衛生昆蟲에 대한 無公害農藥(昆蟲發育沮害劑)의 殺蟲機作 및 應用技術開發硏究

金正和,李炯來,李仁煥,李容揆,崔鐘錫 충북대학교 농업과학기술연구소 1993 農業科學硏究 Vol.10 No.2

In recently, much pesticides were used for control of agricultural and medical insects. The result of using pesticides were social problem because of environmental pollutions with pesticides in urban and farm village. The environmental pollutions were very serious. This experiment was conducted to eluciated of reduce to environmental pollution bring about using pesticides (organophosphates, carbamates, pyrethroids, and insect growth regulators) for control of medical insects(house fly, Musca domestica L and mosquito, culex pipiens pallens copuillett) and carried out the method of pest control. And the result are summarized as follows. The Kyongbuk house fly strain treated with pyriproxyfen on third instar larvae were very high mortality and low emergence. When use it, at the same time, we can reduce degree of environ-mental pollution and house fly populations. Using of imidan was effective in Seoul and Chungnam house fly strains. In mosquito larvae, the efficacy of icon to chungbuk strain, propoxur to Chungnam and Chungbuk strain, imidan to Kyongbuk strain, fenthion to Chungnam strain were excellent. In result of spraying imidan and icon on adult mosquitoes, the efficacy of icon was excellent than imidan. In esterase electrophoresis, third instar larvae of Chungnam house fly strain fed on artificial diet mixed with pyriproxyfen LC50 were very high activity of -Est-αl in early stage(second day after third instar larvae fed on diet), and the activity of Est-αl was very strong in late stage(se-vents day after third instar larvae fed on diet). In Kyongbuk strain, -Est-αl and Est-αl were detected in early and late stage, and activities of and -Est-αl and Est-αl were detected almost equally in late stage. It was very characteristic in this experiment. Third instar larvae fed on diet mixed with pyriproxyfen LC95 were detected -Est-αl and Est-αl almost equally. It was believed moulting control in insects. In electrophoresis with head, thorax, abdomen of house fly adult, -Est-α2 -Est-αl, Est-αl, Est-α2, Est-α3 were detected in abdomen in susceptible strain and only -Est-αl, was net detected in thorax -Est-αl, was detected in head, thorax and abdomen of Chungbuk strain and -Est-αl was detected in head, -Est-α2 in thorax of same strain. Activities of chitinase in late instar larvae of house flies fed on artificial diet mixed with pyrip-roxyfen LC50 and LC95, in pyriproxyfen LC95, analysised low and high again with the lapse of time in Kyongbuk strain. This was believed that the activity of chitinase was became high just before emergence. The result of filter paper test with mosquitoes were very high index(265) of esterase activity in Chungnam strain among all mosquito strains. In this reason, we can suppose that used pyrip-roxyfen (IGR) in Chungnam area for control pest. In this reason, it was more reasonable made use of pyriproxyfen than other pesticide in Chungnam area.

Synergistic effect of melamine in combination with cyanuric acid on urinary tract toxicity in rats

Jong-Choon Kim, In-Chul Lee, Sung-Hwan Kim, Hyung-Sun Baek, Sung-Soo Kang 충북대학교 동물의학연구소 2013 Journal of Biomedical and Translational Research Vol.14 No.3

The present study investigated the urinary tract toxicity of melamine alone or in combination with cyanuric acid in rats. Male rats were orally administered melamine alone (800 mg/kg) or melamine plus cyanuric acid (50 mg/kg each) for 3 consecutive days. Although melamine treatment did not show any significant difference in body weight, kidney or urinary bladder weight, serum blood urea nitrogen (BUN) or creatinine levels, it caused a decrease in urinary pH and mild histopathological alterations in the kidney and urinary bladder. In contrast, co-administration of melamine and cyanuric acid induced a decrease in body weight, an increase in kidneys and urinary bladder weights, and an elevation in serum BUN and creatinine levels, which were not observed in animals treated with melamine alone. Histopathological examination showed that the incidence and severity of histopathological lesions in the kidney and urinary bladder were much higher than those in the melamine group. Urinalysis revealed an increase in urine occult blood, leukocytes and protein and a decrease in urinary pH. These results indicate that concomitant administration of cyanuric acid synergistically potentiated the urinary tract toxicity induced by melamine in rats. In this study, we first demonstrated the synergistic toxic effects of melamine in combination with cyanuric acid on urinary bladder and urinalysis in rats.

