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      • KCI등재

        Synthesis and application of 8-hydroxyquinoline modified magnetic mesoporous carbon for adsorption of multivariate metal ions from aqueous solutions

        Wenlu Guo,Xiangguo Meng,Yan Liu,Liang Ni,Zhaoyong Hu,Rui Chen,Minjia Meng,Yun Wang,Juan Han,Min Luo 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.21 No.1

        The new 8-hydroxyquinoline (8-HQ) modified magnetic mesoporous carbon (8-HQ-Ni-CMK-3) wasprepared and applied for adsorption of multivariate metal ions from aqueous solution. The preparedadsorbent was characterized by Fourier transform infrared, X-ray diffraction, scanning electronmicroscopy, transmission electron microscope, nitrogen adsorption-desorption isotherm, elementalanalysis, and vibrating sample magnetometer. The static adsorption behaviors toward multivariatemetal ions on graphite, the modified graphite by 8-HQ, magnetic mesoporous carbon, and 8-HQ-Ni-CMK-3 were compared, which showed that 8-HQ-Ni-CMK-3 had excellent adsorption capacity. Theremoval of multivariate metal ions using 8-HQ-Ni-CMK-3 by fixed-bed column was further investigated.

      • KCI등재

        Generation of Hydrogen Peroxide by Single-Atom Clusters Pd Anchored on t-BaTiO3 for Piezoelectric Degradation of Tetracycline

        Xin Ni,Yuan Liang,Quanzi Pan,Hengjie Guo,Kai Chen,Bo Zhang,Shaocong Ni,Bin Sheng,Zeda Meng,Shouqing Liu,오원춘 한국재료학회 2023 한국재료학회지 Vol.33 No.11

        Single-atom Pd clusters anchored on t-BaTiO3 material was synthesized using hydrothermal and ultrasonic methods for the effective piezoelectric catalytic degradation of pollutants using vibration energy. XRD patterns of BaTiO3 loaded with monoatomic Pd were obtained before and after calcining, and showed typical cubic-phase BTO. TEM and HAADF-STEM images indicated single-atom Pd clusters were successfully introduced into the BaTiO3. The piezoelectric current density of the prepared Pd-BaTiO3 binary composite was significantly higher than that of the pristine BaTiO3. Under mechanical vibration, the nanomaterial exhibited a tetracycline decomposition rate of ~95 % within 7 h, which is much higher than the degradation rate of 56.7 % observed with pure BaTiO3. Many of the piezo-induced electrons escaped to the Pd-doped BaTiO3 interface because of Pd’s excellent conductivity. Single-atom Pd clusters help promote the separation of the piezo-induced electrons, thereby achieving synergistic catalysis. This work demonstrates the feasibility of combining ultrasonic technology with the piezoelectric effect and provides a promising strategy for the development of ultrasonic and piezoelectric materials.

      • KCI등재

        Mode identifiability of a cable-stayed bridge based on a Bayesian method

        Feng-Liang Zhang,Yi-Qing Ni,Yan-Chun Ni 국제구조공학회 2016 Smart Structures and Systems, An International Jou Vol.17 No.3

        Modal identification based on ambient vibration data has attracted extensive attention in the past few decades. Since the excitation for ambient vibration tests is mainly from the environmental effects such as wind and traffic loading and no artificial excitation is applied, the signal to noise (s/n) ratio of the data acquired plays an important role in mode identifiability. Under ambient vibration conditions, certain modes may not be identifiable due to a low s/n ratio. This paper presents a study on the mode identifiability of an instrumented cable-stayed bridge with the use of acceleration response data measured by a long-term structural health monitoring system. A recently developed fast Bayesian FFT method is utilized to perform output-only modal identification. In addition to identifying the most probable values (MPVs) of modal parameters, the associated posterior uncertainties can be obtained by this method. Likewise, the power spectral density of modal force can be identified, and thus it is possible to obtain the modal s/n ratio. This provides an efficient way to investigate the mode identifiability. Three groups of data are utilized in this study: the first one is 10 data sets including six collected under normal wind conditions and four collected during typhoons; the second one is three data sets with wind speeds of about 7.5 m/s; and the third one is some blind data. The first two groups of data are used to perform ambient modal identification and help to estimate a critical value of the s/n ratio above which the deficient mode is identifiable, while the third group of data is used to perform verification. A couple of fundamental modes are identified, including the ones in the vertical and transverse directions respectively and coupled in both directions. The uncertainty and s/n ratio of the deficient mode are investigated and discussed. A critical value of the modal s/n ratio is suggested to evaluate the mode identifiability of the deficient mode. The work presented in this paper could provide a base for the vibration-based condition assessment in future.

