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      • 철도시스템분야 실무적용을 위한 RAM Guidance 개발에 관한 연구

        이중섭(Joong Sub31 Lee),백영구(Young Goo Baek),이진(Jin Lee),한미정(Mi Jung Han),김성환(Sung Hwan Kim) 한국철도학회 2015 한국철도학회 학술발표대회논문집 Vol.2015 No.10

        철도시스템 기술 고도화 및 복잡성의 증대와 더불어 발주기관으로부터 시스템의 성능보증과 안전성 확보가 요구되고 있는 실정이다. 또한 국내 철도안전법 강화로 인하여 시스템 보증활동의 중요성이 증가되고 있다. 본 논문에서는 국제철도관련 규격을 바탕으로 철도시스템의 RAM 업무에 대한 절차를 정의하고, 해당 철도 프로젝트에서 RAM 업무를 원활히 수행할 수 있도록 관련된 국제 규격 및 유사시스템 적용 사례에 기반하여 철도시스템 개발 특성을 고려한 RAM 업무 수행 지침(Guidance)을 개발하였다. Performance and safety assurances for the railway system are required by the client because of the high degree of technology and increased complexity. In addition, as a result of reinforced domestic railway safety laws, the importance of system assurance activity has been growing steadily. This paper defines the task of the RAM process based on international railway industry standards for RAMS engineers to work efficiently and develops the RAM guidance considering the railway system characteristics based on domestic standards and application cases of railway systems.

      • KCI등재

        시스템분석의 주요변수와 시스템성과와의 상관관계 연구 : 분석기간, 사용자참여 및 통제조직을 중심으로

        장시영,최중섭 한국경영과학회 1991 經營 科學 Vol.8 No.2

        This study investigates the relationship between some control factors of systems analysis and information systems effectiveness. For this purpose, a research model is set up that consists of three independent variables (duration of systems analysis, user involvement, and control organization/mechanism) and a dependent variable (user satisfaction). Data were gathered from thirty-two industry firms in Korea. The results of data analysis indicate that only user involvement is significantly related to the dependent variable. Among independent variables, the existence of the sign-off procedure and auditing organization is associated with the relative duration of systems analysis. Discussions of the results are presented, followed by the suggestions for future research.

      • BA, NAA, 2,4-D 및 배지의 무기물 농도가 포도의 기내 생장에 미치는 영향

        金善圭,全盛皓,李重燮 충북대학교 농업과학기술연구소 1997 農業科學硏究 Vol.14 No.-

        Shoot tip and node segments derived from cuttings of two grape cultivars (Aramon, Aligote) were cultured in vitro on full - and one half strength MS media supplemented with BA, NAA, and 2,4-D alone and in combination, and the growth was investigated. Full strength, shoot tip, and NAA enhanced the shoot growth. BA alone and/or in combination with NAA was favorable for shoot multiplication regardless of media strength and bud position. Varietal differences were recognized in callus formation in favor of Aramon, and all growth regu-lators, especially BA+ NAA+2,4-D, were effective for callus formation in Aramon. Bud position ef-fect was negligible but half stremgth media was more effective. In Aligote, 2,4-D was most effective for callus formation regardless of media strength.

      • KCI등재

        바른체형운동 지도가 정신장애인의 우울감 및 폐활량에 미치는 효과

        우경희(Kyung-Hee Woo),양정옥(Jeong-Ok Yang),이중숙(Joong-Sook Lee),이범진(Bom-Jin Lee),김의숙(Eui-Suk Kim),정숙희(Sook-Hee Jung),곽이섭(Yi-Sub Kwak) 한국생명과학회 2016 생명과학회지 Vol.26 No.10

