임부의 연령에 따른 보완대체요법에 관한 인식 태도 경험 비교 연구

김연진,김지연,노경민,신혜리,유예지,이지민,장희조,정아인,최소정,강숙정,이향연,민혜영 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50

Purpose: This study aims to test if the age of pregnant women affects the perception, experience, and attitude towards complementary alternative therapy (CAT), by investigating the perception, experience, and attitude of pregnant women under the age of 35, and above 35 (Advanced Maternal Age). The study will 1) find the general characteristics of pregnant women under and over the age of 35 2) compare the perception, behavior, and experience of pregnant women under and over the age of 35, and 3) find the comparison of the perception, behavior, and experience according to the general characteristics of pregnant women under and over the age of 35. Method: The subjects of this study are composed of 44 women under the age of 35 and 44 women above the age of 35, totaling 88 pregnant women visiting midwiferies, obstetrics and gynecology, and baby fairs in Seoul and Gyeong-Gi area. Data for this study was collected from November 28, 2015 to January 6, 2016 for 40 days. The collected data analyzed mean, standard deviation, t test, ANOVA, and chi-square by using SPSS 23.0. Result Results show that there is a significant difference in the perception, attitude, and experience of the two-sample groups in the use of CAT. The question of “what is most necessary when applying CAT in a hospital clinical environment” for the perception criteria came out with the results of t=9.980, p<.05. For the attitude, results showed that the answers of pregnant women under the age of 35 displayed a more positive attitude towards CAT. (t=2.421, p<.05) Lastly, in the experience section, pregnant women under the age of 35 showed more CAT use than the other sample group. Conclusion Results have shown that there is a difference in the perception, behavior, and experience between the two sample groups. Therefore further research on the efficacy and the adverse effects of CAT needs to be done.

음성 인식 헬스케어 시스템

신진우,조우승,조성빈,김재훈,정지은,사예지,백경동,박동규 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2

As modern people's interest in health grows, wearable healthcare-related technologies that can collect biometric information and receive health-related services regardless of time and place are developing. This paper proposes the healthcare system based on voice recognition function. Unlike conventional wearable healthcare systems, the proposed system provides real-time telemedicine and diagnosis and the direct connection with doctors is possible through it. And almost all functions of the application in it are operated with voice commands to lower user access barriers. Because it deals with personal information including medical information, encryption algorithms have been applied between all data movements. Finally, the healthcare system proposed in this paper is expected to increase convenience in health care and reduce the medical gap.

Multicenter Retrospective Analysis of Intraperitoneal Paclitaxel and Systemic Chemotherapy for Advanced Gastric Cancer with Peritoneal Metastasis

Kim, Dong-Wook,Jee, Ye Seob,Kim, Chang Hyun,Kim, Jin-Jo,Park, Sungsoo,Choi, Sung Il,Park, Joong-Min,Kim, Jong-Han The Korean Gastric Cancer Association 2020 Journal of gastric cancer Vol. No.

Purpose: The objective of the present retrospective analysis was to describe the experience of intraperitoneal (IP) paclitaxel and systemic chemotherapy in patients with peritoneal metastasis (PM) of advanced gastric cancer (AGC) in a multicenter setting in Korea. Materials and Methods: The medical records of patients with AGC, who were diagnosed with PM between January 2015 and December 2018, were reviewed. IP catheter was placed in the pouch of Douglas and was used for the administration of IP paclitaxel chemotherapy. Results: We reviewed the clinical outcomes of IP paclitaxel and systemic chemotherapy administration in 82 patients at six institutions in Korea. Mean number of IP chemotherapy cycles was 6.6. The mean peritoneal cancer index (PCI) was 21.9. Postoperative complications related to IP catheter and port were observed in 15 patients. The overall median survival was 20.0 months. A significant difference was observed in the survival rate according to the ascites grade (grade I and II, 24.1 months; grade III and IV, 15.3 months; P=0.014) and PCI grade (grade I, 25.6 months; grade II and III, 16.3 months; P=0.023). Conclusions: The feasibility of IP paclitaxel and systemic chemotherapy administration was demonstrated in this experience-based retrospective analysis suggesting that the procedure is beneficial in patients with PM of AGC.

