외상성 교합으로 인한 어린이의 치주질환

최병재,고동현,김성오,이제호,손흥규 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.3

외상성 교합은 교합력의 결과로서 치주조직에 가해지는 손상이다. 주된 증상은 치아의 동요도이고, 통증, 타진에 민감, 열에 민감한 증상이 동반될 수 있으며 교합력에 의해 치아가 이동을 할 수도 있다. 만성으로 진행시 치아의 과도한 교모가 나타나며 방사선학적으로 치근막 공간의 비후, 치조백선의 비후, 치조골의 방사선 투과성, 치근흡수 등이 나타날 수 있다.외상성 교합은 치주질환의 원인과 관련되어 있다. 증가된 치아동요도를 야기하며 외상성 교합 자체는 치은염과 치주낭을 발생시키지 않으나 국소적 치태와 염증이 존재하고 있는 하에서 골소실, 치주낭이 발생할 수 있다. 치은퇴축은 외상성 반월, 맥콜스 팽윤, 스틸만 균열의 형태로 나타난다. 본 증례는 하악 유견치 부위의 치주질환을 주소로 내원한 5세 남아로서 상하악 유견치의 조기 접촉에 의해 하악 좌우측 유견치의 중증도의 동요도, 교합마모, 치은 퇴축, 치조골 파괴의 증상이 나타났기에 보고하는 바이다. Trauma from occlusion(TFO) is injury to the periodontal tissue as a result of occlusal forces. Mobility is a common clinical sign of occlusal trauma. In acute occlusal trauma, this may be accomanied by pain, tenderness to percussion, thermal sensitivity, and pathologic tooth migration. Chronic occlusal trauma may be marked by excessive wear and gingival recession. Radiographic finding include a widened periodontal ligament space, radiolucence and condensation of the alveolar bone, and root resorption. TFO is related to the pathogenesis of periodontal disease. It can cause increased tooth mobility. TFO itself does not initate or aggravate marginal gingivitis or initiate periodontal pockets. Active trauma can accelerate bone loss, pocket formation and gingival recession depending on the presence of local irritants and inflammation. Gingival recession associated with occlusal forces includes traumatic crescent, McCall's festoon and Stillman's cleft. TFO plays a minor role in the pathogenesis of early to moderate periodontitis. A 5-year-old male visited Yonsei University Pedodontics clinic with a chief complaint about gingival recession. Mobility, excessive wear, gingival recession were detected by clinical exam on the both mandibular deciduous canine. On the radiographic view, vertical alveolar bone loss was observed on both mandibular deciduous canine.

흰쥐의 좌골신경 절단 후 복합근활동전위 척도의 변화 양상

고현윤,박병규,박재홍,신용범,조시철 대한근전도전기진단의학회 2003 대한근전도 전기진단의학회지 Vol.5 No.1

The Protective Effects of water Extracts of ZoaGumHwan (ZGH) on the Oxidized LDL-induced Monocyte Adhesion to Human Umbilical Vein Endothelial Cells

Ko, Yu-Jin,Park, Byung-Chul,Lee, Jong-Suk,Park, Su-Young,Shin, Heung-Mook,Yoo, Bong-Kyu,Kim, Jung-Ae The Korean Society of Applied Pharmacology 2007 Biomolecules & Therapeutics(구 응용약물학회지) Vol. No.

It is well known that oxidized low-density lipoprotein (oxLDL) is the most characterized humoral factor that plays an important role in the pathogenesis of atherosclerosis. The water extract of the Korean herbal remedy, ZoaGumHwan (ZGH), which is composed of roots of Coptis chinensis Franch and fruits of Evodia officinalis Dode with the ratio of 6 to 1, reduced the in vitro oxidation of low density lipoproteins (LDL). Also, the ZGH extract and berberine, one of the major components of ZGH, significantly prevented oxLDL-induced adhesion of monocytes to human umbilical vein endothelial cells (HUVEC). Furthermore, the ZGH water extract and berberine decreased oxLDL-induced expression of CC chemokine receptor 2 (CCR2), a dominant monocyte chemotaxis receptor, in U937 human monocytic cells. The protective effects of the ZGH water extract and berberine were similar to those of simvastatin, an effective lipid-lowering drug. The results suggest that Korean herbal remedy, ZGH, seems to have protective effect against oxLDL-induced monocyte chemoattractant protein (MCP)-1/CCR2-dependent monocyte recruitment onto endothelial cells.

