하시모토 병과 동반된 악성 빈혈 1 예

한 호,안명주,최정혜,이창범,이영열,최일영,김인순,이웅수 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.2

Pernicious anemia is the most common cause of vitamin B12 deficiency and is caused by autoimmune destruction of parietal cell containing gastric mucosa region. This disease is significantly associated with autoimmune endocrinopathies and anti-receptor autoimmune disease. We report here a case of 26-year old man who was diagnosed pernicious anemia with high level of autoantibody titer (antithyroglobulin antibody 1:25,600 and antimicromosomal antibody 1:6,400) indicating subclinical Hashimoto's thyroiditis. Since other autoimmune diseases are frequently associated with pernicious anemia even without evidence of clinical symptoms, screening test for the presence of autoimmune disease should be evaluated in these patients.

膝關節腔 二重造影劑撮影法에 關한 硏究

金漢錫,趙明俊,李昌惠 최신의학사 1976 最新醫學 Vol.19 No.1

For last 3 years (1973-1975), Double contrast knee arthrography has been performed in 40 patients in the Radiologic department of the National Medical center. The results were as followings: 1) Sex distribution was male 25, female 15, and age ranged from 10 to 49. High incidence was noted in the 3rd decade. 2) In the majority, clinical symptom was knee joint pain. 3) The lesion was more frequent on the Right knee than on the left. 4) lateral meniscus tear (19 cases) was more frequent than the medical one (3 cases). 5) Double contrast Knee arthrography can disclose those lesions of the menisci, the articular cartilages, the synovium, and ligaments. 6) Diagnostic accuracy of double contrast knee arthrography is more than 95%, but authors obtained about 80%, probably due to unskillful technique and inaccurate interpretation. Batter technique and interpretation are necessitated.

金利스왑의 去來動機와 去來效果

趙明鎬,李海永,鄭漢珪 강남대학교 사회과학연구소 1998 사회과학논총 Vol.5 No.-

이동 열원을 고려한 전자빔 용접의 유한요소해석

조해용,정석영,김명한,조창용,이제훈,서정 한국레이저가공학회 2001 한국레이저가공학회지 Vol.4 No.1

Simulation on the electron beam welding of Al 2219 alloy was carried out by using commercial FEM code MARC, which encounters moving heat sources. Due to axisymmetry of geometry, a half of the cylinder was simulated. A coupled thermo-mechanical analysis was carried out and subroutine for heat flux was substituted in the program. The material properties such as specific heat, heat transfer coefficient and thermal expansion coefficient were given as a function of temperature and the latent heat associated with a given temperature range is considered. As a result, the proper beam power is 60kVX60mA and welding speed is 1~1.5 m/min. The residual stress in the heat-affected zone as well as the fusion zone does not increase. It is necessary to use jigs for preventing distortion of cylinder and improving weld quality.

循環 흐름을 가진 固定層 反應器의 不安定性에 관한 硏究

梁海永,韓道興,李明浩 嶺南大學校 工業技術硏究所 1993 工業技術硏究所論文集 Vol.21 No.1

In this study we observed the possible existence of multiple steady states for CO oxidation over Pt/Boehmite catalysts, which is one of instabilities, and also analyzed numerically these phenomena with some proper reactor models. The form of our reactor was a non-adiabatic fixed bed with recycle. The reactor models include both one phase model with plug flow and two phase model with heat transfer resistance between gas phase and solid one. Especially, it was attempted to explain the multiplicity features with a very wide region, whose features could not have been clearly explained by means of any other model, by the modified two phase model which includes a term related with memory effect of catalyst temperature. The experiments showed that the effect of recycle ratio on multiplicity region could not be revealed definitely for our experimental conditions. This may arise from the facts that the multiplicity for the CO oxidation over Pt/Boehmite cataysts resulted mainly from strong heat transfer limitation rather than from mixing effect related with recycle flow since the CO oxidation was a reaction with both very high generation and rapid reaction rate.

만성 승모판 패쇄부전증 환자에서의 안지오텐신 전환효소 억제제의 장기 투여 효과

김대희,이명묵,이해영,조현재,박승정,서재빈,서정원,양한모,윤창환,조상호,이준희,김용진,김명아,손대원,오병희,박영배 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

