관상동맥 시술 도중 발생한 좌주간부 관상동맥 박리에 대한 스텐트 삽입 치료의 단장기 임상 결과 : acute and long-term results

이세환,이승환,홍명기,김영학,이철환,한기훈,송종민,강덕현,송재관,김재중,박성욱,박승정 대한내과학회 2004 대한내과학회지 Vol.66 No.6

목적 : 심도자 사용 시술과 관련된 좌주간부 관상동맥박리에 대한 적절한 치료는 아직 확실히 정립되지 않은 상태이다. 이에 본 연구는 좌주간부 관상동맥 박리에 대한 스텐트 삽입술의 단장기 임상결과를 후향적으로 분석하였다. 방법 : 좌주간부 관상동맥 박리에 대한 치료로 즉각적인 스텐트 삽입술을 시행하는 것이 안전하고 효과적인 방법임을 가설하였고, 이러한 즉각적인 스텐트 삽입을 시행한 10명의 환자를 대상으로 단장기적 임상경과를 의무기록 고찰과 전화 면담을 통해서 평가하였다. 결과 : 전체 환자 모두 처음부터 좌주간부 관상동맥에 유의한 협착을 가진 환자는 없었으며, 8명의 환자는 심도자의 조작으로 인한 박리가 발생한 경우였고(진단적 혈관 조영술 중에 3명, 유도 도자 조작 중에 5명), 나머지 2명은 다른 병변에 스텐트 삽입시술을 하는 중에 박리가 발생하였다. 이 10명의 환자에서 모두 즉각적인 스텐트 삽입술이 시행되었고, 4명의 환자에서 시술 도중 혈압 저하로 Intra-aortic Ballon Pump (IABP)를 장착하였다. 모든 환자에서 성공적으로 스텐트가 삽입되었고, 병원내 사망은 1명도 없었다. 6개월 추적 관상동맥 조영술은 8명의 환자에서 시행되었다. 혈관 조영상의 재협착(직경 협착 50% 이상)은 8명 모두에게서 관찰되지 않았으며, 퇴원 후 평균 31±25개월의 추적관찰 결과 주요 심장사건은 1건도 발생하지 않았다. 결론 : 비록 대상 환자가 적은 연구였지만 좌주간부 관상동맥 박리에 대한 스텐트 삽입술은 기술적으로 안전하고 빠르게 시행 할 수 있으며, 훌륭한 단장기적인 치료 효과를 보여준다. Background : The optimal treatment of patients with left main coronary artery (LMCA) dissection during catheter-based procedure remains uncertain. We retrospectively analyzed the acute and long-term results of bail-out stenting for LMCA dissection. Methods : In cases with significant LMCA dissection occurring during catheter-based procedure, prompt stent implantation may be safe and associated with favorable clinical outcome. We evaluated the acute and long-term results of bail-out stenting for LMCA dissection occurring during catheter-bases procedure in 1- patients. Results : Initially, there was significant stenosis of LMCA segment in these patients. Catheter-induced dissection occurred in 8 patients (during diagnostic angiography in 3 patients and guiding catheter manipulation in 5 patients). Two patients suffered dissection in the setting of stent deployment in other vessels. Therefore, bail-out stenting LMCA dissection was performed in a total of 10 patients. In 4 patients, hypotension developed and intra-aortic balloon pump was placed during procedure. Stents were successfully deployed in all patients. There was no in-hospital mortality. Six-month angiographic follow-up was performed in 8 patients. Angiographic restenosis(diameter stenosis 50%) was not observed in all patients at follow-up study. During a mean follow-up of 31±25 months after hospital discharge, there was no major adverse cardiac event (death, myocardial infarction, and target lesion revascularization). Conclusion : Bail-out LMCA stenting is technically feasible, and showed good acute and long-term results in a small series of patients.

疎水性 中空絲膜을 이용한 Cu(II)의 透過抽出

李龍珍,金萬壽,朴東源,金英一,黃德基 東亞大學校 大學院 1997 大學院論文集 Vol.22 No.-

Liquid-liquid extractions by use of microporous hollow fiber modules are fast compared with conventional extraction equipment because of the large surface area per volume. In these modules, the extractant and feed can be contacted at high speed andtwo flows are completely independent, so there are no problems with loading and channeling. In this paper, it was investigated the extractability for liquid-liquid extraction of Cu(Ⅱ) from dilute aqueous solution into D2EHPA(di-2-ethylhexylphosphoric acid), TBP(tri-n-butyphosphate) and TOA(tri-n-octylamine) as organic extractants by using the hydrophobic hollow fiber module. To determine the dependence of mass transfer rate on distribution of Cu(Ⅱ) in the module, we compared the overall mass transfer coefficient with distribution ratio. From these experiments, we identified the effect of distribution ratio on the overall mass transfer coefficient was, for the low H, the K? was increased with increasing H, but high value of H, the effect of H on K? could be negligible.

