방광의 염증성 가종양 1례

정영봉,배준,권명훈,김상익,김경수 大韓泌尿器科學會 2001 Korean Journal of Urology Vol.42 No.3

Interleukin-2와 결핵균 30 kDa 항원이 구개편도 및 말초혈액 T 세포 증식에 미치는 상승효과

박정규,박찬권,조은경,김화중,백태현,고필준,김병국,남부현,나기상,박찬일 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.1

Widespread use of BCG has not controlled tuberculosis, and more effective vaccines are clearly needed. Although chemotherapy will remain the mainstay of antituberculosis treatment, the use of adjunctive immunotherapeutic modalitites is attractive, particularly in persons with drug-resistant tuberculosis. Administration of IL-2 or IFN-γto tuberculosis patients enhance bacillary elimination. Cell-mediated immunity is the critical protective immune response in tuberculosis. Mycobacterial antigens are recognized by T cells and that elicit production of protective cytokines are potentially important vaccine antigens. The 30 kDa antigen is secreted in large quantities by growing mycobacteria. That antigen elicits greater proliferation in lymphocytes from healthy tuberculin reactors than healthy tuberculin nonreactors. In this study, the T lymphocyte proliferative responses to 30 kDa antigen from Mycobactrium tuberculosis H37Rv were examined by using tonsilar and peripheral blood lymphocytes from PPD(+) and PPD(-) tonsilectomized persons. When cultured with 30 kD antigen, tonsilar mononuclear leukocytes and T cells of PPD(+) demonstrated more ^3H-thymidine incorporation than PPD(-) persons (stimulation index was 2.5 and 1.9, 0.8 and 1.0, repectively). Peripheral blood mononuclear cells (PBMC) and peripheral blood T lymphocytes were shown the similar responses to this antigen. The combination of IL-2 and 30 kDa antigen elicited a significant proliferative responsiveness in tonsilar mononuclear leukocytes and T cells of PPD(+) persons (SI was 20 and 14.1). PBMC and peripheral blood T cells of PPD(+) persons were also shown a significant responsiveness, but PPD(-) persons did not show. These results demonstrate that the 30 kDa antigen and IL-2 have a synergistic stimulatory property in mycobacteria sensitizing lymphocytes.

전자선치료시 유효 선원 피부간 거리 결정에 관한 연구

이병구,이상록,정덕양,권영호,김유현 高麗大學校 倂設 保健大學 保健科學硏究所 2002 保健科學論集 Vol.28 No.2

Under the various clinical circumstances, there is a condition to change source to skin distance(SSD). It is possible to correct photon beam by well-known inverse square law. On the other hand, the electron beam is not exact location of source, that's why it is difficult to apply as it is. In case of electron beam, we should correct the difference of SSD by measure effective SSD . There are many ways to measure effective SSD. In this study, Faiz Khan's method was used. The measurement energy is 6,9,12,16,20 MeV and field size is set standard applicator 6×6, 10×10, 15×15, 20×20, 25x25㎠. From the bottom of the standard applicator to skin distance is set to 5㎝. So we measured dose at the gap to 0∼20㎝. According to a production company of linear accelerator, or even though same production company, the qualities of electron beam can be different. So, effective SSD can be different every several accelerator. Therefore, it is desirable to use the effective SSD measured at every electron beam energy and field size actually.

Management of Traumatic Cervical Spondyloptosis with an Unsealable Dura Tear: A Case Report

Jeong Woo Kwun,Sang Yoon Kim,Sang Koo Lee,Young-Jin Kim 대한신경손상학회 2021 Korean Journal of Neurotrauma Vol.17 No.2

Cervical spondyloptosis is defined as dislocation of the spinal column, most often caused by trauma. Due to transection of the spinal cord, severe neurological deficits are common. Here, we reviewed the case of a young man who presented with mental stupor and complete tetraplegia below the level of C5. The patient's left shoulder was sucked into a machine and subjected to strong lateral bending and distraction. Computed tomography (CT) scan and magnetic resonance imaging revealed fracture dislocation and complete transection of the spinal cord at the C5–6 level. Three-dimensional CT scan showed coronal and sagittal spondyloptosis. He underwent open reduction with two surgeries performed via the anterior and posterior approaches: C5–6 anterior cervical discectomy and fusion and lateral mass screw fixation with allograft from C3 to C7. In addition, both ends of the huge dura defect were sutured. We report the clinical history, imaging findings, and surgical management of spondyloptosis with a complete transected spinal cord containing a considerable dura tear.

