放射線이 생쥐生殖細胞에 미치는 影響에 關한 硏究

千基貞,柳炳善,鄭圭會,鄭海元,李鉦浩 대한방사선 방어학회 1985 방사선방어학회지 Vol.10 No.1

The objectives of present study is to investigate genetic damage of radiation in mammalian male germ cell and to establish available screening method for determining genetic hazard by radiation. Several methods were employed to measure the genetic damage of radiation as follows: Sperm head counts, frequency occurrence of sperm with abnormal head shape, fertility, activity of LDH-X, and the induction of unscheduled DNA synthesis (U.D.S.) in male mouse were performed with the passing of time after irradiation by making use of the sequence of event that occurs during spermatogenesis. Sperm head counts and activity of LDH-X in testes were gradually reduced by increased radiation dose and with the passing of the time after irradiation. Frequency occurrence of sperm with abnormal head shape, sterile period, and the induction of unscheduled DNA synthesis were increased by increased radiation dose. It is suggested that since germ cell is a direct reflection of genetic complement, the use of male germ cell is rapid and convenient method for measuring genetic damage by radiation.

남자 초·중학생의 무산소성 작업능력과 무산소성 파워의 관계

정동식,정덕조,정성태,이병근,전태원,김은혜,이동규,정동춘 師範大學 體育硏究所 1998 서울大學校 體育硏究所論集 Vol.19 No.2

The critical power(CP) is the highest intensity to sustain for a long time without a fatigue. The anaerobic work capacity(AWC) is the highest anaerobic capacity to be provided by anaerobic energy system without the infection of hypoxia. The purpose of this study was to determine the relationship between AWC and AnP and to verify the validity of AWC. The subjects were consisted of 10 elementary and 10 middle school male students(12.8±1.3yrs, 159.3±12.1㎝, 49.4±11.8㎏). The critical power and anaerobic work capacity were calculated by work-time relationship after four cycle ergometry test to fatigue from 1 to 10 minute. The anaerobic power included Margaria-Kalmen test, Sargent jump and Wingate test. The main finding were as follows. The AWC of elementary and middle school students. were 6.47±2.63KJ and 11.10±3.01KJ. The AWC of elementary students was 58.3% of the middle school students's one. The AnP of elementary students were 47.2∼66.5% of the middle school students's one. And there were high correlation between AWC and AnP(0.64∼0.87, P<0.01). This study showed that AWC is useful index on AnP both elementary and middle school students.

임플란트 식립을 위한 상악동 점막 거상술의 결과

천상득,정보연,이승은,윤홍식,진병로 영남대학교 의과대학 2003 Yeungnam University Journal of Medicine Vol.20 No.2

Background: Although dental implantation has become widespread and acceptable treatment for dental prosthodontics, maxillary posterior jaw region is often complicated by the pneumatization of the maxillary sinus and physiological resorption of the alveolar bone. When this occurs, the residual bone between the floor of the sinus and the crestal ridge is inadequate for the placement of implants. The sinus elevation procedure provides a way to increase the amount of available bone and to allow the placement of longer implants. Materials & methods: We studied 11 patients requiring the implant placements and the maxillary sinus elevation simultaneously from 1996 to 2003 in our clinic. Nine patients were males and two patients were females, aged from 39 to 72(mean=51.6). Four patients had medical compromised states; angina pectoris, diabetes, hypertension, hepatitis. Patients didn't show any pathologic findings clinically or radiographically. We studied the success and survival rate of implants, factors increasing the osseointegrating capacity of implants. Results: The success rate of osseointegration of implants was 93%. At least 6 months after loading on implants, the survival rate of implants was 78.5%. Autogenous bone graft and adequate residual bone height(>6mm) increased survival rate of implants. Conclusion: Successful implant placement with maxillary sinus elevation mainly depends on sufficient residual bone height, healthy maxillary sinus, autogenous bone graft.

