市販 澱粉水解酵素의 活性度 比較

金春子,裵仁淑,梁濟在,李明子,李順子 梨花女子大學校 藥學硏究所 1961 梨花藥學硏究 Vol.- No.2

Purge & Trap-GC를 이용한 의약품 필름코팅 정제 중 잔류용제에 관한 연구

장준식,이명자,소유섭,문춘선,이주헌,박희라,김진숙,강경모,이선옥,방성연,유미자,유문균,금오성,이병욱 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

의약품은 약물을 생체에 적풋하기 위하여 유효성분의 효과가 언제나 일정하게 확보되고 사응에 편리하도록 만들어지는 것이므로 유효썽분 이외에 약효에 영향을 주지 않는 성분이 첨가되는 경운가 많다. 이 때 사용되는 용매들은 제피의 광택 및 건쪼시간의 단축 등을 위하여 휘발점이 낮을 용매들이 주로 사용되어진다. 본 연구는 의약품 필름코팅정제 중 잔류용매 4종(chlorofonr benzen, trichloro ethylen, 1,4-dioxane)에 대한 변형된 pirge & trap-GC 장치를 이용한 동시분석방법을 개발하였으며, 각 표준품의 RSD 값은 chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69% and 1,4-dioxane 3.41%였다. 또한 시중 유통중인 의약품 50종에 대하여 잔류웅매 양을 측정하였으며, 검출되는 잔류용매는 한 건도 없었다. This study nras carried out to develope the analytical method for the mixture of chlorefonn, benzen, trichloroethylen and 1,4-dioxane simultaneously and determine the remainingorgauic solvents in coating tablets by Purge & Trap-GC. The results were as follouFs ; 1. Chloroform, benzen, trio:tloroethylen and 1,4-dioxane separated by tenax #5 trap by HP-624GC column by terrlperature programming. The peaks were separated completely at retentiontime of 6.88min for chloroform, 8.21min for benzen, 10.38miu for trichloroethylen and 11.95minfor 1,4-dioxane. 2. Standard RSD were individually chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69%and 1,4-diorane 3.41%. 3. 60 samples were not detrcted chloroform, benzen, trichloroethylen and 1,4-dioxane.

課題의 特徵에 따른 兒童의 多重分類操作 發達樣相

李相魯,宋明子 慶北大學校 1980 論文集 Vol.30 No.-

This study aimed to illucidate the developmental aspects of children's multiplicative classification according to the number of attributes and the kind of drawings of the task. The hypotheses of the study were (1) The performance level of multiplicative classification will be defferent by children's age, number of attributes and kind of drawings of the task. (2) The developmental aspects of U-shaped curved in multiplicative classification will vary with the kind of drwings of the task (3) The developmental aspects of U-shaped curved in multiplicative classification will not vary with the number of attributes of the task. The subjects of the study were 120 children ranging from four to eight years of age, with 24 children for each age group. The tasks were 8 demonstration matrices and 40 test matrices. Test matrices were composed of 12 two-attribute geometric ones, 8 three-attribute geometric ones, 12 two-attribute realistic ones, and 8 three-attribute realistic ones. From the results and discussions of the study the following conclusions were obtained. 1. The overall performance level of multiplicative classification of children was different by age and the number of attributes of the task. Older children got higher scores except for the period between five and six years of age. Performance level was higher in the taskes of two attributes than in those of three attributes. Therefore the number of attributes of the task is an influential factor to the difficulty level of the task. 2. The overall performance level of multiplicative classification was not affected by the type of drawings of the tasks. This leads to a conclusion that the perceptual salience of the task according to the kind of drawings do not affect the performance level of the children of preoperational and concrete operational stage. 3. In the tasks of realstic drawings the performance level of five-year old children was higher than that of six-year olds, which is indicative of the developmental aspects of U-shaped curve. The same cannot be said of the geometric tasks. It follows that the perceptual effect of the tasks of realistic drawings is more salient than that of geometric taks, and that the effect is relevent only to five-year old children. 4. The performance level of five-year old children in the tasks of two attributes was higher than that of six-year olds, showing the U-shaped curve, but in three-attribute tasks the two age groups showed no difference. This shows that the perceptual effect of the symmetry of matrix tasks is more salient in the tasks of low difficulty level.

造景樹木의 葉內 硼素含量分布

李在奭,崔明子,金貞淑 대구효성 가톨릭대학교 1994 연구논문집 Vol.48 No.1

The distribution of boron on 98 different species of woody landscape plants which belonged to 38 different families were investigated. The soils used were Daegu Series developed out of Residiuum of Shale which is commonly found in Bongduk-dong, Daegu City and Hayang-eup, Kyungsan-gun, Kyungpllk Province. Some of the results obtained are summerized as follows : 1. Among the tested palnts, 33 species including European holly contained comparatively ow level of boron and 53 ones such as apple tree required medium level of boron for the normal growth. On the contrary, the rest of 9 species including Manshurian fullmoon maple accumulated much high level of boron for the normal growth. 2. Among the tested plants, tree of heaven contained the highest level of boron(90.4±0.15ppm) while arrow bamboo contained the lowest one(5.3±0.79ppm) 3. No significant correlation between the single leaf area and the boron content of the leaves was recognized when the area of the single leaf is less than 100㎠ but highly significant correlation(r=0.769**) between above two characters was recognized when that is over 100㎠/leaf. 4. when the tested plants were classified by the content of boron in the leaves, the rate of plants having the contents of 5∼10ppm, 10∼20ppm, 20∼30ppm, 30∼40ppm, 40∼50ppm, 50∼60ppm, and over 60ppm were 1%, 35.8%, 29.6%, 23.5%, 5.1%, 2.0%, and 3.0% respectively. 5. No significant correlation(r=0.072) between the content of boron in the soils naturally developed out of Shale and the content of boron in the leaves tested was recognized.

