급성 백혈병 환자에서 수두양 피부병변을 보인 파종성 Fusarium 감염 1예와 국내 파종성 Fusarium 감염증에 대한 고찰

오수진,정희선,김준성,김태석,조병식,최수미,김명신,이연수,이석,신완식 대한감염학회 2007 감염과 화학요법 Vol.39 No.5

최근 면역저하환자의 증가와 함에 국내에서도 점차 침습성, 파종성 Fusarium 감염증 보고가 증가하고 있다. Fusarium 감염은 아스페르길루스 감염과 유사한 임상양상을 보이지만 특징적인 피부병변을 동반하고 혈액배양에서 균이 분리되는 경우가 더 많다. 저자들은 급성 림프구성 백혈병으로 진단받고 치료중인 30세 남자 환자에서 중증의 호중구 감소 상태에서 비특이적인 피부병변을 동반한 파종성 Fusarium 혈류감염을 경험하였기에 국내 증례 고찰과 함께 보고하는 바이다. 환자의 초기 피부병변은 구진에서 시작하여 주로 소포성 병변과 일부 통증을 동반한 결절 등 여러 형태로 나타났고, Tzank 도말검사 양성으로 비정형 수두로 오인되었다. 이후 피부병변은 농포로 변하였고, 혈액배양 및 피부 조직검사에서 파종성 Fusarium 감염으로 진단받았다. 환자는 liposomal amphotericin B, voriconazole 병합요법과 G-CSF 투여, 과립구 수혈을 받았으나, 호중구 감소증에서 회복하지 못하고 급성 호흡곤란증후군과 다장기 기능부전으로 사망하였다. 본 증례는 파종성 Fusarium 감염의 경우에도 수두양 병변으로 비특이적인 양상으로 나타날 수 있으므로, 감별진단을 위해 적극적으로 혈액배양과 피부조직검사를 시행해야 함을 보여준다. Recently, we experienced a case of disseminated fusarial blood stream infection with varicelloid skin eruptions, who had suffered from persistent neutropenic fever after salvage chemotherapy for relapsed acute lymphocytic leukemia (ALL). Neutropenia continued in spite of G-CSF and granulocyte transfusion, and he failed to respond to conventional amphotericin B initially, and then liposomal amphotericin B and voriconazole combination therapy. Disseminated fusariosis can be diagnosed by blood cultures in 50% of patients and present skin lesions in more than 80% of patients. So, typical skin lesions are important clue to diagnose of the disseminated fusariosis. However, many skin lesions in immunocompromised hosts are due to various infectious and non-infectious causes. So, this case shows that it is important to obtain biopsy specimens of skin lesions for histopathologic examination, culture and staining. Here, we present our case with the review of the literatures reported in our country, so far.

원자의 선택적 2광자 공명성 3광자 이온화 과정에 관한 밀도행렬의 수치해

오완영,남백일,강석찬,김영순 명지대학교자연과학연구소 1991 자연과학논문집 Vol.9 No.-

2광자 공명성 3광자 이온화 과정에서 밀도행렬의 시간에 대한 미적분방정식을 수치해 석적으로 계산하여 기저상태와 2광자 공명 여기상태의 전자밀도 행렬요소 σ??와 σ??,이온화율 P, 그리고 동위원소 선택율 S를 Li과 Sr원자들에 대하여 계산하였고, Rate Approximation에 기초한 준정상해의 결과와 비교하였다. 비교적 큰 동위원소이동 값을 갖는 ??Li와 ??Li의 경우 레이저의 세기가 매우 작은 영역과 큰 여역에서는 P와 s의 수치해의 계산결과와 준정상해법 계산결과는 비교적 잘 맞는 경향을 볼 수 있었으며, ??Sr와 ??Sr의 경우 즉, 동위원소 이동값이 700MH?에 불과한 경우 Li원자보다 민감하여 준정상해법의 결과는 제한적으로 적용됨을 볼 수 있었다. We present results of numerical calculations obtained through solving integro-differential equations for the electron density matrices ?? and?? and the ionization rate P in two-photon resonant three-photon ionization of Li and Sr, as well as the selectivity S for the isotope separation. We also compare our results with the predictions from quasi-stationary solutions based on the rate approximation. Our numerical results for P and S show that the quasi-stationary solutions are valid at very high and very low laser intensities when the isotope shift is large as in the case with 4s of ??Li and ??Li, and that the validity is rather limited in the cases with small isotope shift as in 5p? ?S of ??Sr and ??Sr.

