야쿠트어 폐쇄자음 연구-러시아어 차용어휘 분석-

강덕수 ( Duck Soo Kang ),김지선 ( Jee Sun Kim ),홍준희 ( Jun Hee Hong ) 한국외국어대학교 언어연구소 2007 언어와 언어학 Vol.0 No.39

Duck-soo Kang.Jee-sun Kim.Jun-hee Hong. 2007. A Study of Obstruents in Yakut through Analysis of Borrowed Words from Russian. Language and Linguistics 39, 1-16. One of the most important constraints in Yakut is connected with syllabic structure. Its syllabic structure is based on CV. So the constraint of "NoGeminates" is strictly applied. And the harmony between features is also considered important. Yakut has the strict constraint on the phonotactical relations. In Yakut a feature [constricted glottis] works more vigorously than [voiced]. This feature is combined with a feature [+back] or [+lab], making new constraints on the initial place: *#[+back, -CG], *# [+lab,+CG]. Finally, consonantal assimilation in obstruents of Yakut is dominated by 2 lows of constraints. VowelHarmony >> Ident-CV[pl] >> NCP >> *[+palatal]# >> Ident-IO; *#[+back, -cont][+back,-high] >> *#[+back,-CG], *# [+lab,+CG] >> [+cont] >> NoGem >> Ident-IO >> *[+voiced]#

악성흑색점흑색종 19예에 대한 임상 및 병리 조직학적 연구

홍원진 ( Won Jin Hong ),장홍선 ( Hong Sun Jang ),이상희 ( Sang Hee Lee ),이상은 ( Sang Eun Lee ),정기양 ( Kee Yang Chung ),노미령 ( Mi Ryung Roh ) 대한피부과학회 2016 大韓皮膚科學會誌 Vol.54 No.10

Background: Lentigo maligna melanoma (LMM) is a subtype of melanoma that typically develops on sun-damaged skin. LMM is estimated to comprise 4∼15% of melanomas, but the prevalence is known to be relatively lower in the Korean population than in the Caucasian population. Objective: To review the clinico-pathologic features and treatment outcomes of Korean patients with LMM. Methods: Nineteen patients diagnosed with LMM during 2003∼2015, in the Yonsei University Health System, were included in this study. The age and sex of the patients, lesion location, thickness (Breslow), stage, treatment methods, BRAF, NRAS, and KIT mutation status, and survival rates were analyzed. Results: Among the 19 Korean patients, 11 were male and 8 were female. The median age was 59.2 years. The most common site was the cheek (47.4%), followed by the scalp, eyelid, nose, forehead, lip, and neck. At the time of diagnosis, 13 patients were in localized stages (5 patients, stage 0; 3 patients, stage I; and 5 patients, stage II) and 6 patients were in advanced stages (3 patients, stage III; and 3 patients, stage IV). Patients in the localized stages showed better overall survival (OS) than those in the advanced stages (p=0.012). Nine patients were treated with a wide excision, and 6 using Mohs micrographic surgery. Three patients received high-dose interferon-α therapy; 6, chemotherapy; and 4, radiotherapy. Two patients in stage 0 were treated with topical ingenol mebutate. Two patients had BRAF V600E mutation; 1, NRAS G12R mutation; and 1, KIT mutation. Median OS of the patients was 40.8 months. Conclusion: Our analysis provides additional information about clinical characteristics, treatment, and prognosis of LMM in Korean patients. (Korean J Dermatol 2016;54(10):769∼775)

