한국인 인슐린 비의존형 당뇨병 및 이차성 당뇨병 환자에서 글루코키나제 유전자 변이

남재현(Jae Hyun Nam),이현철(Hyun Chul Lee),김연의(Youn Euy Kim),권석호(Suk Ho Kwon),윤용석(Yong Suk Yoon),박석원(Suk Won Park),원영준(Young Jun Won),차봉수(Bong Su Cha),송영득(Young Duk Song),이은직(Eun Jig Lee),임승길(Sung Kil Lim) 대한내과학회 1998 대한내과학회지 Vol.54 No.6

N/A Objectives: Mutations in the glucokinase (GCK) gene are considered a possible cause of maturity-onset diabetes of the young. The purpose of this study was to evaluate the contribution of this gene to the development of non insulin dependent diabetes mellitus (NIDDM), gestational diabetes mellitus (GDM) and post-renal transplantation diabetes mellitus (PTDM). Method: Identification of GCK mutation was attempted on 39 NIDDM patients, 2 GDM patients and 58 selected renal allograft recipients with PTDM and 45 normal controls. The exons in the GCK gene were examined by polymerase chain reaction (PCR), followed by analysis of single-stranded DNA conformational polymorphism (SSCP). The abnormal bands were also confirmed by DNA sequencing analysis. The exons of affected family members were also investigated for mutations of the GCK gene. Results: Two of the 58 PTDM patients (3.4%) were found to have CKK mutations. One had the mutation on exon 5 and the other on intron 7. One control subject had the mutation on intmn 9. The mutation of exon 5 was identified as a substitution of CCT (proline) for CTT (leucine) at codon 164, which has not ever reported before. The family members of the PFDM patient with mutation of exon 5 were analyzed by PCR followed by SSCP, and two of them revealed the same mutation. The abnormal band on the SSCP analysis of exon 7 was identified as the insertion of base C/T at the 39th nucleotide in intron 7. Two family members of this patients also had same band on SSCP. The one mutation of 45 normal controls was CT located at the 8th nucleotide in intron 9, which was a common polymorphism. Conclusion: We found GCK mutations in subjects with PTDM and we speculate that these mutations may be one of the contributing cause of PTDM.

본딩 웨이퍼 검사를 위한 모델링 연구

임영환,양시은,장동영,안효석,홍석기 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

본 논문에서는 레이저 빔 투과를 이용한 본딩 웨이퍼 검사 방법을 제안하고 검사 장치를 설계 구현하였다. 1064nm파장에서의 정상웨이퍼를 일정한 비율로 투과하였다. 본딩 불량으로 인한 웨이퍼의 기공은 두께에 따라 투과율이 현저하게 변화하여 기공 부분을 검출하였다. 이러한 기공은 두께의 변화가 있으며 광량의 변화하는 부분이 에어갭으로 인식 카메라로 쉽게 구분이 가능하였다.

아시아 경기대회의 서구화와 그 반성

임영무,안희숙 한국체육사학회 2001 체육사학회지 Vol.7 No.-

We together had a chance to think over the subject of Asian Games. It may looks issuance of regionalism or nationalism against the current on of globalization however, in order to find the ways for the further development of the spirit of Asian Games, it is believed that it's time to open the discussion on it. We also did put efforts to search the next deploying goals of the Asian Games, while reviewing both positive and negative aspects of the Games through the chronological investigation of Asian Games history, and researching the situational aspects of pre-modern and modern Asian sports. Thinking over the two aspects, positive and negative viewpoints, of the general effects of the Asian Games to Asian sports, the 4 positive effects of Asian Games may be pointed out ; ①that Asian Games affected to solidify the generalization of the culture of sports attributed to bringing the perception change about sports in Asian people, ② that it also contributed to spreading the Asia-origin sports to the world ③ that it established the infrastructure of sports in Asia through changing the game holding place among Asian countries, and ④ that it provided the good chances to exchange the national cultures among Asian countries. On the other hand the negative aspects may be mentioned ; ①that the loss of Asian traditional sports culture could be ascribed to the fact that the western sports has been the mainstream in Asian Games ② that the magnitude expansion strategy of the Games limited the number of Game hosting cities, so that only a few cities could hold the Game thus far, ③ that the original spirit of Asian Games has been impaired by making political use of Asian Games like the case of Olympic Games, and ④ that the deployment of diversity of world sports cultures into Asia was not enough Directions that Asian Games in 21st century is moving forward can be ; ① to study the Games operation centered on Asian traditional sports, ② to put efforts on magnitude optimization of the Game in size ③ seek the ways exclude the various non-sports ideologies in order for Asian Games to be the untained place of Asian harmony and advancement. To act Asian Games as a role to promote the Asian peace and goodwill among the Asian countries, the hosting country of the Games needs to establish the (hosting) policies and procedures toward of reconciling the different opinions among the member countries and enhancing the friendships, and to implement it. All participants to the international Games are requested to contribute to both the goodwill of Asian countries and world peace by the sportsmanship, the reciprocal cooperative competition.