근거리 수치화상에 의한 정밀측정에서 자유망 번들조정의 효과

이진덕,최용진,장기태 金烏工科大學校 産業技術開發硏究院 1999 産業技術開發硏究 Vol.15 No.-

The vision metrology system employing still-video imagery for industrial measurement has the potential of automated measurement with high accuracy. This paper was focussed on ascertaining the impact of free-net technique in self-calibrating bundle adjustment. The practical measurement of a three dimensional test field was conducted using a vision metrology system which was composed of a high resolution still-video camera, a PC-based image mensuration algorithm and a self-calibrating bundle adjustment program. As a result, free-net technique, which does not require any control points with pre-known object space coordinates, went up about 12% in accuracy compared to traditional standard technique. Therefore free-net bundle adjustment is expected to be able to be used efficiently for industrial applications such as dimensional inspection, deformation monitoring and so on.

실관막을 이용한 중금속 추출에서 물질전달에 미치는 분배비의 영향

李龍珍,金英一,陳道源,黃德基,朴東源 동아대학교 공과대학부설 생산기술연구소 1997 生産技術硏究所硏究論文集 Vol.2 No.1

The liquid-liquid extractions by use of microporous hollow fiber membrane modules are fast compared with conventional extraction equipment. Because they have a large surface area per volume. Solute diffuses out of the feed solution, through the fibers' porous wall, and into the extractant. The extractant and feed can be contacted at high speed, there are no problems with flooding, loading and channeling. Moreover, these modules should be characterized by low investment and operating costs because of the reduced hardware and the favorable hydrodynamics which minimizes concentration polarization and membrane fouling. In this paper, it was investigated the extraction selectivities for liquid-liquid extraction of heavy metal(Cd(Ⅱ)Co(II)) from dilute aqueous solution into the eatractants(EHPNA and TBP) by using the hydrophobic hollow fiber module. We also examined the effect of distribution ratio on the overall mass transfer coefficients.

수은(Hg2+) 및 니켈(Ni2+)이 [³H]Quinuclidinyl Benzilate의 Muscarinic Receptors 결합에 미치는 영향

이정수,임시덕,배기철,이신웅 嶺南大學校 環境問題硏究所 1991 環境硏究 Vol.11 No.1

[³H]Quinuclidinyl benzilate(QNB) binds specifically to muscarinic receptors which mediate a number of important physiological reponses of acetylcholine. In the present study, the effects of ?? and ?? on [³H]QNB binding to the cerebral microsome were investigated. Microsomes were treated with ?? or ?? for 15min at 37℃ and then binding experiments were carried out. ?? and ?? inhibited [³H]QNB binding in the presence of 100pM [³H]QNB to muscarinic receptors with ?? value of 2.1 μM and 350mM, respectively. The inhibition of [³H]QNB binding by these metals was irreversible. Both ?? and ?? decreased the binding site concentration for [³H]QNB binding without affecting ?? value of [³H]QNB. These results indicate that heavy metals inactivate the muscarinic receptors with different potency.

실관형 막모듈에 의한 Hg(Ⅱ)의 분리에 관한 연구

이용진,김만수,황덕기,박동원 동아대학교 환경문제연구소 1997 硏究報告 Vol.20 No.1

By use of hollow fiber membrane module, this study examines the value of H(distribution ratio) and Kw(overall mass transfer coefficient) on the Hg(Ⅱ), and used di-2-ethylhexylphospric acid(DZEHPA), tributyl phosphate(TBP), tri-n-octylamine(TOA) as extractant, Also, shown the change of changing the acid. From these experiments and discussions, we have the results as follows. 1. In case of Hg(Ⅱ), the order of well seperated is TOA, DZEHPA, TBP. 2. Concentration decrease ratio have the straight lines for the changing of the time in each systems. So, It was know that the result coincide with theory. 3. The effect of Kw vs. H were shown that in case of H is lower than 10, H is high effect. But H is higher than 10, H is low effect.

Flux법에 의한 PZN-PNN-PT-PZ계 세라믹스의 제조 및 압전특성

이기태,남효덕 嶺南大學校工業技術硏究所 1992 연구보고 Vol.20 No.2

The quarternary system ceramics 0.5[xPb(Zn1/3Nb2/3)O3-(1-x)Pb(Zn1/3Nb2/3)O3-0.5[yPbTiO3-(1-Y)Pb-ZRO3] were prepared by flux method and compared their piezoelectric properties with conventional method. Piezoelectric properties of sample prepared by flux method were improved compared to that of conventional method. By adding PZN, morpholropic phase boundary of the sample shifted to more Zr-rich composition and showed a drop in piezoelectric properties.