Introduction to Oncoplastic Surgery for Breast Cancer

Jee Ye Kim 대한외과학회 2022 대한외과학회 학술대회 초록집 Vol.2022 No.11

Risk of cardiovascular thrombotic event associated with concomitant use of proton pump inhibitors and dual anti-platelet therapy in patients with acute myocardial infarction

( Ye Jee Kim ),( Nam Kyong Choi ),( Jong Mi Seong ),( Joong Yub Lee ),( Mi Sook Kim ),( Ju Young Shin ),( Sun Young Jung ),( Hong Ji Song ),( Byung Joo Park ) 대한보건협회 2013 대한보건협회 보건종합학술대회 Vol.2013 No.-

Objective : Concomitant use of proton pump inhibitor (PPI) is recommended to reduce the gastrointestinal bleeding events in high risk patients received dual antiplatelet therapy (DAPT) with aspirin and clopidogrel. In recent years, some or all PPIs might decrease the platelet inhibitory effects of anti-platelet drugs there has been controversy about the impact of clinical outcomes in a real world setting. To evaluate the association between use of PPI and risk of cardiovascular thrombotic event (CVTE) in acute myocardial infarction (AMI) patients receiving DAPT. Methods: Using the Korean Health Insurance Review and Assessment Service database, a population-based retrospective cohort study was conducted in patients aged 30 to 99 years old, received DAPT from January 1, 2008 to December 31, 2010 after hospitalization for AMI. The index date was defined as the first prescription date of DAPT within 90 days after discharge. Patient who received PPI treatment within a year after the index date classified as PPI user. We matched each PPI user to one non-user using a propensity score. The Cox proportional hazards model was used to compare the risk of hospitalization for CVTE including acute myocardial infarction, ischemic stroke and transient ischemic attack in users and nonusers of PPIs until December 31, 2011. Results: We identified 25,264 AMI patients received DAPT with aspirin and clopidogrel, 16.6% of whom were PPI user and after matching by propensity score, 4,051 patients remained in each group. During a mean follow-up of 1.02 years, the overall incidence rate of hospitalization for CVTE was 281/1,000 person-years for PPI user and 219/1,000 person-year for PPI non-users. Compared to non-users, the adjusted hazard ratios (95% confidence interval) of PPI users for CVTE was aHR 1.22 (1.14-1.32). In the subgroup analyses, there were no significant differences in risk of CVTE irrespective of gender, age, PCI performed, hypertension and diabetes mellitus. Conclusion: In this study of AMI patients, concomitant use of PPI and DAPT increased the risk of hospitalization for CVTE. Further studies are needed to confirm these findings.

Effect of tiotropium inhaler use on mortality in patients with tuberculous destroyed lung: based on linkage between hospital and nationwide health insurance claims data in South Korea

Kim, Ho Cheol,Kim, Tae Hoon,Kim, Ye-Jee,Rhee, Chin Kook,Oh, Yeon-Mok BioMed Central 2019 Respiratory research Vol.20 No.-