        본 연구는 바른체형운동 프로그램이 정신장애인의 폐활량 및 우울감에 미치는 영향을 알아보고자 경북 P시에 거주하고 정신장애 판정을 받았으며 정신재활프로그램에 참여하는 정신장애인을 대상으로 실시하였다. 참여한 피험자에게 연구목적과 내용을 설명하였고, 연구 참가동의서를 받은 19명을 최종 선정하여 10명은 운동군, 9명은 통제군으로 분류하여 12주간 바른체형운동 프로그램을 실시하였고, 연구결과는 다음과 같다. 우선 폐활량의 변화를 살펴본 결과 PEF (최대호기속도)와 FEV1/FVC (1초간 노력성 호기량의 노력성 폐활량에 대한 비)가 바른체형운동 적용 후에 증가하여 호기기능이 유의하게 향상됨을 확인하였다. 또한, 바른체형운동 프로그램 참여에 따른 운동군의 우울감의 변화는 통계적으로 유의한 차이는 나타나지 않았으나 우울정도의 감소폭이 통제군보다 운동군에서 훨씬 크게 나타나 바른체형운동이 정신장애인의 우울감 정도의 감소에 긍정적인 변화를 나타냈다고 할 수 있다. 그리고 본 연구에서는 프로그램 참가자들의 특수성으로 인한 표본 수의 한계로 인해 통계적 검증의 한계가 명확히 존재함을 고려하여 참여자들의 주관적 경험을 심층적으로 이해하는 것을 목적으로 한 질적분석(qualitative research)을 병행하여 실시하였다. 프로그램 참가자 중 동의하는 사람에 한해 심층적 면담을 실시하였으며 이를 통해 참여자들이 표현하는 내용의 의미단위를 검토하여 분류하고 세분화하는 작업을 통해 주제분석(thematic analysis)을 실시한 결과, 전반적으로 바른체형운동 프로그램에 참여한 정신장애인들의 우울감 정도가 줄어든 것을 알 수 있었다. 우울감의 변화과정은 ‘변화의 시작’, ‘프로그램에 대한 흥미’, ‘신체적 건강의 필요성에 대한 인식’, ’신체적 건강증진’, ’신체적 기능의 회복’, ’부정적인 습관(자세)의 변화’, ’우울감의 감소’, ’할 수 있다는 자신감’, ’미래에 대한 희망’과 같은 3개의 주제와 6개의 하위 주제로 나타났다. 따라서 바른체형운동이 정신장애인들의 신체적 건강증진을 위해 심폐지구력을 높여 신체적 건강증진을 도모할 뿐 아니라 더 나아가 정신적 우울감의 감소에도 효과성을 높여 정신적 건강증진에도 도움을 줄 수 있는 프로그램으로 정신장애인의 삶의 질 증진을 위해서는 보급이 반드시 필요할 것으로 사료된다. The purpose of this study was to investigate the effects of the regular Upright Body Type Excercise on posture, muscle strength of leg, lung capacity and depression of people with mental illness. The subjects of this study were recruited from B mental health center (5 years and more mental illness patients, n=19) located in P city. For the exercise group, They were carried out the Upright Body Type Excercise Program during 8 weeks (60 min/time, 3 times/week). They were randomly divided into two groups. Exercise group (n=10) and Control group (n=9). And also, they were agreed with consent forms before the experiments. Research results were as follows. Through the upper body type exercise, there was significantly difference in PEF and FEV1/FVC in the trained group. And also, there was much improved in depression level in the trained group. The change of melancholy feeling before and after the program was not statistically significant. However, because of limitations of sampling size due to the peculiarities of the program participants, in consideration of the limit of statistical validation exists clearly, intended to better understand the subjective experience of attendees, qualitative analyzing(qualitative research) was carried out in parallel. It was conducted a deep interview only person accepted among program participants, thematic analysis, subject analysis tasks to be subdivided by classifying by considering the semantic units of what participants expressed, was thus carried out. It found that the degree of melancholy feeling of mental disorders who participated in the Upright Body Typed Exercise Program was reduced. The course of the experience of change in depression appered the three subjects and six sub-themes such as “the start of the change”, “interest of the program”, “recognition of the need of the body`s health”, “physical health promotion”, “recovery of physical function”, “negative change of habits (attitude)”, “reduction of sense of depression”, “confidence that it is possible to”, “hope for the future”. Therefore, upper body type exercise is much helpful in lung capacity and mental health of people with mental illness. So, this type of exercise mostly needed in the people with mental illness group than the other group for the quality of life.

      • Porous Zn<sub>2</sub>GeO<sub>4</sub> nanowires with uniform carbon-buffer layer for lithium-ion battery anodes with long cycle life

        Kim, Jung Sub,Kim, A-Young,Byeon, Young Woon,Ahn, Jae Pyoung,Byun, Dongjin,Lee, Joong Kee Elsevier 2016 ELECTROCHIMICA ACTA Vol.195 No.-

        <P><B>Abstract</B></P> <P>Germanium-based multimetallic-oxide materials have attracted significant attention as high-capacity anodes for next generation lithium-ion batteries (LIBs). However, they suffer from poor cyclic stability due to extreme volume expansion and reduced electrical conductivity after repeated cycles. To circumvent these issues, we propose that Ge-based multimetallic-oxide nanowires can be synthesized with electrically conductive carbon to significantly enhance the cyclic stability of the Ge-based anodes. We prepare conformal-carbon-coated Zn<SUB>2</SUB>GeO<SUB>4</SUB> nanowires (NWs) using a microwave-induced hydrothermal method with subsequent thermal decomposition. The obtained carbon-coated Zn<SUB>2</SUB>GeO<SUB>4</SUB>-NW anode exhibits a discharge capacity of 485 mAh/g and a Coulombic efficiency (CE) of 98.4% after 900 cycles at 0.6C. Furthermore, these anodes exhibit outstanding rate-capability characteristics, even with an increased C-rate of 17.7C. This excellent electrochemical performance can be ascribed to the improved electron and ion transport provided and the structurally reinforced conductive layer comprising a conformal carbon layer. Therefore, it is expected that our approach can also be applied to other multimetallic-oxide materials, resulting in large, reversible capacities; excellent cyclic stabilities; and good rate capabilities for high-performance LIBs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Carbon coated Zn<SUB>2</SUB>GeO<SUB>4</SUB> nanowires were synthesized using microwave hydrothermal method. </LI> <LI> The obtained electrode exhibits outstanding rate-capability and cycling stability. </LI> <LI> Uniform carbon layer plays an important role in minimizing the volume change. </LI> <LI> In situ SEM images show reduced volume change in lateral and longitudinal direction. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Electrochemical performance can be ascribed to the improved electron and ion transport provided and the structurally reinforced conductive carbon layer.</P> <P>[DISPLAY OMISSION]</P>

