Southern Blot Hybridization법을 이용한 악성 림프종의 면역유전형에 관한 연구

전호종,기근홍,김윤신,이미숙,이미자,장원재,장숙진,박영진,정춘해,정종훈,양성훈,이광민 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2

Immunogenotyping using gene rearrangement analysis has emerged as a precise laboratory aid in the diagnosis and classification of malignant Iymphoid neoplasms. The lineage and clonality of the malignant Iymphoid neoplasms can be identified by the demonstration of rearrangements of antigen receptor genes of the immunoglobulin and T-cell receptor genes. The analysis of the gene rearrangements on the malignant Iymphoid neoplasms are also useful as a sensitive unique clonal markers to detect early recurrence in patients with malignant Iymphoid neoplasms after treatment. To analyze the sensitivity and specificity of gene rearrangements in the diagnosis of malignant Iymphoid neoplasms. 24 cases of malignat Iymphoma were examined by Southern blot hybridization using CTβ-T cell receptor β chain gene-DNA probe and JH-immunoglobulin heavy chain gene-DNA probe. The results of the immunogenotypings using Southern blot hybridization disclosed high correlation between the immunophenotyping using immunohistochemical stain with monoclonal antibodies (B-cell Iymphoma 84.2%. T-cell Iymphoma 75% ). The analysis of the gene rearrangement of the angioimmunoblastic lymphadenopathy(AILD) and unclassifiable Iymphoma using immunohistochemical stain could resolve the monoclonality and lineage . Rearranged bands to the CTβDNA probe were observed in one case out of 2 cases of AILD. One case of unclassifiable Iymphoma showed rearranged bands to the CTβ DNA probe. There were no rearrangements in reactive follicular Iymphoid hyperplasia and paracortical Iymphoid hyperplasia. In conclusion, DNA gene rearrangement study should be applied to differentiate the clonality and cell lineage in the malignant Iymphoma with indistinctive immunophenotype.

호두의 지질함량 및 지방산조성

전종애;조규성 한경대학교 2007 論文集 Vol.39 No.-

This study investigated the compositions of lipid and fatty acid in walnuts. Four kinds of walnuts from different country of origin (South Korea, North Korea, China and America) were used. General components of walnut were 62%~72% of lipids, 16.7%~19.5% of protein, 2.5%~11.1% of carbohydrates depending on country of origin. Free and bound lipids were extracted from walnuts using Soxhlet extraction method. Contents of free and bound lipids were 63.53% and 6.51% for Korea walnut, 67.30% and 6.85% for North Korea walnut, 65.39% and 6.77% for China walnut, and 66.22% and 4.7% for America walnut, respectively. Neutral lipid, glycolipid and phospholipid were eluted from both free and bound lipid using silicic acid column chromatography(SACC). Contents of neutral lipid, glycolipid and phospholipid were 87.7~91.5%, 6.4~10.1% and 1.4~3.1% in free lipids, and 2.4~22.4%, 3.6~14.3% and 73.9~87.2% in bound lipids, respectively. Fatty acid components of free lipid were linoleic acid(60.5~63.4%), oleic acid(10.9~19.4%) and others (17~28%). Thus, unsaturated fatty acid in free acid lipid was more than 90%. Fatty acid components in bound lipid were 100% of unsaturated fatty acid as linoleic acid for Korea and China walnut, while 63% of unsaturated fatty acid for North Korea and America walnut. As a result, lipid and fatty acid compositions in walnut were little different depending on country of origin, but walnut had higher contents of unsaturated fatty acid and critical fatty acids than other foods. Walnut tissue was observed by tabletop microscope. Photographs of four kinds of walnut were all much the same in walnut tissue. Therefore, walnut seems to be a good food for prevention of disease such as arteriosclerosis and hypertension

QT연장 증후군 환자에서 Head-Up Tilt Test에 의해 유발된 Torsades De Pointes 1례

전익수,차태준,김길수,김동완,김규종,김찬욱,김성만,주승재,이재우 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

VS전동기를 대체하기 위한 저가형 VVVF 인버터의 개발

전희종,조성민,윤재식,손진근 崇實大學校 1999 論文集 Vol.29 No.1

VS(Variable Speed)-Motor is speed control method using eddy-current coupling. This method installs eddy-current coupling with constant speed driving Induction Motor and controls rotating speed through a charging change of a excitation current, particularly. VS-Motor is used widely because of simple control and wide speed range. But this method has large losses and low efficiency because of heating as slip drum in low speed region. In cooling, addition of a mechanical devices is difficult and in volume, large space is occupied. Using SCR for control, efficiency of system is low. In case of inverter, though advantage of high efficiency and high performance the price is expensive. Therefore, in this study, we developed low-cost type VVVF(Variable Voltage Variable Frequency) Inverter system for substituting VS-Motor.