      • KCI등재

        Complex roles of the stroma in the intrinsic resistance to gemcitabine in pancreatic cancer: where we are and where we are going

        Chen Liang,Si Shi,Qingcai Meng,Dingkong Liang,Shunrong Ji,Bo Zhang,Yi Qin,Jin Xu,Quanxing Ni,Xianjun Yu 생화학분자생물학회 2017 Experimental and molecular medicine Vol.49 No.-

        Pancreatic ductal adenocarcinoma (PDAC) is among the most devastating human malignancies. The poor clinical outcome in PDAC is partly attributed to a growth-permissive tumor microenvironment. In the PDAC microenvironment, the stroma is characterized by the development of extensive fibrosis, with stromal components outnumbering pancreatic cancer cells. Each of the components within the stroma has a distinct role in conferring chemoresistance to PDAC, and intrinsic chemoresistance has further worsened this pessimistic prognosis. The nucleoside analog gemcitabine (GEM) is usually the recommended first-line chemotherapeutic agent for PDAC patients and is given alone or in combination with other agents. The mechanisms of intrinsic resistance to GEM are an active area of ongoing research. This review highlights the important role the complex structure of stroma in PDAC plays in the intrinsic resistance to GEM and discusses whether antistroma therapy improves the efficacy of GEM. The addition of antistroma therapy combined with GEM is expected to be a novel therapeutic strategy with significant survival benefits for PDAC patients.

      • KCI등재

        Operational modal analysis of Canton Tower by a fast frequency domain Bayesian method

        Feng-Liang Zhang,Yan-Chun Ni,Yan-Chun Ni,You-Wu Wang 국제구조공학회 2016 Smart Structures and Systems, An International Jou Vol.17 No.2

        The Canton Tower is a high-rise slender structure with a height of 610 m. A structural health monitoring system has been instrumented on the structure, by which data is continuously monitored. This paper presents an investigation on the identified modal properties of the Canton Tower using ambient vibration data collected during a whole day (24 hours). A recently developed Fast Bayesian FFT method is utilized for operational modal analysis on the basis of the measured acceleration data. The approach views modal identification as an inference problem where probability is used as a measure for the relative plausibility of outcomes given a model of the structure and measured data. Focusing on the first several modes, the modal properties of this supertall slender structure are identified on non-overlapping time windows during the whole day under normal wind speed. With the identified modal parameters and the associated posterior uncertainty, the distribution of the modal parameters in the future is predicted and assessed. By defining the modal root-mean-square value in terms of the power spectral density of modal force identified, the identified natural frequencies and damping ratios versus the vibration amplitude are investigated with the associated posterior uncertainty considered. Meanwhile, the correlations between modal parameters and temperature, modal parameters and wind speed are studied. For comparison purpose, the frequency domain decomposition (FDD) method is also utilized to identify the modal parameters. The identified results obtained by the Bayesian method, the FDD method and a finite element model are compared and discussed.

      • KCI등재

        Associations of hypoxia inducible factor-1a gene polymorphisms with susceptibility to digestive tract cancers: a case–control study and meta-analysis

        Zhi-Hai Ni,Xian-Jun Liang,Jing-Gang Mo,Yi Zhang,Jian-Hua Liang,Yu-Sha Yang,Yong Zhou,Zhao-Hua Li,Jian-Liang Zhang,Yin-Lu Ding,Peng Zhang,Jin-Qing Wang 한국유전학회 2015 Genes & Genomics Vol.37 No.11