KMEDIA - 2 : 지능형 입출력을 지원하는 PC용 하이퍼미디어 시스템 및 멀티미디어 저작도구

황규영(Kyu-Young Whang),오영환(Yung-Hwan Oh),양현승(Hyun-Seung Yang),한태숙(Tai-Sook Han),최기선(Key-Sun Choi),이흥규(Heung-Kyu Lee),노웅기(Woong-Kee Loh),최환진(Hwan-Jin Choi),고병기(Byong-ki Ko),우균(Gyun Woo),서광준(Kwang-Jun Seo 한국정보과학회 1994 한국정보과학회 학술발표논문집 Vol.21 No.2A

본 논문에서는 PC용 하이퍼미디어 시스템인 KMEDIA-1을 확장하여 지능형 입출력을 지원하는 KMEDIA-2 (KAIST Hyper MEDIA-2)에 대하여 기술한다. 지능형 입출력이란 자연언어 질의를 통한 정보 검색, 음성 명령어 인식 및 음성 합성, 영상 인식 인터페이스를 의미한다. KMEDIA-2는 이외에 멀티미디어 객체 동기화, 스크립트 언어, wavelet 변환을 이용한 정영상 압축 및 복원 기능과 디지탈 동영상을 지원하며, 하부 저장 구조로서 객체지향 저장 시스템인 KAIST-MMDB를 사용하여 하이퍼미디어 정보를 저장한다.

일반논문 : 한,일대학생의 사고 및 의식 성향에 대한 비교연구

김흥규 ( Heung Kyu Kim ),이상란 ( Sang Lan Lee ),고길희 ( Kil Hee Ko ) 인하대학교 교육연구소 2016 교육문화연구 Vol.22 No.1

본 연구는 한·일대학생의 사고 및 의식 성향에 관한 차이를 비교, 시사점을 찾는데 목적이있다. 한국 대학생 297명, 일본 대학생 219명으로 총 516명을 대상으로 가족 및 결혼관, 사회관, 직장관, 외모 및 생활 소비습관을 묻는 총 14문항으로 구성된 질문지 조사(2013. 9 ~ 2014. 10)에대해 국가별·성별 교차분석과 카이제곱 분석을 하였다. 본 연구 결과는 다음과 같았다. 결혼과이혼에 관해 양국 대학생 모두 전통적 경향에 반하여 소극적이면서 책임감이 결여된 결혼·이혼관을 보였다. 사회관 준법성 수준은 한국대학생의 경우 특히 사회 지도층에 대해 부정적 시각이높았다. 한·일대학생 모두 정치·관료·언론 분야가 사회의 건강성을 해치는 요인이라 응답하였고 정당한 실력이나 노력으로 성공할 수 있다고 보는 견해가 양국 모두 낮아 사회에 대한 부정적 시각이 반영되었다. 불만이 있을 때 이직 가능성, 시간외 근무에 대한 태도, 업무와 무관한상사의 요구에 대한 태도를 종합할 때 한국 남자 대학생이 조직생활 적응력이 높고 신중할 것으로 보였다. 소비생활습관은 과거 기성세대의 철저한 경제관념과는 달리 일본대학생들이 생활을즐기기 위한 소비성향이 한국대학생 보다 높은 것으로 나타났다. 반면 한국대학생들이 자신 외에 타인의 외모에 신경을 쓰는 경향에서는 일본대학생들에 비해 다소 높았다. 본 연구 결과 대학생의 성숙한 가족관, 사회관, 직장관 그리고 생활소비 습관 및 외모관을 함양하기 위해 교육적접근이 필요하였다. The purpose of this study is to find implications by comparing Korean·Japanese college students` thinking and consciousness tendency. Subjects were 516 college students(297 Koreans and 219 Japanese). Survey questionnaire composed by 14 items asking their view on family, marriage, society, career, living consumption habit and appearance (2013. 9 ~ 2014. 10). Collected data was analyzed by Chi-Square Test and by-nation & by-gender cross tabulation. The results of this study are as follows. First, students of both nations proved to be contrary to traditional values of marriage and divorce, and they not only passive but also lack of responsibility. Korean students had higher negative opinion than Japanese students, especially in the social leaders` legal observance. The opinion of both Korean and Japanese students as what harms the social health, was the political, administrative, and journalistic. And they thought that possibility of success through fair capability or effort is low. This result reflect their negative view on the society. Judging from turnover intention at time of complaint, attitude toward overtime work and attitude toward their boss, it turned out that Korean male students have the highest adaptability to career life, and are the most careful. Regarding their living consumption habits, unlike the economic concepts of older generations, Japanese students have higher consumption trend for enjoying life than Koreans. Korean student`s paying to their appearance is a bit higher than that of Japanese. The reinforcement of educational program was required in order to have more mature perspective for college students on value of family, career, physical appearance and consumer lifestyle.