通度寺 進入空間을 통해서 본 傳統景觀의 現代的 受容에 관한 考察

鄭基浩,韓炳權,全美璟 成均館大學校 科學技術硏究所 1992 論文集 Vol.43 No.1

Traditional landscapes were effected on the characteristics of nature and culture and have created distinct landscapes, while todays such attributes are becoming obscure as technology. In aspect of the contermperary applications of traditional landscapes, the cognitive qualities of observers was researched, which is about the components of entrance space in Tongdo Teple by phenomenological approach. The results of this can be summarized as follows : 1. Old components were not perceived and effected on the behavior of observers. 2. Cognitive qualities were varied from the attributes of space in and out. 3. Artificial features that related to contemporary life were perceived easily. As there were old and contemporary features to gether, the existence of old things is to be obscure relatively.

체육 서비스조직의 리더십유형과 직무만족 및 조직유효성 간의 관계

천길영,남궁완,최병학,박효찬,홍승달,정석현 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The purpose of the study was to examine the relationship among style of leadership, job satisfaction, and efficacy of sport service organization. In order to achive this purpose three reaserch questions were established. Participants for this study were 300 of 23-50 overaged public workers. Of participations valid data were 279. They completed a modified inventory of the style of leadership, job satisfaction and efficacy of sport service organization. More details, style of leadership Scale modified by Ahn(2000), job satisfaction by Ahn (2000) and efficacy of sport service organization by Kim(2001) were using after remodifing scale to investigate the purpose of this study. Results were analysed in quantitative approaches. Data were collected through self-administered survey. The most three meaningful results of the study were as follows; First, there was influenced to relationship between style of leadership and job satisfaction. Second, there was influenced to relationship between style of leadership and efficacy of sport service organization. Third, there was influenced to relationship among style of leadership, job satisfaction, and efficacy of sport service organization.

제2형 당뇨병 환자에서 비만 지수와 죽상경화증 위험인자들과의 상관성

정병천,박순홍,이주영,이신원,정성창,김정국,하승우,김보완 대한비만학회 2003 The Korean journal of obesity Vol.12 No.2