전전자 교환기에서의 과부하제어에 관한 연구

林錫鳩,張殷永,金元厚 한국항공대학교 1991 論文集 Vol.29 No.-

TDX-10 및 EWSD 기종의 과부하 제어방식을 검토한 후 프로세서 점유율 측면에서 성능이 향상된 제어방식을 3가지로 분류하여 제안하며, 각각을 가정된 모델에 따라 시뮬레이션을 수행하여 성능평가를 행하였다. 그 결과 TDX-10L방식을 제외한 제안한 방식은 과부하 상태에서도 시스템 설계용량인 90%의 프로세서 점유율로 유지함을 확인하였다. The performance analysis of proposed three overload control methods is conducted to present the more optimal than methods using in conventional TDX-10 and EWSD by simulation with the assumed model. From simulation result, the two methods except TDX-10L are satisfied with 90% of the designed processor engineered capacity.

전산화단층상을 이용한 측두하악관절의 삼차원 재구성상의 비교연구

임숙영,고광준 大韓口腔顎顔面 放射線學會 1993 Imaging Science in Dentistry Vol.23 No.2

The purpose of this study was to clarify the spatial relationship of temporomandibular joint and to an aid in the diagnosis of temporomandibular disorder, For this study, three-dimensional images of normal temporomandibular joints were reconstructed by computer image analysis system and three-dimensional reconstructive program integrated in computed tomography. The obtained results were as follows: 1. Two-dimensional computed tomograms had the better resolution than three dimensional computed tomograms in the evaluation of bone structure and the disk of TMJ. 2. Direct sagittal computed tomograms and coronal computed tomograms had the better resolution in the evaluation of the disk of TMJ. 3. The positional relationship of the disk could be visualized, but the configuration of the disk could not be clearly visualized on three-dimensional reconstructive CT images. 4. Three-dimensional reconstructive CT images had the smoother margin than three-dimensional images reconstructed by computer image analysis system, but the images of the latter had the better perspective. 5. Three-dimensional reconstructive images had the better spatial relationship of the TMJ articulation, and the joint spaces were more clearly visualized on dissection images.