정신보건관련시설 입원(소)자의 주요 정신장애 유병률 : 전국 20개 시설의 입원(소)자를 대상으로

조성진,조맹제,서동우,함봉진,홍진표,배재남,이준영,이동우,박종익,전홍진,김성주,김용익 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.6

Objectives : One of the objectives of this study is to estimate the prevalence rates of psychiatric diagnoses in the combined populations of psychiatric hospitals, psychiatric nursing facilities and homeless asylums using the Korean version of the Composite International Diagnostic Interview (K-CIDI), which is a comprehensive and fully standardized interview schedule to assess psychiatric disorders for diagnosis. The Other objective is to compare with previously studied prevalence rates of Psy-chiatric diagnoses using the results of this study. Methods : The study subjects, aged from 181o 64 years, were randomly selected from 64,582 institutionalized population of psychiatric hospitals, Psychiatric nursing facilities and homeless asylums as of 30, June, 2001. Twelve trained interviewers administered the K-CIDI to the selected respondents. A total of 1,875 respondents (male 1,194, female 681) completed the interview. Results : The lifetime and one year prevalences of any diagnosis excluding nicotine dependence · withdrawal, anxiety disorder, eating disorder, somatoform disorder were 88.2% (male 88.1%, female 88.3%), and 65.8% (male 62.7%, female 73.7%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were 78.5% (male 75.3%, female 83.7%), and 56.8% (male 51.9%, female 64.8%), respectively. The lifetime and one year prevalences of alcohol use disorder (dependence/abuse) were 26.7% (male 37.9%, female 8.3%), and 8.7% (male 12.8%, female 2.1%), respectively. The lifetime and one year prevalences of mood disorder were 18.1% (male 13.5%, female 25.8%), and 10.4% (male 7.2%,female 16.9%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were comparable with the 2001 community survey by 1.19% to 1.32%, and 0.51% to 0.61%, respectively. The lifetime and one year prevalences of schizophrenia were also comparable by 0.16% to 0.28%, and 0.16% to 0.25%, respectively. There were no significant changes of prevalence rates when correction were applied to other psychiatric diagnosis. Conclusion : The results of this study could be used for evaluating the distribution of psychiatric diagnoses in mental health related facilities and for planning mental health policies.

쇠뼈를 이용한 산미스트의 흡착 및 제거

송민종,서성은,전의찬 동신대학교 환경연구소 1997 환경연구 Vol.2 No.1

금속표면처리시설과 축전지 제조시설 둥에서 발생하는 산미스트를 효과적으로 제거하기 위하여 질산미스트 및 황산미스트를 포함하고 있는 오염된 공기를 가정과 대중음식점 등에서 폐기물로 발생되는 소의 뼈(이하 '쇠뼈')를 이용하여 흡착제거함으로써 쇠뼈의 흡착제로서의 타당성을 평가하였다. 음식점에서 폐기물로 발생하는 쇠뼈를 탈회한 후 분쇄하여 황산미스트와 질산미스트를 흡착시켜 제거하고자, 흡착제의 크기와 흡착제의 량을 달리하면서 흡착 실험한 결과 흡착제의 크기를 작게 할수록, 흡착제의 량을 많이 할수록, 질산미스트 및 황산미스트를 흡수시킨 흡수액의 pH는 증가하였으며, 질산미스트 및 황산미스트의 농도는 감소하여 각각 97.29%와 96.09%의 제거율을 나타내었다. 쇠뼈를 이용한 질산미스트와 황산미스트의 흡착제거시 제거율이 높은 것은 쇠뼈의 성분에 가장 많이 함유되어 있는 칼슘화합물과 산미스트와의 산염기 반응에 의한 것으로 분석되었으며. 이에 따라 식당이나 가정에서 폐기물로 발생되는 쇠뼈는 본 실험에서와 같이 탈회 및 파쇄과정을 거쳐 흡착능을 갖도록 하면 산미스트와 같은 특정한 오염물질을 선택적으로 제거하는 데 유용하게 사용될 수 있을 것으로 판단된다. This study was carried out to investigate the adsorptive efficiency of cow bone. And adsorbates were nitric acid-mist and sulfuric acid-mist. As particle size of cow bone was decreased, removal efficiency of nitric acid-mist increased from 10.72ppm(before treatment) to 0.29ppm(after treatment) and those of sulfuric acid-mist was increased from 222.04ppm(before treatment) to 8.67ppm(after treatment) These results suggested that cow bone is a effective adsorbent for treatment of acid-mist

