An Analysis of User Satisfaction of K University’s Library Service

Younghee Noh,Min-Ju Choi,Yong-Wog Choi,Sin-Won Jeong,Eun-Ji Jung,Mi-So Kang,Jin-Young Kim,Kyung-Won Lee,Sung-Jae Lee,Seon-Hye Oh,So-Yeon Park,Sung-Chul Shin,Da-Jeong Suh 건국대학교 지식콘텐츠연구소 2011 International Journal of Knowledge Content Develop Vol.1 No.1

축소모형에 의한 싱크-홀 보강슬래브의 실험적 성능평가

노삼영 ( Noh Sam-young ),권현호 ( Gown Hyeon-ho ),신동춘 ( Sin Dong-chun ),홍찬윤 ( Hong Chan-yun ),유성용 ( Yu Seong-yong ) 한국구조물진단유지관리공학회 2010 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.14 No.1

Sink-hole is a kind of ground settlements caused by collapse of the underground space when the important structure is constructed on the closed mine tunnel. Thus Sink-hole must be reinforced certainly. Therefore, in this study, experimental performance evaluation of Sink-hole-reinforcing slab is done by scaled model. In this time, rock and silt which is selected by soil condition, are used as ground model which scale is same ratio as reinforced slab. This experiment estimate through the stability of reinforced slab and the ground mutual behavior analysis.

The Mechanism of Antibacterial Activity of Tetrandrine Against <i>Staphylococcus aureus</i>

Lee, Young-Seob,Han, Sin-Hee,Lee, Su-Hwan,Kim, Young-Guk,Park, Chung-Berm,Kang, Ok-Hwa,Keum, Joon-Ho,Kim, Sung-Bae,Mun, Su-Hyun,Seo, Yun-Soo,Myung, Noh-Yil,Kwon, Dong-Yeul Mary Ann Liebert 2012 Foodborne pathogens and disease Vol.9 No.8

중증 화상 환자에서 영양지원

박지영,목혜숙,신현선,노순예,김애심,백금선,김도헌,허준,전욱 대한화상학회 2003 대한화상학회지 Vol.6 No.2

전신성 홍반성 낭창과 동반된 시신경염 1 예

한대석,강신욱,김순현,이호영,고원기,서정훈,신석균,노현진,이루다,최규헌 대한내과학회 1998 대한내과학회지 Vol.55 No.5

Systemic lupus erythematosus(SLE) is a disease of unknown etiology in which tissues and cells are damaged by pathogenic autoantibodies and immune complexes. Optic neuritis in SLE is very rare and the prevalence can be estimated to be approximately 1% of the patients of SLE. The main pathogenesis of optic neuritis with SLE is that of a vaso-occlusive disease in small vessels and the histopathologic appearance has varied from demyelination to definite vascular disease with axonal necrosis. The visual outcome of optic neuritis in SLE has often been poor. The treatments of optic neuritis in SLE are intravenous methylprednisolone, immunosuppressive agents and plasmapheresis. The authors experienced a case of lupus nephritis and CNS lupus which was complicated by optic neuritis in 18-year-old female patient who complained of sudden visual disturbance of the both eyes After treatment with plasmapheresis and systemic corticosteroid, her visual deficit was gradually recovered.

증례 : 혈액종양 ; 림프종 환자에서 리툭시맙 치료 후에 발생한 저감마글로불린혈증 1예

노현진 ( Hyun Jin Noh ),공봉한 ( Bong Han Gong ),김영신 ( Young Sin Kim ),정윤화 ( Yun Hwa Jung ),우인숙 ( In Sook Woo ),한치화 ( Chi Wha Han ) 대한내과학회 2014 대한내과학회지 Vol.87 No.3

Rituximab, an anti-CD20 monoclonal antibody, is an effective target agent against the B lymphocytes in B-cell lymphoid malignancies and various lymphoproliferative diseases. Moreover, the toxicity of rituximab is less severe than that of conventional cytotoxic agents, which has promoted the widespread application of rituximab in the treatment of B-cell lymphoma. However, depletion of B lymphocytes by rituximab, which leads to secondary hypogammaglobulinemia, can cause deterioration of humoral immunity. Although immune reconstitution after hematopoietic stem cell transplantation is known to prevent prolonged hypogammaglobulinemia, very few cases of long-standing hypogammaglobulinemia have been reported. We report herein a case of prolonged hypogammaglobulinemia after rituximab-containing chemotherapy and splenectomy in a patient with non-Hodgkin`s lymphoma and discuss the clinical significance and pathogenetic mechanism of this phenomenon with a literature review. (Korean J Med 2014;87:357-362)

