Distribution of Bi–MnS Inclusions Existing in 1215MS Steels: Correlation with Thermal Physical Coefficient

Jian‑bo Xie,Bei‑bei Liu,Xiang‑yu Wu,Jian‑xun Fu 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.5

This work aims to comprehensively summarize the types and distribution of the isolated Bi particles and MnS inclusions inthe Bi-bearing steels, to study the precipitated behavior of sulfide, and to study the effect of Bi particles on grain sizes andthe volume thermal expansion coefficients of the steels. Results show that the average percentage of the isolated Bi particles,semi-encapsulation, complete encapsulation, back-bridge, tiny encapsulation, cavity bridge Bi–MnS inclusions in the Bibearingsteels was 16.89%, 20.49%, 3.44%, 16.89%, 31.63%, 10.66%, respectively. The average equivalent diameters of thegrains in the 0 ppm, 130 ppm, 240 ppm, 760 ppm, 1200 ppm and 2300 ppm Bi content steels were 20.88, 20.17, 19.54, 18.13,13.98 and 13.25 μm, respectively. The precipitated equilibrium mass concentration product of the MnS (w[Mn]·w[S]) wascalculated to be 1.07, and the solid fraction fS value was 0.61. At 950 °C, the volume thermal expansion coefficient change(ΔVE) in 760 ppm Bi content steel was minimum 4 × 10–10%, while at 461.6 °C the ΔVE was maximum, 0.09%, which meansthat Bi affected the volume thermal expansion of the steel strongest in this temperature range.

Analysis of Geographic and Pairwise Distances among Chinese Cashmere Goat Populations

Liu, Jian-Bin,Wang, Fan,Lang, Xia,Zha, Xi,Sun, Xiao-Ping,Yue, Yao-Jing,Feng, Rui-Lin,Yang, Bo-Hui,Guo, Jian Asian Australasian Association of Animal Productio 2013 Animal Bioscience Vol.26 No.3

This study investigated the geographic and pairwise distances of nine Chinese local Cashmere goat populations through the analysis of 20 microsatellite DNA markers. Fluorescence PCR was used to identify the markers, which were selected based on their significance as identified by the Food and Agriculture Organization of the United Nations (FAO) and the International Society for Animal Genetics (ISAG). In total, 206 alleles were detected; the average allele number was 10.30; the polymorphism information content of loci ranged from 0.5213 to 0.7582; the number of effective alleles ranged from 4.0484 to 4.6178; the observed heterozygosity was from 0.5023 to 0.5602 for the practical sample; the expected heterozygosity ranged from 0.5783 to 0.6464; and Allelic richness ranged from 4.7551 to 8.0693. These results indicated that Chinese Cashmere goat populations exhibited rich genetic diversity. Further, the Wright's F-statistics of subpopulation within total (FST) was 0.1184; the genetic differentiation coefficient (GST) was 0.0940; and the average gene flow (Nm) was 2.0415. All pairwise FST values among the populations were highly significant (p<0.01 or p<0.001), suggesting that the populations studied should all be considered to be separate breeds. Finally, the clustering analysis divided the Chinese Cashmere goat populations into at least four clusters, with the Hexi and Yashan goat populations alone in one cluster. These results have provided useful, practical, and important information for the future of Chinese Cashmere goat breeding.

Apoptosis-inducing effect and structural basis of Polygonatum cyrtonema Lectin and chemical modification properties on its mannose-binding sites

( Bo Liu ),( Xiao Chao Xu ),( Yan Cheng ),( Jian Huang ),( Yan Hong Liu ),( Zhen Liu ),( Ming Wei Min ),( He Jiao Bian ),( Jing Chen ),( Jin Ku Bao ) 생화학분자생물학회 2008 BMB Reports Vol.41 No.5

Clinicopathologic Characteristics and Prognostic Factors in Patients with Operable HER-2 Overexpressing Breast Cancer