소형엔진의 배출가스측정방법에 따른 질소산화물 및 매연에 관한 연구

한영출,나완용,오용석,문병철,박봉규,박귀열 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.3

Recently, increasing usage of diesel vehicle, many countries try to reduce the pollutant materials by emission regulation standard. Particularly, in our country, the supplement ratio of diesel vehicle is high, and air pollution by vehicle exhaust gas is very serious. So, in study, we tested exhaust gas by various mode in light duty diesel engine. Therefore, we can know about NOx and smoke seriousness.

대형디젤기관에 미치는 습윤식 에어 필터의 영향

김미수,나완용,오용석 한국공작기계학회 2004 한국생산제조학회지 Vol.13 No.3

Diesel engine offers superior fuel consumption than gasoline engine of equivalent capacity. For this reason, diesel engines are widely used in heavy duty transport applications. Specially, it has been many years that exhaust gases from gasoline automobile rather than from diesel is the major object concerned by Korea and other countries, and it strongly required on the reduction techniques on harmful NOx, Soot, CO, HC. thus, this paper focused on the emission reduction and target for this paper is heavy-duty diesel engine equipped with power filter such as wet type air cleaner. In this paper, the performance, exhaust emissions(CO, THC, Nox, Soot) and noise of heavy-duty diesel engine were measured at maximum load condition and the range of 1,000~2,200pm. The smoke was measured at FAS(Free Accel Smoke) test mode.

발아현미, 배양산삼 및 용안육 혼합 제제가 Pentobarbital로 유도된 수면시간에 미치는 영향

오석흥(Suk Heung Oh),오기완(Ki Wan Oh),조형권(Hyoung Kwon Cho),은재순(Jae Soon Eun) 한의병리학회 2010 동의생리병리학회지 Vol.24 No.4

Dynamic analysis and design of a high voltage circuit breaker with spring operating mechanism

Wan-Suk Yoo,Seung-Oh Kim,Jeong-Hyun Sohn 대한기계학회 2007 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.21 No.12

Spring Operating Mechanism (SOM) is a dynamic system to open and close the circuit breaker in a voltage control-ling system. For a high-speed action of opening and closing within a few mili-seconds, a SOM consists of many links, joints, chains, and cams. Thus, various dynamic characteristics are occurred, especially large contact forces between the cam and the roller, the shaft and the stopper. To save time and money for a new design of SOM system, analysis of the mechanism is necessary. In this paper, a multibody dynamic analysis and test technique was applied for a SOM to pre-dict, estimate and validate forces occurring during the operation. For the multibody dynamic analysis, the ADAMS program was employed for 145kV circuit breaker with a SOM. For an accurate modeling, several components were sequentially added and the reliability of modeling was validated through the comparison with test data of opening and closing.

Dynamic influence of patch size on occupancy of woodland birds

Suk, Ho Young,Chung, Ok-Sik,Lee, Jae-Young,Oh, Ki-Cheol,Lee, Wan-Ok,Jang, Gab-Sue 한국통합생물학회 2014 Animal cells and systems Vol.18 No.1

Throughout the long history of landscape ecology, scientists have devoted substantial efforts to understand potential forest patch size and isolation effects on the abundance and diversity of woodland species. Which bird species flourish or perish as a response to forest fragmentation may compose fundamental information for the reserve design and landscape management in a region. Here, we designed a bird survey of the urban forest areas in Dangjin city located on South Korea's west coast to test (1) if bird species richness follows the pattern predicted by species-area relationship and (2) if there is seasonal variation in the pattern. As expected, patch area was the most significant variable explaining patch occupancy of resident and summering woodland birds in every season. Our data about the number of dominant vegetation suggest that larger areas contain greater habitat heterogeneity and more diverse niches. About half of the resident species did not appear to be area-sensitive and were categorized as edge species. On the other hand, many summering species showed strong area-sensitivity, potentially avoiding small patches that are almost entirely edge habitats in urban landscape. Our results suggest that lots of contemporary forest edges, fragmented by agricultural or urban development, do not any more function for feeding or nesting places for those species.

