Facile and fast Na-ion intercalation employing amorphous black TiO_2-x/C composite nanofiber anodes

Lee, Na-Won,Jung, Ji-Won,Lee, Jun-Seo,Jang, Hye-Yeon,Kim, Il-Doo,Ryu, Won-Hee Elsevier 2018 ELECTROCHIMICA ACTA Vol.263 No.-

<P><B>Abstract</B></P> <P>Structural and electronic modification of titanium oxide (TiO<SUB>2</SUB>) nanomaterials induced by the co-introduction of fully disordered glass phase and oxygen vacancies can lead to remarkable advances in the electrode performance in emerging energy storage systems. We report on the effective co-creation of fully amorphous nanofibers (NFs) composed of black TiO<SUB>2-x</SUB> and conductive carbons throughout the NF structure, and evaluate the materials as potential anodes in sodium-ion batteries. The black TiO<SUB>2-x</SUB> nanofiber is successfully fabricated by electrospinning a precursor solution followed by a two-step sequential thermal treatment in an air and reducing atmosphere. The NF electrode could deliver approximately two-fold higher 2nd discharge capacity and an excellent kinetic performance even under high rates compared to that delivered by anatase-structured white TiO<SUB>2</SUB> NFs used as reference, because of (i) an inherent free volume in the glass phase corresponding to the enlarged Na<SUP>+</SUP> sites, (ii) increased electrical conductivity (low bandgap) resulting from the presence of Ti<SUP>3+</SUP>, (iii) introduction of conductive carbon agents around the TiO<SUB>2-x</SUB> domain, and (iv) one-dimensional NF feature allowing numerous Na<SUP>+</SUP> reaction sites at the electrochemical interface. We also elucidate the morphological and structural changes in the nanofibers after discharge and charge by <I>ex-situ</I> characterizations.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We succeed in co-creating amorphous nanofiber structure composed of black TiO<SUB>2-x</SUB> and conductive carbons. </LI> <LI> Black TiO<SUB>2-x</SUB>/carbon nanofibers are prepared by electrospinning followed by a two-step thermal treatment. </LI> <LI> Black TiO<SUB>2-x</SUB>/carbon nanofiber delivers excellent electrochemical performance compared to those of anatase TiO<SUB>2</SUB> nanofiber. </LI> <LI> The benefits and reaction mechanism of the black TiO<SUB>2-x</SUB>/carbon nanofiber anode in the Na-ion cell operation is elucidated. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Cellulose 첨가 식이가 고콜레스테롤 식이를 섭취한 암컷 쥐의 혈중 지질 농도에 미치는 영향

서지나,최미자 啓明大學校 生活科學硏究所 2006 科學論集 Vol.32 No.-

Numerous studies have been done on the effect of fiber on cholesterol metabolism. Most of studies reported a hypocholesterolemic action of fiber in rats fed a high cholesterol diet. However, a few studies reported that addition of cellulose to the diet increased the serum level of cholesterol in rats. Therefore, more studies are needed to figure out the effects of cellulose on cholesterol metabolism. The purpose of this study was to investigate the effect of dietary cellulose supplementation on plasma lipid concentrations in rats fed a high cholesterol diet. Twenty female rats (body weight 190 ± 2.9 g) were randomly divided into two groups. The rats in the control group were fed on 5% cellulose diet (control) and those in the experimental group were fed with 10% cellulose diet. All rats were fed with the experimental diets and deionized water ad libitum for 5 weeks. The plasma lipid concentrations were measured using commercial kits with enzymatic methods. There were no significant differences in the body weight gain, food intake and food efficiency ratio between the control and experimental groups. The rats fed cellulose supplemented diet had significantly higher plasma total cholesterol concentration than those fed control diet. The plasma concentrations of triglyceride were slightly reduced in the rats fed cellulose supplemented diet compared to those fed control diet. But plasma triglyceride concentrations were not significantly different between two groups. More detailed research is necessary to explain why the effectiveness of cellulose in reducing the plasma cholesterol concentration in high cholesterol fed rats has been different.

