반정량 식품섭취빈도조사의 응답에 관한 인지면접연구

이경실(Lee Gyeong Sil1),백희영(Paik Hee Young),이명선(Yi Myung Sun),정효지(Joung Hyo Jee) 韓國營養學會 2007 Journal of Nutrition and Health Vol.40 No.6

The purpose of this research was to understand how individuals reflect on the frequency and quantity of foods that they consume. Participants selected 5 males and 15 females aged 30 years or older were first interviewed on the frequency of their food consumption. Then based on this data, they were given a cognitive interview using the method of verbal proving. The individual cognitive interviews were recorded with consent while being conducted after complete approval by the Seoul National University Institution Review Board. The recorded material was evaluated using a thematic analysis after transcribing them into text. By analyzing stages of reflection, the major barriers to make the device difficult are revealed: 1) More difficulty in remembering events over the course of a full year due to diversification in the types of food that people consume 2) difficulty calculating the average for seasonal foods 3) difficulty estimating the amount of consumption from the photos presented 4) difficulty estimating amount of consumption from the quantity presented 5) difficulty processing foods that people think are healthy and foods are unhealthy simultaneously 6) difficulty having to consider foods where target food goes in as an ingredient; 7) difficulties arising from having to increase frequency when the amount consumed is higher than the quantity that is presented 8) difficulty having to combine the frequency and quantity of each food item when numerous foods are clustered into one category. These findings show that the less participants were involved in cooking, the more diverse their eating habits were, and the more they tried to adhere to rules of filling out the questionnaire, the more it was difficult for them to come up with an answer to the question being asked. It therefore seems necessary to construct a Food Frequency questionnaire that is attentive to these problems that arise from the recall stages.

학교급식 식자재 공급업체 선정요인의 우선순위에 관한 연구

박명주,김석환,이정실 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.4

The purpose of this study is to examine how nutritionists, principals and parents evaluated the importance and priorities of different selection factors for food materials suppliers in an attempt to suggest how to ensure the best supplier choice, since the selection of the best supplier was mandatory for the successful TQM of school food services. This study especially aims to develop priority alternatives based on relative rather than absolute assignments on selection of suppliers for school food service materials. To apply AHP, the selection factors of a food materials suppliers were grouped into five categories, which included quality, service, reliability, hygiene and price. And the five categories involved 28 elements. As the result, quality was considered most crucial on the whole, followed by service, reliability, hygiene and price; and food labeling in the category of quality evaluated as that of first priority in the totality evaluation elements.

Secretion of EGF-Like Domain of Heregulin${\beta}$ Promotes Axonal Growth and Functional Recovery of Injured Sciatic Nerve

Joung, In-Sil,Yoo, Min-Joo,Woo, Ji-Hyoun,Chang, Chi-Young,Heo, Hwon,KimKwon, Yun-Hee Korean Society for Molecular and Cellular Biology 2010 Molecules and cells Vol.30 No.5

Neuregulin 1 (NRG1) and epidermal growth factor receptor (ErbB) signaling pathways control Schwann cells during axonal regeneration in an injured peripheral nervous system. We investigated whether a persistent supply of recombinant NRG1 to the injury site could improve axonal growth and recovery of sensory and motor functions in rats during nerve regeneration. We generated a recombinant adenovirus expressing a secreted form of EGF-like domain from Heregulin${\beta}$ (sHRG${\beta}$E-Ad). This virus, sHRG${\beta}$EAd allowed for the secretion of 30-50 ng of small sHRG${\beta}$E peptides per $10^{7-8}$ virus particle outside cells and was able to phosphorylate ErbB receptors. Transduction of the concentrated sHRG${\beta}$E-Ad into an axotomy model of sciatic nerve damage caused an effective promotion of nerve regeneration, as shown by histological features of the axons and Schwann cells, as well as increased expression of neurofilaments, GAP43 and S100 in the distal stump of the injury site. This result is consistent with longer axon lengths and thicker calibers observed in the sHRG${\beta}$E-Ad treated animals. Furthermore, sensory and motor functions were significantly improved in sHRG${\beta}$E-Ad treated animals when evaluated by a behavioral test. These results suggest a therapeutic potential for sHRG${\beta}$E-Ad in treatment of peripheral nerve injury.

Functional Implications in Apoptosis by Interferon Inducible Gene Product 1-8D, the Binding Protein to Adenovirus Preterminal Protein

Joung, In-Sil,Angeletti, Peter C.,Engler, Jeffrey A. The Microbiological Society of Korea 2003 The journal of microbiology Vol.41 No.4

Adenovirus (Ad) precursor to the terminal protein (pTP) plays an essential roles in the viral DNA replication. Ad pTP serves as a primer for the synthesis of a new DNA strand during the initiation step of replication. In addition, Ad pTP forms organized spherical replication foci on the nuclear matrix (NM) and anchors the viral genome to the NM. Here we identified the interferon inducible gene product 1-8D (Inid) as a pTP binding protein by using a two-hybrid screen of a HeLa cDNA library. Of the clones obtained in this assay, nine were identical to the Inid, a 13-kDa polypeptide that shares homology with genes 1-8U and Leu-13/9-27, most of which have little known functions. The entire open reading frame (ORF) of Inid was cloned into the tetracycline inducible expression vector in order to determine the biological functions related with adenoviral infection. When Inid was introduced to the cells along with adenoviruses, fifty to sixty percent of Ad-infected cells expressing Inid had rounded morphology, which was suggestive of apoptosis. Results from the terminal deoxynucleotidyl transferase (TdT) and DNA fragmentation assays confirmed that Inid induces apoptosis in Ad-infected or in uninfected cells. The Inid binding to pTP may target the cell for apoptotic destruction as a host defense mechanism against the viral infection.