Temporal trends and in-hospital outcomes of primary percutaneous coronary intervention in nonagenarians with ST-segment elevation myocardial infarction

( Joon Young Kim ),( Myung Ho Jeong ),( Yong Woo Choi ),( Yong Keun Ahn ),( Shung Chull Chae ),( Seung Ho Hur ),( Taek Jong Hong ),( Young Jo Kim ),( In Whan Seong ),( In Ho Chae ),( Myeong Chan Cho ) 대한내과학회 2015 The Korean Journal of Internal Medicine Vol.30 No.6

Background/Aims: Data regarding the outcomes of primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) in nonagenarians are very limited. The aim of the present study was to evaluate the temporal trends and in-hospital outcomes of primary PCI in nonagenarian STEMI patients. Methods: We retrospectively reviewed data from the Korea Acute Myocardial Infarction Registry (KAMIR) from November 2005 to January 2008, and from the Korea Working Group on Myocardial Infarction (KorMI) from February 2008 to May 2010. Results: During this period, the proportion of nonagenarians among STEMI patients more than doubled (0.59% in KAMIR vs. 1.35% in KorMI), and the rate of use of primary PCI also increased (from 62.5% in KAMIR to 81.0% in KorMI). We identified 84 eligible study patients for which the overall in-hospital mortality rate was 21.4% (25.0% in KAMIR vs. 20.3% in KorMI, p = 0.919). Multivariate analysis identified two independent predictors of in-hospital mortality, namely a final Thrombolysis in Myocardial Infarction (TIMI) flow < 3 (odds ratio [OR], 13.7; 95% confidence interval [CI], 3.2 to 59.0; p < 0.001) and cardiogenic shock during hospitalization (OR, 6.7; 95% CI, 1.5 to 30.3; p = 0.013). Conclusions: The number of nonagenarian STEMI patients who have undergone primary PCI has increased. Although a final TIMI flow < 3 and cardiogenic shock are independent predictors of in-hospital mortality, primary PCI can be performed with a high success rate and an acceptable in-hospital mortality rate.

In-hospital mortality in patients with STEMI admitted during off hours

( Sung-Soo Kim ),( Myung Ho Jeong ),( Jeong Gwan Cho ),( Young Keun Ahn ),( Jong Hyun Kim ),( Shung Chull Chae ),( Young Jo Kim ),( Seung Ho Hur ),( In Whan Seong ),( Taek Jong Hong ),( Dong-hoon Choi 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1

Conflicting results exist on the outcome of off hours PCI in ST elevation myocardial infarction (STEMI). However, there were only a few studies that have focused on the clinical characteristics and outcomes of off hours PCI in STEMI. So, we studied the clinical characteristics and hospital mortality in STEMI patients treated with primary PCI during regular hours (weekdays 9:00 AM to 6:00 PM) versus off hours Weekdays 6:01 PM to 8:59 AM, weekends, and holidays) in Korea Acute Myocardial Infarction Registry. We analyzed in hospital and one year mortality among 5,665 consecutive ST segment elevation myocardial infarction patients treated with primary PCI between November 2005 to January 2008. Total 2,848 (50.2%) patients were treated during off hours. Baseline finding were similar, although regular hours patients were older. Median symptom to balloon time (304 min, IQR 175 to 750 vs. 270 min, IQR 145 to 551, p=0.001) were longer for regular hours primary PCI. Median door to balloon time (71min, IQR: 48 to 132 vs. 59 min, IQR 39 to 110 min, p=0.001) were longer for off hours pPCI. Also, Cardiac enzyme such as Max CK-MB (212.1±299.3 vs 194.7±303.4, p=0.031) and max TnI (72.6±239.5 vs. 58.9±94.4, p=0.013) were increased in off hours pPCI. However, unadjusted in hospital (6.0% off hours vs. 6.0% regular hours, p=0.946) and one year cardiac mortality (11.3% off hours vs. 11.7% regular hours, p=0.661) were comparable. In multivariate analysis, off hours primary PCI did not predict an adverse outcome. In conclusion, when primary PCI was performed within an appropriate reperfusion strategy, the clinical effectiveness of either off hours or regular hours pPCI is comparable.

