Serial values for hematologic and biochemical analysis after myocardial infarction in rats

Lee, Mi-Jin,Tae, Hyun-Jin,Li, Ying-Hua,Yu, Do-Hyeon,Han, In-Ae,Lee, Seok-Won,Ahn, Dong-Choon,Kim, In-Shik,Park, Jin-Ho The Korean Society of Veterinary Service 2008 韓國家畜衛生學會誌 Vol.31 No.2

To diagnose acute myocardial infarction (MI), many cardiac markers have been used in hematologic and biochemical analysis, and many studies have been published for hematologic and biochemical analysis associated with human acute MI. However, after occurrence of acute MI, the serial investigation for values in hematologic and biochemical analysis including chronic MI has rarely been performed. To observe the change of the serial values in hematologic and biochemical analysis, we induced artificial MI. The left main descending artery (LMDA) of the left coronary artery was ligated during the progression (day 1, 3, 5, 7, 14 and 30) of MI. Total 66 Sprague-Dawley rats were divided into the sham group (n=24, thoracotomy without LMDA ligation) and the experimental (MI) group (n=42, with LMDA ligation). And all individual in each group was sacrified at day 1, 3, 5, 7, 14 and 30 for the hematologic and biochemical analysis. In comparison of hematologic analysis between the sham and MI groups, the mean values of red blood cell (RBCs), hemoglobin and hematocrit (HCT) showed a steady increase. In biochemical analysis, the mean values of glucose, cholesterol, total creatine kinase (CK) and isoenzyme MB, and lactate dehydrogenase (LDH) were increased in all MI groups compared with the sham groups. The results of this study suggest that early hematologic and biochemical mean values occurred after acute MI are similar to those of human acute MI. In conclusion, we could observe the alterations and serial values in hematologic and biochemical analysis to the extent of chronic status after acute MI.

Serial values for hematologic and biochemical analysis after myocardial infarction in rats

( Mi Jin Lee ),( Hyun Jin Tae ),( Ying Hua Li ),( Do Hyeon Yu ),( In Ae Han ),( Seok Won Lee ),( Dong Choon Ahn ),( In Shik Kim ),( Jin Ho Park ) 한국가축위생학회 2008 韓國家畜衛生學會誌 Vol.31 No.2

To diagnose acute myocardial infarction(MI), many cardiac markers have been used in hematologic and biochemical analysis, and many studies have been published for hema-tologic and biochemical analysis associated with human acute MI. However, after occurrence of acute MI, the serial investigation for values in hematologic and bioche-mical analysis including chronic MI has rarely been performed. To observe the change of the serial values in hematologic and biochemical analysis, we induced artificial MI. The left main descending artery(LMDA) of the left coronary artery was ligated during the progression(day 1, 3, 5, 7, 14 and 30) of MI. Total 66 Sprague-Dawley rats were divided into the sham group(n=24, thoracotomy without LMDA ligation) and the experimental(MI) group(n=42, with LMDA ligation). And all individual in each group was sacrified at day 1, 3, 5, 7, 14 and 30 for the hematologic and biochemical analysis. In comparison of hematologic analysis between the sham and MI groups, the mean values of red blood cell(RBCs), hemoglobin and hematocrit(HCT) showed a steady increase. In biochemical analysis, the mean values of glucose, choles-terol, total creatine kinase(CK) and isoenzyme MB, and lactate dehydrogenase(LDH) were increased in all MI groups compared with the sham groups. The results of this study suggest that early hematologic and biochemical mean values occurred after acute MI are similar to those of human acute MI. In conclusion, we could observe the alterations and serial values in hematologic and biochemical analysis to the extent of chronic status after acute MI.