        We aim to investigate the correlations of hypoxia inducible factor-1a (HIF-1a) C1772T (rs11549465) and G1790A (rs11549467) gene polymorphisms with digestive tract cancers. A sum of 267 digestive tract cancers patients were hospitalized in Taizhou Central Hospital of Zhejiang Province as case group between December 2012 and December 2014. Additionally, 275 healthy people who had a physical examination in our hospital at the same time were selected as control group. Polymerase chain reaction-restriction fragment length polymorphism was utilized for detecting allele and genotype frequency of different locus in case and control group. Meta-analysis was performed using Comprehensive Metaanalysis 2.0 (Biostat Inc., Englewood, New Jersey, USA). Our result showed statistical significance only exists in family history of cancer between case and control group (P\0.05). Both C1772T (rs11549465) and G1790A (rs11549467) polymorphisms showed positive correlations with an increasing risk of digestive tract cancers. The frequencies of TT genotype of C1772T (rs11549465) and GA, AA genotypes of G1790A (rs11549467) polymorphisms in case group were evidently higher compared with the controls (all P\0.05). Besides, the comparison of allele and dominant models of HIF-1a C1772T (rs11549465) and G1790A (rs11549467) between two groups showed a significant difference (all P\0.05). Meta-analysis results further confirmed that the onset risk of digestive tract cancers may be improved under allele and dominant models of HIF-1a C1772T (rs11549465) and G1790A (rs11549467) (all P\0.05). Single nucleotide polymorphisms of HIF-1a C1772T (rs11549465) and G1790A (rs11549467) may play a role in development of digestive tract cancers.

      • KCI등재

        Genome-wide identification and expression analysis of the aquaporin gene family reveals the role in the salinity adaptability in Nile tilapia (Oreochromis niloticus)

        Ni Ping,Zhao Xiang,Liang Yujun 한국유전학회 2022 Genes & Genomics Vol.44 No.12

        Background: Nile tilapia (Oreochromis niloticus), an important economic freshwater fish being cultured globally, is highly adaptable to a wide range of salinities. However, little information is currently available on the mechanism of salinity adaptation. Objective: For a better understanding of this intriguing adaptability, we identified and analyzed aquaporins (AQPs), which are channel proteins with a basic function of intracellular and intercellular transportation for water and certain solutes. Methods: In the present study, we performed genome-wide identification and comprehensive analysis of the duplicated AQP genes in Nile tilapia by bioinformatics methods. Tissue-specific analyses were then combined with transcriptome data under different salinity treatments. Results: It was revealed that Nile tilapia has a total of twenty-eight AQPs, which are distributed unevenly on twelve chromosomes and belong to four subfamilies according to phylogenetic analysis. These AQPs share conserved AQP characteristic structural domains and motifs, although they differ in molecular weight from 23 to 36 kDa and contain distinct sequences. GO analysis revealed that most AQPs have transporter protein activity and are involved in biological processes such as substance transport, stress response, development and metabolism. KEGG enrichment analysis showed that AQPs were significantly enriched in two pathways, anti-diuretic hormone-regulated reabsorption and bile secretion. Conclusion: These results suggested that Nile tilapia has a highly developed, albeit complex, osmotic pressure regulation system, which provided a molecular basis for exploring how these AQP members coordinate to help Nile tilapia cope with different salinities.

      • Serum IL-33 as a Diagnostic and Prognostic Marker in Non-small Cell Lung Cancer

        Hu, Liang-An,Fu, Yu,Zhang, Dan-Ni,Zhang, Jie Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4

        Background: Interleukin-33 (IL-33) has recently been implicated in tumor immunity. The aim of this study was to explore the clinical role of serum IL-33 in patients with non-small-cell lung cancer (NSCLC). Methods: Sera collected from 250 healthy volunteers (HV), 256 patients with benign lung diseases (BLD) and 262 NSCLC cases were subjected to IL-33 ELISA and relationships between serum IL-33 and clinical characteristics were evaluated. Results: Circulating IL-33 levels were higher in the NSCLC group in comparison with the HV and BLD groups (p<0.001). Using a cut-off level 68 pg/ml (95% specificity in the HV group), IL-33 showed a good diagnostic performance for NSCLC. Multivariate survival analysis indicated that serum IL-33 was an independent prognostic factor in the entire NSCLC group [hazards ratio (HR) = 0.64 for low versus high IL-33 levels, 95% confidence interval (CI) 0.50-0.82; p<0.001] and in 165 selected patients with locally advanced or metastatic disease receiving chemoradiotherapy or chemotherapy (HR 0.70, 95% CI 0.52-0.94; p=0.013). Conclusions: IL-33 is a promising potential diagnostic and prognostic marker in NSCLC, independent of the therapeutic intervention.

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