사후분해 시체에 대한 법의학적 접근

최영식,이상용,김유훈,조갑래,이봉우,양경무,정낙은,서중석,이한영,이원태,강현욱 大韓法醫學會 2000 대한법의학회지 Vol.24 No.2

Disposal of a homicide victim by dismemberment is rare, but individual cases are on record in most major medicolegal departments. Recognition of postmortem mutilation may be of importance in the interpretation of certain murders committed by sexual perverts and other mentally deranged individuals and sometimes performed for the sole reason of easier disposal of the body. Postmortem dismemberment is usually readily recognizable as such; The edges of the injuries are dry and lack evidence of bleeding. The joints may be disarticulated without fracture, or the use of an axe or saw may be evident from examination of bones. Parallel horizontal or oblique furrows in the bone surface are caused by skipping of the saw prior to establishing depth. Such patterns on the bone may assist in identifying the particular saw involved. So we report 25 dismembered corpses that autopsied in National Institute of Scientific Investigation. This paper can help in attempting to establish not only the first criminal investigation steps but also the medicolegal approach methods in unidentified and dismembered deaths.

건축에서의 미니멀리즘 논의를 위한 개념적 고찰 : 미학적 과정 검토를 통한 미니멀리즘 논의의 조건 모색 Search for Conditions of Minimalism Discussions through Review on Aesthetic Process

이중용,정성원 대한건축학회 2004 대한건축학회논문집 Vol.20 No.11

Due to multidisciplinary characteristic of the architectural field, it has developed into complex interdisciplinary field. Therefore architecture field has grown and established its major trends dependent upon other related field of study. With this perspective in mind, esthetics on architecture has to be treated in similar manner. In contemporary architecture, some architecture and architects have defined the terminology "Minimalism" or "Minimalist" without any theoretical principle where by unable to distinguish between "simple" and "minimal", Presently, the term "minimal" became a trend word. In order to confront misconception of the idea of minimalism, some people defend the lack of definition as reflection of this complex society. However others feel that it is still necessary to suggest tangible criteria on the topic of minimalism. In this paper, it will establish a solid groundwork for a discussion on minimalism in architecture. The initial approach will deal with esthetics, which is the center of argument. By reviewing theoretical background of the related modern art, the paper discusses about the relationship between minimalism and esthetics. Subsequently, the discussion about the criterions necessary to define minimalism is provided. This paper only suggests a methodology of analyzing a trend in architecture. The condition to define minimalism in architecture, which is a result of the reviewing process on esthetics, can be concluded as "self-definition" and "transferring to the original experience type" of the architecture.

신경섬유종증(렉클링하우젠병)에 의한 급사 1예 보고

이봉우,서중석,권태정,이원태 大韓法醫學會 2000 대한법의학회지 Vol.24 No.1

Neurofibromatosis type1(von Recklinghausen's disease) is characterized by multiple skin tumors and abnormal cutaneous pigmentation(cafe au lait spots). Unlikely the solitary neurofibroma, those encountered in von Recklinghausen's disease may cause significant morbidity. The vasculopathy, although poorly recognized manifestation of von Recklinghausen's neurofibromatosisis a major case of fatal cases. One of its most dramatic presentation is the spontaneous hemothorax. We report a case of Von Recklinghausen's disease with multiple neurofibromatosis accompanying intrathoracic hemorrhage due to vascular rupture, which is the first legal autopsy case in Korea.

