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Peroxiredoxin V Regulates Aco2, Acadm, and Acox1 Activity in Hypoxic Kidney
Tae‐Hoon Lee,Hee‐Young Yang,Joseph Kwon,Hoon‐In Choi,Lina Ren,Ung Yang,Byung‐Ju Park,Zae Young Ryoo 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1
Peroxiredoxin V, an atypical thioredoxin peroxidase, is widely expressed in mammalian tissues. In addition, Prdx V is localized in mitochondria, peroxisome, cytosol, and nucleus. Prdx V has been reported to protect a wide range of cellular environments as antioxidant enzyme, and its dysfunctions may be implicated in several diseases, such as cancer, inflammation, and neurodegenerative disease. Identification and relative quantification of proteins affected by Prdx V may help identify novel signaling mechanisms that are important for oxidative stress response. However, the role of Prdx V in the modulation of hypoxia‐related cellular response is not studied yet. In order to examine the function of endogenous Prdx V in hypoxic condition in vivo, we generated a transgenic mouse model with Prdx V siRNA expression controlled by U6 promoter. Of many tissues, the knockdown of Prdx V expression was displayed in kidney, lung, and liver, but not spleen and skin. We conducted on the basis of nano‐UPLC‐MSE proteomic study to identify the Prdx V‐affected protein networks in hypoxic kidneys. In this study, we identified protein networks associated with oxidative stress, fatty acid metabolism, and mitochondrial dysfunction. Our results indicated that Prdx V affected to regulation of kidney homeostasis under hypoxia stress.
Kwon,Ki-Tae,Lee,Woo-Sik,Kwon,Lee-Seung,Seong,Seung-Hwan,Kim,Young-Do,Kwon,Woo-Taeg 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-
It is possible not only to treat high concentration organic matter such as food wastes but also to utilize food wastes as resources according to the bio-energy generation such as methane. The method of co-digestion of mixed wastewater mixed with organic wastes such as sewage sludge concentrated waters together with drinking wastewater is the most ideal method. Radiation not only has germicidal power in water treatment, but also is effective in decomposing degradable organic matter. Second chemical contamination problem is also solved because it does not use chemicals. Introduction of radiation pretreatment system to solve problems caused by mixing of waste water and organic waste resources. Biological electrochemical fusion system is used to remove the nutrients contained in the organic matter-removed mixture. Through the development of a system for treatment of high concentration wastewater, the processing efficiency is verified through the universal water treatment system for wastewater containing high concentration organic matter in addition to treatment of wastewater.
Developpe devant 수행시 하지 관절 모멘트 분석
박기자,신성휴,권문석,김태완,이형나 한국운동역학회 2004 한국운동역학회지 Vol.14 No.1
K. J. PARK, S. H. SHIN, M. S. KWON, T. H. KIM, H. N. LEE. Analysis on lower extremity joint moment during a developpe devant. Korean Journal of Sport Biomechanics, Vol. 14, No. 1, pp. 133-144, 2004. The purpose of this study was to analyze the joint moment on lower extremity during a developpe devant. Data were collected by Kwon3D, KwonGRF program. Two professional modem female dancers were participated in this experiment. Subjects performed a developpe devant in meddle heights. On the axes of X, Y, Z, it was shown that the maximum joint moment was occurred in hip joint. The moments are plotted during developpe devant. The ankle muscles generate a plantar flexion moment and the knee muscles generate a flexion moment and The hip muscles generate a extension moment. So these muscles of joint muscles were known to play a key role in keeping the body balance while doing developpe devant. In addition adduction moment occurred at hip, knee, an ankle in the order of amount, we could assume from this data that turn out motion started from the hip joint. There was small active turn out possible below the hip joint. A small amount of extra turn out could be obtained when standing because of flexion between the foot and floor, which could be used to give a passive external rotation force to the whole leg and this could produce a rotation between the knee and foot. This passive external rotation could produce very damaging results. Therefore, lower extremity joint muscles such as hip, knee, and ankle muscle should be trained to keep the body balance and prevent injury during developpe devant performance. And for the safe and perfect turn ort performance, hip joint abduction, the most important external rotating muscle for turn out is needed to train and full stretching should be done in advance.
사업장(事業場) 근로자(勤勞者)의 사상체질(四象體質)에 따른 생활습관(生活習慣), 자각증상(自覺症狀), 건강인식(健康認識)에 관(關)한 연구(硏究)
서명효,강홍구,장두섭,왕명자,차남현,김삼태,권소희,정해경,송용선,이기남,Seo Muoung-Hoy,Kang Hong-Goo,Jahng Doo-Sub,Wang Myoung-Ja,Cha Nam-Hyun,Kim Sam-Tae,Kwon So-Hee,Jung Hae-Kyoung,Song Yung-Sun,Lee Ki-Nam 대한예방한의학회 2003 대한예방한의학회지 Vol.7 No.2
The study was conducted to evaluate the difference of life style, subjective symptoms and health cognition depending on the Sasang Constitution in the industrial workers. The results were as follows ; Constitutional distribution among exposed group were Tae-eum In(38.4%), So-eum In(35.2%), and So-yang In(26.4%) and it was turned out that Tae-eum In took a higher portion of Sasang constitution than other constitutions in technician workers. 'Exercise' and 'Obesity' were found most in Tae-eum In, In So-eum In there were many 'Normal' weight and 'Having digestive disorders' were found most in So-eum In. There were no significant difference in the health cognition among the constitutions. The closer to 'normal' weight, the higher prevalence in 'having' concern about health condition and the more 'normal' condition in sleeping, the higher prevalence of 'having' self-confident in present health.
