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      • 성인의 경부 전면 중앙부위에서 발생한 기형종 1예

        최월용,정효진,채종인,하태인,정상렬,이광재,채병도,최영식 고신대학교 의학부 2004 高神大學校 醫學部 論文集 Vol.19 No.1

        Teratomas are embryonal neoplasms that show characteristics of three germ cell layers(ectoderm, mesoderm, and endoderm). They are distributed in the following regions: sacrococcygeal(57%), gonadal(29%), mediastinal(7%), cervical(3%), retroperitoneal(4%), and intracranial(3%) regions. Non-gonadal treatomas present in infancy whereas gonadal are seen in adolescence. Especially, teratomas that occurred in midline neck of adult are very rare and are confused with thyroglossal duct cysts, cystic hygromas, and thyroid tumors. We report, along with the review of appropriate literature, a case of histopathologically confirmed benign teratoma in the midline neck of a 33 years old woman.

      • KCI등재
      • 담즙정체성 간염의 임상적 양상

        최선택,은종렬,임상우,김봉준,이헌주,구미진,최준혁 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

        Background: Cholestatic hepatitis is failure of bile to reach the duodenum with hepatocellular damage and no demonstrable obstruction of the major bile ducts. The prognosis is usually good with recovery in less than 4 weeks after withdrawal of the offending drug. However, a prolonged course lasting over 3 months is possible and, in rare cases, progression to ductopenia with development of a vanishing bile duct syndrome occurs. A differential diagnosis with other causes of Chronic liver disease is needed. Materials and Methods: From January 1991 through Jaunary 2000, 14 patients diagnosed as cholestatic hepatitis by liver biopsy were inclouded. The possible causative drug, clinical features, laboatory findings, and progression of cholestatic hepatitis were evaluated. The semiquantitative study of liver lesions was performed by two independent observers. Results: Causes of cholestatic hepatitis are 5 cases of oriental medicine, 3 cases of anti-tuberculosis medication, 1 case of ticlopidine and antibiotics and 4 cases of unknown causes. The clinical features of cholestatic hepatitis were jaundice, itching, urine color change, and general weakness. During 6 to 30 months, LFT of 5 patients showed prolonged elevation. Elevated total cholesterol ≥250 mg/dL in 6 patients, pheripheral blood eosinophilia in 5 patients, auto-antibody positive in 6 patients were observed respectively. The biopsies showed intralobular bilirubinostasis with a mixed portal inflammatory infiltration. Conclusion: In cholestatic hepatitis. durations of abnormal LFT are variable regardless of causative drugs. If cholestatic hepatitis progresses toward chronic course, viral hepatitis, primary biliary cirrhosis, and autoimmune hepatitis should be differentially diagnosed and sequential liver biopsies are needed.

      • KCI등재후보

        VDT작업별 정신사회적 스트레스와 근골격계 장애에 관한 연구

        백남종,강종두,주영수,배인근,권호장,박종만,조수헌,김돈규,김재용,최홍렬 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

        It has been hypothesized that jobs that have both high psychological demands and low decision latitude("job strain") can lead to musculoskeletal disorder. The objective of this study was to test whether job strain was correlated with the presence of work-related musculoskeletal disorder, especially myofascial pain syndrome(MPS). Information on demographic factors, confounders such as household load and taking care of children or not, and scores for decision latitude, job demand, and social support was obtained by self-administered questionnaire, which had been developed in Korean language, by adopting NIOSH instrument and Extended Karasek Model(16 items). All subjects were also examined by rehabilitation medicine specialists for musculoskeletal disorders. Subjects(n=370) could be categorized into 4 groups, these were, housewives(n=89), shipyard CAD workers(n=89), general female workers(n=79; nurses, insurance counselors, public officials, clerks, etc), and telephone directory assistance operators(n=113). Results from univariate analyses indicated that all demographic factors, all confounders, scores for decision latitude and social support were not associated with the risk of musculoskeletal disorder. However, score for job demand was higher in musculoskeletal disorder cases than others. In subgroup analysis, this association was convinced again, in telephone directory assistance operators. Job strain model showed that the group of telephone directory assistance operators was high-stain group, and OR of musculo skeletal disorder was 2.446(95% C. I. : 1.174, 5.096), when comparing this with the low strain group. In conclusion, job strain is a risk factor for work-related musculoskeletal disorder.

      • 영주지방에 있어서 봉군의 실내월동 시험

        이동률,이종원,이석건,최광수 慶北大學校農業科學技術硏究所 2001 慶北大農學誌 Vol.19 No.-

        The studies was conducted to establish the indoor overwintering methods for productive honeybee colonies in the wintering chamber which provides satisfactory inside temperature ranging 2∼9。C and ventilation for the wintering honeybee colonies in Korea. Mortality of the indoor wintered honeybee colonies was 6.3∼7.1% during the winter season of 1997-1998 and 5∼10% during the winter season 1998∼1999. The decreased rates of colony weights during the wintering season were 10.6∼10.7% in the strong colonies and 10.2∼11.7% in the weak colonies. The increased rates of colony population overwintered in the chamber were 136.1∼142.3% in the strong colonies and 128∼136.5% in the weak colonies.

