두경부 암환자의 항암화학요법에 따른 삶의 질 변화

신혜숙,박혜자,박명희,연기순,김훈교,문한림,송혜향 가톨릭대학교 가톨릭대학교 간호대학 호스피스 교육연구소 1999 호스피스논집 Vol.4 No.-

The purpose of this study was to assess the changes in quality of life wish elapse of chemotherapy in head and neck cancer patients. This study was a longitudinal descriptive design. The subjects were 9 patients who had stage III and stage IV head and neck cancer and received neoadjuvant cisplatin and 5-fluorouracil chemotherapy. Linear Analogue Self Assessment Scale (LASA) of the QOL which it includes eleven items(seven physical items appetite, nausea/vomiting, physical well-being, vigor activity, energy, sleepiness, fatigue and four mental items anger, anxiety, depression & vital power) were used to assess the quality of life eleven times(once in the prechemotherapy period and from the 1st day to 10th day postchemotherapy). The means of scores at each time were analyzed by repealed measures of ANOVA and Bonferroni multiple comparison method. The results are as follows : 1. The degree of appetites decreased significantly on the period between third and sixth day compared with that of appetites on the prechemotherapy day (p<0.001). 2. The degree of physical well-being decreased significantly on the period between first and fifth day compared with that of physical well-being on the prechemotherapy day (p<0.001). 3. The degree of nausea/vomiting decreased significantly on the period between first and fourth day compared with that of appetites on the prechemotherapy day (p<0.001). 4. The degree of anger decreased significantly on the second, fourth, eighth and ninth day after chemotherapy compared with that of anger on the prechemotherapy day(p<0.001). 5. The degree of fatigue decreased significantly on the fourth day compared with that of fatigue on the prechemotherapy day(p<0.001). 6. The increment of nausea/vomiting and poor appetite started on the 2.89th day and 3.67th day after chemotherapy, respectively. 7. The increment of sleepiness started on the 2.56th day after chemotherapy. 8. The increment of depression and anxiety started on the 2.33th day and 3.33th day after chemotherapy, respectively. 9. The lowest degrees of nausea/vomiting and poor appetite were 37.00±17.9 % and 28.64±14.94 % after chemotherapy compared with those of nausea/vomiting and poor appetite on the prechemotherapy day, respectively. 10. The lowest degrees of anger and vigor activity were 48.12±28.3 % and 39.83±24.9 % after chemotherapy compared with those of anger and vigor activity on the prechemotherapy day, respectively. 11. The recovery rates of eight items of quality of life (appetite, vigor activity, energy, fatigue, anger, anxiety, depression & vital power) were shown to reach a peak on the tenth day after chemotherapy and be reached to almost 84 % compared with those of quality of life on the prechemotherapy day. 12. The recovery rates of physical well-being and sleepiness were shown to reach to 67.75 % and 95.68 % on the 10th day after chemotherapy compared with those of physical well-belong and sleepiness on the prechemotherapy day. 13. The recovery rates of seven physical items were faster than those of four mental items on the 10th day after chemotherapy. In conclusion, it is suggested that nursing care strategies to improve the quality of life in patients with chemotherapy would be established both physically and mentally, and be extended at least ten days when patients stayed their home after chemotherapy.

Cloning , Regulation and Expression of D - xylose Isomerase Genes

( Myung Kyo Shin ) 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1992 한국미생물생명공학회 학술발표초록집 Vol.1992 No.2

Somatostatin Analogue(Octreotide)치료가 유효했던 췌장성 복수 1예

신정현,김명환,정성희,이성구,서동완,민영일,김선영,유교상,박은택,임병철,나비석,표승일 대한소화기학회 2000 대한소화기학회지 Vol.35 No.4

Pancreatic ascites has the characteristics of highly proteinaceous, amylase-rich intraperitoneal fluid. It usually occurs as a result of rupture of a pseudocyst or disruption of main pancreatic duct during the course of acute or chronic pancreatitis. It can be managed by traditional conservative methods including fasting, total parenteral nutrition and ascites tapping or surgical interventions. Recently, several cases of treating pancreatic ascites with somatostatin analogue (octreotide) successfully have been reported. We experienced a patient with chronic pancreatitis and pancreatic ascites, who was successfully treated by somatostatin analogue (octreotide).