연구배경: 비만은 제2형 당뇨병의 중요한 병인이면서 죽상경화성 동맥질환의 위험인자인 인슐린 저항성, 지질대사 이상 및 고혈압의 원인으로도 인정되고 있다. 한편 비만에 의한 대사성 및 혈관 합병증은전신적 지방량의 증가보다 복강내 지방축적이 병인적 중요성을 가지고 있다고 한다 그러나 국내의 제2형 당뇨병 환자를 차상으로 비만과 이들 죽상경화증 위험인자와의 상관관계를 연구 조사한 성적은 많지않다. 이에 제2형 당뇨병 환자에서 전신적 비만과 복강내 지방 축적을 반영하는 각각의 신체계측지수들과 죽상경화증 위험인자와의 상관성을 검토함으로써 국내 제2형 당뇨병 환자의 비만도가 대사성 및 혈관성 합병증에 미치는 영향과 신체계측지수들의 임상적 가치를 평가하고자 하였다. 방법 : 제2형 당뇨병 환자 425명 (남자 196명, 여자 229명)을 차상으로 하였다 임상적 단백뇨가 있거나 인슐린 치료, 혈압강하제 또는 지질대사개선제를 복용하는 환자는 제외시켰다. 전신 비만은 체용적지수 그리고 피부두겹 두께로 산출한 체지방률을, 복강내 지방축적도는 허리둘레 및 요둔위비를 이용하였다. 죽상경화증의 위험인자로는 혈당 조절 정도를 나타내는 공복 혈당과 당화혈색소 농도, 인슐린 저항성을 나타내는 공복 인슐린 및 C-peptide 농도, 지질 대사 상태를 나타내는 총 콜레스테롤, 중성지방, 고밀도지단백 콜레스테롤 및 저밀도지단백 콜레스테롤 농도 그리고 수축기 및 이완기 혈압을 선택하였다. 전신 비만지수 및 복부 비만지수와 이들 위험인자와의 상관관계는 연령과 당뇨병 이환기간을 보정하고 편상관분석법을 사용하였다. 결과: 1 여성군에서 남성군에 비해 체용적지수(24.2 대 23.0kg/㎡, p<0.01) 및 체지방률(23.8 대13.5%, p<0.01)은 다소 높았으나 허리둘레 (87.0 대 85.8 cm)와 요둔위비 (0.96 대 0.96)는 차이가 없었다. 2. 인슐린 저항성을 반영하는 공복 인슐린 및 C-peptide 농도는 체용적지수. 체지방률, 허리둘레 및 요둔위비가 커질수록 증가하는 양의 상관관계를 보였다(상관차수 0.21∼0.42, 모두 p<0.05). 3. 혈청 지질중에는 고밀도지단백 콜레스테롤만이 남성 환자군에서 비만지수들과 약한 음의 상관성을 보이는 경향이었고, 총 콜레스테롤 및 중성지방농도는 상관성이 없었다. 4. 수축기 및 이완기 혈압은 남성군에서만 체용적지수. 체지방률, 허리둘레 및 요둔위비가 커질수록 상승하는 양의 상관관계를 보였다(상관차수 0.21∼0.33, 모두 p.0.05). 결론. 국내 제2형 당뇨병 환자들의 전신 비만도 및 복부 비만도가 서구인에 비해 심하지는 않으나 포도당 대사, 인슐린 저항성, 지질 대사 및 고혈압에 위해한 영향을 미칠 수 있는 수준에 이르고 있으며 이는 결국 죽상경화증의 위험인자로도 작용하게 될 것임을 시사한다고 하겠다. 그리고 신체계측을 통한전신 비만 및 복부 비만 지수 모두가 당뇨병 및 죽상경화증의 위험을 간접적으로 예견하는 유용한 척도가 될 수 있을 것이다. Background: Obesity is the powerful risk factor for type 2 diabetes and also associated with a significantly increased risk of insulin resistance, dyslipidemia, hypertension and atherosclerosis. Although obese individuals have these diseases, the relationship between obesity and these diseases was not certain until regional fat distribution was taken into account. Reports about the relationship between obesity and the risk factors of atherosclerosis in type 2 diabetics in Korea are very rare. To evaluate the relative importance of anthropometric indices on the development of atherosclerosis and obesity-related metabolic and vascular complications, the correlations of these indices with the risk factors for atherosclerosis were studied. Methods: Patients with type 2 diabetes mellitus (n=425, male 196, female 229) who not used antihy- pertensives or anti-lipidemic agents were investigated. Body mass index (BMI) and percentage of body fat (%BF) estimated by skinfold-thickness in assessing generalized adiposity, and waist circumference (Wc) and waist-to-hip ratio (WHR) in assessing visceral adiposity were taken as anthropometric indices. We included the indicators of glycemic control (fasting blood sugar and HbAlc), insulin resistance (fasting serum insulin and C-peptide concentrations), lipid abnormalities (serum total cholesterol, triglyceride, HDL-cholesterol, and LDL-cholesterol concentrations), and systolic and diastolic blood pressure as risk factors for the development of atherosclerosis. Partial correlations of the anthropometric indices with those risk factors were investigated with adjustment of age and duration of illness. Results: 1. BMI and %BF in female patients group were higher than those in male (24.2 vs 23.0 kg/㎡, 23.8 vs 13.5%, respectively, p<0.01 in all) although Wc and WHR were similar between both groups. In general, both body adiposity and abdominal obesity in them were much lower than in the Western. 2. Serum insulin and C-peptide levels were positively correlated with BMI, %BF, Wc and WHR (r=0.21~42, p<0.05 in all). 3. Serum total cholesterol, triglyceride and LDL- cholesterol were not correlated with any anthropometric indices. A weak negative correlation of serum HDL-cholesterol with these indices was found in male patients group. 4. Both systolic and diastolic blood pressures were positively correlated with all these indices only in male group (r=0.21~33, p<0.05 in all). Conclusion: These results suggested that the severity of both generalized and visceral adiposity in these patients with type 2 diabetes mellitus were only mild but adiposity with abdominal distribution of body fat in diabetes mellitus could be a significant risk factor of developing atherosclerosis. In clinical practice, these anthropometric indices indicating general adiposity and abdominal obesity may provide useful information for predicting disease risks, especially of diabetes and cardio- vascular disease indirectly.