심인성 색전 요인이 없는 뇌경색 환자에서 경식도 심초음파와 Acoustic Quantification을 이용한 대동맥 탄성의 평가

이종민,윤호중,임효영,박지원,김휘열,전희경,문건웅,정욱성,채장성,김재형,최규보,홍순조 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

산전 태아사망 환자에서의 Mycoplasma hominis와 Virdans streptococcus감염 1예

김윤숙,문성택,전섭,김종수,최승도,선우재근,배동한 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

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기판 레벨 플립칩의 반복 굽힘 시험기의 개발

이용성,정종설,신기훈,정성균 한국공작기계학회 2007 한국공작기계학회 추계학술대회논문집 Vol.2007 No.-

Circuit board assemblies experience various mechanical loadings during assembly and in actual use. The repeated cyclic bending can cause electrical failures due to circuit board cracks, solder interconnects cracks, and the component cracks. This paper presents a cylic bending tester developed especially for evaluating the reliability of board level flip chips under the repeated cyclic bending. The tester employs the concept of 4-point bending test and complies to JEDEC standard No. 22B113 that is intended to evaluate and compare the performance of surface mount electronic components in an accelerated test environment. The performance of the tester will be estimated through the cross check of the test results in the future work.

다층구조를 갖는 다공질규소층의 제작과 이의 물성

김영유,전종현,류성주,이영섭,이기원,최봉수 대전산업대학교 반도체기술연구소 2000 半導體技術硏究所報 Vol.2 No.-

단결정규소 웨이퍼를 15% HF에탄올 용액에서 양극 산화시켜 다공질규소를 얻는 과정에서 전류밀도와 에칭시간에 따라 굴절률이 주기적으로 변하는 다충의 다공질규소층(porous silicon multilayers)을 구현하였다. 그리고 다층의 다공질규소층(Ⅰ) 다공질규소 발광충, 또 다른 다층의 다공질규소층(Ⅱ)의 순으로 구성된 porous silicon microcavity(PSM)를 제작하고 그 물성을 조사하였다. PSM 상하에 위치한 다층의 다공질규소층의 단면을 AFM(Atomic Force Microscope)으로 조사한 결과 고굴절률과 저굴절률이 주기적으로 교차하는 층이 균일하게 형성되었으며, 중앙의 다공질규소 발광층도 균일하게 나타났다. 다층의 다공질규소층 및 다공질규소 발광층의 두께를 각각 실호파장의 1/4배 및 2배가 되도록 하였을 때 특정파장의 필터로 쓰일 수 있는 브래그 반사경(Brag reflector)의 특성이 나타났다. 또한 PSM의 발광 스펙트럼은 그 반치폭이 현저히 감소하고 발광의 세기가 크게 증가되는 경향을 보였다. By periodically varying the current density and etching time during anodic oxidation of crystalline silicon wafers in 15% HF-ethanol solution, we obtained porous silicon multilayers which have periodically varying refractive index. We fabricated the porous silicon microcavity (PSM) which consist of porous silicon multilayers(Ⅰ), active layer of porous silicon, and porous silicon multilayers(Ⅱ) and investigated its physical properties. The AFM (Atomic Force Microscope) measurement from the cross section of multilayers (Ⅰ and Ⅱ) shows uniformity of high refractive index and low index layers as well as the active layer. We observed the characteristics of Bragg reflector when the thickness of layers was 1/4 and the thickness of active layer was twice of the effective wavelength, which can be used as a filter for specific wavelength. We found the emission characteristic from the PSM, which FWHM (full width half maximum) was considerably decreased and emission intensity was increased.