각종 갑상선 질환에서 혈청 Thyroxine 결합글로부린 (TBG) 의 진단적 의의

노흥규,한봉헌,이헌영,고석만,윤상룡 대한핵의학회 1981 핵의학 분자영상 Vol.15 No.2

In an attempt to evaluate the diagnostic significance of the serum thyroxine binding globulin(TBG) in various thyroid disease states, the authors measured serum T3 uptake, T3, total T4, free T4, TSH and TBG by radioimmunoassay technique, and calculated the free T4 index(FT4I) and T4/TBG ratio in 10 cases of normal subjects, 11 eases of hypothyroidism, 62 cases of euthyroidism and 37 cases of hyperthyroidism. The data were analysed in the aspects of diagnostic significance in each thyroid disease state, and the results were as follows; 1) In 10 cases of normal subjects, serum TBG was 17.4∼26.8ug/ml, FT4I was 5.1∼9.7, and T4/TBG ratio was 21.9∼49.9(Mean±S.D.). 2) 62 cases of euthyroidism with diffuse and nodular goiter, FT4I was 7.26±1.82, T4/TBG ratio was 31.47±10.42, and there were no significant difference from those of normal subjects(p〉0.5). 3) In 11 cases of hypothyroidism, the FT4I was 3.13±2.15, T4/TBG ratio was 11.3±5.31, significantly lower than normal controls(p〈0.01). 4) In 37 cases of hypsm, the FT4I was 30.0±12.01 T4/TBG ratio was 121.4±62.2, significantly higher than normal controls(p〈0.01). 5) There were significant correlations between the FT4I and T4/TBG ratio, total T4 and T4/TBG radio, in each thyroid function states. 6) The FT4I showed 100% of diagnostic value in hyperthyroidism, 89.2% in euthyroidism, and 80% in hypothyroidism group. The T4/TBG ratio showed 100% of diagnostic value in hyperthyroidism and hypothyroidism, and 80.6% in euthyroidism group. The above results suggest that T4/TBG ratio and FT4I showed same diagnostic value in hyperthyroidism group, but T4/TBG showed higher diagnostic significance than FT4I in hypothyroidism.

각종 혈액질환에서 혈청 Ferritin 치

노흥규 ( Heung Kyu Ro ),유재상 ( Jae Sang Yoo ),고석만 ( Suk Man Ko ),한봉헌 ( Bong Heon Han ),윤상룡 ( Sang Ryong Yoon ) 대한내과학회 1981 대한내과학회지 Vol.24 No.9

PDMS 쿠션을 갖는 Si 몰드에 의한 핫엠보싱 공정에서의 4인치 웨이퍼 스케일 전사성 향상

김흥규(Heung-Kyu Kim),고영배(Young Bae Ko),강정진(Jeong Jin Kang),허영무(Youngmoo Heo) Korean Society for Precision Engineering 2006 한국정밀공학회지 Vol.23 No.8

Hot embossing is to fabricate desired pattern on the polymer substrate by pressing the patterned mold against the substrate which is heated above the glass transition temperature, and it is a high throughput fabrication method for bio chip, optical microstructure, etc. due to the simultaneous large area patterning. However, the bad pattern fidelity in large area patterning is one of the obstacles to applying the hot embossing technology for mass production. In the present study, POMS pad was used as a cushion on the backside of the micro-patterned 4 inch Si mold to improve the pattern fidelity over the 4 inch PMMA sheet by increasing the conformal contact between the Si mold and the PMMA sheet. The pattern replicability improvement over 4 inch wafer scale was evaluated by comparing the replicated pattern height and depth for POMS-cushioned Si mold against the rigid Si mold without POMS cushion.