무증상 대퇴골두 무혈성 괴사의 증상발현

원중희,김용민,최의성,이호승,서중배,배병권 대한고관절학회 2001 Hip and Pelvis Vol.13 No.1

HBsAg양성 원발성간암에 있어서 HBV-DNA표지자의 PCR성적

이원길,김재식,김정철,서장수,강은자,이중원,김기연,송경은,양정선 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.2

목적 : HBV-DNA를 정성적 그리고 정량적으로 검출함으로써 강한 전염성과 높은 유병율로 인해 사회적으로 문제가 되는 B형 간염과 원발성간암의 연관성을 알아보고자 하였다. 대상 및 방법 : B형 간염 표면항원(HBsAg)이 양성을 보이는 원발성간암 환자 38명을 대상으로 하였으며 HBV-DNA 중합효소연쇄반응법을 이용하여 정성적 검출 그리고 luminometry법을 이용하여 정량적 검출을 하였다. 결과 : HBV-DNA 중합효소연쇄반응법과 luminometry법의 양성율은 각각 57.9%, 39.5%를 보였다. 그리고 HBsAg과 HBeAg가 동시에 양성을 보인 11명에서는 HBV-DNA 양성율이 81.8%를 보였다. 결론: HBV-DNA 중합효소연쇄반응법의 양성율이 luminometry법에 의한 양성율보다 높은 결과를 보였고 HBV-DNA 검사는 B형 간염을 조기 발견하고 치료하여 만성간질환으로의 진행을 예방하고 특히 원발성간암의 병율을 낮추는데 많이 기여할 것으로 사료되었다. Background : Primary hepatocellular carcinoma(PHCC) is the most common malignant neoplasm in most countries of Asia and Africa. Hepatitis B virus is known to be strongly related to the pathogenesis of PHCC. HBV-DNA PCR and HBV-DNA quantitation assay were attempted to apply to 38 cases of HBsAg positive PHCC. Methods : The ordinary HBV markers(HBsAg, anti-HBs, anti-HBc(Ig-G and -M), HBeAg and anti-HBe) were examined with ELISA. Qualitative screening of HBV-DNA PCR and HBV-DNA quantitation-luminometric measurement were performed. Results : Among 38 cases of HBsAg positive PHCC, positive rates for HBV DNA-PCR and HBV DNA-quantitation were 57.9% and 39.5%, respectively. And 11 cases which were positive for both HBsAg and HBeAg showed 81.8% positive rate in HBV-DNA PCR. Conclusion : For 38 cases of HBsAg positive PHCC, the positive rate for HBV DNA-PCR was higher than HBV-DNA quantitation-luminometry. In HBV-DNA PCR, both HBsAg and HBeAg positive cases showed high positive rate.

산탄총창(散彈銃創) 2예 보고

이봉우,서중석,이상용,이원태 大韓法醫學會 1999 대한법의학회지 Vol.23 No.2

Shotguns were developed as an alternative to single-missile rifle or handgun in order to enable gunner to spray a wide area with shot and thus kill birds and small animals too difficult to hit with single-missile weapons. As the popularity of shotguns grew, ammunition was developed for large game. The use of shotguns on humans has been markedly increasing in various manner of death. In forensic aspect, the shotgun wonds gave characteristic findings due to their own characteristics and medical examiners may determine the range, distance, direction and kinds of gun. When the muzzle of the shotgun is placed tightly against the surface of the abdomen or thorax, the consequent wound of entrance will be single in number and circular in shape, and will have a diameter approximately equal to that of the bore of the weapon. However, when the wound is made over a site with underlying bone, especially in the scalp, the wound may have a different appearance, showing star shaped entracce due to short to mid-range, considerable variation occurs in the appearance, showing star shaped entrance due to tears from the sides of the wound and accompanying soot and burn effect. When the muzzle is held short to mid-range, considerable variation occurs in the appearance of the wound. We report two cases of shotgun wounds which showed typical findings of contact shots and distant shots.

임신과 연관된 유방삽입물 주의 피막 구형 구축의 변화에 대한 임상적 연구

이윤호,임동헌,윤진호,강소라,김한중,배원배 大韓成形外科學會 1997 Archives of Plastic Surgery Vol.24 No.6

It has been reported that the frequency of the development of peripheral capsuler contracture after breast augmentation surgery using silicone-gel implants amounts between 25 to 50%. Various treatments to cure or prevent the capsular contracture are mow being studied and introduced, including submuscular insertion of breast implants, steroid instillation, oral intake of Vit-E, postoperative breast massage, regional injection of antibiotics, and a saline-filled implantation without gel-bleed. This paper reports, along with the literal study, on the improvement of the softening of capsular contracture condition observed from 12 patients who have undergone pregnancy and delivery after breast augmentation surgery operated at the Plastic surgery departments of Ewha University Medical Center and Seoul National University Medical Center during 1985-1995. Conceivably, the softening of the capsular contracture is attributable to the hormonal change, immunologic and inflammatory alteration, and the masking effect resulting from mammary alveolar hypertrophy. It is believed that a study should be continued on the relationship between the pregnancy and the softening of capsular contracture condition.