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

TRISOMY 9의 산전진단 1례

홍희선,박숙자,강경화 日新基督病院 1996 日新基督病院論文集 Vol.11 No.-

Flurescent In Situ Hybridization방법으로 분석한 소양호 세균 군집 구조의 졔절적 변화

홍선희,안태석 江原大學校 附設 環境硏究所 1998 環境硏究 Vol.15 No.-

소양호에서 세균군집의 계절적, 수심별 변화를 파악하고자 총세균수와 EUB338, ALF1b, BET42a, GAM42a와 CF probe 등 fluorescent rRNA targeted oHgonucleotide probe와 반응하는 세균 개체수를 측정하였다. 총세균수는 0.5~2.01×10^(4)cell·㎖이였으며, 2m와 5m 수층에서 높게 나타났다. 총세균수에 대한 Eubacteria의 비율은 22~100%였고 Proteobacteria α-group은 Eubacteria의 2.6~66.7%, β-group은 4.5~53.5%, γ-group은 4.6~7.6%, 그리고 Cylophaga-Flavobacterium group은 2.1~35.9%이였다. 또한 세균군집은 계절별, 수심별로 다양한 변화를 보여, 겨울철을 β-group이, 봄철과 초여름철은 γ-group이, 여름철은 α-group이 우점하였고, Cytophaga-Flavobacterium group이 특징적으로 우점하는 시기는 없었다. 이러한 세균 군집 구조의 분포로 계절별, 수심별로 호수에 대한 독특한 특징을 알 수 있었다. To define the structure and diversity of bacterial communities in the aqutic ecosystem, Lake Soyang, the largest artificial reservoir in Korea, a new method, fluorescent in situ hybridization was applied. This technique relies on the specific hybridization of the nucleic acid probes to the naturally amplified intracellular rRNA. By this method, the bacterial community composition of Lake Soyang and bacterial numbers belong to eubacteria, proteobacteria and Cytophaga-Flavobacteria group were estimated. Total bacterial numbers ranged from 0.3×10^(6)~2.O×10^(6)cells · ml^(-1), and vertical profile of total bacteria showed the peak at 2 and 5 m depths. The ratio of eu-bacteria to total bacteria were 22~100% and varied wuth depth and season. The percentage of Prothobacteria α-group ranged 2.6~66.7%, β-group 4.5~ 53.5%, γ-group 4.6~70.7% and Cytophaga-Flavobacterium group 2.1~35.9%. Also, bacterial community had spatial and temporal characteristics. The dominant groups were β-group in winter, γ-group in spring and early summer and α-group in summer.

인터넷 기반의 일상식품의 e-식품교환량(ENECC/E-Food Exchange)과 검색 시스템 개선

홍순명,조희선,김곤 대한영양사협회 2004 대한영양사협회 학술지 Vol.10 No.2

The food exchanges are frequently used to nutrition education and counseling for diabetes, weight control, hyperlipidema and etc. But it is difficult to find out food exchange lists with food exchange groups in the food composition table. This study was conducted to select e-food exchange of commonly used foods(456 foods) and improve search system based on internet. Also, the e-food exchange database was developed as having the proximate composition, mineral and vitamin content such as energy, moisture, protein, fat, carbohydrate, ash, calcium, phosphorus, iron, sodium, potassium, retinol equivalent, retinol, Pcarotene, thiamin, riboflavin, niacin, ascorbic acid, refuse per 100g of each food. The e-food exchange database developed is basically based on the 6th food composition table(2001) of the National Rural Living Science Institution in Rural Development Administration, Korea. The 456 commonly used foods or 2,262, all foods can be searched easily in a new system. A specific food of e-food exchange can be searched by a given set of food groups or food name and can give information about food one exchange lists, weight and nutrient value per lOOg of each food user-friendly on internet. It can be used to make a nutritionally balanced meal plan, nutrition education and counseling.

인터넷 기반의 식품 교환량 데이터베이스 구축과 검색 시스템 (ENECC/E-Food Exchange)에 관한 기초 연구

홍순명,조희선,김곤 대한영양사협회 2003 대한영양사협회 학술지 Vol.9 No.2

The food composition tables are frequently used to health and nutrition practices. But it is difficult to find out food exchange lists with food exchange groups in the food composition table. Over 2500 items and many kinds of nutrients are in the food composition table. But now food exchange lists are used a few foods. The internet demands the users needs for obtaining more food exchange lists and nutrient information from food composition. This basic study is to solve the users need and the supply more efficient and effective manipulation system for e-food exchange database construction and search system: ENECC/e-food exchange(E-Nutrition Education and Couseling Center/e-food exchange). This paper introduces the food exchange database construction and search system(ENECC/e-food exchange) using the formula which calculates the food exchange quantity of 6 food exchange groups and added one extra groups(alcohol) based on the internet. The ENECC/e-food exchange database is basically based on the 6th food composition table(2001) of the National Rural Living Science Institution in Rural Development Administration, Korea. The e-food exchange database are consisted of 2,261 foods in 6 basic food groups and one extra groups by using ENECC calculating formula. Also, the e-food exchange database has the proximate composition, mineral and vitamin content such as energy, moisture, protein, fat, carbohydrate, ash, calcium, phosphorus, iron, sodium, potassium, retinol equivalent, retinol, β-carotene, thiamin, riboflavin, niacin, ascorbic acid, refuse per 100g of each food. To calculate e-food exchange, ENECC/e-food exchange calculating formula was developed. The one food exchange weight and ENECC/e-food exchange weight were significantly correlated. It shows that the use of this formula is valuable and easily usable. A specific food of e-food exchange can be searched by a given set of food groups or food name and can get information about food one exchange lists, weight and nutrient value per 100g of each food user-friendly on internet. It can be used to make a nutritionally balanced meal plan and nutrition education and counseling.

