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      • SCOPUS

        Hybrid Patterns Recognition of Control Chart Based on WA-PCA-PSO-SVM

        Liu Yan-zhong,Zhang Hong-lie,Liu Yan-ju,Jiang Jin-gang 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.10

        Based on the analysis of the defect of traditional model, this paper proposes a new control chart pattern recognition model, which includes Wavelet Analysis (WA), Principal Component Analysis (PCA), Particle Swarm Optimization (PSO) and Support Vector Machine (SVM). WA is good to eliminate noise control chart anomaly pattern recognition of the adverse effect. PCA eliminates the redundant information of data between SVM and reduces the input dimension and computational complexity. PSO algorithm optimizes the parameters of SVM and the establishment of the optimal control chart anomaly pattern classifier can solve the problem optimal parameters of SVM. The simulation results show that the model is feasible, the results are reliable. This algorithm improves the control chart abnormal state average recognition accuracy and be used in the machining process real-time monitoring.

      • KCI등재SCOPUS

        FRACTAL ANALYSIS FOR FRACTURE PROCESS OF ROLYMER MATERIALS

        Liu, Liu, Xiaobo,Gu, Gu, Yi,Jiang, Jiang, Luxia,Cai, Cai, Xingxian 한국재료학회 1995 Fabrication and Characterization of Advanced Mater Vol.1 No.3

        This work focuses on fractal analysis for fracture process of polymer materials in theoric model and experimental ditermination. A series of theoric fractal model based on fracutred surface for fracutre process of polymer materials are founded, and the fractal dimension of fractured surface wa obtained under various break mechanism including crack in shear bands, crack development in stonely wave, crack cross, break in brittle, fractured pocess for the rigid filtered polymers and self-reinforced liquid crystal thermotes. These results retlected that the bigger the fractal dimensiion of the fractured surface, the higher the toughenss of polymer materials. According to Griffith strength, the mechanical properties of polymers increased lindarly with the rise of fractal dimension value.

      • Conformational Transitions of Polymer Brushes for Reversibly Switching Graphene Transistors

        Liu, Song,Jamali, Safa,Liu, Qingfeng,Maia, Joao,Baek, Jong-Beom,Jiang, Naisheng,Xu, Ming,Dai, Liming American Chemical Society 2016 Macromolecules Vol.49 No.19

        <P>We developed a facile, but efficient, approach to graphene field-effect transistors (FET) functionalized with polymer brushes, in which the conductance can be reversibly switched by solvent-induced polymer conformational changes. Our experimental and stimulation results demonstrated that the solvent-induced conformational transition of the polymer brush could affect the carrier concentration by changing the number of,scattering sites associated with the graphene-polymer contact areas, leading to reversible electrical switching for the graphene FET device. Both end-adsorbed diblock and triblock copolymers showed similar switching effect through the solvent-induced chain stretching-collapse and tail-to-loop conformational changes, respectively. This work provides new platform technologies for developing novel electronic devices with tunable electrical properties and for studying macromolecular conformations and conformational transitions.</P>

      • SCIESCOPUSKCI등재

        Applicability research of round tube CHF mechanistic model in rod bundle channel

        Liu, Wei,Peng, Shinian,Shan, Jianqiang,Jiang, Guangming,Liu, Yu,Deng, Jian,Hu, Ying Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.2

        In view of the complex geometric structure of the rod bundle channel and the limitation of the current CHF visualization experiment technology, it is very difficult to obtain the rod bundle CHF mechanism directly through the phenomenon of the rod bundle CHF visualization experiment. In order to obtain the applicable CHF mechanism assumption for rod bundle channel, firstly, five most representative DNB type round tube CHF mechanistic models are obtained with evaluation and screening. Then these original round tube CHF mechanistic models based on inlet conditions are converted to local conditions and coupled with subchannel analysis code ATHAS. Based on 5 × 5 full-length rod bundle CHF experimental data independently developed by Nuclear Power Institute of China (NPIC), the applicability research of each model for CHF prediction performance in rod bundle channel is carried out, and the commonness and difference of each model are comparatively studied. The CHF mechanism assumption of superheated liquid layer depletion that is most likely to be applicable for the rod bundle channel is selected and two directions that need to be improved are given. This study provides a reference for the development of CHF mechanistic model in rod bundle channel.