1-Bromoacetylpyrene 誘導體化劑를 利用한 Carboxyl基 含有成分의 分析에 관한 硏究(Ⅰ) : 高級不飽和脂肪酸의 HPLC에 依한 定量 Determination of Unsaturated Fatty Acids by HPLC

李允中,曺正吉,朴元敎,李康春 成均館大學校 科學技術硏究所 1988 論文集 Vol.39 No.1

A simple and highly sensitive method for the determination of unsaturated fatty acids (C_16:1, C_20:4, C_20:5) is described. I-Bromoacetylpyrene was used as the pre-column fluorescent labelling reagent for HPLC. Fatty acids were derivatized quantitatively into fluorescent compounds by treating with 1-bromoacetylpyrene in the presence of 18-crown- 6 in acetonitrile. The optimum conditions for the derivatization such as, concentrations of KOH, 18-crown-6, and 1-bromoacetylpyrene, reaction temperature and reaction time, were investigated. The derivatives were separated on a reversed phase column (LiChrosorb RP-8, 5 ㎛) using the tertiary mixture of acetonitrile, methanol, and water as the mobile phase. The effluent was monitored by fluorometer (excitation wavelength; 366 nm, emission wavelength; 454 nm). Linearities of calibration curve were obtained between 5.0 p mol and 40.0 p mol. The detection limit of fatty acids was 1 p mol in a 20μl of injection volume.

