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      • KCI등재

        A Study of the Content Validity of Reading Comprehension Tests in NMET II

        Zhen-Jie Liu,Ming-Hao Jin 대한언어학회 2018 언어학 Vol.26 No.4

        Liu, Zhen-Jie & Jin, Ming-Hao. (2018). A study of the content validity of reading comprehension tests in NMET II. The Linguistic Association of Korea Journal, 26(4), 103-124. Based on Bachman and Palmer’s (1996) framework of task characteristics, this paper aims to compare the reading comprehension tests of the 2013-2017 National Matriculation English Test II (NMET II) with the requirements of the New Curriculum Standards and Testing Syllabus, in particular, concerning the content validity of the tests in terms of the characteristics of input and expected responses. The implications of this study are discussed for test designers, teachers, and students. The results show that reading comprehension tests from 2013 to 2017 basically meet the requirements of the New Curriculum Standard and Testing Syllabus and have a high content validity. In terms of the characteristics of input, the length, reading speed, and readability of comprehension passages are appropriate for students; however, the distribution of topics and genres in each year is uneven. In terms of the characteristics of expected responses, the wordings of questions and the design of question items are reasonable. However, the response type is mainly restricted to selected response questions (multiple-choice), and the measure of reading skills coverage is unbalanced.

      • SCIESCOPUSKCI등재

        Synergistic Effect of Bone Marrow-Derived Mesenchymal Stem Cells and Platelet-Rich Plasma in Streptozotocin-Induced Diabetic Rats

        ( Zhen Zhen Lian ),( Xiao Jing Yin ),( Hua Li ),( Li Li Jia ),( Xiu Zhen He ),( Yong Bo Yan ),( Nai Hua Liu ),( Ka Yiu Wan ),( Xiao Kun Li ),( Shao Qiang Lin ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.1

        Background: Diabetic wounds are a major clinical challenge, because minor skin wounds can lead to chronic, unhealed ulcers and ultimately result in infection, gangrene, or even amputation. Studies on bone marrow derived mesenchymal stem cells (BMSCs) and a series of growth factors have revealed their many benefits for wound healing and regeneration. Platelet-rich plasma (PRP) may improve the environment for BMSC development and differentiation. However, whether combined use of BMSCs and PRP may be more effective for accelerating diabetic ulcer healing remains unclear. Objective: We investigated the efficacy of BMSCs and PRP for the repair of refractory wound healing in a diabetic rat model. Methods: Forty-eight rats with diabetes mellitus induced by streptozotocin were divided into four groups: treatment with BMSCs plus PRP, BMSCs alone, PRP alone, phosphate buffered saline. The rate of wound closure was quantified. A histopathological study was conducted regarding wound depth and the skin edge at 7, 14, and 28 days after surgery. Results: Wound healing rates were significantly higher in the BMSC plus PRP group than in the other groups. The immunohistochemistry results showed that the expression of platelet/endothelial cell adhesion molecule 1, proliferating cell nuclear antigen, and transforming growth factor-β1 increased significantly in the BMSC plus PRP group compared to the other treatment groups. On day 7, CD68 expression increased significantly in the wounds of the BMSC plus PRP group, but decreased markedly at day 14 compared to the controls. Conclusion: The combination of BMSCs and PRP aids diabetic wound repair and regeneration. (Ann Dermatol 26(1) 1∼10, 2014)

      • KCI등재
      • KCI등재

        Research on Vibration Saltation of the Transformer Core Caused by DC Bias of Based on Empirical Mode Decomposition

        Zhen Shaoming,Liu Chenliang,Liu Xingmou 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.2

        This paper presents a time–frequency analysis of the vibration of transformer under direct current (DC) bias through Hilbert– Huang transform (HHT). First, the empirical mode decomposition (EMD) process, which is the key in HHT, was introduced. The results of EMD, namely, intrinsic mode functions (IMFs), were calculated and summed by Hilbert transform (HT) to obtain time-dependent series in a 2D time–frequency domain. Next, the theory of DC bias for the transformer was analyzed. In consideration of the DC bias eff ect and in combination with the existing transformer vibration-related mechanism, the electromagnetic force equations of the transformer core were deduced. Lastly, a test system of vibration measurement for the transformer was set up. Three direction (x, y, and z axes) components of core vibration were measured. Decomposition of EMD and HHT spectra showed that vibration strength increased, and odd harmonics were produced with DC bias. This method illustrates the most obvious vibration distortion in the z-axis direction when the transformer is DC biased. Among them, the distortion of IMF3 has increased by more than 5 times. However, the distortion in the x-axis and y-axis directions also exists, but it is not obvious. Especially, 50 Hz component appeared in z-direction, 50 Hz component increased twofold in y-direction, and 150 Hz component increased threefold in z-direction. Results indicated that HHT can not only provide the occurrence time of DC bias but can also obtain the signal change components of the transformer vibration. Thus, HHT is a viable signal processing tool for transformer health monitoring.