      • SCIESCOPUSKCI등재

        Regulation of toll-like receptors expression in muscle cells by exercise-induced stress

        Park, Jeong-Woong,Kim, Kyung-Hwan,Choi, Joong-Kook,Park, Tae Sub,Song, Ki-Duk,Cho, Byung-Wook Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.10

        Objective: This study investigates the expression patterns of toll-like receptors (TLRs) and intracellular mediators in horse muscle cells after exercise, and the relationship between TLRS expression in stressed horse muscle cells and immune cell migration toward them. Methods: The expression patterns of the TLRs (TLR2, TLR4, and TLR8) and downstream signaling pathway-related genes (myeloid differentiation primary response 88 [MYD88]; activating transcription factor 3 [ATF3]) are examined in horse tissues, and horse peripheral blood mononuclear cells (PBMCs), polymorphonuclear cells (PMNs) and muscles in response to exercise, using the quantitative reverse transcription-polymerase chain reaction (qPCR). Expressions of chemokine receptor genes, i.e., C-X-C motif chemokine receptor 2 (CXCR2) and C-C motif chemokine receptor 5 (CCR5), are studied in PBMCs and PMNs. A horse muscle cell line is developed by transfecting SV-T antigen into fetal muscle cells, followed by examination of muscle-specific genes. Horse muscle cells are treated with stressors, i.e., cortisol, hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), and heat, to mimic stress conditions in vitro, and the expression of TLR4 and TLR8 are examined in stressed muscle cells, in addition to migration activity of PBMCs toward stressed muscle cells. Results: The qPCR revealed that TLR4 message was expressed in cerebrum, cerebellum, thymus, lung, liver, kidney, and muscle, whereas TLR8 expressed in thymus, lung, and kidney, while TLR2 expressed in thymus, lung, and kidney. Expressions of TLRs, i.e., TLR4 and TLR8, and mediators, i.e., MYD88 and ATF3, were upregulated in muscle, PBMCs and PMNs in response to exercise. Expressions of CXCR2 and CCR5 were also upregulated in PBMCs and PMNs after exercise. In the muscle cell line, TLR4 and TLR8 expressions were upregulated when cells were treated with stressors such as cortisol, H<sub>2</sub>O<sub>2</sub>, and heat. Migration of PBMCs toward stressed muscle cells was increased by exercise and oxidative stresses, and combinations of these. Treatment with methylsulfonylmethane (MSM), an antioxidant on stressed muscle cells, reduced migration of PBMCs toward stressed muscle cells. Conclusion: In this study, we have successfully cultured horse skeletal muscle cells, isolated horse PBMCs, and established an in vitro system for studying stress-related gene expressions and function. Expression of TLR4, TLR8, CXCR2, and CCR5 in horse muscle cells was higher in response to stressors such as cortisol, H<sub>2</sub>O<sub>2</sub>, and heat, or combinations of these. In addition, migration of PBMCs toward muscle cells was increased when muscle cells were under stress, but inhibition of reactive oxygen species by MSM modulated migratory activity of PBMCs to stressed muscle cells. Further study is necessary to investigate the biological function(s) of the TLR gene family in horse muscle cells.

      • Laparoscopic Para-aortic Lymphadenectomy (LPAL): Standard Surgical Boundary and Technique

        ( Joong Sub Choi ),( Jaeman Bae ),( Won Moo Lee ),( Un Suk Jung ),( Jeong Min Eom ),( A Ra Koh ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-

        목적: Teach a new procedure. 방법: We conducted a retrospective chart review of 324 patients with gynecologic malignancies who had undergone LPAL by a single surgical team between November 2003 and May 2015. 결과: Three hundred seventeen patients underwent LPAL as part of their staging, restaging or debulking surgery. Seven patients with isolated para-aortic lymph node recurrence underwent a repeat LPAL. The median age and BMI were 54 years (range 28-81 years) and 26.0 kg/m2 (range 20.3 -37.2 kg/m2), respectively. The median operating time was 60 minutes (range 24-135 minutes), and the median number of harvested para-aortic lymph nodes was 12 (range 6-49). There were eleven cases of complications: five of major vessel injuries (three IVC, one aorta, and one common iliac vein), two lymphocysts, two cases of chylous ascites, a cisterna chyli rupture, and one case of ureteric injury. There were two conversions to laparotomy: one left common iliac vein laceration that needed to be repaired and removal of an enlarged para-aortic lymph node completely. 결론: It is feasible and efficient to perform LPAL to the left renal vein level for women with gynecologic malignancies by well-trained gynecologic oncology surgeon according to our suggested standard surgical boundary.

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