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      • Preparation of Titanium Microfiltration Membrane by Field-flow Fractionation Deposition

        Wang QiangBing,Tang HuiPing,Zhang QianCheng,Qiu QunFeng,Wang JianYong 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1

        The primary aim pursued by the preparation of separation membrane is the preparation of the membrane thin as well as with no defect. The field-flow fractionation deposition is a new molding technology which can overcome the traditional disadvantages such as multi-preparation to the preparation of great area of separation membrane with no defect. Therefor the mainly ingredients which influence the appearance and performance of titanium membrane layer are investigated by scanning electricity mirror (SEM) as well as porous material testing instrument: powder performance prepared and confected; selection of supporting body; sintering system such as temperature and time. It is shown that the membrane thickness can be controlled at or so; the filtration precision mainly rests with powder performance and selection of supporting body and little sintering system

      • KCI등재

        Spatial Distribution Patterns and Influencing Factors of PM2.5 Pollution in the Yangtze River Delta: Empirical Analysis Based on a GWR Model

        Wang Meixia,Wang Huiping 한국기상학회 2021 Asia-Pacific Journal of Atmospheric Sciences Vol.57 No.1

        Based on the PM2.5 concentration and economic and social data in the Yangtze River Delta during 2006–2016, the spatial distribution characteristics of PM2.5 pollution and the spatial heterogeneity of its influencing factors are analyzed using exploratory spatial data analysis and a geographically weighted regression model. The results show the following . The PM2.5 pollution situation is serious and presents a remarkable feature of spatial agglomeration in the Yangtze River Delta. Highly polluted areas are mainly concentrated in the northern cities of the Yangtze River Delta, while the air quality of the southern cities of the Yangtze River Delta is better. There is a significant positive spatial spillover effect of PM2.5 pollution in the Yangtze River Delta, which is to say that the air quality will be worsened by the PM2.5 pollution of surrounding cities . The influence coefficients of the population density, industrial proportion, car ownership and FDI on PM2.5 have spatial heterogeneity; that is, there are significant differences in their degrees of influence between different periods and cities.

      • KCI등재

        Physical, Chemical Properties and Structural Changes of Zaodan Pickled by Vacuum Decompression Technology

        Naxin Sun,Huiping Liu,Xiaowei Zhang,Hongni Wang,Shaojuan Liu,Pei Chen,Weijie Yu,Kai Liu 한국축산식품학회 2018 한국축산식품학회지 Vol.38 No.2

        To shorten the production cycle of Zaodan, this study first pickled Zaodan by a novel technology -vacuum decompression technology. Vacuum decompression technology could reduce the pickling time of Zaodan from 20wkto about 9wk.The protein content, moisture and pH of the Zaodan egg white gradually decreased with a concomitant increase in salt during the pickling process. The total sulfhydryl group (SH) group content of the egg white proteins was increased to 2.43×10-3mol/L after being pickled for 30 d, whereas the content of disulphide bonds (SS) was reduced to 23.35×10-3mol/L. The surface hydrophobicity was lowest after pickling for 30 d. In addition, great changes occurred in the secondary structure of the egg white proteins after pickling for 20 d. The disappearance of ovomucin was noticeable based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis.

      • KCI등재

        Concentration of polychlorinated biphenyls and risk assessment in finless porpoises from the East China Sea

        Chen Bingyao,Jiang Huiping,Wang Hui,Yang Guang,Hao Xiuqing 한국독성학회 2024 Toxicological Research Vol.40 No.2

        Polychlorinated biphenyls (PCBs) are bioaccumulative persistent organic pollutants with a great impact on cetaceans. To examine the content of PCBs and their risks to finless porpoises, this study determined the concentrations of seven typical PCB congeners in 56 tissue samples of East Asian finless porpoises (EAFPs) sampled in 2009–2012 from Ningbo (29.8835° N, 122.0644° E), Pingtan (25.5133° N, 119.8172° E) and Lvsi (32.1035° N, 121.6078° E). PCB138, PCB153 and PCB101 were the predominant congeners, accounting for 31.15%, 18.59% and 15.75%, respectively, of all PCBs detected. The content of PCBs increased with age in males but decreased from juveniles to adults in females due to transfer to calves by reproduction and lactation. EAFPs in Ningbo and Pingtan accumulated more PCBs than those in Lvsi Port. The trophic positions of EAFPs from Lvsi, Pingtan and Ningbo were 9.41, 8.95 and 9.43, respectively. PCB concentrations did not accumulate significantly with increasing trophic levels. The risk quotient index indicated that the risk of trichlorobiphenyl (3-PCB), tetrachlorobiphenyl (4-PCB), pentachlorobiphenyls (5-PCB), and hexachlorobiphenyls (6-PCB) to EAFPs in the East China Sea was generally low and within safe limits thus far.