항암화학요법 관련 오심과 구토 완화를 위한 비약물요법에 관한 연구동향

소향숙,최자윤,조인숙,김영재,김지영,김애숙,김옥미,김춘심,김현오,설영애,안정옥,이애리,이영자 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: Purposes of this study were to understand the current trends on complementary therapy in relieving chemotherapy-induced nausea and vomiting and to suggest the future research direction. Method: Subjects were selected on CINAHL, MEDLINE, Korean Academy Data Base from 1980 to 2001 which used nausea, vomiting, chemotherapy and complementary therapy as key words in experimental studies. Eight korean articles and twenty-one international articles were analyzed in terms of general characteristics, research methods, and types of complementary therapy. Data were analyzed by using descriptive statistical methods. Result: Since 2000, researchers have more actively used complementary therapy. In subject characteristics, mean age was 35.5 years old, 45% of the researchers were performed with high level of incidence of chemotherapy induced vomiting, 14% of them set limit of consecutive cycle during research, and 65% of them did not comment the selecting criteria of sample. About 60% of them were designed post-test only control group: 35% used INV by Rhodes, 31% used Likert scale, and 24% used VAS for dependent variable. Muscle relaxation therapy was mostly applied for relief of nausea and vomiting. Conclusion: Further studies will be needed to control extrinsic variables affecting nausea and vomiting in research design and to accumulate evidence with studies applying various complementary therapies.

암 병동 간호사의 통증관리에 대한 지식과 태도

공성화,방찌야,서민숙,현신숙,김희정,이미애1,이미애2,유현희,허재경,김은애,박경숙 성인간호학회 2004 성인간호학회지 Vol.16 No.1

Purpose: The purpose of this study is to evaluate the knowledge and attitudes of oncology ward nurses toward cancer pain management and to find ways to improve the educational program for nurses. Method: A total of 209 nurses working at the oncology ward of three hospitals in Seoul and a Gyenggi Province. The survey instrument used was the 32-item scale for evaluating nurses knowledge and attitudes originally developed by McCaffery and Ferrell'(1990). that was by Kim'(1997). Result: In terms of the nurses knowledge of pain management. the result showed that the nurses scored an average of 67.8 out of 100 for phamacokinetics of opioids. 84.8 for classification of analgesics, 60.1 for pain assessment, and 70.7 for drug administration. 18.2% of the nurses hesitate to inject the narcotic agent because of concerns regarding the drug's potential side effects. there was significant difference in the knowledge of pain management according to the general characteristics of pain in terms of the nurses age(p=.001), position (p=.016). years of experiences(p=.002), experience of cancer pain education(p= .001). Conclusion: The also showed that nurses working at cancer ward lack knowledge. It is important to provide intensive education to nurses about cancer pain management.