권태봉,이정선,우영국,이명헌,정철원,주진순 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.1
위암발증의 원인을 밝히기 위하여 설문조사를 통하여 강원도 화천군에 거주하는 주민들의 일반사항, 생활습관 및 영양섭취실태와, ELISA법으로 Helicobacter pylori 감염률을 조사하였다. 조사 대상자는 40∼69세까지의 지역주민 169명으로 남자 79명, 여자 90명이었으며 그 결과는 다음과 같다. 조사 대상자의 학력은 65.7%가 초등학교 이하였으며, 월수입은 60%가 50만원 이하였다. 대상자의 62.7%가 농업에 종사하였고 자녀수는 64.3%가 3∼5명이었으며 대상자의 34.5%가 흡연을 하고 있었고 68.4%가 음주를 한다고 대답하였다. 대상자의 전체 평균신장은 156.7㎝로 여자는 150.1㎝, 남자는 164.4㎝ 이었다. 평균체중은 61.1㎏으로 여자의 체중은 57㎏, 남자는 65.7㎏이었으며 BMI는 전체 평균 25.5%로 여자는 24.8%, 남자는 20.1%이었다. Helicobacter pylori의 감염률은 전체 조사대상자의 66.3%이었으며, 여자의 67.7%, 남자의 64.6%가 감염되었고 연령별로는 40대의 70%, 50대의 62.2%, 60대의 69.4%가 각각 감염된 것으로 나타났다. 일상 생활 요인에 따른 Helicobacter pylori의 감염률은 흡연의 정도가 심하고 학력이 낮으며 월수입이 낮을수록 높은 경향을 보였다. Helicobacter pylori의 감염여부에 따라 감염자와 비감염자의 영양섭취량을 조사해 본 결과 비감염자는 감염자와 비교해서 에너지, 총단백질, 동물성 단백질, 칼슘, 비타민 C 섭취량이 높은 경향을 보였으며 철분과 niacin의 섭취량은 낮은 경향을 보였다. To examine the relationship between the casual infection of gastric cancer and lifestyle and nutritional status, we surveyed 169 persons, 90 females and 79 males, aged 40∼69 years from June 7 to June 14, 1997, in Whachon area, Kang-Won Do, Korea. For this purpose, we investigated Helicobacter pylori infection and identified the effect of sex, age, smoking, alcohol consumption, economic status, occupation, life-style and food intake on Helicobacter pylori infection. Helicobacter pylori status was evaluated using an enzyme-linked immunosorbant assay(ELISA) for anti-Helicobacter pylori immunoglobulin G(IgG). Helicobacter pylori infection was present in 66.3% of total subjects, namely, 67.7% of female and 64.6% of male and its prevalence increased with smoking, low education level and low monthly income. Energy, total protein, calcium and vitamin C intakes in the negative Helicobacter pylori infection group were higher than those in positive Helicobacter pylori infection group. However iron and niacin intakes were lower in the Helicobacter pylori negative group than in the positive group.
부분적으로 유체가 채워진 원통형 관내의 외팔보 진동특성에 관한 실험적 연구
권대규,유계형,소순선,이성철 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2003 工學硏究 Vol.34 No.-
This paper presents the vibration characteristics of an intelligent cantilever beam in contact with fluid using PZT actuator and PVDF film. The effect of liquid level on free vibration of composite beam in a partially liquid-filled circular cylinder is investigated. The dynamic behaviors of a flexible beam-water interaction system are examined. The coupled system is subject to an undisturbed boundary condition in the fluid domain. In the vibration analysis of wetted beam, the decoupled analyses between beam and fluid have been conventionally employed by considering firstly the composite beam vibration in air and secondly performing the correction taking account for surrounding fluid effects. That is, this investigation was to look at how natural frequencies, mode shapes, and damping are affected by liquid level variations. Using the coupled modal reanalysis method employing the governing equations and the clamped-free and free-free boundary conditions, the vibration analysis of beam in contact with fluid is performed. We also carried out the experimental verification about reliability of theoretical methods to inclusive vibration analysis of the fluid-structure system with PZT actuator and PVDF film. It was found that the coupled natural frequencies decrease with the fluid level for the identical composite beam due to added mass effect.
이종갑,권태희,손홍규,김형태 大韓小兒齒科學會 1993 大韓小兒齒科學會誌 Vol.20 No.2
Upper cuspid impation is a serious that occurs with sufficient frequency to justify diagnosis and intervention as early as a dental age of 8 years. The maxillary cuspid follows a more difficult and tortuous path of eruption than other tooth. Where upper arch crowding prevents such a tooth from following its normal eruption path, it will diverted either buccally or palatally. The diagnosis of canine impaction is on both clinical and radiographic examinations. When clinician detects early signs of ectopic eruption of canines, an attempt should be made to prevent theier impaction and its potential sequelae. Screening consists of identifying patients who lack a normal cuspid bulge on palpation, with follow-up radiographic evaluation where indicated. Selective removal of deciduous cuspids is a suggested interceptive measure in class Ⅰ uncrowded malocclusions. Each patient with an impacted canine must undergo a comprehensive evaluation of the malocclusion. The clinician should then consider the various treatment options available for the patient. Surgical exposure of the canine and orthodontic treatment to bring the tooth into the line of occlusion is the most desirable approach. After the surgical exposure of the impacted tooth, an auxiliary(button) is attached to the crown. It should be reemphasized that in the surgical exposure of an impacted tooth, only enough bone should be removed to allow for the placement of a bracket and that during the procedure the CEJ should not be intentionally exposed. The removable appliance was designed This applied traction along a desired path of eruption using elastics changed daily Removable appliance seemed to offer more in vertical anchorage than did the fixed appliances. 13 year-old male and 14 year-old female with impacted maxillary canine were treated with surgical exposure and direct traction.