Microleakage of Endodontic Temporary Restorative Materials under Dynamic Loading

Jung, Dong-Ho,Noh, Young-Sin,Lee, Hae-Doo,Chang, Hoon-Sang,Ryu, Hyun-Wook,Min, Kyung-San 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.3

본 연구의 목적은 동적하중 하에서 네 종류의 근관치료용 임시충전재의 밀폐효과를 비교하는 것이다. 44개의 건전한 인간 대구치에 표준차된 근관와동을 형성한 후 Caviton, MD-Temp, IRM 및 ZOE를 이용하여 충전하였다. 이 후, 1% 메틸렌블루 용액에 담근 상태에서 반복하중기를 이용하여 I Hz의 속도로 98 N의 하중을 기능교두에 1,000번 가한 다음 시편을 양분해 미세누출을 평가하고 one-way ANOVA (p = 0.05)와 사후 검정으로 Duncan' s multiple range tests로 통계분석 하였다. Caviton군과 MD-Temp군이 IRM군과 ZOE군보다 통계적으로 적은 미세누출을 보였으며 (p < 0.05), 본 실험결과로 볼 때 Caviton과 MD-Temp가 IRM과 ZOE보다 동적하중 하에서 근관와동 밀폐효과가 우수하다고 사료된다. The purpose of this study was to compare the sealing abilities of four endodontic temporary restorative materials using a methylene blue dye penetration test under dynamic loading. Standardized access cavities were prepared in forty-four intact human permanent molar teeth, and the cavities were restored with Caviton, MD-Temp, IRM, or ZOE. After thermocycling, an intermittent load of 98 N at 1 Hz was applied for 1,000 cycles to the long axis of the functional cusp of each of the teeth, which were immersed in a 1% methylene blue solution. The teeth were split in half, and the linear depth of dye penetration was evaluated according to the criteria. The results were analyzed using one-way ANOVA (p = 0.05) and Duncan' s multiple range test. The results demonstrated that Caviton and MD-Temp showed significantly lower microleakage than IRM and ZOE. It was concluded that Caviton and MD-Temp exhibited better sealing ability than IRM and ZOE under dynamic loading.

인체 췌장암세포주(Capan-1)의 증식에 미치는 amiloride의 억제효과

임대관,김신,김유리,노지훈,이지현,김지연,박무인,정근옥,박건영,구자영 고신대학교 의학부 2004 高神大學校 醫學部 論文集 Vol.19 No.1

Background/Aims Cytoplasmic alkalinization induced by activation of the Na+/H+anti porter which is stimulated upon the addition of growth-promoting agents, such as insulin, epidermal growth factor, phorbol ester, plays an essential role in the initiation on cell proliferation. In the present study the effects of amiloride, a specific and reversible inhibitor of Na+/H+antiporter, on the growth of human pancreatic carcinoma cell line, Capan-1 cells was examined and the effects of 5-fluorouracil (5-FU) were also studied. Cell cycle analysis was done to examine the mechanisms for the inhibitory effects of amiloride. Materials/Methods The growth of Capan-1 cells were examined by counting cell number on two and four days treatment with 1 μM, 5 μM, 10 μM, 20 μM, 40 μM, 80 μM, 160 μM amiloride, and 0.1 ㎍/㎖, 0.3 ㎍/㎖ 5-FU, after plating Capan-1 cells into 35-mm2 plastic dishes at d density of 10x104 cells/dish. The reversibility of the effects of amiloride was examined on two day to eight days treatment with 20 μM amiloride after seeding 2×104 cells/dish. Cell cycle analysis was done on the sells after four days treatment with 20 μM amiloride. Results Amiloride significantly inhibited the growth of Capan-1 cells in a dose-dependent fashion (p<0.05). The inhibitary effect of amiloride on the growth of Capan -1 cells was firstly shown at the concentration of 5 μM, which is not so higher than the concentration of 0.1-0.2 μM attainable by administration of usual dose of amiloride (5-10㎎). Forty-eight percent inhibition of growth was found at an amiloride concentration of 20μM after 4 days treatment, and ninety-three percent inhibition of growth was found at an amiloride concentration of 160μM after 4 days treatment. The inhibitory effect of amiloride on growth of Capan-1 cells was reversible since removal of amiloride by a media change after 48 hours treatment lead to significantly more growth than amiloride treated group (p<0.05). The reversibility of growth inhibition suggests that amiloride in not a non-specific cytotoxin for Capan-1 cells. Amiloride combined with 5-FU significantly inhibited the growth of Capan-1 cells in a dose-dependent fashion compared to an amiloride or a 5-FU alone (p<0.05). After four days treatment with 20 μM amiloride, the faction of cells in G0-G1 phase, S phase and G2-M phase was 47.3%, 35.8%, 16.9% respectively in the amiloride group (20 μM), and 44.3%, 37.1%, 18.6% in the control group. showing no significant differences between the two groups. Conclusions Amiloride significantly inhibited the growth of Capan-1 cells in a dose-dependent fashion, which was reversible. The reversibility of growth inhibition suggests that amiloride is not a non-specific cytotoxin for Capan-1 cells. The concentration of 5 μM, which is not so higher than the concentration of 0.1-0.2 μM attainable by administration of usual dose of amiloride (5-10㎎), which suggests amiloride or its analogues may be used alone or in conjunction with 5-FU for the treatment of pancreatic carcinoma. Further study is needed to clarify the effects of more potent analogues of amiloride on the growth of human pancreatic carcinoma cells.