제대혈중 납농도와 신생아 신경행동평가

김정아,김성아,이채용,정상재,천병렬 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.1

목적: 제대혈중 납농도가 신생아 행동평가에 미치는 영향을 평가하고자 하였다. 방법: 구미지역 1개 종합병원 신생아실에서 정상 분만한 신생아 55명을 연구대상으로 선정하였다. 납농도는 신생아의 제대혈에서 채취하여 분석하였고, 행동평가는 생후 1일째와 생후 1개월째에 브레즐톤 신생아 행동평가(Neonatal Behavioral Assess-ment Scale, 이하 NBAS)를 이용하여 시해하였다. 산모의 교육정도, 산모의 흡연유무, 산모의 간접흡연 유무, 남편의 흡연유무, 직업에 대한 생후1개월째 외래방문 시 어머니들을 대상으로 면담설문조사를 실시하였다. 결과: 연구대상자들의 평균 제대혈중 납농도는 3.88±0.70 μg/dl으로 의학적으로 중독증상을 일으키거나 행동에 장애를 줄 수 있는 농도에 미치지 않는 낮은 농도였다. 중앙값(4 μg/dl)을 근거로 두 군으로 나누었다. 일반적 특성에 따른 두 군 간의 유의한 차이는 없었다. 생후 1일째의 NBAS는 영역군집별로 두 군 간에 유의한 차이는 없었으나, 생후 1개월째의 NBAS는 4 μg/dl미만인 군이 4 μg/dl 이상인 군에 비해 운동성 영역과 상태조직력 영역의 군집점수가 유의하게 높았다. 생후 1일째의 NBAS 중 항목별로 세분하여 비교한 결과, 4 μg/dl 미만인 군이 4 μg/dl 이상인 군보다 상태조직력 영역중 최고흥분도달상태점수만이 유의하게 높았다. 그러나 생후 1개월째의 NBAS는 사회성-상호작용 영역 중 생물성시각적 자극, 무생물성시각적 자극, 무생물성청각적 자극에서, 운동계 영역 중 활동수준에서, 상태조직력 영역중 최고흥분도달상태와 상태가변성에서 4 μg/dl 미만인 군의 점수가 4 μg/dl 이상인 군보다 유의하게 높았다. 검사시기에 따른 두 군간의 변화의 정도 차이를 생후 1일째의 신경행동평가 점수를 공변량으로 조정한 후 평가한 결과, 납농도에 따른 두 군간에 유의한 차이가 있는 항목들은 사회성-상호작용 영역에서는 생물성시각적 자극, 무생물성시각적 자극, 무생물성청각적 자극이었다. 운동계 영역 중에서는 활동수준이, 상태조직력 영역에서는 최고흥분도달상태와 상태가변성이었다(p<0.05). 결론: 신생아의 평균 제대혈중 납농도의 평균이 3.88 μg/dl으로 상당히 낮았다. 그러나 제대혈중 납농도가 4 μg/dl 미만인 군과 4 μg/dl 이상인 군의 생후 1일째와 생후 1개월 후의 신경행동학적 평가 결과를 비교하였더니 생물성시각적 자극, 무생물성시각적 자극, 무생물성청각적 자극, 활동수준, 최고흥분도달상태, 그리고 상태가변성의 항목에서 차이를 보였다. 이로써 납의 저농도 노출이 신생아의 신경행동학적 기능에 영향을 미칠 가능성이 있음을 알 수 있다. Objectives: To investigate the relation between umbilical cord blood lead level lower than 10 μg/dl and neonatal neurobehavioral performance. Methods: Umbilical cord blood lead level, as an indicator for prenatal exposure to lead, and Brazelton neonatal behavioral assessment scale (NBAS), as an indicator for effect, were determined in 86 neonates in Gumi, Kyungpook, Korea. The blood levels were measured by graphite furnace atomic absorption spectrophotometer. Development was assessed by NBAS at birth in 86 neonates and at I month in 55 neonates. Results: The mean cord blood lead levels of the 86 and 55 neonates were 3.90±0.7I μg/dI (range 2.24 - 5.39 μg/dl) and 3.88±0.70 μg/dl (range 2.24∼5.03 μg/dl), respectively. We used the median value of 4 μg/dl to divide into low- and high- lead level groups. There was a significant difference in the peak of excitement at birth, and in the animate visual, inanimate visual, inanimate auditory, activity level, peak of excitement, and liability of states at one month, between the two groups. For cluster scores, motor system and state organization scores showed significant differences between the two groups. For adjusting the potential confounding effect of intial difference, differences of the scores between the two groups at one month were analysed with ANCOVA. The results of ANCOVA showed the significant difference between the two groups. Conclusions: The findings suggest that prenatal low-level lead exposure, even lower than 10 μg/dl, might affect the neonatal neurobehavioral development.