장중첩증을 동반한 맹장 지방종 1예

홍의실,나병규,김민옥,유일영,채지영,채희복,윤세진,이상전,송형근,박길선,정현용 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.2

대장 지방종은 주로 우측 결장에 호발하고 특히 회맹판 부위와 맹장 부위에 호발한다. 또한 50~60대에 빈도가 높고 증상이 있는 환자에서 장중첩증이 높게는 40~50%에서 보고되고 있어 성인 장중첩증의 원인으로 중요한 비중을 차지한다. 특히 성인 장중첩증 및 장폐쇄의 중요 원인인 악성 종양과 임상 양상이 유사하여 감별진단이 중요하다. 저자들은 반복적인 복통을 주소로 내원한 환자에서 맹장의 4×5㎝의 점막하 지방종이 말단 회장부위와 반복적인 장중첩중이 발생했던 1례를 부분 절제술로 치료하여 양호한 임상 경과를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Lipomas are one of the most common benign nonepithelial tumors of the colon which are often detected incidentally by radiologic investigation or on operation. These tumors are usually without specific symptoms. Colonic lipomas occur most often in the right colon, particularly in the ileocecal valve and the cecum. Most patients are asymptomatic. but tumors larger than 2 cm tend to produce a change in bowel habit. abdominal pain. rectorrhagia and complications including luminal obstruction or intestinal intussusception. Diagnosis can be made by colonoscopy abdominal CT. MRI, or barium enema. We report a case of lipoma of the cecum that originated in the submucosa and presented as a intussusception in a 50-year-old woman with a brief review of the literature.

유아의 음악선호도 조사

홍지현,장선희 이화여자대학교 사범대학 교과교육연구소 2004 교과교육학연구 Vol.8 No.2

본 연구는 중ㆍ고등학생 및 대학생들의 음악양식에 대한 선호도를 파악하고 그 선호도에 미치는 연령,성별 그리고 곡에 대한 친숙도 요인들의 영향을 파악하는데 그 목적이 있다. 이를 위하여 서울의 중ㆍ고등학생 및 대학생 810명(중학생 303명, 고등학생, 284명, 대학생 223명)을 대상으로 5가지 음악양식(서양 클래식, 한국 대중음악, 재즈, 국악 록음악)에 대한 각 각 6곡 씩, 30곡에 대한 선호도와 친숙도를 검사하였다. 연구대상은 11세에서 33세까지의 남학생 378명, 여학생 432명으로 구성되었다. 음악선호도는 평균 37초 길이의 음악을 들고 선호도와 친숙도를 7점 리커드 척도에 표시하도록 하였고, 청취곡은 무작위로 순서를 배열한 두 가지형의 CD로 제작하여 사용함으로써 청취곡의 순서에 의하여 개별곡에 대한 선호도가 영향을 받는 것을 최소화 하고자 하였다. 음악양식 선호도에서는, 한국 대중음악을 가장 선호하였으며, 서양 클래식음악, 재즈, 그리고 록음악 순이었으며, 국악을 가장 덜 선호 하는 것으로 나타났다. 선호도와 친숙도는 모든 장르에서 양의 상관관계를 보이고 있으며 한국대중음악과 국악에서 가장 강한 상관관계를 보이고 있다. 성별에 따른 선호도는 여학생이 남학생보다 모든 장르에서 높은 선호도를 보이고 있으며, 특히 재즈와 국악에서 더욱 두드러진 결과를 보이고 있다. 중학생들의 선호도는 고등학생이나 대학생들에 비하여 낮았으며, 고등학생들의 선호도는 18세경까지는 지속적으로 증가하고 그 이후 대학생 연령층에서는 비교적 안정된 선호도를 형성하는 것으로 나타났다. 중학생들은 서양 클래식음악을 가장 선호하며, 고등학생들은 한국 대중음악 그리고 대학생들은 재즈음악이 가장 선호하는 양식으로 본 연구에서 조사되었다. 중다회귀분석결과, 선호도는 그 곡에 대한 친숙도에 의해 가장 잘 예견될 수 있으며 그 다음이 연령, 그리고 성별 순으로 나타났다. 국악장르의 청취곡들은 모두 잘 알려지고 교과서에 수록 된 곡들임에도 불구하고 선호도와 친숙도가 가장 낮은 장르로 나타나고 있으나 선호도는 18세부터 대학생 연령까지 지속적으로 상승하고 있었다. 본 연구의 결과는 미국에서 진행된 르불랑과 그의 동료들(1996)의 연구보다는 홍콩의 훵과 그의 동료들(2000)의 연구결과와 더 공통된 결과를 보이고 있다. 이것은 최근에 이루어지고 있는 비교 문화적 선호도 연구와 그 맥락을 같이 하는 것으로서 문화 배경적 선호도 연구경향에 대한 긍정적인 시사점을 제시하고 있다고 할 수 있다. This study is to investigate the music style preferences of secondary school and college students, and also to determine the effect of age, gender and familiarity on the music excerpts. A total of 810 students participated in the study and data were collected on their music style preference among Western classical music, Korean popular songs, Jazz, Korean Traditional Music and Rock Music. A. preference opinion form, with 30 music listening excerpts on CD was utilized. A seven-point preference scale was used for each listening excerpt. The participant (n=810) in the study ranged from age 11 to 33 years, and the gender ratio is 378 male ro 432 female students.. Results of multi regression showed that familiarity, age and gender had significant main effects (p<.01) on the style preference in general. The preference of female students was higher than male students in all six styles of music excerpts. The preferences tended to increase as the subjects age increased. Based on the results, the study has reached the following conclusions: First, Korean popular music was the most preferred music style, followed by Western Classical Music, Jazz, and Rock. Korean traditional music was the least preferred style. Significant changes in preference for all music styles generally occurred at about the age 18. Second, music style preferences differed by age and gender. Student aged12-14 years showed the lowest preference among the three students groups. High school students (age 15-18) showed the highest preference forKorean popular music as their most preferred style. College students (age 18 plus) demonstrated more stable preference tendency in all the music excerpts. Third, although the excerpts of Korean Traditional Music were selected from the textbooks used by junior and high school students, the students' familiarity level was very low. However, the preference for Korean traditional music showed the most dramatic increase of preference as their age increased.