보리순의 영양성분 조성

서혜지,최용민,김상천,이준수,이기택,정명근,천지연,황진봉,남진식,서우덕,황영,김행란,김세나 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

D-Amphetamine이 니코틴성 흥분작용에 의한 카테콜아민 분비작용에 미치는 영향

임건한,서유석,민선영,임지연,김용직,나광문,임동윤 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

본 연구의 목적은 d-arphetamine이 흰쥐의 적출부신 관류모델에서 니코틴 수용체 흥분에 의한 카테콜아민(CA) 유리작용에 미치는 영향을 검색하여 그 작용기전을 규명하고자 하였다. D-amphetamine은 흰쥐 부신정맥내로 60분간 관류시 d-amphetamine자체는 약한 CA 분비작용을 나타내었으나, d-amphetamine (30 μM)을 비롯한 강력한 neuronal nicotine 수용체 작용제인 cytisine (50 μM) 및 epibatidine (30 μM)에 의한 CA 유리작용을 처음 4-10분 동안만 유의하게 증강시켰다. 또한, d-amphetamine (30 μM)은 60분간 부신정맥 내로 관류한 상태에서 dihydropyridine L-형 칼슘통로 개방약물인 Bay-K-8644 (10 μM)과 세포질내 칼슘저장고에서 Ca^(2+) ATPase 억제제인 cyclopiazonic acid (10 μM)의 CA 유리작용을 처음 4분간만 유의하게 증강시켰다. 그러나, 고농도의 d-amphetamine (500 μM)은 상기한 모든 분비촉진제의 CA분비작용을 오히려 억제하였다. 이와 같은 연구결과로 보면, 흰쥐 관류 부신수질에서 d-amphetamine은 낮은 농도에서는 콜린성 니코틴 수용체 흥분에 의한 카테콜아민 분비반응을 증강시키지만, 고농도에서는 오히려 억제적으로 작용함을 시사한다. 따라서, d-amphetamine은 용량에 따라서 흰쥐 적출 관류부신수질의 니코틴 수용체의 작용제 및 길항제로 이중 작용(dual action)을 나타내는 것으로 생각된다. 이러한 d-amphetamine의 작용은 흰쥐 부신수질 크롬친화세포의 dihydropyridine계 L-형 칼슘통로의 활성화 및 세포 내 칼슘저장고로부터 칼슘유리작용과 관련성이 있는 것으로 사료된다. The purpose of the present study was to examine the effect of d-amphetamine on CA release evoked by nocotinic receptor stimulation from the isolated perfused model of the rat adrenal gland, and to establish its mechanism of action. D-amphetamine(30 μM), when perfused into an adrenal vein of the rat adrenal gland for 60 min, enhanced the CA secretory responses evoked by ACh (5.32 mM), nicotine (30 μM), cytisine (50 μM, a selective neuronal nicotinic Nn-receptor agonist) and epibatidine (30 nM, a selective neuronal nicotinic Nn receptor agonist) only for the first period (4~10 min), although it alone has weak effect on CA secretion. Moreover, d-amphetamine (30 μM) in to an adrenal vein for 60 min also augmented the CA release evoked by BAY-K-8644, an activator of the dihydropyridine L-type Ca^(2+) channels, and cyclopiazonic acid, an inhibitor of cytoplasmic Ca^(2+) ATPase only for the first peroid (4 min). However, in the presence rather inhibited the CA secretory responses evoked by the above all of secretagogues. Taken together, these experimental results suggest that d-amphetamine at a low concentration enhances the CA secretion from the rat adrenal medulla evoked by stimulation of cholinergic nicotininc receptors, but at a high concentration it rather inhibits them. It semms that d-amphetamine has dual action acting as both agonist and antagonist at nicotinic receptors of the isolated perfused rat adrenal medulla, which are might be dependent on the concentration. It is also thought that these actions of d-amphetamine are probably relevant to the activation of the dihydropyridine L-type Ca^(2+) channels located on the rat adrenomedullary chromaffin cell membrane and release of Ca^(2+) from the cytoplasmic store.