中學校 漢文科 情意的 領域의 學習效果에 관한 硏究

李美愛 한국한문교육학회 2003 한문교육논집 Vol.20 No.-

본 硏究의 目的은 학생들에게 健全한 價値觀과 바람직한 人性을 함양해 주기 위해서 정의적 영역이 부가된 한문과 수업을 하고, 그리고 이 수업으로부터 정의적 영역이 어느 정도 길러지는지를 實證的으로 분석하여 情意的 領域의 學習效果를 규명하는데 있다. 이를 위하여 假說 說定과 함께 중학교 한문과 교육과정에서의 정의적 영역과 학습목표에 의거한 정의적 영역의 學習要素를 抽出하고 이를 교육현장에서 학생들에게 적용하여 정의적 영역이 부가된 한문과 수업으로부터 학교에서 배운 것을 實生活에 직접 실천 가능한 生活態度 領域, 학업과 관련된 學習態度 領域, 어떤 목표를 달성하는데 꼭 필요한 자기 자신을 가치 있는 존재라고 믿고 자신을 잘 통제할 수 있는 自我尊重感 領域, 학생의 사회성을 탐구하기 위한 交友關係 즉 인간관계 영역으로 나누어 그 全體效果와 各 領域別 要因의 效果를 살펴보았다. 연구 결과 學業成就度에 미치는 效果에서는 정의적 영역을 부가한 한문과 수업을 받은 實驗集團이 인지적인 전통적 한문과 수업을 받은 統制集團보다 學業成就度 事後檢査 평균점수가 4.3286점 더 높게 나타났다. 정의적 영역을 부가한 한문과 수업과 인지적인 전통적 한문과 수업이 情意的 領域(生活態度, 學習態度, 自我尊重感 및 交友關係) 全體에 미치는 效果를 분석한 결과 통제집단은 사전에 비해 사후에 평균이 1.8889점 높아졌으나 실험집단은 사전에 비해 사후에 평균이 8.0526점 상승되었다. 따라서 실험집단 중학생들이 情意的 領域 全體에서 더욱 肯定的인 效果가 있음이 나타났으며 그리고 생활태도, 학습태도, 자아존중감 및 교우관계에서도 실험집단 학생들이 더욱 긍정적인 효과가 있다는 것이 분석되었으며, 各 要因別 分析에서도 實驗集團 學生들이 더욱 肯定的인 效果가 있는 것으로 나타났다. The purpose of this study was to examine the learning effects on the academic achievement and affective domain (practical attitudes for living, learning attitudes, self-esteem and schoolmate relations) in Korean classical Chinese education of the Junior high school. To achieve the purpose of study, the following problems were formulated. First, Which is more effective in academic achievement on the traditional teaching method or the affective teaching method which emphasized the affective domain along with the traditional teaching method in Korean classical Chinese education of the Junior high school? Second, Which is more effective in the affective domain on the traditional teaching method or the affective teaching method which emphasized the affective domains along with the traditional teaching method in Korean classical Chinese education of the Junior high school? And, for attaining the purpose of study, the classes were divided into two groups, experimental group and control group. The traditional teaching method was applied to the control group, but the affective teaching method which emphasized the affective domain along with the traditional teaching method was applied to the experimental group. The questionnaire by Likert measurement as a test method was used. The respondence from the questionnaire were processed in SPSS/WIN 10.0. The results of this study were as follows: 1. Effects of Academic Achievement There was no statistical significant difference in the academic achievement (p=0.506>0.05) between the experimental and control group, but the average credit of the experimental group was higher (4.3286 credits) than control group. Therefore, the experimental group was more effective than the control group in the academic achievements of students. 2. Effects of Affective Domain There was statistical significance difference in the whole affective domain (p=0.001<0.05) between the two groups. And the average credit of the experimental group was higher (6.1637 credits) than the control group. Therefore, the experimental group was more effective than the control group in the whole affective domain of students. The results of each factor in affective domain as follows: 1) effects of practical attitudes for living There was statistical significant difference in the whole practical attitudes for living (p=0.003<0.05) between the two groups. And the average credit of experimental group was higher (2.0000 credits) than the control group. Therefore, the experimental group was more effective than the control group in the whole practical attitudes of students for living (personal living, home living, social and national living). 2) effects of learning attitudes There was no statistical significance difference in the whole learning attitudes (p=0.566>0.05) between the two groups, but the average credit of the experimental group was higher (0.3948 credits) than the control group. Therefore, the experimental group was more effective than the control group in the whole learning attitudes of students. 3) effects of self-esteem There was no statistical significant difference in the self-esteem (p=0.312>0.05) between the two group, but the average credit of the experimental group was higher (0.9327 credits) than the control group. Therefore, the experimental group was more effective than the control group in the whole self-esteem of students. 4) effects of schoolmate relation There was statistical significant difference in the whole schoolmate relation (p=0.000<0.05) between the two group. And the average credit of the experimental group was higher (2.7280 credits) than the control group. Therefore, the experimental group was more effective than the control group in the whole schoolmate relation of students. On the basis of the above results, we found that the affective teaching method was more effective than traditional teaching method for increasing the student's academic achievement and growing the student's affective domain such as practical attetudes for living, learning attitudes, self-esteem and schoolmate relation. Thus this study suggests that the affective teaching method in Korean classical Chinese education should be promoted as a means of the formating student's sound view of value and warm human nature from elementary school.

탈지대두박을 활용한 콩치즈와 스폰지 케익의 품질특성

이숙영,박미정,최애진 중앙대학교 생활과학연구소 2001 생활과학논집 Vol.14 No.-

The effects of the different mixing ratios(10:0, 7:3, or 5:5) of Jinpum soybean milk to defatted soybean meal milk and the different enzyme treatments with α -chymotrypsin or trypsin on the yields, physicochemical and textural properties, and sensory characteristics of soybean cheeses were studied. The effects of the different replacement amounts(15, 30, or 45%) of defatted soybean meal on the physicochemical and sensory characteristics of sponge cake were also studied. In the results of yield, pH, lightness, hardness, mouthfeel and overall quality of sensory characteristics, the mixing ratio of 7:3 and the trypsin treatment were recommended for better manufacturing of high-quality soybean cheese. In the results of moisture contents, specific gravity, and overall quality of sensory characteristics, there were no significant differences between control and the sample of 15% replacement with untreated defatted soybean meal, and also between control and that of 30% replacement with trypsin-treated. The trypsin treatment of defatted soybean meal resulted in similar texture to control, the decrease in beany flavor, softer mouthfeel, and better moistness.

거대 난소 종양의 염전 1예

김미영,이해혁,유애리,박정희,이임순,정수호,고은석,레앙소팥,배동한,김태희,이권해 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

..