Methanol-Gasoline 混合燃料使用機關의 點火時期에 代한 性能考察

韓炳祜,金春中 영남이공대학 1980 論文集 Vol.9 No.-

In this paper, we were studied engine performance, heat dissipations and mechanical efficiency by means of measuring fuel consumption, engine torque and cooling water consumption of engine used methanol gasoline fuel blends according to spark timing advance. And we were measured Carbon Monoxide (CO) and Hydro Carbon (tIC) of engine. Engine spark timing advance angle were changed from 10° to 60° at 10° interval, and methanol gasoline fuel blends were from 10% to 50% at 10% interval. From the above investigated, the results were abtained as following. 1. Fuel consumption ratio become minimum and brake horse power become maximum at point of spark advance nearby before 'fop Dead Center 30°. 2. Mechanical efficiency and quantity of heat dissipation become maximum at point of spark advance nearby before Top Dead Center 40°. 3. As methanol contend in fuel increased, CO emission decreased, and HC emission is slowness to methanol gasoline mixture ratio 30%.

산화스트레스와 항산화제

이병근,정동춘,전태원,정성태,정덕조 師範大學 體育硏究所 1998 서울大學校 體育硏究所論集 Vol.19 No.2

Performance of strenuous physical activity can increase oxygen consumption by 10 to 15-fold over rest to meet energy demands. The resulting elevated oxygen consumption produces an "oxidative stress" that leads to the generation of free radicals and lipid peroxidation. A defense system of free radical scavengers minimizes these dangerous radicals. Indirect measurements of free radicals generated during exercise include assessing products of lipid peroxidation that appear in the blood (e.g., malondialdehyde and conjugated dienes) or expired in the breath (pentane). Changes in antioxidant scavengers and associated enzymes (e.g., glutathione, tocopherol, glutathione peroxidase) also provide clues about demands on the defense system. Physical training has been shown to result in an augmented antioxidant system and a reduction in lipid peroxidation. In recent years, much attention has been paid to the role antioxidants play in physical activity and physical performance. This attention is largely focused on the increase in free radicals generated during strenuous exercise. As oxygen consumption, and hence oxidative stress, is increased, free radicals are produced. Studies have reported that antioxidant supplementation can reduce evidence of exercise induced lipid perozidation. It has been suggested that those who engage in chronic physical activity, placing a constant oxidative stress on the muscles and other cells, may require additional antioxidants to help them recover from exercise. Other than their role in reducing tissue damage, the data are equivocal with respect to whether antioxidants will directly enhance physical performance. Antioxidant supplementation may be prepared to handle an sudden increase in oxidative stress. Studies have shown increases in oxidative stress during performance of strenuous exercise and then supplementation would reduce this stress. The effects of antioxidant supplementation on physical performance are very affirmative.

전기로 분진에서 납의 휘발반응에 대한 속도론적 연구

김병수,유재민,이재천,남철우,윤정모 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.4

"he removal of lead from electric arc furnace (EAF) dust is important in the process for recovering zinc by a reduction-volatilization method. In this study, experiments on kinetics of the volatilization reaction of lead by chlorine components as NaCl and KCl contained in the EAF dust were carried out in the temperature range of 973 to 1223 K under an air atmosphere using a weight-loss technique. As a result, the volatilization ratio of lead was about 99.0% at the temperature of 1223 K and the reaction time of 180 min. Jander equation was found to fit well the volatilization reaction rate over the entire temperature range. The volatilization reaction of lead is rate controlled by solid-solid diffusion. An activation energy of 175 kJ/mol(41.8 kcal/mol) was obtained. (Received January 8, 2004)