<P><B>Background</B></P><P>Although bronchodilator inhaler therapy can improve lung function in patients with tuberculous destroyed lung (TDL), its effect on mortality has not been studied. We evaluated the effect of tiotropium inhaler therapy on mortality in patients with TDL.</P><P><B>Methods</B></P><P>A retrospective cohort of 963 patients with TDL was followed for up to ten years by linking hospital and nationwide health insurance claims data. We compared patients receiving tiotropium inhaler with patients without tiotropium after matching with propensity scores. In addition, we elucidated the risk factors of mortality using Cox proportional hazards model.</P><P><B>Results</B></P><P>After the propensity score matching, the baseline characteristics were balanced in both the tiotropium group (<I>n</I> = 105) and the non-tiotropium group (n = 105); including mean age (63.9 vs. 64.4 years, <I>P</I> = 0.715), mean forced expiratory volume in 1 s (FEV<SUB>1</SUB>) (45.0 vs. 45.3%, <I>P</I> = 0.903), and others. After the propensity score matching, the tiotropium group showed better survival than the non-tiotropium group (median survival period: not reached for the tiotropium group vs. 7.24 years for the non-tiotropium group, Prentice-Wilcoxon test, <I>P</I> = 0.008). Multivariate Cox proportional hazard analysis revealed that tiotropium inhaler usage was associated with lower risk of mortality in the multivariate analysis (HR, 0.560; 95% CI, 0.380–0.824; <I>P</I> = 0.003) after adjusting age, sex, BMI, smoking history, mMRC dyspnea score, Charlson Comorbidity Index, concomitant COPD diagnosis, FEV<SUB>1</SUB>, X-ray severity score, and home oxygen usage.</P><P><B>Conclusions</B></P><P>Our results suggest that tiotropium inhaler is associated with decreased all-cause mortality in TDL. Further prospective study is required for validation.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (10.1186/s12931-019-1055-5) contains supplementary material, which is available to authorized users.</P>

Is Liver Resection Justified for Patients with Liver Metastasis from Breast Cancer?

Jee Ye Kim,Joon Seong Park,Jae Keun Kim,Dong Sup Yoon 한국간담췌외과학회 2012 한국간담췌외과학회 학술대회지 Vol.2012 No.4

Changes in the Long-term Prognosis of Crohn’s Disease between 1986 and 2015: The Population-Based Songpa-Kangdong Inflammatory Bowel Disease Cohort Study

Ye Byong Duk,Hong Sung Noh,Seo Seung In,Kim Ye-Jee,Cha Jae Myung,Rhee Kyoung Hoon,Yoon Hyuk,Kim Young-Ho,Kim Kyung Ho,Kim Kyung Ho,Jeong Seung Kyu,Lee Ji Hyun,Park Hyunju,Kim Joo Sung,Im Jong Pil,Kim 거트앤리버 소화기연관학회협의회 2022 Gut and Liver Vol.16 No.2

Background/Aims: The long-term course of Crohn’s disease (CD) has never been evaluated in non-Caucasian population-based cohorts. The aim of the present study was to evaluate the longterm prognosis of Korean CD patients in the well-defined population-based Songpa-Kangdong inflammatory bowel disease cohort. Methods: Outcomes of disease and their predictors were evaluated for 418 patients diagnosed with CD between 1986 and 2015. Results: During a median of 123 months, systemic corticosteroids, thiopurines, and anti-tumor necrosis factor (TNF) agents were administered to 58.6%, 81.3%, and 37.1% of patients, respectively. Over time, the cumulative probability of starting corticosteroids significantly decreased (p=0.001), whereas that of starting thiopurines and anti-TNFs significantly increased (both p<0.001). The cumulative probability of behavioral progression was 54.5% at 20 years, and it significantly decreased during the anti-TNF era. Intestinal resection was required for 113 patients (27.0%). The cumulative probabilities of intestinal resection at 1, 5, 10, 20, and 25 years after CD diagnosis were 12.7%, 16.5%, 23.8%, 45.1%, and 51.2%, respectively. Multivariable Cox regression analysis identified stricturing behavior at diagnosis (adjusted hazard ratio [aHR], 2.70; 95% confidence interval [CI], 1.55 to 4.71), penetrating behavior at diagnosis (aHR, 11.15; 95% CI, 6.91 to 17.97), and diagnosis of CD during the anti-TNF era (aHR, 0.51; 95% CI, 0.35 to 0.76) as independently associated with intestinal resection. The standardized mortality ratio among CD patients was 1.36 (95% CI, 0.59 to 2.68). Conclusions: The long-term prognosis of Korean patients with CD is at least as good as that of Western CD patients, as indicated by the low intestinal resection rate. Moreover, behavioral progression and intestinal resection rates have decreased over the past 3 decades.