Development of an Automatic Silkworm Breeding System

Sang Kwun Jeong,장성욱,Jin kook Son,Seong-Wan Kim 한국잠사학회 2023 International Journal of Industrial Entomology Vol.47 No.2

This paper is about the development results of an automatic silkworm breeding system to reduce labor and time by automatically performing the works for silkworm droppings changing and feed its food. It consists of an automatic guided vehicle and a processing unit. The automatic guided vehicle transports a silkworm dropping changing frame mounted on a silkworm tray stand, and the processing unit takes over the dropping changing frame on it, removes excrement contained the droppings changing frame and feeds silkworm food. In the case of the current silkworm farming, because the breeding period for large silkworms (4 to 5 stage) is short to 14 days and the supply of mulberry leaves takes 98% of the total amount of mulberry leaves needed for breeding silkworms at this time, labor concentration is intensive, and all breeding works depends on manpower. Therefore, it was difficult to breed large silkworms on a large scale. Moreover, silkworms are bred by adding Silkworm bed (Seop) and mulberry in the silkworm tray, and their droppings changing is to separate silkworms and excrement by moving silkworm trays one by one, and the production cost increases due to the high-cost manpower for silkworm breeding. To solve this problem, technology for automating silkworm breeding has also been developed. However, there is still a limitation that silkworm feeding and droppings changing works are not suitable for mass breeding because a lot of labor and time are spent depending on manual work. Therefore, a new silkworm breeding system for breeding silkworm automatically is needed and so we developed an Automatic Silkworm Breeding System applying the droppings change frame, the inverting unit, the feeding silkworm food device and automatic guided vehicle.

피판하 혈종이 Flap Survival에 미치는 영향에 대한 실험적 연구

정성훈,김석권,김성수,정용휘 大韓成形外科學會 1984 Archives of Plastic Surgery Vol.11 No.4

In flap surgery used frequently in the scope of plastic surgery, surgeons sometimes have been experienced the flap necrosis, which is caused by poor vascular supply due to inadequate design of flap, gravity, twisting or kinking of flap, pressure, infection and underlying hematoma, and so on, it leads to undesirable postoperative result. Among them, hematoma--related flap necrosis is the most unpredictable and frequent, thus it is very urgent to grope its cause and the way to overcome this complication. But precise mechanism of flap necrosis has not been revealed yet, the mechanism of hematoma related flap necrosis which is explained until now are; increased internal pressure, constituent of homolysate. But the way to overcome hematomarelated flap necrosis is hardly reported. Though they say early surgical removal of hematoma will prevent most of flap necrosis, the previous studies have not reported the other nonsurgical method and the adequate time of removal of hematoma. So the purpose of this study is to describe; What is the mechanism of flap necrosis due to underlying hematoma. What method of removal of hematoma will increase the flap survival. When the hematoma should be removed to increase the flap survival. The results of the experiment are follows; 1) Flap necrosis was severe significantly in blood, blood clot and hemoglobin injected group. 2) Flap necrosis due to underlying hematoma is thought to be caused by the toxic effect of red blood cell or hamolysate of red blood cell. 3) Surgical removal group of the underlying hemotoma had a significant better result in survival of flap than no removal control, hydrogen peroxide irrigation and urokinase injected group. 4) Surgical removal of the underlying hematoma carried out within 6 hours after injection of blood beneath the flap made no statistically significant difference in flap survival as compared with no blood control group. Surgical removal of hematoma 6 hours after blood injection or other nonsurgical methods of revealed in rather better result in flap survival as compared with no removal control group, but there was a statistically significant difference in survival compared with no blood control group.