      • KCI등재

        Chlorhexidine 처리가 상아질 접착제의 미세인장결합강도에 미치는 영향

        오은화,최경규,김종률,박상진 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.2

        본 연구는 상아질 혼성층의 교원섬유를 가수분해하는 효소인 MMPs (Matrix metalloproteinses) 억제제로 알려진 chlorhexidine (CHX)을 적용 후 결합강도를 측정하였으며, 이를 각각 열순환 처리 후 결합강도를 측정하였다. 또한 주사전자현미경으로 접착계면메서의 파괴 양상을 비교 분석하였다. 우식이 없는 발거한 32 개의 제 3 대구치의 교합면 상아질을 노출시키고 GI그룹에서는 dentin conditioner를 처리 후 2% chlorhexidine을 적용시키고, 산부식 접착제 그룹에서는 인산 산부식을 시행하고 2 % chlorhexidine을 적용 후 3단계 산부식형 상아질 접착제 (Scotchbond Multipurpose, SM), 2단계 산부식형 상아질 접착제 (Single Bond, SB)를 도포하고, 자가부식 접착제 그룹에서는 2 % chlorhexidine 적용 후 자가부식 상아질 접착제 (Clearfil Tri-S, TS)를 도포한다. 이후 복합 레진 (Z-250)과 GI (Fuji-II LC)를 충전한 시편을 1 ㎟의 단면을 갖는 beam으로 제작하여 열순환 하지 않거나, 10,000 회 열순환 (5 ~ 55 ℃)하였다. Universal testing machine (EZ-test: Shimadzu, Japan)에서 cross head speed 1 mm/min로 인장력을 가하여 , 미세인장결합강도를 측정하였다. 실험 결과는 유의수준 0.05 1evel에서 two-way ANOVA를 이용하여 통계분석하였다. 그 후 파절된 시편의 파괴 양상을 현미경 (SEM)으로 관찰하여 다음과 같은 갈론을 얻었다; 1. 2 % CHX을 적용한 모든 실험군에서 상아질과의 미세인장결합강도가 증가하였고, 열순환은 상아질과의 미세인장 결합강도를 감소시켰다 (P>0.05). 2. CHX 적용 후 열순환 한 군은 CHX을 적용하지 않고 열순환한 군에 비하여, 상아질과의 미세인장결합강도가 높았으며 , 특히 GI와 TS군에서 유의한 차이를 나타내었다 (P<0.05). 3. 파괴 양상 분석 결과, 혼성층에서의 접착성 파괴를 보이며, CHX을 적용하면 혼성층 기저부에서 상부로 파괴 부위가 옮겨가는 양상을 나타내었다. 이상의 연구 결과를 토대로, MMPs 억제제인 2 % CHX은 글래스 아이오노머 시멘트와 상아질 접착제의 초기 미세인장결합강도에는 영향을 미치지 않으며 ,CHX 적용이 접착 내구성을 유지하는데 도움이 되었다. The purpose of this study was to evaluate the effect of chlorhexidine (CHX) on microtensile bond strength (μTBS) of dentin bonding systems. Dentin collagenolytic and gelatinolytic activities can be suppressed by protease inhibitors. indicating that MMPs (Matrix metalloproteinases) inhibition could be beneficial in the preservation of hybrid layers. Chlorhexidine (CHX) is known as an inhibitor of MMPs activity in vitro. The experiment was proceeded as follows : At first, flat occlusal surfaces were prepared on mid-coronal dentin of extracted third molars. GI(Glass lonomer) group was treated with dentin conditioner, and then, applied with 2 % CHX. Both SM (Scotchbond Multipurpose) and SB (Single Bond) group were applied with CHX after acid-etched with 37% phosphoric acid. TS (Clearfil Tri-S) group was applied with CHX, and then, with adhesives. Hybrid composite Z-250 and resin-modified glass ionomer Fuji-II LC was built up on experimental dentin surfaces. Half of them were subjected to 10,000 thermocycle, while the others were tested immediately. With the resulting data, statistically two-way ANOVA was performed to assess the μTBS before and after thermocycling and the effect of CHX. All statistical tests were carried out at the 95 % level of confidence. The failure mode of the testing samples was observed under a scanning electron microscopy (SEM). Within limited results, the results of this study were as follows; 1. In all experimental groups applied with 2 % chlorhexidine, the microtensile bond strength increased, and thermocycling decreased the microtensile bond strength (P > 0.05). 2. Compared to the thermocycling groups without chlorhexidine, those with both thermocycling and chlorhexidine showed higher microtensile bond strength, and there was significant difference especially in GI and TS groups.