Analysis of an Electromagnetic Actuator for Circuit Breakers

Shin, Dong-Kyu,Choi, Myung-Jun,Kwon, Jung-Lok,Jung, Hyun-Kyo The Korean Institute of Electrical Engineers 2007 Journal of Electrical Engineering & Technology Vol.2 No.3

In this paper, we present an analysis of dynamic characteristics of an electromagnetic actuator for circuit breakers. It is indispensable to simultaneously analyze magnetic, electric, and mechanical phenomena to obtain the dynamic characteristics of the electromagnetic actuator because these phenomena are closely related to each other in an electromagnetic actuator system. The magnetic equations are computed by using the finite element method (FEM). The electric equations and the mechanical equations, which include the time derivative terms, are calculated by using the time difference method (TDM). The calculated results, which have been obtained by means of the FEM and the TDM, are presented with experimental data.

Improving simulated wind fields for a better prediction of radioactive pollutant dispersion

Kyo-Sun Lim,Jong-Myung Lim,Hyeyum Shin,Jingyu Hong,Jiwoo Lee 한국기상학회 2018 한국기상학회 학술대회 논문집 Vol.2018 No.10

The Performance Improvement of a Linear CCD Sensor Using an Automatic Threshold Control Algorithm for Displacement Measurement

Myung-Kwan Shin,Kyo-Soon Choi,Kyi-Hwan Park 제어로봇시스템학회 2005 제어로봇시스템학회 국제학술대회 논문집 Vol.2005 No.6

원료삼의 증삼 및 건조 조건별 홍삼의 품질 및 기능성

김교연(Kyo-Youn Kim),신진기(Jin-Ki Shin),이수원(Su-Won Lee),윤성란(Sung-Ran Yoon),정헌식(Hun-Sik Chung),정용진(Yong-Jin Jeong),최명숙(Myung-Sook Choi),이치무(Chi-Moo Lee),문광덕(Kwang-Deog Moon),권중호(Joong-Ho Kwon) 한국식품과학회 2007 한국식품과학회지 Vol.39 No.5

경북 풍기산 원료삼의 증자 및 건조 조건별 홍삼의 품질 및 기능성을 알아보기 위해 5년 근을 대상으로 증자 조건(2.5, 3.5, 4.5시간)과 건조 조건(열풍건조: 60-65oC/24시간, 40oC/3-4일, 동결 건조: ?80oC/56시간, 원적외선건조: 900 W/62oC/68시간) 별로 이화학적 특성과 ginsenoside 함량을 비교 분석하였다. 시료의 황색도와 갈변도는 지근이 본근에 비해 높은 수치를 보였으며, 증자시간 3.5, 4.5, 2.5시간의 순으로 그리고, 원적외선건조, 열풍건조, 동결건조의 순으로 높은 수치를 보였다. 증자 및 건조시료의 가용성 고형분, 총 페놀, 총 플라보노이드, 산성다당체, 전자공여능등의 특성은 3.5시간 증자와 원적외선 건조가 가장 양호한 결과를 보였다. 조사포닌 함량은 증자시간 및 건조방법에 영향을 받지 않았다. 함량이 높은 ginsenoside-Rg₁, -Re, -Rf, -Rb₂ 등은 증자시간이 길어질수록 감소하였으나 -Rg₃ 및 -Rh₂의 함량은 유의적으로 증가하여 본근은 3.5시간, 지근은 4.5시간 증자시료에서 가장 높은 함량을 보였다(p < 0.01). 증자 시료의 건조방법을 ginsenoside 관점에서 고려한다면 동결건조방법(2,824 mg%)이 열풍건조(2,669 mg%)나 원적외선건조(2,667 mg%)에 비해 가장 타당한 것으로 판단되며, ginsenoside-Rg₃ 및 Rh2의 함량은 동결건조와 열풍건조 간에 유의적인 차이가 없었다. The quality and functional properties of red ginseng in relation to steaming and drying conditions were evaluated. Fresh ginseng (5-year roots), cultivated in the Punggi region, were steamed for 2.5, 3.5, or 4.5 hr, and then dried by hot-air (60-65oC/24 hr and 40oC/3-4 d), freezing (?80oC/56 hr), and infrared (900 W/62oC/68 hr). Hunter’s yellowness (b-value) and browning indexes (420 nm) of the samples were higher in the rootlets than in the main roots. Furthermore, these same index values were found to be high in the order of 3.5, 4.5, and 2.5 hr and infrared, hot-air, and freezing for steaming and subsequent drying, respectively. Analysis of soluble solids, total phenolics, total flavonoids, acidic polysaccharides, and electron donating abilities of the steamed and dried samples showed that 3.5 hr of steaming with infrared drying was optimal. However, crude saponin contents were not influenced by steaming and drying conditions. The contents of ginsenoside-Rg1, - Re, -Rf, and -Rb2, which were the major components in the samples, were reduced with steaming time, while the amounts of -Rg3 and -Rh2 increased, reaching the highest levels at 3.5 and 4.5 hr in the main roots and rootlets, respectively. The contents of -Rg3 and -Rh2 were similar in both the freeze-dried and hot-air dried samples.