病院 外來 患者에 있어서의 Toxoplasma 抗體價 分布에 關한 調査 硏究

辛大煥,徐志澤,李英河,羅榮彦 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

The results of Sabin & Feldman dye test for the detection of Toxoplasma antibody titer among 454 hospital outpatients were summarized as follows: 1. Among 454 test sera, 101 cases were positive, the positive rate was 22.2%. 2. According to age group, dye test positive rates were 33.3% (0-9 age group in years), 32.8% (40-49 age group in years), 31.6%(over 60 age group in years), 28.6%(10-19 age group in years), 20.1%(20-29 age group in years), 20.0%(30-39 age group in years), and 18.3%(50-59 age group in years). 3. According medical field, dye test postive rates were high in neurology(40%), pedatrics(37.5%), dermatology (36.4%), and surgery(30.6%) 4. Among 194 obstric and gynecological patients, abortion, anomaly, and retroversioflexion had high Toxoplasma antibody titers, but inflammatory disease, cancer, pregnancy and infertility revealed as relatively same antibody titers.

Metastatic papillary thyroid cancers with malignant pleural effusion aggravated during thyroid hormone withdrawal for radioiodine therapy

Seo, Ji Hye,Je, Ji Hye,Lee, Hyun Jung,Na, Young Ju,Jeong, Il Woo,An, Jee Hyun,Kim, Sin Gon,Choi, Dong Seop,Kim, Nam Hoon Yeungnam University College of Medicine 2015 Yeungnam University Journal of Medicine Vol.32 No.2

L-thyroxine (LT4) withdrawal prior to radioactive iodine (RAI) ablation therapy is a commonly used method for successful treatment of patients with papillary thyroid cancer (PTC). However, a prolonged period of hypothyroidism induced by LT4 withdrawal is sometimes associated with impaired quality of life and cardiopulmonary dysfunction in PTC patients. Furthermore, LT4 withdrawal may have a trophic effect on residual cancer by means of increased thyrotropin. We report on 2 cases of metastatic PTC patients with malignant pleural effusion (MPE) whose disease showed rapid worsening after LT4 withdrawal and RAI therapy. The first case is a 65-year-old woman who had PTC with multiple distant metastases and MPE. During LT4 withdrawal for RAI therapy, MPE showed rapid worsening, and the patient required repetitive therapeutic thoracentesis. The second case is a 49-year-old woman with PTC who underwent 3 additional operations for cancer recurrence in the neck lymph nodes and 6 times of RAI treatments. While preparing for the $7^{th}$ RAI treatment by withdrawing LT4, she developed MPE which became progressively aggravated after RAI therapy. Both patients experienced increased pleural effusion during the LT4 withdrawal period and a rise in the thyroglobulin level was observed after RAI therapy. MPE was not controlled with therapeutic thoracentesis and pleurodesis. Eventually, both patients died of rapid disease progression after RAI therapy. In summary, LT4 withdrawal may have an adverse effect on metastatic PTC patients, particularly those with MPE.

Poster Session : PS 1297 ; Endocrinology : Cases of Differentiated Thyroid Carcinoma Which Ended Up Poor Prognosis after Radioidoine Ablation Treatment