위절제술이 면역 체계 및 내분비계에 미치는 영향:마취 방법 및 술후 제통법에 따른 비교

김명희,최영순,신백효,노재형,김성년,한태영,은종신 대한마취과학회 1998 Korean Journal of Anesthesiology Vol.34 No.5

Background : Authors have undertaken this study to see if the choice of anesthesia can directly or indirectly provide immunomodulation for cytokines, to determine the relationship of cytokines and hypothalamo-pituitary-adrenal axis in stomach cancer surgery patients, and also to see whether the amount of morphine administration and choice of analgesia can influence cytokine release, and possibly immunity Methods : Total 19 gastric cancer surgery patients were randomly assigned in double-blind fashion into two groups. Group-G(n=9) was provided with general anesthesia plus morphine intravenous patient controlled analgesia(IV-PCA), whereas group-GE(n=10) with preemptive epidural and general anesthesia plus continuous epidural analgesia for control of postoperative pain. At predetermined time interval, proinflammatory cytokines and stress hormones were evaluated with visual analog pain scale. Simultaneous assessments of operating and anesthesia time, total morphine doses, the time to recovery of gastrointestinal function and incidences of complications were also made. Results : Demographic data, the durations of operation and anesthesia and recovery of gastrointestinal function were similar in both groups. Total morphine doses were approximately four times greater in group-G. Secretions of interleukin-1 , TNF and epinephrine were blocked by preemptive epidural anesthesia, meanwhile, interleukin-6 as well as ACTH and cortisol were not. After 24 hours after skin incision, the differences of cytokines, ACTH and cortisol between two groups were dissipated. In spite of these hormonal findings, visual analog pain scale could not disclose any differences. Incidences of complications were statistically insignificant except that of itching in group-GE. Conclusion: Preemptive epidural anesthesia and analgesia can partially block only some of cytokines and stress hormones, and these effects do not have clinically relevant long term influences. The amounts and means of morphine administered by continuous epidural analgesia block or IV-PCA demonstrated no evidence of immunosuppression at clinical dose range. (Korean J Anesthesiol 1998; 34: 1036∼1045)

Push-out bond strengths of fiber-reinforced composite posts with various resin cements according to the root level

Chang, Hoon-Sang,Noh, Young-Sin,Lee, Yoon,Min, Kyung-San,Bae, Ji-Myung The Korean Academy of Prosthodonitics 2013 The Journal of Advanced Prosthodontics Vol.5 No.3

PURPOSE. The aim of this study was to determine whether the push-out bond strengths between the radicular dentin and fiber reinforced-composite (FRC) posts with various resin cements decreased or not, according to the coronal, middle or apical level of the root. MATERIALS AND METHODS. FRC posts were cemented with one of five resin cement groups (RelyX Unicem: Uni, Contax with activator & LuxaCore-Dual: LuA, Contax & LuxaCore-Dual: Lu, Panavia F 2.0: PA, Super-Bond C&B: SB) into extracted human mandibular premolars. The roots were sliced into discs at the coronal, middle and apical levels. Push-out bond strength tests were performed with a universal testing machine at a crosshead speed of 0.5 mm/min, and the failure aspect was analyzed. RESULTS. There were no significant differences (P>.05) in the bond strengths of the different resin cements at the coronal level, but there were significant differences in the bond strengths at the middle and apical levels (P<.05). Only the Uni and LuA cements did not show any significant decrease in their bond strengths at all the root levels (P>.05); all other groups had a significant decrease in bond strength at the middle or apical level (P<.05). The failure aspect was dominantly cohesive at the coronal level of all resin cements (P<.05), whereas it was dominantly adhesive at the apical level. CONCLUSION. All resin cement groups showed decreases in bond strengths at the middle or apical level except LuA and Uni.