기능평가를 통한 장애유아의 행동지원 실험연구 분석 : 1997~2006년 사이의 연구를 중심으로

이미애,한성희,이규옥 국립특수교육원 2007 특수교육연구 Vol.14 No.2

이 연구는 유아를 대상으로 기능평가를 통한 행동지원을 제공한 실험연구를 분석하여 현재의 전반적인 특징과 경향을 분석하고 문제행동 기능의 결과가 중재와 어떻게 연결되는지 살펴봄으로써 문제행동 중재를 위한 향후의 방향을 모색하고자 하였다. 이 연구의 분석 대상 논문은 주로 중다기초선 설계법을 사용하며 중재는 일반교실이나 가정 등의 자연스러운 환경에서 교사나 부모 등의 자연스러운 중재자에 의해서 이루어지고 있었으며 목표행동은 대상유아의 바람직한 행동보다는 부정적인 행동이 많았으며 중재자의 행동을 목표행동으로 본 연구도 5-6편이 있었다. 연구의 질적 수준에 대한 변인들 중 관찰자간 신뢰도를 제외하고는 중재충실도, 사회적 타당도, 유지, 일반화 등에 대한 파악이 부족한 것으로 나타났다. 기능평가는 주로 일반학급과 가정 등의 자연스러운 환경에서의 부모나 일반교사를 대상으로 한 인터뷰와 연구자나 가족, 교사 등에 의한 관칠 방법, 연구자에 의한 기능분석 방법이 많이 이용되었다. 기능평가 방법으로는 직접관찰과 인터뷰가 가장 많이 이용되었으며 평균 2~3가지 방법을 사용하고 있었으며 문제행동의 기능은 관심끌기가 가장 높았고 획득과 회피, 감각적 자극 순으로 나타났다. 행동의 기능에 따른 중재전략을 살펴보면 획득기능과 회피 기능을 가진 경우에는 선행사건 예방전략과 후속반응전략이 가장 많이 사용되었고 관심의 기능을 가진 경우에는 후속반응전략이, 감각적 자극을 목적으로 한 문제행동 중재에는 문제행동을 차단하는 전략이 사용되고 있었다. The purpose of this study was to analyze experimental studies that intervened young children's challenging behavior using functional assessment and to provide information and suggestions on future research. To accomplish this purpose, the elements of experimental study, the quality features of study(interobserver agreement, fidelity of intervention, social validity, maintenance and generalization of effect) and methods of functional assessment and intervention strategies were analyzed. The major findings of this study was followed. First, most of the analyzed articles used multi-baseline design, and the interventions were implemented were natural settings like classroom and home, and the interventionists were natural people like teachers and parents. Target behaviors were focused on problematic behaviors of subjects than desirable behaviors. Second, among the 5 quality features of study I chose, fidelity of intervention, social validity, maintenance and generalization of effect were identified poorly except interobserver agreement. Third, functional assessment was implemented by natural people like teachers and family members, and at the natural settings like classrooms and home routine. Interview to teachers and family members and direct observation by researchers, teachers and family members were used. The most common functional assessment methods were direct observation and interview. And 2 or 3 methods were used one study. The order of the function of problematic behavior was attention, obtain tangible, escape, and sensory stimulation. As an interventions strategies, antecedents events, alternative skills and consequent responding were applied comparatively the same rate. Based on this results, some recommendations are suggested.