( Ji Hye Seo ),( Nam Hoon Kim ),( Dong Seop Choi ),( Sin Gon Kim ),( Hee Young Kim ),( Jee Hyun An ),( Sun Hwa Kim ),( Kyeong Jin Kim ),( Ji Hye Je ),( Young Ju Na ),( Hyun Jung Lee ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: L-thyroxine (LT4) withdrawal is a commonly used method prior to radioactive iodine (RAI) ablation treatment in differentiated thyroid cancer (DTC) patients. However, a prolonged period of hypothyroidism may reduce quality of life in DTC patients. Furthermore, LT4 withdrawal may have trophic effect on residual cancer by increased TSH and deteriorate cardiac function. We reported two cases of high-risk DTC patients with malignant pleural effusion who underwent rapidly worsening of the disease after LT4 withdrawal and RAI therapy. Patient findings: The first case involved a 65-year-old women who had papillary thyroid cancer with multiple distant metastases and malignant pleural effusion. During LT4 withdrawal for the RAI therapy, rapid worsening malignant pleural effusion required repetitive therapeutic thoracentesis. The second case involved a 49-yearold woman who had papillary thyroid cancer and had undergone three additional operations for neck lymph node cancer recurrences and four RAI treatments. During planning the 5th RAI therapy with LT4 withdrawal, malignant pleural effusion was developed, and it was progressively aggravated after RAI treatment. Both of two cases were high-risk patients accompanied with extra-thyroidal invasion and LN metastasis at the time of the diagnosis. Both experienced increased pleural effusion during the LT4 withdrawal period and a rise in the thyroglobulin level after RAI therapy. Malignant pleural effusion was not controlled with therapeutic thoracentesis and pleurodesis. Eventually, both of them came to death due to rapid disease progression after RAI treatment. Conclusion: LT4 withdrawal for RAI treatment may be harmful in high-risk DTC patients, especially with distant metastases and malignant pleural effusion.

CASE REPORT : Metastatic papillary thyroid cancers with malignant pleural effusion aggravated during thyroid hormone withdrawal for radioiodine therapy

( Ji Hye Seo ),( Ji Hye Je ),( Hyun Jung Lee ),( Young Ju Na ),( Il Woo Jeong ),( Jee Hyun An ),( Sin Gon Kim ),( Dong Seop Choi ),( Nam Hoon Kim ) 영남대학교 의과대학 2015 Yeungnam University Journal of Medicine Vol.32 No.2

L-thyroxine (LT4) withdrawal prior to radioactive iodine (RAI) ablation therapy is a commonly used method for successful treatment of patients with papillary thyroid cancer (PTC). However, a prolonged period of hypothyroidism induced by LT4 withdrawal is sometimes associated with impaired quality of life and cardiopulmonary dysfunction in PTC patients. Furthermore, LT4 withdrawal may have a trophic effect on residual cancer by means of increased thyrotropin. We report on 2 cases of metastatic PTC patients with malignant pleural effusion (MPE) whose disease showed rapid worsening after LT4 withdrawal and RAI therapy. The first case is a 65-year-old woman who had PTC with multiple distant metastases and MPE. During LT4 withdrawal for RAI therapy, MPE showed rapid worsening, and the patient required repetitive therapeutic thoracentesis. The second case is a 49-year-old woman with PTC who underwent 3 additional operations for cancer recurrence in the neck lymph nodes and 6 times of RAI treatments. While preparing for the 7th RAI treatment by withdrawing LT4, she developed MPE which became progressively aggravated after RAI therapy. Both patients experienced increased pleural effusion during the LT4 withdrawal period and a rise in the thyroglobulin level was observed after RAI therapy. MPE was not controlled with therapeutic thoracentesis and pleurodesis. Eventually, both patients died of rapid disease progression after RAI therapy. In summary, LT4 withdrawal may have an adverse effect on metastatic PTC patients, particularly those with MPE.

Secondary metabolites from the stem of Viburnum erosum

Seo-ji In,Kyeong-Hwa Seo,Na-Young Song,Ji-Hae Park,Nam-In Baek,차병주,Eun-Mi Ahn 한국약용작물학회 2013 한국약용작물학술대회 발표집 Vol.2013 No.05

The study on sleep quality, internet addiction, and academic achievement in nursing students

Na Yoon Kim,Na Yeon Kim,Jin ah Kim,Ji won Kim,Chan Seul Park,Jae Eun Lee,Ji Su Lee,Seo Hee Jung,Sungwon Park 한국간호과학회 2019 한국간호과학회 학술대회 Vol.2019 No.10