내경동맥 지배 영역의 급성 허혈성 뇌졸중 환자에서 초 선택적 국소적 Urokinase주입술

김인규,김명규,김재규,조기현,김세종 대한신경과학회 1998 대한신경과학회지 Vol.16 No.5

시ㆍ도별 체육시설과 경기성적의 비교분석

최종수,유인형 忠北大學校 平生體育硏究所 1991 平生體育硏究所 論文集 Vol.5 No.-

Ⅰ) Purpose The purpose of this is efficiency study for two basic methods which are criteria of estabishing physical education's system, physical basic condition in order to secure physical activities. One of two methods which are criberia of securing physical education's system worldwidly is to consider the area of facilities per one, according to golden plan method in German, and the other is to consider the number of physical education's facilities which is needed to satisfy the demand of local physical populations by central council of physical recreation in England. Among these, I'll try to examine the method which is effectively more proper in Korea by events. Ⅱ) Method By dividing the whole nation into 14 administrative districts, 25 kinds of events studied, which is based on the data of administrative organ accounts the number of faclities in each district and the occupation rate of nation. After getting the everage of both, through relative comparing, comparative superior group of the number in the view of facilities and comparative superior group of the area in the view of facilites are divided. And by contrasting in game score of National Sports Meet for last 4 years according to districts, superior or inferior of game score among groups are given. Ⅲ) Results (1) As game score in comparative superior group of the area in the view of facilities is better, it occupys 72% of the searched events. On the other hand, comparative superior group of the number in the view of facilities occupys only 24% on the searched events. Therefore it shows that securing sufficient place for physical education by a large scale of facilities is necesary in order to improre national physical education and competition ability. (2) For the criteria of securing the physical education's facilities in district, golden plan method in German is more efficient for improving competition ability, C.C.P.R method in England is only the best alternative plan, when they have difficulty in securing the narrowing ground. (3) To put it concretely, some events including football, table tennis, wrestling, weight lifting, archery, bowling seems to be possible to use C.C.P.R method.

스티렌 폭로 근로자들의 기중 및 혈중 스티렌과 요중 만델산의 관계 분석

정호근,강성규,양정선,김기웅,이종성,조영숙,박인정 大韓産業醫學會 1994 대한직업환경의학회지 Vol.6 No.1

The concentration of styrene in air in blood and mandelic acid in urine were checked for the 60 workers with normal liver function, exposed to styrene. Styrene in air were sampled with personal air sampler at least 4 hours and analyzed by gas chromatography. Blood and spot urine were collected at the end of shift with a vacuum tube and a polythylene bottle and analyzed by gas chromatography and high performance liquid chromatography. Means of air and blood styrene and urine mandelic acid were 8.16 ppm(geometric mean), 0.199 mg/L, and 0.519 g/g creatinine, respectively. The concentration of styrene in air and mandelic acid in urine were high in the FRP factories and low in polymerization factory. Styrene in blood showed large difference by the working process. Styrene in air showed a good correlation with mandelic acid in urine(r=0.6369) and styrene in blood(r=0.6371). The mandelic acid in urine and styrene in blood corresponded to exposure of 50 ppm styrene were 0.890 g/g creatinine and 0.434 mg/L. However, hippuric acid in urine did not show any correlation with styrene in air. Urine mandelic acid excretion expected ratio showed a tendency to decrease according to obesity index and to increase with alcohol consumption.

임신성 당뇨와 임신성 내당능장애에 관한 연구

윤인숙,이종국 대구보건대학 2005 대구보건대학 論文集 Vol.25 No.-

Some of the most common metabolic disorders that are complicated by pregnancy are gestational diabetes mellitus (GDM) and gestational impaired gluscose tolerance (GIGT). Many studies on GDM and GIGT have been conducted actively in or outside of Korea recently. This study was conducted to compare maternal characteristics and pregnancy outcomes in groups of GDM or GIGT with normal pregnant women, and on 759 pregnant women delivered at the one of general hospitals in Daegu city during the period of July 1, 2001, through June 31, 2003. We performed 50gm oral glucose tolerance test (50gm GTT) to screen GIGT and GDM in 759 pregnant women at 24~28 weeks of gestation. Among 181 women with plasma glucose level over 140mg/dl in 50gm GTT, 179 women underwent 100gm oral glucose tolerance test (100gm GTT) and National Diabetes Data Group thresholds were used to diagnose GIGT and GDM. We also examined and analysed some maternal characteristics and pregnancy outcomes retrospectively in groups of GDM, GIGT, and normal pregnant women. T-test was used to determine the statistical significance. The prevalence of GIGT and GDM was 19.1% and 4.5%, respectively. The prevalence of GDM in pregnant women with over than 150mg/dl was 4 times higher than in pregnant women with 140~149mg/dl in 50gm GTT. The average age of GIGT women and GDM women was significantly higher than that of normal pregnant women(P<0.05). The prevalence of GIGT and GDM in pregnant women aged over 30 was 67.6%, 72.7%, respectively. The prevalence of GDM in pregnant women with parity over 3 in GDM group was significantly higher than that in normal pregnant women(P<0.05). In relationship between GDM prevalence and blood types of pregnant women, the pregnant women with A blood type showed the highest prevalence in GDM(66.7%). The frequency of overweight newborn in the GDM group was two times higher than that in the GIGT or normal group. One of the most common metabolic disorders that is complicated by pregnancy is GDM and pregnancy complicated with GDM showed poor maternal and neonatal outcomes. Therefore 50gm GTT must be taken in all Korean pregnant women at 24~28 weeks of gestation as well as in all foreign pregnant women.