교육방송 TV 프로그램 시청자 요구분석

임재석,이영림 한국교육정보방송학회 2001 교육정보미디어연구 Vol.7 No.1

본 연구에서는 초·중·고등학생을 대상으로 텔레비전 시청형태와 기존 교육방송 프로그램에 대한 인지도 및 프로그램 내용에 대한 요구에 대해서 알아보았다. 이에 따라 수용자의 다양한 요구를 객관적으로 분석하여 현재 방송되는 프로그램에 대한 수용자의 의견을 향후 교육방송 프로그램 편성 및 제작에 대한 기초 자료를 제공하고자 하였다. 조사 내용은 학생들의 방송 프로그램 시청 습관, 교육 방송 프로그램 편성 요구, 교육 방송 프로그램 내용 요구, 교사들의 TV 활용 수업 의견 등 4가지 분야로 나누어 분석하였다. 분석 결과를 보면, 첫째, 초등학교 교과 프로그램은 자연과 영어 교과, 중학교 교과 프로그램은 사회와 영어 교과, 고등학교 교과 프로그램은 수리 탐구 영역(고 3 수학교과)과 외국어 영역(고3 영어 교과)을 증가해야 한다는 요구가 많았다. 둘째, 위성 TV 방송 출현으로 프로그램 방영 시간은 늘어났으나 시청 대상자의 방송 시청 시간이 증가한 것은 아니라는 점이다. 이유중의 하나는 프로그램을 흥미롭게 편성해 달라는 것이다. 다만 컴퓨터 정보 프로그램과 청소년 참여 프로그램을 중심으로는 시청율이 증가하고 있는 것으로 나타났다. 셋째, 시청자들이 교육방송 프로그램을 제대로 이해하고 활용할 수 있도록 적극적으로 홍보할 수 있는 방안이 강구되어야 할 것이다. The opinions of school students and teachers are very important in educational broadcasting program. They are the main users in educational broadcasting program. The purpose of this thesis is to suggest a new direction towards educational broadcasting programs, especially focussed on the need of school students and teachers. In order to conduct this research, the researcher analyzed literatures related to educational broadcasting system, program classification, the need , and the need analysis. To find the opinions of students and teachers, a survey was conducted to 6 elementary schools, 6 middle schools and 6 high schools in the Chung-Nam province, and the researcher especially collected and arranged the opinions of teachers who are working in the school related to this survey. The researcher was able to draw the following suggestions from the result of this study; 1. The programs should not be concentrated in educational programs, but should be broadened to the programs related to the things such as computer information and job. 2. The programs should be made with the format that students like, for example, animations or dramas. 3. A lot of marketing campaigns for educational broadcasting programs should be needed. 4. The study about the educational course programs should be continued to meet the needs of student audience.

증후성 Rathke열 낭종 : Transseptal transsphenoidal approach via columella flap

임동명,전세영,장석정 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

Rathke's cysts are sellar and suprasellar lesions that are found incidentally in about 13-22% of autopsy cases. Clinical symptoms of Rathke's cyst are usually the result of local mass effect. The most common symptom is headache, and other symptoms which arise are pituitary dysfunction, compression of the visual apparatus and the pituitary stalk. It is very important to distinguish Rathke's cyst from craniopharyngiomas(more common cystic tumor) because of the operative management. We reported a rare case of symptomatic Rathke's cleft cyst. This cyst was removed by transseptal transsphenoidal approach via columella flap. Postop result was satisfactory without serious complications.

공업화부재의 생산/운반/양중관리를 위한 정보가시화 시스템 개발에 관한 연구

임형철,송영석,김창덕,송성진 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

Recently, The construction field in the urban area is short of working space and securing processing place because it is surrounded by adjacent buildings and nearby roads and have difficulties in rising labor costs. The insufficient space causes problems of interference and conflicts in transporting materials and working at the site. Therefore, Construction Manager find many alternative method and select industrialized method. The objective of this paper is to develop and give a method of information visualization system for manufacturing, delivering and lifting these materials in construction project stakeholders, using tools visualizing informations. The tools supports to stakeholders so many informations in material manufacturing, delivering, lifting in construction site. That is, order information, manufacture information in factory, sending information, carrying information, unloading and lifting in Site, and so on. Case studies are performed to evaluate the feasibility and applicability of the proposed method.

K-WISC-Ⅲ를 이용한 ADHD 아동의 인지적 특성에 관한 연구

임목옥,오상우,백영석 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.2

Pulsed field gel electrophoresis(PFGE)를 이용한 Yersinia entirocolitica의 특성조사

임순영,윤석권 동덕여자대학교 생활과학연구소 2006 생활과학연구 Vol.11 No.-

Pulsed field gel electrophoresis(PFGE) was conducted compare the Not I digested genomic profile of one hundred Yersinia entirocolitica. This method was very efficient for subtyping pathogenic and non-pathogenic isolates of Yersinia entirocolitica. Generally, pulsotype was more closer to serotype than biotype. But pulsotype of 3/O:5 was more related to biotype than serotype. For epidemiological purpose, the comparison of relationship among biotype. serotype, RAPD(random amplitication of polymorphic DNA) and pulsotype of PFGE should be studied as powerful tools.