흰쥐 망막에서 발생시기에 따른 GABA성 및 Dopamine성 신경원의 분포양상과 이들신경원에서 GABA와 Dopamine의 공존양상

오수자,이문용,천명훈 대한해부학회 1995 Anatomy & Cell Biology Vol.28 No.6

뇌졸중 환자에서 꿈의 기억에 대한 반구의 편측성

이규용,이민자,김명호 한양대학교 의과대학 2002 한양의대 학술지 Vol.22 No.1

Background : Investigations of dream recall in cerebral vascular insults have shed some light on the controversial issue of cerebral hemispheric lateralization of dreaming. The goal of this is to provide a better understanding of the role of the cerebral hemisphere in dream recall. Methods : Dream recall was evaluated by means of a simple questionnaire carried out every out-patients 6 or 12 consecutive months in previous cerebral vascular insults patients. Patients with bilateral cerebral lesion or brainstem lesion were excluded. Study subjects included 98 patients ; 57 patients who had left hemispheric vascular insults and 41 patients who had right hemispheric vascular insults, based on the location of vascul insults on computed tomogram or magnetic resonance imaging. Results : Disturbance of dream recall were 59.6% in left hemispheric lesion, 24.4% in right hemispheric lesion. Intact dream recaller in left hemispheric lesion had minimal neurologic sequels. Conclusions : These findings are suggestive of that dream recall may be not a right hemispheric function, and left hemisphere may be more contributive. In addition, the presence of dream recall could be another good prognostic factor or evidence in cerebral vascular insults.

기니픽 망막 신경원에서 Dopamine과 GABA의 공존

천명훈,오수자,이문용,정진웅 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.1

전침 자극에 의한 오디 괄약근 운동성 변화에 관한 연구

이성구,김명완,김홍자,서동환,이상수,김동일,유교상,주연호,민병일,김지훈 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

Background/Aims: This study was designed to evaluated the effects of electroacupuncture on the sphincter of Oddi (SO) motility in humans and to correlate the manometric findings with plasma cholecystokinin (CCK) levels. Methods: Eleven patients (M: F= 5: 6) who had various kinds of biliary disorders were enrolled. SO motility was monitored with a conventional low-compliant continuously perfused technique using ERCP (n=9) or percutaneous transhepatic cholangioscope (n=2). After baseline monitoring for phasic wave contractions of SO, electroacupuncture was applied at a specific acupoint, GB 34, in these 11 patients. A nonspecific acupoint 5 cm away from GB 34 was selected as a control. Manometric parameters of SO were also checked in 6 subjects during stimulation of the control acupoint. CCK plasma levels were measured during the time course of electroacupuncture stimulation. Result: All the manometric parameters including the basal pressure of SO, amplitude, frequency and duration of phasic wave contraction of SO were significantly decreased (p< 0.05) during electroacupuncture stimulation. The inhibition of SO contractility was accompanied by increased CCK plasma levels. After removal of electroacupuncture stimulation, restoration of amplitude and duration to basal condition were noted. A tendency towards the return of SO contractility was also observed in basal pressure and frequency. Stimulation of the control acupoint, however, did not affect the SO contractility and plasma CCK levels. Conclusions: Electroacupuncture stimulation of acupoint GB 34 showed reversible inhibition of SO contraction in humans. We speculate that the response of SO to electroacupuncture stimulation may be mediated by some neurohormonal mechanisms including CCK release. (Korean Journal of Gastrointestinal Motility 2000;6:44-41)

임하댐 탁수지역에 서식하는 잉어의 조직과 혈장단백질의 변화

이청,신명자,김경호,박진영,이종은,서을원 7개 국립대학교 환경연구 논문집 공동발행 위원회 2004 공업기술연구 Vol.4 No.-

Present study is aimed to investigate the effect of muddy water in lmha Dam on various tissues and plasma proteins of carp. Cyprinus carpio. The gills in muddy water were appeared to have clubbing and edema in secondary lamellac and primary lamellac respectively. The sizes of glomerula in kidney were lessened smaller rather then those of in Andong Dam but the thickness of integument was becoming broader. Scanning electron micrographs of gills showed that muddy debris and parasites were attached to between primary and secondary lamcllac, suggesting that muddy water are invloved the possibility to lower the respiratory rate. By using SDS-PAGE 42 Kda plasma protein was identified only in carp plasma of muddy water and plasma protein bands were shown both quantitative and qualitative changes . Ferritin activity was observed more strong and Fe-1 was appeared to specific to in carp plasma of muddy water.

체육전공대학생들의 신체적 자기효능감과 스포츠 가치관의 관계 연구

이명자 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The purpose of this study was to investigate the relationships between physical self-efficacy and sports values of university students. Responses from a total of 271 subjects were analyzed using correlation, t-test and ANOVA. The findings from the study were as follows; First, when using total subjects regardless of their major, there were statistically significant positive correlation between physical self-efficacy and sports values. Especially physical values were closely related to physical self-efficacy. This means that the more physical self-efficacy tendency a person has, the stronger he(she) is his(her) physical value-oriented. Second, significant differences were found between majors in physical self-efficacy and sports values. Students majoring in physical education have higher physical self-efficacy and sports values, as expected. Third, when analyzed using physical education major students" data only, significant gender differences on physical self-efficacy and sports values were found. Significant differences were also found in sports values between social classes. But though there were differences between gender and social classes in physical self-efficacy and sports values, their scores were high in all domains, meaning students majoring in physical education have high level of awareness of physical self-efficacy and sports values.