16S와 23S rRNA에 결합하는 probe를 이용한 겨울철 소양호 세균 군집 구조의 분석

홍선희,변명섭,안태석 江原大學校 附設 環境硏究所 1998 環境硏究 Vol.15 No.-

겨울철 소양호에서 세균 군집 구조를 파악하고자 총세균수와 EUB338, ALF1b, BET4a, GAM42a와 CF probe등 fluorescent rRNA targeted oligonucleotide probe와 반응하는 세균 개체수를 수심별로 측정하였다. 총세균수는 0.7×10^(6)~1.1×10^(6)cell·㎖^(-1)이였으며, 5m와 10m 수층에서 높게 나타났다. 총세균수에 대한, Eubacteria의 비율은 34~90%이였으며, 5m와 10m에서 낮게 나타났다. Proteobacteria α-group은 Eubacteria의 10.8-28.7%, β-group은 4.5-53.5%, γ-group은 4.9-35.5%, 그리고 Cytophaga-Flavobacterium group은 6.1-21.1%이였다. 0.5m 수심에서는 β-group이 28.6-53.3%로 우점하고 있었으며, 10m에서는 γ-group이 35.5%로 우점하였다. 30, 50m 수심에서는 α-group과 Cytophaga-Flavobacterium group이 우점하였다. 세균 군집 구조로 보면 0-2m, 5-10m 그리고 30-50 m의 3개층은 각각 독특한 특징을 나타내었다. 이 방법으로 호수 생태계에 대한 새로운 정보를 얻을 수 있었다. To scrutinize the bacterial community composition of Lake Soyang in winter, bacterial numbers blonging to Eubacteria, Proteobacteria and Cytophaga-Flavobacterium group were estimated by using 16S and 23S rRNA targeted oligonucleotide probes. Total bacterial numbers ranged from 0.7Χ10^(6)~1.1Χ10^(6)cell ·㎖^(-1)and vertical profile of total bacteria showed a peak at 5m and 10m depths those were low exhibiting, 39 and 34%, respectively, The percentage of proteobacteria α-group ranged 10.8~28.7%, β-group 4.5~535%, Υ-group 4.9~35.5% and Cytophaga-Flavobacterum group 6.1~21.1%. The dominant groups were β-group at 0, 2 and 5m Υ-group at 10m, α-group at 30m and Cytophaga-Flavobacterium group at 50m depth. In winter season, Lake Soyang can be divided into into three layer, 0~2m, 5~20m and 30~50m, by bacteria community composition. By this method, new informations about aquatic ecostem were developed.