      • SCOPUSKCI등재

        Direct Determination of Uric Acid in Human Serum Samples Using Polypyrrole Nanoelectrode Ensembles

        Yang, Guangming,Tan, Lin,Shi, Ya,Wang, Suiping,Lu, Xuxiao,Bai, Huiping,Yang, Yunhui Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.2

        Polypyrrole (PPy) nanotubes have been synthesized by chemical oxidative polymerization of pyrrole within the pores of polycarbonate membrane using the technology of diffusion of solutes. The nanotubes array prepared by the proposed method can be considered as nanoelectrode ensembles (NEEs). An amperometric uric acid sensor based on PPy NEEs has been developed and used for determination of uric acid in human serum samples. The electrode can direct response to uric acid at potential of 0.60V vs. SCE with wide linear range of $1.52{\times}10^{-6}\;to\;1.54{\times}10^{-3}\;M.\;The\;detection\;limit\;is \;3.02{\times}10^{-7}$ M. This sensor has been used to determine uric acid in real serum samples. PPy NEEs is thought of as a good application in the foreground.

      • KCI등재

        Modeling of a paper-making wastewater treatment process using a fuzzy neural network

        Mingzhi Huang,유창규,Jinquan Wan,Yan Wang,Yongwen Ma,Huiping Zhang,류홍빈,Zhanzhan Hu 한국화학공학회 2012 Korean Journal of Chemical Engineering Vol.29 No.5

        An intelligent system that includes a predictive model and a control was developed to predict and control the performance of a wastewater treatment plant. The predictive model was based on fuzzy C-means clustering, fuzzy inference and neural networks. Fuzzy C-means clustering was used to identify model’s architecture, extract and optimize fuzzy rule. When predicting, MAPE was 4.7582% and R was 0.8535. The simulative results indicate that the learning ability and generalization of the model was good, and it can achieve a good predication of effluent COD. The control model was based on a fuzzy neural network model, taking into account the difference between the predicted value of COD and the setpoint. When simulating, R was 0.9164, MAPE was 5.273%, and RMSE was 0.0808, which showed that the FNN control model can effectively change the additive dosages. The control of a paper-making wastewater treatment process in the laboratory using the developed predictive control model and MCGS (monitor and control generated system) software shows the dosage was computed accurately to make the effluent COD remained at the setpoint,when the influent COD value or inflow flowrate was changed. The results indicate that reasonable forecasting and control performances were achieved through the developed system; the maximum error was only 3.67%, and the average relative error was 2%.

      • KCI등재

        Direct Determination of Uric Acid in Human Serum Samples Using Polypyrrole Nanoelectrode Ensembles

        Guangming Yang,Lin Tan,Ya Shi,Suiping Wang,Xuxiao Lu,Huiping Bai,Yunhui Yang 대한화학회 2009 Bulletin of the Korean Chemical Society Vol.30 No.2

        Polypyrrole (PPy) nanotubes have been synthesized by chemical oxidative polymerization of pyrrole within the pores of polycarbonate membrane using the technology of diffusion of solutes. The nanotubes array prepared by the proposed method can be considered as nanoelectrode ensembles (NEEs). An amperometric uric acid sensor based on PPy NEEs has been developed and used for determination of uric acid in human serum samples. The electrode can direct response to uric acid at potential of 0.60V vs. SCE with wide linear range of 1.52×10-6 to 1.54×10-3 M. The detection limit is 3.02×10-7 M. This sensor has been used to determine uric acid in real serum samples. PPy NEEs is thought of as a good application in the foreground.