국제해상운송상 선박우선특권에 관한 연구

최흥섭 ( Heung Seob Choi ),고명규 ( Myung Kyu Ko ) 한국국제무역학회 2001 國際貿易硏究 = Journal of international trade studies Vol.7 No.2

선박의 담보제도에는 선박우선특권과 선박저당권을 들 수 있다. 이 글에서는 선박우선특권을 중심으로 국제조약, 현행상법상의 규정 및 입법배경을 살피고 1993년 신조약 성립에 따른 개정방향도 간단히 언급하고자 한다. 선박우선특권은 특정한 조건만 충족되면 발생하는 법정담보물권이다. 문제는 이 우선특권이 선박저당권에 앞서서 적용이 되기 때문에 정당하고 합법적인 공시절차를 거친 선박저당권(선박은 워낙 고가이기 때문에 육상의 부동산처럼 선박에 대해서도 약정 담보물권인 저당권을 설정하는 것이 해상관습이다)자의 권리를 침해한다는 것이다. 이에 이 글은 선박우선특권의 합리성에 대해 고찰하고 현행상법에서 삭제될 부분도 언급하고 있다. 그러나 해상운송의 특성상 선박우선특권은 인정되지 않을 수 없는 제도이다. 다만 문제는 그 범위를 어떻게 축소·조정하느냐인 것이다. 현행 우리상법은 1926년 조약을 중심으로 입법하고 있으나 1993년 조약을 수용하여야 할 것으로 보인다. 그러나 이는 각국의 이해관계가 얽힌 문제로 각국의 수용방안을 고려하여 우리도 입법의 방향을 잡아야 할 것이다. Generally, Marine Enterprise has given its ship as security system for Maritime Lien and Ship Mortgage. Maritime Lien affords to with the assent of international a signatory country. But maritime lien is always put before the other security system(for example - ship mortgage). This paper deals with Maritime Lien and try to research into matter throughly. This paper take a good look at provision with the Commercial Law and refer to improvement it. It suggests the reasonable law-making direction. Therefore no matter what, Maritime Lien will curtail of proper compass except necessary part. however, That matter related to not only our country problem but each country. So, we must watch every country.

뇌실내 Calcitonin 투여가 위산분비에 미치는 영향에 관한 연구

최흥재(Heung Jai Choi),홍사석(Sa Suk Hong),김경환(Kyung Hwan Kim),이상인(Sang In Lee),권상옥(Sang Ok Kwon),안영수(Young Soo Ahn),장우익(Woo Ick Jang),연규홍(Kyu Hong Yeon),고창만(Chang Mann Ko) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.4

N/A Peptides that are common to the brain and gut are thought to plav intermediary roles as neurotrans- mitters or neuromodulators in the regulation of gut function. Calcitonin is a polypetide hormone of 32 amino acid residues. Intracerebroventricular (ICV) administration of calcitonin does not alter plasma calcium or phosphorus concentrations. Recently, much evidence is accumulating to suggest that calcitonin may inhibit gastric acid secretion by a central action. But the neurohumoral pathways mediating antitsecretory effects of calcitonin in rats are not well elucidated. In the present study, using a gastric perfusion technique, effects of ICV administration of calcitonin on gastric acicl secretion and stress ulceration and its mechanism were investigated in rats. The results obtained are as follows: 1) ICV administration of calcitonin suppressed basal gastric acid secretion in a dose-dependent manner. 2) Gastric acid secretion stimulated by histamine, bethanechol or pentagastrin was not suppressed by ICV administration of calcitonin. 3) Gastric acid secretion stimulated by TRIl was markedly suppressed by ICV administratioti of calcitoninl. 4) Bilateral vagotomy did not influence calcitonin-induced gastric acid suppressionl. 5)Pretreatment metyrosine did not itnfluence cailcitoinin-induced gaitric acid suppression. 6) Intravenous administration of high dose (25 IU) of calcitonin suppressed gastric acid secretion. Central administration of calcitonin was approximately 250 times more sensitive than intravenous administration. 7) Stress ulcers induced by cold restraint and TRH administration were diminished by ICV admitnistration of calcitonin. In this study it is demonstrated that calcitonin suppresses gastric acid secretion, and this inhibitory effcct is centrally mediated. In particular, calcitonin suppresses TRH induced gastric acid secretion and stres ulcer formation. And it is suggested that calcitonin seems to play an inhibitorv role in gastric acid secretion as a neuromodulator in the central nervous system.