Ceramide에 의한 신경세포 사멸과정에서 p62의 역할

정인실(Joung, In-Sil) 한국산학기술학회 2009 한국산학기술학회논문지 Vol.10 No.3

p62는 산화스트레스가 주요 원인 중 하나인 퇴행성 뇌질환과 연관된 엉긴 물질(aggregate)의 주요 구성성분이다. 퇴행성 뇌질환과 관련된 것으로 알려진 hydroxydopamine이나 C₂-ceramide를 신경모세포종 세포주인 SH-SY5Y에 처리하였을 때 p62의 발현이 유도되며 시간이 지날수록 그 양이 증가되었다. 또한 p62를 과발현시키면 ceramide에 의한 SH-SY5Y 세포의 사멸이 지연되었다. 이 과정에서 p62는 시간이 경과됨에 따라 침전화되며 절단되었다. 이 결과로 p62의 신경보호효과와 여러 종류의 퇴행성 뇌질환에서 p62가 엉긴 물질에서 발견되는 이유를 추측할 수 있다. p62 is a key component of protein aggregates found in brains of neurodegenerative diseases in which oxidative stress is involved in the pathogenesis. p62 was induced in SH-SY5Y, a neuroblastoma cell line, by hydroxydopamine or C₂-ceramide known to be related to neurodegenerative diseases. The over-expression of p62 showed the neuroprotective effect against the ceramide induced cell death. In addition, p62 became insoluble and cleaved forms as time proceeded after the ceramide treatment, suggesting the mechanism by which p62 is associated with aggregates in neurodegenerative diseases.

서비스 기업에서의 관계혜택이 관계몰입과 관계지속의도에 미치는 영향 -서비스 업종별 비교-

이정실 ( Joung Sil Lee ),허범영 ( Byum Young He ),홍순복 ( Soon Bok Hong ),임채관 ( Chae Kwan Lim ),강경수 ( Kyoung Soo Kang ),조윤주 ( Youn Joo Cho ) 관광경영학회 2012 관광경영연구 Vol.51 No.-

This study is to verify the structural relationship among 3 typical factor relational benefits, relational commitment, and relational continuance intention in service corporation. To test each measures; predictive utility in this context with AMOS. Sampling in this study is limited to the department store, beauty parlor, dental clinic and hotel restaurant in Busan, South Korea. The responders included 632. Data were analyzed by frequency, factor analysis, and AMOS. As the results, social benefit is major to influence on the relational commitment and relational continuance intention. Confidence benefit is major to influence on the relational continuance intention, while isn`t major determinant to influence on the relational commitment. Special treatment benefit is major to influence on the relational commitment, while isn`t major determinant to influence on the relational continuance intention. Social benefit is major to influence on the relational commitment in all of 4 service corporations. While confidence benefit isn`t major determinant to influence on the relational commitment in all of 4 service corporations. Special treatment benefits is major to influence on the relational commitment in beauty parlor, dental clinic and hotel restaurant.

연구논문 : 서비스접점에서 고객 평가요인이 감정적 반응과 행동의도에 미치는 영향 -부산지역 특급호텔을 중심으로-

이정실 ( Joung Sil Lee ) 대한관광경영학회 2007 觀光硏究 Vol.22 No.2

AHP를 이용한 호텔 레스토랑 선택속성의 우선순위분석

이정실 ( Joung Sil Lee ) 대한관광경영학회 2006 觀光硏究 Vol.21 No.3

Kasavana & Smith의 메뉴분석방식과 Pavesic의 메뉴분석방식의 비교연구

이정실 ( Joung Sil Lee ) 대한관광경영학회 2005 觀光硏究 Vol.20 No.1

고객가치, 고객만족과 충성도의 관계에서 전환장벽의 조절효과

이정실(Joung Sil Lee) 한국관광연구학회 2009 관광연구저널 Vol.23 No.2

Service marketing research has traditionally focused on the relationship between service quality and satisfaction, while assuming that the relationship between satisfaction and loyalty is well understood. However, recently many scholars argue that guest satisfaction alone can not explain loyalty fully, and suggest the need for more extensive researches investigating the determinants of loyalty. Drawing from social theory, this study identifies guest value, and switching barriers. So, this study aims to investigate the adjustment effect of switching barriers on relationships guest value, guest satisfaction and loyalty. The detailed factors regarding switching barriers are classified based on the related literatures. Furthermore, the hierarchial regression analysis is used to analyze the extent to which the factors affect loyalty. The result are as follows; First, among the factors of switching barrier, switching costs, interpersonal relationship and attractiveness of alternatives are key factors in determining loyalty. Second, switching costs, interpersonal relationship, and service recovery have an adjustment effect between guest value and loyalty. Third, switching costs, interpersonal relationship, and service recovery also have an adjustment effect between guest satisfaction and loyalty.