      • KCI등재후보

        일부 조선업 근로자의 직업성 요통 발생실태 및 위험요인에 관한 연구

        고상백,김형식,최홍렬,김지희,송인혁,박준한,박종구,장세진,차봉석 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

        목적 : 이 연구에서는 한 사업장의 동일한 코호트내에서 직업성 요통의 발생 및 발생원인에 대해 조사하고자 하였다. 방법 : 연구대상은 1995년 12월 현재 한 조선업체에 종사하는 근로자 중에서 1995년 12월 31일 까지 요통이 이미 발생한 근로자와 1995년 당시 검진 미수검자를 제외한 9,784명을 연구대상으로 하였다. 요통 발생군은 1996년부터 1998년까지 3년간 추적 관찰하여 요통으로 4일 이상 통원 또는 입원치료를 받은 근로자로 하였다. 발생률은 요통발생 당시 연도를 기준으로 하여 해당 연도의 4일 이상 신규치료를 받은 중등도 이상의 요통근로자를 분자로 하였고, 해당년도 사업장의 종사하는 근로자 총수(과거 요통자 제외)를 분모로 간주하였다. 요통 발생군은 외상성 요통과 직업관련성 요통으로 대별하였으며, 위험요인과 질병 발생간의 관련성을 보기 위한 Cox모형에서 그 위험도를 파악하고자 할 때에는 직업성 요통만을 환자군으로 선정하였다. 결과 및 결론 . 요통 발생률은 근로자 천명당 1998년 3.1명, 1997년 8.8명, 1996년 7.8명이었다. 요통점유율의 범위는 10.99∼25.66이었다. 연령별 요통 발생률은 30대, 40대에서 높은 발생률을 보였다. 진단명에 따른 발생률은 추간판 탈출증, 염좌, 척추골절, 척추분리증, 척추협착증 순이었다 직업성 요통 발생자들의 직업적 요인을 알아보기 위하여 요통 발생 당시 작업형태를 알아본 결과, 물건을 들다가 66명(35.3%)이 발생하여 가장 큰 빈도를 차지하였고, 물건을 옮기는 과정에서 19명(10.2%)이 발생하여 2위를 차지하였고, 넘어지거나(8.6%), 물건을 당기는 자세(8.0%), 값자기 일어서다(7.5%) 순으로 요통이 발생하였다. 직업성 요통에 영향을 주는 일반적 특성 및 직업적 특성에 판한 상대위험도 및 95% 신뢰구간를 구한 결과, 요통발생에 영향을 주는 유의한 변수로는 체질량 지수(비만도), 교대여부, 중량물 취급여부였다. Objectives : This study was conducted to estimate the incidence rate, and to identify the risk factors for the occupational low back pain among shipyard workers. Methods : The study subjects consisted of 9,784 workers who were employed in a ship-building industry (excluded workers who had a history of low pack pain before 1995 or did not take periodic health examination in 1995) . The cases were 220 people who experienced back pain from January 1, 1996 to December 31, 1998. To assess risk factors for occupational low back pain, Cox propotional hazard model was used. Results : During the recent three years from 1996 to 1998, the incidence rate per 1,000 persons was 7.8 in 1996, 8.8 in 1997, and 3.1 in 1998. The main causes of work-related low back pawn were sprain, strain and disc herniation. Lifting was the most common cause of back pain (35.3%) , and carrying (10.2%) and pulling (8.0%) were followed. In Cox proportional harzard model, independent risk factors for back pain were body mass index(R.R. ; 1.54, 95% C.1. : 1.06-2.25), shift work(R.R. ; 1.65, 95% C.1. : 1.19-2.28), and lifting heavy material(R. R., 3.95, 95% C.1. : 2.29-6.82). Conclusions . This study suggests that the risk factors of back pawn In shipyard work-ers were body mass index, shift work and lifting.

      • KCI등재

        상아질 접착제를 사용한 광중합 복합레진과 Glass lonomer Cement의 전단 결합력에 관한 연구

        이제호,이종갑,권병렬,최형준 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.2

        The purpose of this study was to compare shear bond strength of composite resin using several dentin bonding agents and light cured glass ionomer cement(Fuji Ⅱ LC). 40 Bovine primary anterior teeth were used for this experiment.Labial surface of teeth were flattened.It were divided into four groups.Each group was composed of 10 teeth.The material used for this experiment were Scotchbond Multipurpose-Z-100,Allbond 2-Aelitefil,Gluma-Pekalux,light and cured glass ionomer cement(Fuji Ⅱ LC). Each of the materials was applied to the exposed surface of 10 teeth by insertion into a cylindrical shaped matrix which is 3mm diamiter and 3mm in height. The completed specimens were stored at 37℃ under 100% humidity for 24 hours:the shear bond strength of material to detin surface were measured with INSTRON universal testing machine. The results were as follows: 1.Shear bond strength to detin surface increased in oder of light cured glass ionomer cement(Fuji Ⅱ LC),Gluma,Allbond 2,Scotchbond Multipurpose. 2.Between shear bond strength of light cured glass ionomer cement(Fuji Ⅱ LC) and Allbond 2,there was statistical significace(P<0.05). 3.Between shear bond strength of light cured glass ionomer cement(Fuji Ⅱ LC) and Scotchbond Multipurpose,between shear bond strength of Gluma and Scotchbond Multipurpose,there was statistical significace(P<0.01). The shear bond strength of detin bonding agents were higher than light cured glass ionomer cement.The reason is that material and quality of detin bonding agent were enhanced.Further investigation is necessary to improve shear bond strength of light cured glass ionomer cement.

      • KCI등재

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