism in cancer cells, including the cholesterol metabolism pathways and the mutual regulatory mechanisms involved in cancer progression and cholesterol metabolism. We also discuss various drugs targeting cholesterol metabolism to suggest new strategies for cancer treatment.

Molecular cloning of the duck MEF2C gene cDNA coding domain sequence and its expression during fetal muscle tissue development

Ling-Li Sun,He-he Liu,Hao-han Wang,Jian-Ming Si,Hai-bo Jin,Xin-xin Li,Chao Yang,Liang Li,Jiwen Wang 한국유전학회 2013 Genes & Genomics Vol.35 No.3

Myogenic enhancer transcription factor 2c (MEF2c), one of the members of the MEF2 family of transcription factors, plays an important role in mammalian muscle development. However, the role of MEF2c in avian muscle development still remains unclear. To understand the function of MEF2c in avian muscle development, we first cloned the duck MEF2c coding domain sequence (CDS) and analyzed MEF2c expression in duck muscle tissues of embryos from 10 days of incubation to 1 week after birth using real-time PCR technology. The results showed that the duck MEF2c CDS consists of 1,398nucleotides that encode 465 amino acids. The MEF2c duck protein contains a MADS domain, a MEF2 domain and a HJURP_C domain with high homology to related proteins in other organisms. Different expression levels of MEF2c were found in skeletal, smooth and cardiac muscle. Therefore, these results indicated that duck MEF2c has two conserved domains (a MADS and a MEF2 domain), is an indispensable regulator of muscle development, and plays an important role in the development of duck muscle.

Effects of dietary Enteromorpha powder on reproduction-related hormones and genes during the late laying period of Zi geese

Ma Wei Qing,Zhao Dan Hua,Cheng Huang Zuo,Wang Si Bo,Yang Ji,Hong Xia Cui,Lu Ming Yuan,Wu Hong Zhi,Xu Li,Liu Guo Jun 아세아·태평양축산학회 2021 Animal Bioscience Vol.34 No.3

Objective: The aim of this study was to investigate the effects of Enteromorpha powder supplementation on reproduction-related hormones and genes in the late laying period of Zi geese. Methods: A total of 312 (1-year-old) Zi geese with similar laying rate were randomly divided into 2 groups with 6 replicates each, each with 21 female geese and 5 male geese. The control group was fed with a basal diet and the test group was fed with a diet containing 3% Enteromorpha powder. The trial period lasted for 7 weeks. Results: Our results showed that the laying rate was improved in the test group at each week of trial (p<0.01), and the levels of estradiol in serum and prolactin in ovary were increased compared with the control group (p<0.05). Conclusion: Based on above results, Enteromorpha powder supplementation at 3% could promote reproductive performance during the late laying period of Zi geese. Objective: The aim of this study was to investigate the effects of Enteromorpha powder supplementation on reproduction-related hormones and genes in the late laying period of Zi geese.Methods: A total of 312 (1-year-old) Zi geese with similar laying rate were randomly divided into 2 groups with 6 replicates each, each with 21 female geese and 5 male geese. The control group was fed with a basal diet and the test group was fed with a diet containing 3% <i>Enteromorpha</i> powder. The trial period lasted for 7 weeks.Results: Our results showed that the laying rate was improved in the test group at each week of trial (p<0.01), and the levels of estradiol in serum and prolactin in ovary were increased compared with the control group (p<0.05).Conclusion: Based on above results, <i>Enteromorpha</i> powder supplementation at 3% could promote reproductive performance during the late laying period of Zi geese.