촉각훈련 프로그램이 발달지체유아의 상동행동에 미치는 효과

이미경,김성애 한국정신지체아교육학회 2003 지적장애연구 Vol.5 No.-

본 논문은 촉각프로그램이 발달지체 유아의 동작관련 및 언어관련 상동행동에 미치는 영향과 그 두 차원의 상동행동의 발생빈도 관계를 알아보는 것이다. 연구의 대상은 자폐 성향을 띤 발달지체 유아 2명이며, 연구방법은 단일 대상연구 AB 설계가 적용되었다. 연구 결과는 다음과 같다: 첫째, 촉각훈련 프로그램은 발달지체 유아의 동작관련 상동행동 발생빈도 감소에 긍정적인 효과가 있다. 둘째, 촉각훈련 프로그램은 발달지체 유아의 언어관련 상동행동 발생빈도 감소에 긍정적인 효과가 있다. 셋째, 촉각훈련 프로그램은 상동행동을 동반하는 발달지체유아의 언어 관련 상동행동보다 동작 관련 상동행동의 발생빈도 감소에 더 긍정적인 효과가 나타난다. The purpose of this study is to investigate the effect of training program for tactile sensation on the change of retarded children's stereotype behaviors. The subjects were two five-year-old boy and girl who were autistic retarded children. The training program for tactile sensation was applied among sense integration activities by learning materials of early treatment for autistic children (Kang Ui Hong, Bo In chung and Sang Bok Lee, 1998). As a method, single subject AB design was executed in the periods of foundation, arbitration and maintenance for 38 times and visual analysis was used by observing and recording the frequency of stereotype behaviors. The summary of the results of the study is as follows: First, the training program for tactile sensation for retarded children had an effect on the decrease of frequency of stereotype behaviors regarding behaviors. Second, the training program for tactile sensation for retarded children had an effect on the decrease of frequency of stereotype behaviors regarding language. Third, the training program for tactile sensation for autistic retarded children had a greater effect on the decrease of frequency of stereotype behaviors regarding behaviors than stereotype behaviors regarding language. The suggestions as results of the study are as follows: First, age distribution of the subjects and place in this study was confined to generalization. Therefore, further study of verification on the effect of various age groups and places is needed. Second, further study of the level of stress that stereotype behaviors of retarded children has on the families and the level of stress after the arbitration of training program for tactile sensation is needed actively.

아동이 지각한 사회적 지지와 자아존중감과의 관계

이미애,정회욱 木浦大學校 敎育硏究所 2004 교육연구 Vol.16/17 No.-

본 연구는 초등학교 아동들이 건강한 생활에 적응하는데 긍정적인 영향을 주는 자아존중감이 주변의 의미 있는 타인 즉, 아버지, 어머니, 담임선생님, 학급친구들로부터 받고 있다고 지각하는 사회적 지지와 어떤 상관이 있는가 알아보고자 하였다. 연구 결과를 요약하면 다음과 같다. 남자보다 여자 어린이가 친구의 지지를 많이 받고 있다고 지각하고 있었다. 아이들은 형제수가 적을수록 어머니의 지지를 많이 받고 있다고 지각하며, 어머니의 학력이 높을수록 아버지의 지지를 더 많이 받고 있다고 지각하였다. 아이들은 어머니의 학력이 높을수록 일반적 자아존중감이 높았고, 형제수가 적을수록 높은 가정적 자아존중감을 보였다. 아이들의 자아존중감은 사회적 지지의 하위 영역 중 정서적 지지와 가장 높은 상관을 보였으며, 사회적지지 제공자 중에서는 어머니의 지지와 가장 상관이 있었다. 또한, 아동의 학교와 관련된 자아존중감은 교사의 사회적지지 지각과 가장 높은 상관이 있었다. 또 아동의 사회적 자아존중감은 친구로부터의 지지 지각과 가장 상관이 높았다. 회귀분석의 결과 아이들의 자아존중감에 가장 영향을 많이 미치는 지지 제공자 변인은 어머니의 지지와 학급친구의 지지로 나타났다. The purpose of this is to investigate the correlation between children's social support provided by parents, teachers, classmates and other close people and children's self-esteem that have a meaninful effect on their wholesome life. In this research, 331 students of 6th grade students in Haenam, Jeon-Nam Province were selected. Coopersmith's self-esteem inventory revised by Whang Chang-gu(1988) was used to measure children's self-esteem and Park Ji-won(1985)'s social-support Inventory revised by Whang Yun-gyeong(1955) to measure children's social support. The relationship between social support and children's self-esteem were analyzed by Pearson correlation analysis and multiple regression analysis. The results of the study were as follows; First, social support and children's personal variables(sex, the number of brothers, the number of family, parents' scholarship, etc) didn't have any correlation. Second, female students perceived more social support than male students did from friends. And students perceived more social support when they had fewer brothers and when their mothers had more school education. Third, children's self-esteem was high when their mothers had more school education and when they had fewer brothers. Fourth, the social support perceived by children and their self-esteem was correlated significantly. Particularly their self- esteem showed high correlation with emotional support perceived. That is, the more emotional support they perceived, the higher their self-esteem was. Fifth, children's self-esteem was influenced more by their mother's support than by any other kind of social support. Also their self-esteem in their school life had high correlation with the teachers' social support on themselves. Finally, mother's and friends' support had the highest influencing power on children's self-esteem.