Liu, Ai-Na,Sun, Ping,Liu, Jian-Nan,Ma, Jin-Bo,Qu, Hua-Jun,Zhu, Hua,Yu, Cai-Yan,Zhang, Liang-Ming Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Objective: To study the relationship between clinical pathologic characteristics, treatment modalities and prognostic factors in HER-2 (Human Epidermal growth factor Receptor-2) overexpressed breast carcinoma. Materials and Methods: Major clinico-pathological factors including therapeutic modalities and survival status of 371 breast cancer patients with HER2 over-expression, teated at Yantai Yuhuangding Hospital from March of 2002 to December of 2010 were retrospectively studied, with special attention focused on survival-related factors. Results: The median age of the total 371 patients in this study was 48 years at time of diagnosis, among which, the leading pathological type was infiltrating ductal carcinoma (92.5%); 62.8% presented with a primary tomor larger than 2 cm in diameter at diagnosis, 51.0% had axillary lymph node (ALN) metastases; ER (Estrogen receptor)/PR (Progesterone receptor) double negative occured in 52.8% of cases, and PCNA (proliferation cell nuclear antigen) (+++) was found in 55.1%. HER-2 overexpressed patients were usually in advanced stage when the diagnosis was made (72.8% at stages IIA~IIIC). The prognosis and survival were assessed in 259 patients with complete follow-up data. 5-year DFS (disease-free survival) and OS (overall survival) rate was 68.0% and 78.0% respectively. Univariate analysis revealed that age, tumor size, ALN metastases, LVSI (lymph-vascular space involvement), PCNA status, hormonal therapy, chemotherapy cycles, and HER-2 overexpression, correlated closely with the prognosis. ALN metastases, LVSI, PCNA status and chemotherapy cycles were independent predictors of survival. Conclusions: HER-2 overexpressed breast cancer has special clinical and pathological characteristics, with advanced clinical stages and high rate of ER/PR double negative. Lymph node metastases, LVSI, PCNA and chemotherapy cycles are independent predictors of prognosis.

MULTIPLE PERIODIC SOLUTIONS OF p-LAPLACIAN EQUATION WITH ONE-SIDE NAGUMO CONDITION

Jian Jun Zhang,Wen Bin Liu,Jin Bo Ni,Tai Yong Chen 대한수학회 2008 대한수학회지 Vol.45 No.6

In this paper, the existence and multiplicity of solution of periodic solutions of p-Laplacian boundary value problem are studied by using degree theory and upper and lower solutions method. Some known results are improved. In this paper, the existence and multiplicity of solution of periodic solutions of p-Laplacian boundary value problem are studied by using degree theory and upper and lower solutions method. Some known results are improved.

Characteristics of Diprophylline-Induced Bidirectional Modulation on Rat Jejunal Contractility

Liu, Fang-Fei,Chen, Da-Peng,Xiong, Yong-Jian,Lv, Bo-Chao,Lin, Yuan The Korean Society of Pharmacology 2014 The Korean Journal of Physiology & Pharmacology Vol.18 No.1

In this study, we propose that diprophylline exerts bidirectional modulation (BM) on the isolated rat jejunal segment depending on its contractile state. The results supported the hypothesis. Diprophylline ($20{\mu}M$) exerted stimulatory effects on the contractility of jejunal segment in six low contractile states while inhibitory effects in six high contractile states, showing the characteristics of BM. Diprophylline-induced stimulatory effect was significantly blocked by atropine, indicating the correlation with cholinergic activation. Diprophylline-induced inhibitory effect was partially blocked by phentolamine, propranolol, and L-N-Nitro-Arginine respectively, indicating their correlation with sympathetic activation and nitric oxide-mediated relaxing mechanisms. Diprophylline-induced BM was abolished by tetrodotoxin or in a $Ca^{2+}$ free condition or pretreated with tyrosine kinase inhibitor imatinib, suggesting that diprophylline-induced BM is $Ca^{2+}$ dependent, and that it requires the presence of enteric nervous system as well as pacemaker activity of interstitial cells of Cajal. Diprophylline significantly increased the reduced MLCK expression and myosin extent in constipation-prominent rats and significantly decreased the increased MLCK expression and myosin extent in diarrhea-prominent rats, suggesting that the change of MLCK expression may also be involved in diprophylline-induced BM on rat jejunal contractility. In summary, diprophylline-exerted BM depends on the contractile states of the jejunal segments, requires the presence of $Ca^{2+}$, enteric nervous system, pacemaker activity of interstitial cells of Cajal, and MLCK-correlated myosin phosphorylation. The results suggest the potential implication of diprophylline in relieving alternative hypo/hyper intestinal motility.

Scandium-doped barium ceria ferrites-based composite mixed conducting hollow fiber membranes for H2 and O2 permeation

Jian Song,Claudia Li,Shao Zhang,Kai Wang,Bo Meng,Xiaoyao Tan,Jaka Sunarso,Shaomin Liu 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.107 No.-

BaCeO3-based ceramics are a unique class of perovskites that exhibit protonic and oxygen ionic conduction,which are ideal for high temperature hydrogen separation applications. This work features Sc-dopedBCFe composites with nominal composition of BaCe0.70Fe0.30-xScxO3d (BCFSc) (x = 0, 0.05, 0.1, 0.15, and0.2) that exhibit enhanced thermal, chemical, and mechanical stability. The BCFSc20 (x = 0.20) hollowfiber membranes demonstrated the highest hydrogen and oxygen fluxes among the Sc-doped compositesof up to 0.32 and 0.20 mL min1 cm2, respectively, at 1000 C. The BCFSc20 hollow fibers also displayedexcellent stability under the hydrogen and oxygen permeation environments, while the permeation performanceof the other BCFSc samples with low Sc content gradually deteriorated over the 120-h stabilitytest.

