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( Yong Hyun Kwon ),( Sung Ho Jang ),( Mi Young Lee ),( Woo Mok Byun ),( Yoon Woo Cho ),( Sang Ho Ahn ) 영남대학교 기초/임상의학연구소 2005 Yeungnam University Journal of Medicine Vol.22 No.1
The motor recovery mechanism of a 21-year-old male monoparetic patient with cerebral palsy, who had complained of a mild weakness on his right hand since infancy, was examined using functional Magnetic Resonance Imaging (fMRI) and Transcranial Magnetic Stimulation (TMS). The patient showed mild motor impairment on the right hand. MRI located the main lesion on the left precentral knob of the brain. fMRI was performed on this patient as well as 8 control subjects using the Blood Oxygen Level Dependent technique at 1.5 T with a standard head coil. The motor activation task consisted of finger flexionextension exercises at 1 Hz cycles. TMS was carried out using a round coil. The anterior portion of the coil was applied tangentially to the scalp at a 1.0 cm separation. Magnetic stimulation was carried out with the maximal output. The Motor Evoked Potentials (MEPs) from both Abductor Pollicis Brevis muscles (APB) were obtained simultaneously. fMRI revealed that the unaffected (right) primary sensori-motor cortex (SM1), which was centered on precentral knob, was activated by the hand movements of the control subjects as well as by the unaffected (left) hand movements of the patient. However, the affected(right) hand movements of the patient activated the medial portion of the injured precentral knob of the left SM1. The optimal scalp site for the affected (right) APB was located at 1 cm medial to that of the unaffected (left) APB. When the optimal scalp site was stimulated, the MEP characteristics from the affected (right) APB showed a delayed latency, lower amplitude, and a distorted figure compared with that of the unaffected (left) APB. Therefore, the motor function of the affected (right) hand was shown to be reorganized in the medial portion of the injured precentral knob.
홍성표 ( Sung Pyo Hong ),박은영 ( Eun Young Park ),이희경 ( Hee Kyung Lee ) 영남대학교 기초/임상의학연구소 2007 Yeungnam University Journal of Medicine Vol.24 No.2S
The main purpose of this study was to provide primary informations for developing dental health program which must be necessary for cardiovascular disease patients. To conduct this study we analyses the oral health condition of cardiovascular disease patients through oral examination (DMFT index, periodontal index, oral hygiene status) and evaluate oral health behavior through questionnaires survey April 2006 to June 2006. For patients group, we select 50 cardiovascular disease patients who have hypertension, hyperlipidemia, atherosclerosis or myocardial infarction by taking the health examination for the local insured which National Health Insurance Corporation carried out at Sungju area in Gyeongsangbuk-do. And for the controls, we select 50 persons who have normal healthy condition and match the age and sex to patients group. This study showed that DMFT mean values in cardiovascular disease patients were significantly higher than that in controls (p<0.05). Decay teeth index and Filling teeth index did not differ statistically between two groups but the mean Missing teeth index was significantly higher in cardiovascular disease patients than that in controls (p<0.05). PI (Periodontal Index) mean values were significantly higher in cardiovascular disease patients than in the controls(p<0.01). In the cardiovascular disease patients, the M component of the DMFT index was found to be higher as compared to the controls. Cardiovascular disease patients lose their teeth mainly due to periodontal disease, which is supported by the increased PI mean values.