설피판을 이용한 구개열공의 치험

정성훈,서창덕,김석권,김성수 大韓成形外科學會 1986 Archives of Plastic Surgery Vol.13 No.1

Palatal fistula may occur after palatoplasty, although its incidence was markedly decreased with the advent of operative technique, it may caused by inadequate approximation, necrosis of the flap, tension, trauma. etc., and produce many problems including the speech disturbance and embarassing escape into the nose of fluid and food. Most of the palatal fistulas develop along the suture line in a small size, so they can be corrected easily by palatoplasty or various flap surgery using the local mucoperiosteum. But it is very difficult to repair if the fistula is very large or located anterior to the hard palate. Buccal mucosal or vestibular mucosal flaps may settle the problems but there are many limitations on the size and location. And other extraoral distant flaps need not only many surgical steps but also cause inconvinience. But tongue flap profides an excellent method for the repair of large anterior palatal fistula because of high mobility and rich blood supply and low donor site morbidity. We treated the two cases of large palatal fistulas using the distally based dorsal tongue flap and report with a review of articles.

부산 지역의 응급환자 이송체계에 대한 전향적 분석

정진우,조석주,이형렬,김성권,정준영 대한응급의학회 2002 대한응급의학회지 Vol.13 No.1

Purpose: Overcrowding of emergency departments remains an unsolved international issue and has led to not a few unfavorable consequences. For a solution of this, appropriate patient triage and selection of appropriate hospitals to which to be transported will be essential. Methods: The authors performed a prospective analysis of 690 patients transported via emergency transport services to the Emergency Department of Pusan National University Hospital between May 1,2000 and June 30,2000. Results: Five hundred five cases (73.2%) were considered as appropriate transport, but 185 (26.8%) were not. In 300 cases (43.5%), the hospitals to which the patients were transported had been decided by the patient's family members, in 283 cases (41.0%) by medical professionals, in 70 cases (10.1%) by EMS personnels, and in 37 cases (5.4%) by the patients themselves. In the selection of the hospital to be transported to, patients and family members took the patient's medical condition into consideration less seriously than the other groups, but they had the greatest influence on the decision. Conclusion: The patients and their family members turned out to be unsuitable for the selection of the hospital to be transported to, but they actually had the greatest influence on the selection. The EMS personnels had limited influence on the selection, and they were lacking in ability to select appropriate hospital with the consideration of the patient's condition. For now there's no active regional ambulance destination policy or decision scheme. For the optimization of emergency transport activity, every effort should be made to enhance the role and ability of EMS personnels in patient triage and selection of transported hospital and to develope well-functioning ambulance destination policies as soon as possible.

Sensitivity of MM5 and WRF mesoscale model predictions of surface winds in a typhoon to planetary boundary layer parameterizations

Kwun, Ji Hye,Kim, You-Keun,Seo, Jang-Won,Jeong, Ju Hee,You, Sung Hyup Springer-Verlag 2009 Natural hazards Vol.51 No.1

안면신경 하악분지 손상에 의한 편측 하구순 마비의 교정

정성훈,유성종,김석권,김성수 大韓成形外科學會 1986 Archives of Plastic Surgery Vol.13 No.1

Expressing a smile is one of the most natural and important of human emotions, but the slight asymmetry or weakness about the lip may impose a severe psychologic burden and restrict the personal relations and social life. Damage to the mandibular branch of facial nerve may be encountered following direct injury or parotid surgery, radial neck dissection, rhytidectomy and tumor of the surrounding muscles, Bell's palsy, etc, and result in a drooping of corner of mounth and pull up, flattening and inward rotation of lower lip when a patient smiles. Although there are considerable literatures on the treatment of facial paralysis, there is little specific information of the management of paralysis of the marginal mandibular branch. Section of mandibular branch of opposite facial nerve or myotomy of ipsilateral elevator group may achieve some increase in lip symmetry but they produce unpleasent results such as mask like appearance and difficulty in pronouncing labial consonants. The plication of orbicularis oris muscle or the wedge resection do not provide a natural appearance during smile becuse they use the paralysed muscle. But the transfer of anterior belly of digastric muscle can provide not only acceptable balance at rest, but also a relative degree of symmetry upon smiling and opening the mouth. In addition, operative technique is simple. So the transfer of anterior belly of digastric muscle is excellent method of treatment for the unilateral paralysis of lower lip. We treated two cases of unilateral pralysis of lower lip by transfer of anterior belly of digastric muscle and obtained a satisfactory results. We report them with review of articles.