      • KCI등재

        FNC inhibits non-small cell lung cancer by activating the mitochondrial apoptosis pathway

        Jing Xiang,Niu Shuai,Liang Yi,Chen Huiping,Wang Ning,Peng Youmei,Ma Fang,Yue Wanying,Wang Qingduan,Chang Junbiao,Zhang Yi,Zhang Yan 한국유전학회 2022 Genes & Genomics Vol.44 No.1

        Background: Previously, we published that 4'-azid-2'-deoxy-2'-fluorarabinoside (FNC), a novel cytosine nucleoside analog, has good anti-viral and anti-tumor activity. Objective: This study aimed to further explore the role and molecular mechanism of FNC in non-small cell lung cancer (NSCLC). Methods: FNC was tested in the NSCLC H460 cell line, the Lewis mouse model, and the H460 cell xenograft model. The effects of FNC were assessed by cell viability, transwell migration, and wound scratch analyses of cell migration and invasion. Apoptosis was assessed by flow cytometry. Proteins expression was assessed by western blot and immunohistochemistry staining (IHC). Results: FNC inhibits the proliferation and metastasis of H460 cells in a time- and dose-dependent manner. FNC treatment showed efficacy and low toxicity in the Lewis mouse lung cancer model as well as in the H460 cell xenograft model. Further, FNC induced H460 cell apoptosis through the activation of the mitochondrial pathway. Notably, FNC inhibited invasion by increasing E-cadherin protein and reducing the protein expression of VEGF, MMP-2, MMP-9, and CD31. Conclusion: FNC inhibits NSCLC by activating the mitochondrial apoptosis pathway and regulating the expressions of multiple proteins related to cell adhesion and invasion, highlighting its potential as an NSCLC therapeutic.

      • A GA-Based Neural Fuzzy System for Modeling a Paper Mill Wastewater Treatment Process

        Huang, Mingzhi,Wan, Jinquan,Ma, Yongwen,Zhang, Huiping,Wang, Yan,Wei, Chaohai,Liu, Hongbin,Yoo, ChangKyoo American Chemical Society 2011 INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH - Vol.50 No.23

        <P>A genetic algorithm-based neural fuzzy system (GA-NFS) was presented for studying the coagulation process of wastewater treatment in a paper mill. In order to adapt the system to a variety of operating conditions and acquire a more flexible learning ability, the GA-NFS was employed to model the nonlinear relationships between the effluent concentration of pollutants and the chemical dosages, and a hybrid learning algorithm divided into two stages was proposed for parameters learning. During the first learning stage, a genetic algorithm was used to optimize the structure of GA-NFS and the membership function of each fuzzy term due to its capability of parallel and global search. On the basis of an optimized training stage, the back-propagation algorithm (BP algorithm) was chosen to update the parameters of GA-NFS to improve the system precision. The GA-NFS proves to be very effective in modeling coagulation perform and performs better than adaptive-network-based fuzzy inference system (ANFIS). RMSE, MAPE, and <I>R</I> between the predicted and observed values for GA-NFS were only 0.01099, 2.3337, and 0.9375, respectively.</P>

      • KCI등재

        Identifification and development of a core set of informative genic SNP markers for assaying genetic diversity in Chinese cabbage

        Peirong Li,Tongbing Su,Shuancang Yu,Huiping Wang,Weihong Wan,Yangjun Yu,Deshuang Zhang,Xiuyun Zhao,Changlong Wen,Fenglan Zhang 한국원예학회 2019 Horticulture, Environment, and Biotechnology Vol.60 No.3

        Rapid, economical, and reliable genotyping is an important requirement for germplasm analysis and cultivar identifi cationin crop species. Chinese cabbage ( Brassica rapa L. subsp. pekinensis (Lour.) Hanelt) originated in China and is now aneconomically important vegetable crop worldwide, especially in East Asia. In this study, we evaluated 1167 single nucleotidepolymorphisms (SNPs) among 166 representative Chinese cabbage inbred lines using a KASP genotyping assay. Onthe basis of polymorphisms and principal component analysis, we selected 60 core SNPs distributed on all Brassica rapachromosomes with allele frequencies suffi ciently balanced so as to provide adequate information for genetic identifi cation. The core set of SNPs was used for construction of a neighbor-joining dendrogram, in which the 166 inbred lines wereclustered into spring, summer, and autumn ecotype groups. Clustering of the ecotype groups was better resolved than thatachieved with 1167 and 360 polymorphic SNP datasets. Stability and resolution of the core SNP markers were tested using178 commercial hybrid Chinese cabbage cultivars to confi rm their utility in genetic identifi cation. The set of 60 informativeand stable SNP markers showed high discriminatory power and relatively uniform genomic distribution (4–9 markers perchromosome). The SNPs represent a cost-effi cient and accurate marker set for germplasm analysis and cultivar identifi cationand are suitable for molecular marker-assisted breeding in Chinese cabbage.

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