      • KCI등재

        Experimental study on multi-level overtopping wave energy convertor under regular wave conditions

        Zhen Liu,Zhi Han,Wanchang Yang 대한조선학회 2018 International Journal of Naval Architecture and Oc Vol.10 No.5

        A multi-level overtopping wave energy converter was designed according to the large tidal range and small wave heights in China. It consists of two reservoirs with sloping walls at different levels. The reservoirs share a common outflow duct and a low-head axial turbine. The experimental study was carried out in a laboratory wave-flume to investigate the overtopping performance of the device. The depth-gauges were used to measure the variation of the water level in the reservoirs. The data was processed to derive the time-averaged overtopping discharges. It was found that the lower reservoir can store wave waters at the low water level and break the waves which try to climb up to the upper reservoir. The upper sloping angle and the opening width of the lower reservoir both have significant effects on the overtopping discharges, which can provide more information to the design and optimization of this type of device.

      • KCI등재

        Long non-coding RNA HOTAIR promotes hepatocellular carcinoma progression by regulating miR-526b-3p/DHX33 axis

        Liu Zhen,Ouyang Guoqing,Lu Wuchang,Zhang Huiming 한국유전학회 2021 Genes & Genomics Vol.43 No.8

        Background Hepatocellular carcinoma (HCC) is one of the most common human cancers. Long non-coding RNAs (lncRNAs) play pivotal roles in progression of various cancers, including HCC. Objective We aimed to explore the exact role and underlying mechanism of lncRNA HOX transcript antisense intergenic RNA (HOTAIR) in HCC. Methods Quantitative real time polymerase chain reaction (qRT-PCR) was carried out to determine the levels of HOTAIR, DEAH-box helicase 33 (DHX33) and miR-526b-3p. Western blot assay was used to detect the protein level of DHX33. Besides, cell proliferation and apoptosis were assessed by methylthiazolyldiphenyl-tetrazolium bromide (MTT) assay and fow cytometry analysis, respectively. Cell migration and invasion were detected by transwell assay. The interaction between miR-526b-3p and HOTAIR or DHX33 was predicted by starbase and confrmed by the dual-luciferase reporter assay. Murine xenograft model was established through injecting Huh7 cells transfected with sh-NC or sh-HOTAIR. Results The levels of HOTAIR and DHX33 were increased in HCC tissues and cells. Knockdown of either HOTAIR or DHX33 suppressed proliferation, migration and invasion but increased apoptosis in HCC cells. Moreover, DHX33 overexpression reversed the suppressive efect of HOTAIR knockdown on progression of HCC cells. Interestingly, miR-526b-3p could directly bind to HOTAIR, and DHX33 was a direct target of miR-526b-3p. Additionally, interference of HOTAIR restrained the tumor growth by upregulating miR-526b-3p and downregulating DHX33 in vivo. Conclusions HOTAIR knockdown suppressed cell proliferation, migration and invasion, and promoted apoptosis via regulating miR-526b-3p/DHX33 axis in HCC cells, providing a potential avenue for treatment of HCC.

      • 휴대용 게임기 구매의도에 영향을 미치는 요인에 관한 한중 비교연구

        LIU ZHEN,강유리,박철 한국경영정보학회 2010 한국경영정보학회 학술대회논문집 Vol.2010 No.1

        첨단제품의 하나인 휴대용 게임기는 언제 어디서나 멀티미디어 콘텐츠를 활용할 수 있는 유비쿼터스를 기반으로 급속히 발전하고 있다. 본 연구에서는 휴대용 게임기를 대상으로 소비자의 구매의도에 영향을 미치는 요인이 무엇인지 한국과 중국의 소비자를 비교하였다. 사용된 변수는 크게 휴대용게임기 혜택요인과 소비자요인이었다. 그 결과, 한국과 중국에서 모두 시간활용성, 유행추구성, 소비자혁신성, 가격민감성, 그리고 주관적 규범은 게임기 구매의도에 유의한 영향을 미치는 것으로 나타났다. 그러나 조작편리성, 인지된 즐거움, 진부화 위험 등이 게임기 구매의도에 미치는 영향은 중국과 한국에서 유의한 차이가 나타났다. 본 연구 결과의 이론적 시사점으로는 향후 국가 간 휴대용 게임기의 구매의도에 관한 연구를 하는데 도움이 될 것이고, 실무적 시사점으로는 휴대용 게임기를 비롯한 첨단제품 사용에 관한 중국 소비자들의 구매의도를 파악하는데 도움이 될 것이다.

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