Impact of boundary layer simulation on predicting radioactive pollutant dispersion: A case study for HANARO research reactor using the WRF-MMIF-CALPUFF modeling system

Lim, Kyo-Sun Sunny,Lim, Jong-Myung,Lee, Jiwoo,Shin, Hyeyum Hailey Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.1

Wind plays an important role in cases of unexpected radioactive pollutant dispersion, deciding distribution and concentration of the leaked substance. The accurate prediction of wind has been challenging in numerical weather prediction models, especially near the surface because of the complex interaction between turbulent flow and topographic effect. In this study, we investigated the characteristics of atmospheric dispersion of radioactive material (i.e. ¹³⁷Cs) according to the simulated boundary layer around the HANARO research nuclear reactor in Korea using the Weather Research and Forecasting (WRF)-Mesoscale Model Interface (MMIF)-California Puff (CALPUFF) model system. We examined the impacts of orographic drag on wind field, stability calculation methods, and planetary boundary layer parameterizations on the dispersion of radioactive material under a radioactive leaking scenario. We found that inclusion of the orographic drag effect in the WRF model improved the wind prediction most significantly over the complex terrain area, leading the model system to estimate the radioactive concentration near the reactor more conservatively. We also emphasized the importance of the stability calculation method and employing the skillful boundary layer parameterization to ensure more accurate low atmospheric conditions, in order to simulate more feasible spatial distribution of the radioactive dispersion in leaking scenarios.

동해안 산불피해지 복구를 위한 산림생산력의 추정

구교상 ( Kyo Sang Koo ),이명종 ( Myung Jong Lee ),신만용 ( Man Yong Shin ) 한국농림기상학회 2010 한국농림기상학회지 Vol.12 No.1

In order to rehabilitate forest sites damaged by wildfire via natural or artificial restoration, it is important to determine right tree species, which can acclimate to biogeoclimatic environment at the sites. The objectives of this study were to develop site index equation of different tree species for estimating forest productivity and to provide information on species selection for post-wildfire restoration. Site index equation was developed based on environmental information from wildfire damaged areas in Gangneung, Goseong, Donghae, and Samcheok, where were located in east coastal areas of South Korea. Despite the small numbers (4~5) of environmental variables used for the development of the site index equations, statistical analysis (e.g. mean difference, standard deviation of difference, and standard error of difference) showed relatively low bias and variation, suggesting that those equations can provide relatively high capability of estimation and practical applicability with high effectiveness. The small numbers of the variables enabled the model to be applied in a wide range of usages including determination of appropriate tree species for post-wildfire restoration. The estimation of forest site productivity showed the possibility of large distribution in east coastal region as the best site for Korean ash (Fraxinus rhynchophylla) and original oak (Quercus variabilis) that can be used for firebreak in the region. These results imply that damages by forest fire can be reduced significantly by replacing existing pure coniferous forests in the area with ones dominated by broadleaved deciduous stands, which can play an important role as fire break and/or prevent a transition from surface fire to crown fire.

MMA 알고리즘을 이용한 Decision Feedback Equalizer ASIC 칩 설계

신대교(Shin Dae Kyo),선우명훈(Myung Hoon Sunwoo) 한국통신학회 2000 한국통신학회 학술대회 및 강연회 Vol.2000 No.5