      • KCI등재

        Optimization of Wavefront Coding Phase Mask Applied to 5X-40X Micro-Objectives Simultaneously

        Jiang Liu,Erlong Miao,Yongxin Sui,Jianghuai Yang 한국광학회 2015 Current Optics and Photonics Vol.19 No.5

        A wavefront coding (WFC) technique provides an extension of the depth of field for a microscopyimaging system with slight loss of image spatial resolution. Through the analysis of the relationship betweenthe incidence angle of light at the phase mask and the system pupil function, a mixing symmetrical cubicphase mask (CPM) applied to 5X-40X micro-objectives is optimized simultaneously based on point-spreadfunction (PSF) invariance and nonzero mean values of the modulation transfer function (MTF) near thespatial cut-off frequency. Optimization results of the CPM show that the depth of field of thesemicro-objectives is extended 3-10 times respectively while keeping their resolution. Further imagingsimulations also prove its ability in enhancing the defocus imaging

      • KCI등재

        High Speed Abrasive Electrical Discharge Machining of Particulate Reinforced Metal Matrix Composites

        Jiang-Wen Liu,Yong-Zhong Wu,Tai-Man Yue 한국정밀공학회 2015 International Journal of Precision Engineering and Vol. No.

        A high speed abrasive electrical discharge machining (AEDM-HS) process has been developed to improve the performance and save the machining energy of the conventional EDM process in machining particulate reinforced metal matrix composites (MMCs). The AEDM-HS process functions under a combined action of spark erosion and direct mechanical grinding. A set of experiments was conducted and the results showed that the material removal rate (MRR) of AEDM-HS was much higher than that of EDM under the experimental conditions of this study. Moreover, the surface roughness value (Ra) measured for the AEDM-HS specimen was about six times smaller than that of the specimen machined without high speed abrasive action (i.e., EDM alone). The material removal mechanism of this novel process has been analyzed by means of single-pulse experimentation. And the relative importance of the various processing parameters on MRR was established using orthogonal analysis. The results showed that the MRR is influenced by the machining factors in the order of duty cycle > current > pulse duration. This study showed that the AEDM-HS process is superior to the EDM process for machining particulate reinforced MMCs, where a higher machining efficiency and a better surface quality can be obtained.

      • KCI등재

        A New ent-Kaurane type Diterpenoid Glycoside from Inula japonica Thunb

        Jiang Jiang Qin,Jia Xian Zhu,Wei Dong Zhang1,2,Yan Zhu,Jian Jun Fu,Xiao Hua Liu,Hui Zi Jin 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.10

        A new ent-kaurane type diterpenoid glycoside, 17-O-β-D-glucopyranosyl-16α-ent-kauran-19-oic acid (1), together with 17-hydroxy-16α-ent-kauran-19-oic acid (2), 16α,17-dihydroxyl-ent-kauran-19-oic acid (3), and 16α-hydroxy-17-acetoxy-ent- kauran-19-oic acid (4) were isolated from the aerial parts of Inula japonica Thunb. The structure of 1 was determined mainly by use of 1D and 2D NMR spectroscopic techniques including HSQC, 1H-1H COSY, HMBC, and NOESY. In addition, 4 exhibited significant inhibitory activity on NO production in LPS-stimulated RAW264.7 cells with IC50 value of 14.3 μg/mL.

      • KCI등재

        Esomeprazole magnesium enteric-coated pellet-based tablets with high acid tolerance and good compressibility

        Jiang‑Yan Liu,Xiao‑Xue Zhang,Hao‑Yan Huang,이범진,Jing‑Hao Cui,Qing‑Ri Cao 한국약제학회 2018 Journal of Pharmaceutical Investigation Vol.48 No.3