HUVEC 세포에서 MMP-2 의 분비에 미치는 성장인자의 효과

오인숙,박종완,소상섭 全北大學校 科學敎育硏究所 2000 과학과 과학교육 논문지 Vol.25 No.-

Vascular endothelial cells release proteinase that degrade the extracellular matrix, thus enabling cell migration during angiogenesis and vasculogenesis. Endothelial cells secrete mainly the proform of matrix rnetalloproteinase-2. Matrix metalloproteinase-2 is Zn^2+ dependent protease produced by a variety of cell types. They have a fundamental role in tissue remodelling, tumour invasion and metastasis. The purpose of this study was to test if growth factors, such as angiopoietin-1, bFGF and VEGF can regulate the secretion of MMPs by endothelial cells. Of these growth factors, we found that VEGF is the strongest inducer of MMP-2 secretion. Both angiopoietin-1 and bFGF also induced the secretion of the MMP-2. VEGF induced MMP-2 secretion in a time- and dose-dependent manner. Pretreatment with phosphatidylinositol 3'-kinase inhibitors had no effect. NF-kB inhibitor, PDTC changed significantly the level of MMP-2 secretion from the cell. These results indicate that MMP-2 stimulates normal cell proliferation, wound healing and tissue remodelling in endothelial cells.

Bayesian analysis of financial volatilities addressing long-memory, conditional heteroscedasticity and skewed error distribution

Oh, Rosy,Shin, Dong Wan,Oh, Man-Suk The Korean Statistical Society 2017 Communications for statistical applications and me Vol.24 No.5

Volatility plays a crucial role in theory and applications of asset pricing, optimal portfolio allocation, and risk management. This paper proposes a combined model of autoregressive moving average (ARFIMA), generalized autoregressive conditional heteroscedasticity (GRACH), and skewed-t error distribution to accommodate important features of volatility data; long memory, heteroscedasticity, and asymmetric error distribution. A fully Bayesian approach is proposed to estimate the parameters of the model simultaneously, which yields parameter estimates satisfying necessary constraints in the model. The approach can be easily implemented using a free and user-friendly software JAGS to generate Markov chain Monte Carlo samples from the joint posterior distribution of the parameters. The method is illustrated by using a daily volatility index from Chicago Board Options Exchange (CBOE). JAGS codes for model specification is provided in the Appendix.

악안면 골격 형태에 따른 교합평면각의 변화에 관한 두부 방사선학적 연구

오세윤,김웅철,김지환,이준석,김진완,유진호,김태석 高麗大學校 倂設 保健大學 保健科學硏究所 1999 保健科學論集 Vol.25 No.1

A correlation analysis was made to understand the interaction between the growth patterns of some craniofacial skeletal components and occlusal plane inclination. 5 angular measurements(S.a. Ar.a, Go.a, UGo.a, LGo.a), 6 linear measurements(ACBL, PCBL, RH. MBL. AFH. PFH) and OP/SN. obtained from 83 cephalometric tracing records, were selected and the relationship between the occlusal plane angle and those measurements were analyzed statistically. Ramus Height(r=-0.55), Posterior Facial Height(r=-0.41), were found to be negatively related with Occlusal Plane angle, while Lower Gonial angle(r= 0.35), Saddle angle(r= 0.24) were found to be positively related with Occlusal Plane angle(p(0.05). The results obtained from the above analysis were further assessed with stepwise regression analysis, using Occlusal Plane angle as a dependant variable, and RH, LGo.a and S.a as explanatory variables. Stepwise regression analysis revealed that all the explanatory variables were found to be significant.(p<0.05) [OP/SN] = -8.74-0.33(RH)+0.23(S.a)+0.20(LGo.a). (R²=0.44). This stepwise regression analysis explains, to some extent, the relationship between the growth patterns of some craniofacial skeletal components and the occlusal plane inclination. 1. The inclination of Occlusal Plane angle is noticeably related with the growth patterns of some craniofacial skeletal components, i.e. RH, PFH, Saddle angle and Lower Gonial angle 2. In high Occlusal Plane angle, the Ram us Height tends to be shorter, and the Saddle angle and Lower Gonial angle tend to be obtuse.