Higher Physical Activity Is Associated with Increased Attentional Network Connectivity in the Healthy Elderly

Kim, Geon Ha,Im, Kiho,Kwon, Hunki,Seo, Sang Won,Ye, Byoung Seok,Cho, Hanna,Noh, Young,Lee, Jong Min,Kim, Sung Tae,Park, Sang Eon,Kim, Hojeong,Hwang, Jung Won,Kang, Sue J.,Jeong, Jee Hyang,Na, Duk L. Frontiers Media S.A. 2016 FRONTIERS IN AGING NEUROSCIENCE Vol.8 No.-

<P>The purpose of this study was to demonstrate the potential alterations in structural network properties related to physical activity (PA) in healthy elderly. We recruited 76 elderly individuals with normal cognition from Samsung Medical Center in Seoul, Korea. All participants underwent the Cambridge Neuropsychological Test Automated Battery and 3.0T brain magnetic resonance imaging (MRI). Participants were subdivided into quartiles according to the International Physical Activity Questionnaire scores, which represents the amount of PA. Through graph theory based analyses, we compared global and local network topologies according to PA quartile. The higher PA group demonstrated better performance in speed processing compared to the lower PA group. Regional nodal strength also significantly increased in the higher PA group, which involved the bilateral middle frontal, bilateral inferior parietal, right medial orbitofrontal, right superior, and middle temporal gyri. These results were further replicated when the highest and the lowest quartile groups were compared in terms of regional nodal strengths and local efficiency. Our findings that the regional nodal strengths associated with the attentional network were increased in the higher PA group suggest the preventive effects of PA on age-related cognitive decline, especially in attention.</P>

Treatment Outcomes of Patients With Ruptured Abdominal Aortic Aneurysms

Kim Hyangkyoung,Kwon Tae-Won,Cho Yong-Pil,Gwon Jun Gyo,Han Youngjin,Lee Sang Ah,Kim Ye-Jee,Kim Seonok 대한의학회 2023 Journal of Korean medical science Vol.38 No.39

Background: Ruptured abdominal aortic aneurysm (rAAA) is a serious complication of abdominal aortic aneurysm associated with high operative mortality and morbidity rates. The present study evaluated the perioperative and long-term outcomes of Korean patients with rAAA based on national health insurance claims data. Methods: The National Health Insurance Service (NHIS) database was searched retrospectively to identify patients with rAAA who underwent endovascular aneurysm repair (EVAR) and open surgical repair (OSR) from 2009 to 2018. Perioperative (≤ 30 days), early postoperative (≤ 3 month), and long-term (> 3 month) survival, reinterventions, and complications were assessed. Results: The search identified 1,034 patients with rAAA, including 594 who underwent EVAR and 440 who underwent OSR. When the study period was divided into two, the total numbers of patients with rAAA, patients who underwent EVAR, and octogenarians were higher during the second half. The perioperative mortality rate was 29.8% in the EVAR and 35.0% in the OSR group (P = 0.028). Hartmann’s procedure for bowel infarction was performed more frequently in the OSR than in the EVAR group (adjusted odds ratio, 6.28; 95% confidence interval [CI], 2.33–21.84; P = 0.001), but other complication rates did not differ significantly. All-cause mortality during the entire observation period did not differ significantly in the EVAR and OSR groups (adjusted hazard ratio, 1.17; 95% CI, 0.98–1.41; P = 0.087). Abdominal aortic aneurysm-related reintervention rate was significantly lower in the OSR group (adjusted hazard ratio, 0.31; 95% CI, 0.14–0.70; P = 0.005). Conclusion: Although EVAR showed somewhat superior perioperative outcomes for rAAA, the long-term outcomes of EVAR after excluding initial 3 months were significantly worse than OSR. When anatomically feasible for both treatments, the perioperative mortality risk and reasonable prospects of long-term survival should be considered in rAAA.