두경부 암환자의 항암화학요법에 따른 삶의 질 변화

신혜숙,박혜자,박명희,연기순,김훈교,문한림,송혜향 가톨릭대학교 가톨릭대학교 간호대학 호스피스 교육연구소 1999 호스피스논집 Vol.4 No.-

The purpose of this study was to assess the changes in quality of life wish elapse of chemotherapy in head and neck cancer patients. This study was a longitudinal descriptive design. The subjects were 9 patients who had stage III and stage IV head and neck cancer and received neoadjuvant cisplatin and 5-fluorouracil chemotherapy. Linear Analogue Self Assessment Scale (LASA) of the QOL which it includes eleven items(seven physical items appetite, nausea/vomiting, physical well-being, vigor activity, energy, sleepiness, fatigue and four mental items anger, anxiety, depression & vital power) were used to assess the quality of life eleven times(once in the prechemotherapy period and from the 1st day to 10th day postchemotherapy). The means of scores at each time were analyzed by repealed measures of ANOVA and Bonferroni multiple comparison method. The results are as follows : 1. The degree of appetites decreased significantly on the period between third and sixth day compared with that of appetites on the prechemotherapy day (p<0.001). 2. The degree of physical well-being decreased significantly on the period between first and fifth day compared with that of physical well-being on the prechemotherapy day (p<0.001). 3. The degree of nausea/vomiting decreased significantly on the period between first and fourth day compared with that of appetites on the prechemotherapy day (p<0.001). 4. The degree of anger decreased significantly on the second, fourth, eighth and ninth day after chemotherapy compared with that of anger on the prechemotherapy day(p<0.001). 5. The degree of fatigue decreased significantly on the fourth day compared with that of fatigue on the prechemotherapy day(p<0.001). 6. The increment of nausea/vomiting and poor appetite started on the 2.89th day and 3.67th day after chemotherapy, respectively. 7. The increment of sleepiness started on the 2.56th day after chemotherapy. 8. The increment of depression and anxiety started on the 2.33th day and 3.33th day after chemotherapy, respectively. 9. The lowest degrees of nausea/vomiting and poor appetite were 37.00±17.9 % and 28.64±14.94 % after chemotherapy compared with those of nausea/vomiting and poor appetite on the prechemotherapy day, respectively. 10. The lowest degrees of anger and vigor activity were 48.12±28.3 % and 39.83±24.9 % after chemotherapy compared with those of anger and vigor activity on the prechemotherapy day, respectively. 11. The recovery rates of eight items of quality of life (appetite, vigor activity, energy, fatigue, anger, anxiety, depression & vital power) were shown to reach a peak on the tenth day after chemotherapy and be reached to almost 84 % compared with those of quality of life on the prechemotherapy day. 12. The recovery rates of physical well-being and sleepiness were shown to reach to 67.75 % and 95.68 % on the 10th day after chemotherapy compared with those of physical well-belong and sleepiness on the prechemotherapy day. 13. The recovery rates of seven physical items were faster than those of four mental items on the 10th day after chemotherapy. In conclusion, it is suggested that nursing care strategies to improve the quality of life in patients with chemotherapy would be established both physically and mentally, and be extended at least ten days when patients stayed their home after chemotherapy.

순무(Brassica campestris ssp. rapa) 뿌리로부터 지질화합물의 분리 및 동정

방면호,오영준,유종수,한민우,정해곤,정태숙,최명숙,이경태,김세영,백남인 경희대학교식량자원개발연구소 2007 硏究論文集 Vol.26 No.1

순무 뿌리로부터 활성 물질을 분리 동정 하기 위하여 80% MeOH 수용액으로 추출하고 이를 여과, 감압 농축하여 MeOH추출물을 얻었다. 이를 EtOAc분획, n-BuOH분획, H_(2)O분획으로 나누었으며, EtOAc분획에 대해 silica gel column chromatography를 실시하여 3종의 지질화합물을 분리 정제하였다. ^(1)H-NMR, ^(13)C-NMR, DEPT spectrum 및 Mass spectrum등을 통하여 palmitic acid methyl ester(compound 1), linolenic acid methyl ester(compound 2), linoleic acid methyl ester(compound 3)으로 구조를 결정하였다. In order to isolate and identify the active compound from the Brassica campestris ssp rapa, the roots and the root skin were extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH and H_(2)O. From the EtOAc fraction, three compounds were isolated through the repeated silica gel column chromatographies. From the result of spectral data including NMR and MS, the chemical structures of the compound were determined as palmitic acid methyl ester (compound 1), linolenic acid methyl ester (compound 2), linoleic acid methyl ester (compound 3).

청주대학교 간호학과 교육과정 개발 연구

안경주 김철규 전해옥 김봉정 김혜숙 채명옥 윤현정 한달롱 김아린 청주대학교 보건의료과학연구소 2014 보건의료과학연구 Vol.3 No.1

Dynamics in the workplace and in society have contributed to the paradigm shift to outcome-based education. This study was performed to develop the curriculum based on assessment of existing program for the baccalaureate nursing program at Cheongju University. We used three steps-Analysis, Design, and Development-in ADDIE model for developing curriculum. The subjects were 18 graduate nurses, 41 nursing students, 38 parents, and 2 nursing team leaders for analysis of core competence. In conclusion, developing an outcome-based curriculum might be used to facilitate the students' development and evaluate the competence of the student during and on completion of the nursing baccalaureate program at Cheongju University.

The Effects of Sc on the Microstructure and Mechanical Properties of Hypo-Eutectic Al-Si Alloys

Myung Han Kim,Young Myung Hong,Hae Yong Cho 대한금속학회 2004 METALS AND MATERIALS International Vol.10 No.6