A Survey on the Establishment and Application of Social Capital Partner Selection System for the New Profit PPP Project

Bo Liu,Ju-qin Shen,Zhao-jian Meng,Fu-hua Sun 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.10

As the economy in China enters the new normal, Public-Private Partnerships have been an important measure for alleviating financial tensions and improving the administrative efficiency of the government. Based on the mode of open tendering for the selection of social capital partners for the new profit project, the open tendering procedures were analyzed. In addition, based on an improved TOPSIS model, the evaluation index system for the selection conducts a comprehensive evaluation of six aspects: reputation and performance, water pricing factor, financing program, construction program, operation and maintenance program, and transfer program.

Quantitative Reduction of Basilar Invagination With Atlantoaxial Dislocation by a Posterior Approach

Jian Guan,Fengzeng Jian,Qingyu Yao,Chenghua Yuan,Can Zhang,Longbing Ma,Zhenlei Liu,Wanru Duan,Xingwen Wang,Xuefeng Bo,Zan Chen 대한척추신경외과학회 2020 Neurospine Vol.17 No.3

Objective: This study evaluated the feasibility and efficacy of quantitative reduction and fixation to treat basilar invagination (BI) with atlantoaxial dislocation (AAD). Methods: Posterior occipitocervical angle (POCA), occiput–C2 angle (Oc–C2A), clivusaxial angle (CAA), and C2–7 angle (C2–7A) were considered for quantitative reduction. Twelve patients with BI complicated with AAD received posterior interarticular release and individualized cage implantation to restore vertical dislocation. The POCA was adjusted using cantilever technology to further reduce the horizontal dislocation and adjust lower cervical vertebral angle. All patients received a radiological follow-up for ≥12 months. Improvements in spinal cord function were evaluated using Japanese Orthopedic Association (JOA) score. Results: All the patients received successful quantitative reduction for BI-AAD, and bony fusion was achieved without spinal cord injury after surgery for 12 months. The JOA score was improved significantly to 15.2 ± 0.9 twelve months after surgery (p < 0.01). Radiological follow-up revealed that individualized cage and POCA play vital roles in quantitative correction: (1) distance of the dens above McRae’s line and atlantodens interval were restored to normal level, respectively; (2) changes in Oc–C2 angle (ΔOc–C2A), C2–7 angle (ΔC2–7A), clivus-axial angle (ΔCAA), and POCA (ΔPOCA) were all caused by changes in axis tilt. Based on the changes of radiological parameter we deduced the formula for quantitative reduction by linear regression analysis: -ΔPOCA = ΔOc–C2A = -ΔC2–7A = ΔCAA. Conclusion: Quantitative posterior reduction by individualized cage and adjusting ΔPOCA is feasible for treating BI with AAD.

Plastic Deformation Mechanism of the Ti6Al4V Micro-gear Formed Under an Electrical Field

Bo Zeng,Xiangzhong Yan,Zhiqiang Xie,Jian Liu,Jie Wang,Kunlan Huang,Yi Yang 한국정밀공학회 2024 International Journal of Precision Engineering and Vol.11 No.1

Despite the fact that titanium alloy micro-gear has superior performance and can withstand special conditions, it is difficult to machine due to its poor plasticity and high strength. We proposed an eco-friendly, efficient, and sustainable electric field assisted micro-plastic forming technology (micro-EFAPFT) for forming titanium alloy microparts. Ti-6Al-4 V alloy bars were extruded into micro-gears using an electrothermal coupling field and Joule heating in a graphite mold. The micro-gear has high precision, good surface quality, and a simple process. The whole process takes only 380 s. The findings demonstrate that the best gear forming degree, fewer microstructure defects, and hardness reaching 330.1 HV—4.4% higher than that of the raw material—occur when the pressure holding period is 120 s. During the plastic deformation process, phase transformation and recrystallization occur, increasing the fraction of α phase from 96.6–99.68% and increasing the grain orientation difference. The tooth tip has finer grains but longer dislocation lines. In conclusion, the electric field accelerates dislocation motion, reduces dislocation density, and increases material plasticity, allowing the Ti6Al4V micro-gear to be formed in a single step. The experimental results validate the feasibility of this technology for producing titanium alloy micro-gear and can be used to guide the production of different materials and shapes of microparts.