Hexachlorocyclohexane에 의한 肝細胞 傷害機轉과 Glutathione의 影響에 關한 超微細形態學的 硏究

李元基,黃一愚,孫泰重 慶北大學校 醫科大學 1980 慶北醫大誌 Vol.21 No.1

저자는 HCH투여로 인한 간세포의 변화를 알아보고 또 이에 대한 glutathione의 방어 효과를 알기 위하여 생쥐에 0.15%의 HCH을 1일 1회 0.1㎖, 0.2㎖를 단독으로 혹은 glutathion과 같이 7일간 투여한 후 형태학적으로 검색한 소견을 요약하면 다음과 같다. 광학현미경 소견으로는 간세포의 위축, 핵내의 공포화, 핵농축 및 핵소실등을 특징으로 하는 가역성 및 비가역성변화가 주로 간소엽의 중심대에 나타나며 이들 변화는 투여량이 많으면 다소 현저하여지고 glutathione을 같이 투여한 군이나 그렇지 않는 군과의 사이에는 차이가 없었다. 전자현미경 소견으로는 핵에 있어서는 핵 윤곽의 불규칙, heterochromatin의 증가, 핵소체의 위축, nucleolonema의 소실등 핵의 기능저하를 나타내는 소견이 주로 나타나고 분비기능과 관련되는 구조물에 있어서는 그 기능의 저하를 나다내는 rER의 감소, ribosome의 탈락, Golgi장치의 위축 및 그 내강의 VLDLP의 소실등의 현상이 나타나고 sER의 증식, glycogen 과립의 감소 내지 소실, cristae의 증가를 동반하는 mitochondria의 변형 내지 거대화, 그리고 microbody의 증가등 간세포의 해독 기능과 관련되는 구조물에 있어서는 기능항진 현상이 나타나고 그밖에 퇴행성변화로서 Cristae의 감소 내지 소실을 동반하는 mitochondria의 팽화, 세장화 및 거대화, 각종 lysosome의 증가, lipid droplet의 증가등이 나타나고 Kupffer 세포에서는 탐식능의 항진을 나타내는 현상으로 생각되는 phagosome이 심히 증가하였고 보통의 경우 관찰할 수 없는 3층 구조물이 mitochondria 내에서 관찰되었다. 이상의 소견으로 보아 HCH를 투여하면 간에 있어서 두가지의 현상이 한세포내에 같이 혹은 별도로 출현한다. 즉 HCH로 인한 간세포 상해현상으로서는 핵의 위축, cristae의 감소 내지 소실을 동반하는 mitochondria의 팽화, 세장화 및 거대화, 각종 lysosome의 출현, rER의 수포화 및 감소, rER의 ribosome의 탈락등이 일어나고 HCH를 해독하기 위한 현상으로서는 sER의 증식, glycogen 과립의 감소, cristae 증가를 동반하는 mitochondria의 변형 및 거대화, microbody의 증가등이 일어나며, 이들 변화는 투여량이 많으면 더 증가하고 glutathione의 병용투여로서 그 변화가 다소 경감되는 경향이라 생각된다. 그리고 mitochondria에서 관찰된 간 세포에서는 볼 수 없는 층상구조물에 대해서는 앞으로 더 관찰할 흥미있는 것이라 믿어진다. It is a well known fact that hexachlorocyclohexane (HCH) remains unexcreted in the liver cells and extend toxic effect to them, but the mechanism is not understood in detail. This study was carried out in an attempt to investigate the mechanism of toxic effect of HCH on liver cells by examining the ultrastructural alterations after HCH administration and also glutathione was added to HCH to see if it has any protective effect to the hepatocyte damage. Thirty-four experimental mouse weighing about 30gm were divided into 3 groups: group I was given 0.1㎖ of HCH to 3 mice and 0.2㎖ to 3 mice intramuscularly daily for 7 days, group 2 20mg of glutathione added and group 3 only the solvent, olive oil, as a control. The animals were sacrified on day 8 and on day 10. The results were summarized as follow: On light microscopic examination the liver cells revealed atrophy, intranuclear vacuolization, pyknosis and karyolysis. These changes were particulary prominent in the centrilobular zones, and were more severe in the group treated with high dosage, but no evidence of protective effect of glutathione was noted. Electron microscopically, nuclei showed irregularity of nuclear contour, increase of heterochromatin, and atrophy and loss of nucleolonema of nucleoli, Secretory organelles, showed decrease of rER, shedding of ribosome, and atrophy and loss of VLDLP in Golgi apparatus suggesting functional derangement. On the other hand, changes of organelles involved in detoxication suggested increased activity by revealing of proliferation of rER, decrease or loss of glycogen particles, distorted and enlarged mitochondria combined with increase of cristae and increase of microbody. Also degenerative changes were noted such as welling of mitochondria with decrease and loss of cristae, increase of primary and secondary lysosomes, and increase of lipid droplets. Kupffer cell showed increase of phagosome suggesting increased phagocytic activity. Thee results are suggesting that two different phenomena are occuring in the liver cells by HCH injection. The one was liver cell injury and the other was increased activity of organelles involved in detoxication. The severity of changes was more strong in higher dosage group. Administration of glutathione seemed to lessen the toxic effects of HCH in mild degree.

Gd₂O₃doped CeO₂의 미분말 합성 및 소결특성

이주신,김원중,박성용 경성대학교 공학기술연구소 1999 공학기술연구지 Vol.6 No.-

10mol% Gd₂O₃doped CeO₂ doped fine powders were synthesized by the oxalate coprecipitation method and then their powder characteristics and sintering behavior were studied. The characterization of powders has been investigated using thermogravimetry and differential thermal analysis for thermal analysis, X-ray diffraction for phase identification. Brunauer-Emmett-Teller, X-ray diffraction-line broadening and transmission electron microscopy for particle size and morphology determination. The sintering behavior were investigated by means of the sintering density measurements and scanning electron microscopy techniques. The characteristics of powders prepared by the oxalate coprecipitation method and their sintering behavior are discussed.