        The aim of this study was to develop esomeprazole magnesium (EMZ-Mg) enteric-coated pellets and pellet-based tablets, as well as to investigate the effects of pellet size and compression method on acid tolerance, content uniformity, compressibility, and stability of preparations. This study used two types of pellet cores, namely, microcrystalline cellulose (MCC) core with a particle size of 150–300 μm and sucrose core with a particle size of 600–700 μm. Enteric-coated pellets, which consisted of a drug-free core, a drug layer, a sub-coating layer (hydroxypropyl methylcellulose, 6 cps), and an enteric-coating layer ( Eudragit®L30D-55), were prepared by using a bottomspray fluidized bed-coating technique. Pellet-based tablets were prepared by using a direct compression method or a wet granulation method. The acid tolerances of the two types of enteric-coated pellets (MCC and sucrose cores) reached up to 98% in simulated gastric fluid (pH 1.0) within 2 h, and the dissolution rates in simulated intestinal fluid (pH 6.8) reached up to 85% of the labeled amount within 15 min. When compressed into tablets, the pellets based on MCC core (smaller particle size) displayed a significantly higher acid tolerance (up to 92%) compared with the pellets based on sucrose core (larger particle size). In addition, the MCC core-based tablets (F8), especially those prepared by using a granulation method, showed higher drug content uniformity and compressibility than the sucrose core-based tablets (F10), and no lamination phenomenon was observed during compression. The crystallinity of EMZ-Mg was altered during drug layering process, and some physicochemical interactions were observed between the drug and excipients. Moreover, the two types of enteric-coated pellets showed a relatively high stability after storage under high temperature and strong light. However, they showed poor stability under high humidity, resulting in remarkable degradation of active compound. The EMZ-Mg entericcoated pellets and pellet-based tablets were successfully developed, and reduction in pellet size and wet granulation reduced the differences in content uniformity and better protected the pellet coating from damages during compression.

      • KCI등재

        A High Efficiency Two-stage Inverter for Photovoltaic Grid-connected Generation Systems

        Jiang Liu,Shanmei Cheng,Anwen Shen 전력전자학회 2017 JOURNAL OF POWER ELECTRONICS Vol.17 No.1

        Conventional boost-full-bridge and boost-hybrid-bridge two-stage inverters are widely applied in order to adapt to the wide dc input voltage range of photovoltaic arrays. However, the efficiency of the conventional topology is not fully optimized because additional switching losses are generated in the voltage conversion so that the input voltage rises and then falls. Moreover, the electrolytic capacitors in a dc-link lead to a larger volume combined with increases in both weight and cost. This paper proposes a higher efficiency inverter with time-sharing synchronous modulation. The energy transmission paths, wheeling branches and switching losses for the high-frequency switches are optimized so that the overall efficiency is greatly improved. In this paper, a contrastive analysis of the component losses for the conventional and proposed inverter topologies is carried out in MATLAB. Finally, the high-efficiency under different switching frequencies and different input voltages is verified by a 3 kW prototype.

      • Expression and Prognostic Significance of lncRNA MALAT1 in Pancreatic Cancer Tissues

        Liu, Jiang-Hua,Chen, Gang,Dang, Yi-Wu,Li, Chun-Jun,Luo, Dian-Zhong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

        Background: Long non-coding RNAs (lncRNAs) have been recently observed in various human cancers. However, the role of lncRNAs in pancreatic duct adenocarcinoma (PDAC) remains unclarified. The aim of this study was to detect the expression of lncRNA MALAT1 in PDAC formalin-fixed, paraffin embedded (FFPE) tissues and to investigate the clinical significance of the MALAT1 level. Methods: The expression of MALAT1 was examined in 45 PDAC and 25 adjacent non-cancerous FFPE tissues, as well as in five PDAC cell lines and a normal pancreatic epithelium cell line HPDE6c-7, using qRT-PCR. The relationship between MALAT1 level and clinicopathological parameters of PDAC was analyzed with the Kaplan-Meier method and Cox proportional hazards model. Results: The relative level of MALAT1 was significantly higher in PDAC compared to the adjacent normal pancreatic tissues (p=0.009). When comparing the MALAT1 level in the cultured cell lines, remarkably higher expression of MALAT1 was found in aspc-1 PDAC cells compared with the immortal pancreatic duct epithelial cell line HPDE6c-7 (q=7.573, p<0.05). Furthermore, MALAT1 expression level showed significant correlation with tumor size (r=0.35, p=0.018), tumor stage (r=0.439, p=0.003) and depth of invasion (r=0.334, p=0.025). Kaplan-Meier analysis revealed that patients with higher MALAT1 expression had a poorer disease free survival (p=0.043). Additionally, multivariate analysis indicated that overexpression of MALAT1, as well as the tumor location and nerve invasion, was an independent predictor of disease-specific survival of PDAC. Conclusion: MALAT1 might be considered as a potential prognostic indicator and may be a target for diagnosis and gene therapy for PDAC.

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