방해석의 복굴절에 의한 편광

李原鎭,成德鏞,全永基,申再鉉 대구산업정보대학 1998 논문집 Vol.12 No.2

It was investigated the variation of polarization by the double refraction of light for a calcite crystal. In a calcite there is a single direction called the optics axis, which is an axis of symmetry with respect to both the crystal form and the arrangement of atoms. For a point in calcite, there are three principal sections, one for each pair of opposite crystal faces. A principal section always cuts the surfaces of a calcite crystal in a parallelogram withe angles of 71˚ and 109˚. When a beam of plane-polrized light is directed along the optic axis of calcite crystal, the plane of polarization turns steadily about the direction of the beam and emerges vibrating in some other plane than that at which it entered. The law of Malus is ralationship how the intensity transmitted by the analyzer varies with the angle that its plane of transmission makes with that of the polarizer. The pane polarization, θ was obtained from the law of Malus was 20.2˚

時變磁界 測定用 센서에 관한 硏究

이복희,백용현,박형기,정승수,전덕규 경북대학교 센서기술연구소 1992 센서技術學術大會論文集 Vol.3 No.1

알코올 사용 척도에 의한 알코올 의존의 유형과 그 특성에 관한 연구

이덕기,신진규,정영인 대한신경정신의학회 2000 신경정신의학 Vol.39 No.6

연구목적 : 알코올 사용 척도를 이용한 알코올 의존의 유형분류가 우리나라에서 가능한지, 가능하다면 그들 각각의 임상적 특성은 무엇인지를 군집분석을 통하여 구명하고자 하였다. 방 법 : 180명의 알코올 의존 입원 환자를 대상으로 알코올 사용 척도를 사용하여 얻은 결과를 군집분석을 이용하여 분류를 시도하고 각 유형의 임상적인 특징을 조사하였다. 결 과 : 1) 알코올 의존은 세 가지 유형으로 나눌 수 있었다. 1형은 알코올의 심리적, 신체적 의존과 음주로 인한 합병증 및 조절 장애가 가장 심하고, 주로 혼자 술을 마시며 폭음하는 특징을 보였다. 2형은 음주로 인한 이익이 세 유형 중에서 가장 많으며, 특히 대인관계의 맥락 속에서 주로 음주하고 지속적으로 술을 마시는 특징을 나타내었다. 3형은 상대적으로 가장 경한 형으로 금단 증상과 신체적 합병증이 문제가 되었다. 2) 세 유형간에 있어서 나이, 교육 수준, 결혼 상태, 직업유무 및 알코올 의존의 가족력의 유무는 차이가 없었다. 3) 세 유형간에 있어서 음주 문제로 인한 최초 입원시 나이, 알코올의 심리적, 신체적 의존과 음주의 합병증 정도, 음주 빈도와 음주량을 비교 분석한 결과 음주 문제로 인한 최초 입원 나이는 1형과 2, 3형 사이에서, 나머지는 세 유형 모두에서 통계적으로 유의한 차이를 보였다. 4) 세 유형간의 반사회적 성격 경향, 경계성 성격경향, 강박적 성격 경향 및 알코올 외 다른 중독성 약물의 남용 정도는 3형과 1,2형 사이에서 유의한 차이가 있었다. 우울의 정도는 1형과 3형 사이에서 유의한 차이가 있었다. 불안의 정도는 세 유형사이에 유의한 차이가 없었다. 결 론 : 알코올 사용 척도를 이용한 알코올 의존의 유형 분류가 우리나라에서도 가능하며, 각 유형은 임상적 특성에 따라 각기 다른 치료 모형과 전략의 수립이 필요함을 알수 있었다. Objectives : The Purpose of this study is to classify the type of individuals with alcohol dependence, and to examine its clinical characteristics through cluster analysis. Methods : 180 inpatients with alcohol dependence were examed with AUI, MAST, ADS, and MCMI. The classification of alcohol dependence was done through the cluster analysis. Results : 1) Patients with alcohol dependence could be classified into three types. Type 1 of alcohol dependence was the severest in terms of physical and psychological dependence on alcohol, alcohol-related problems, and loss of control, and was characterized by isolated drinking and binge drinking. Type 2 of alcohol dependence was mainly drinking on account of personal relationships, and is characterized by continuous drinking. Type 3 of alcohol dependence is relatively the mildest type, which led to withdrawal symptoms and complications. 2) There is no difference in age, educational level, marital status, occupation, family history of alcoholism among three types. 3) As a result of comparative analysis of age at the first hospitalization by drinking, physical and psychological dependence on alcohol, complications by drinking, amount of drinking, and frequency of drinking, the age at the first hospitalization by drinking showed statistically significant difference between type 1 and type 2 or type 3. 4) There was significant difference in anti-social personality trait, borderline personality trait, and obsessive-compulsive personality trait, and drug abuse tendency between type 3 and type 1 or type 2. There was a significant difference in the degree of depression between type 1 and type 3 ; there was no difference in the degree of anxiety among three types. Conclusion : It is possible to classify alcohol dependence into three types by means of AUI in Korea, and each type should require specific models of therapeutic strategies and approaches in accordance with its clinical characteristics.