편두통 환자의 임상 양상 및 생체전기 자율반응과의 상관성 고찰

이현종,정인태,김수영,이두익,김건식,이재동,이윤호,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objective : We had a clinical report in headache but didn't in migraine. We have planned this study in order to get the basic data of migraine in oriental medicine. Methods : The patient of 36 in migraine checked sec, age, onset, family history, severity of pain, influences of life, induced cause, clinical pain characteristics, associated symptom, treatment style, and paescription, frequency, using period of analgesics by a questionnaire and differentiated syndromes in migraine and evaluated autonomic bioelectric response recorder(ABR-2000). Results : There are 23.4% in prevalence rate of migraine. The ratio of sex is M: F=1:17. The age of an attack is the highest in thirties. The patient are the most in forties. The mean duration of illness is 12.0±9.9 years. 83.4% had a family history. 61.1% had a moderate grade in severity of pain. 77.8% selected fatigue in induced cause of migraine. 69.4% had tingling sense, nausea and vomiting in the associated symptoms. 91.7% used analgesics for treatment and 51.5% of them used analgesics voluntarily. 61.9% of them take analgesics less than once in a week. 33.6% had the phlegm syncope headache in differentiation of syndrome. In ABR-2000 results, item of graph showed low tendency mostly. Conclusions : We expected that this re port of clinical progress, differentiation of syndromes and ABR-2000 results in migraine would be used basic data by oriental medicine to treat migraine.

청소년 스포츠 활동 참여가 학교생활 만족도에 미치는 영향

김종인,김정욱 公州大學校 스포츠科學硏究所 2005 스포츠科學硏究所論文集 Vol.17 No.-

The purpose of this study was to analyse synthetically the relationship between the middle school students' participation in sports activity and the degree of satisfaction in their school life, to provide the teachers with the helpful information, and to provide the basic data for the development of physical education in school and the planning of policy. The subjects in this study were 379 students in middle schools which were located in Daejon-shi. The variables included in this study were the degree of participation in sports activity on the basis of the student's sex, of the number of family members, of the education level, the age, and the occupation of their parents, of the standard of life, and of the expense for their participation in sports activity. The data collected were analysed in the light of their participation in sports activity and the degree of satisfaction in their school life. It aimed at the comparison and analysis of the relationship of these two factors. The data were collected through the questionnaire and the statistical way used for the analysis of data were frequency analysis, one way analysis of variation(ANOVA), and multiple regression analysis. The results from the data analysis were as follows: 1. There was a meaningful difference in the middle school students 'participation in sports activity according to the following factors; sex, the education level and the occupation of their parents, and the expense for participation in sports activity. Specifically, in the factor of sex, there was not a meaningful difference in the behavioral participation and the cognitive participation. But there was a meaningful difference in the affective participation. In the factor of the education level of their parents, there was a meaningful difference in the behavioral participation. But there was not a meaningful difference in the cognitive participation and the affective participation. In the factor of the occupation of their mother, there was a meaningful difference in the cognitive participation. In the factor of the expense of participation, there was meaningful difference in the behavioral participation. 2. There was a meaningful difference in the degree of satisfaction in school life to the observance of rule according to the background factor such as the occupation of their mother. 3. There was a meaningful correlation between the participation in the sports activity and the degree of satisfaction in school life. Also, the behavioral participation and cognitive participation in sports activity has significantly influenced on the factors such as the observance of rule. The affective participation in sports activity has significantly influenced on the factors such as the students' relationship with teachers, the observance of rule. In conclusion, there was a meaningful difference in the middle school students' participation in sports activity and the degree of satisfaction in their school life according to the background factor. There was a meaningful correlation between the participation in the sports activity and the degree on satisfaction in school life.