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Risk factors for atypical lymph node metastasis in gastric cancer
Jinsol Jung,Sang Il Yoon,Kang-Haeng Lee,Yongjoon Won,Sa-Hong Min,Young-Suk Park,Sang Hoon Ahn,Do Joong Park,Hyung-Ho Kim 대한종양외과학회 2019 Korean Journal of Clinical Oncology Vol.15 No.2
Purpose: The present study aimed to evaluate atypical lymph node metastasis rates according to tumor depth, size, and location in patients with gastric cancer. Methods: A total of 727 gastric adenocarcinoma patients, with metastasis to 1 or 2 lymph nodes, who underwent radical gastrectomy with curative intent from May 2003 to May 2017, were enrolled in this study. The characteristics of atypical (skip or transversal) metastases were evaluated according to the following risk factors: longitudinal versus circumferential location, size, and T stage of the tumor. Results: The rates of skip and transversal metastases were 8.4% and 15.5%, respectively. Skip metastases were present throughout, regardless of the primary tumor location. On the contrary, transversal metastases of gastric cancer were most frequently observed in the lower third region (19.5%, P=0.002). When the size of the tumor is large (>4 cm), transversal metastasis was found to be significantly more common (P=0.035), compared with skip metastasis, which was less common (P=0.011). There was no significant correlation between atypical metastases and tumor depth. Conclusion: Lower and larger tumors were more likely to have transversal metastases compared with others; however, skip metastases were less common in large tumors.
Hyoung-ho Mo,Jinsol Hong,Gwan-Seok Lee,Jung-Joon Park,Doo-Hyung Lee,Kijong Cho 한국응용곤충학회 2015 한국응용곤충학회 학술대회논문집 Vol.2015 No.04
Thc climate change has the potential to significantly modify the actual distribution of insect pest with unknown consequences on agricultural systems and management strategies. In this study, Thrips palmi Karny was selected to predict distribution under climate change. T. palmi was introduced and first recorded in 1993 in Korea, and has become a serious pest of vegetable and ornamental crops. The MaxEnt was applied to T. palmi to predict its potential geographic distribution in Korea and Japan under the RCP 8.5 climate changing scenario. The MaxEnt software package is one of the most popular tools for species distribution and environmental niche modeling. The habitat prediction model of T. palmi in Korea was validated by the distribution of T. palmi in Japan. Based on the MaxEnt modeling, T. palmi would expand their potential distribution to whole Korean peninsula except the alpine region in Gangwon-do and Yanggang-do and Hamgyeongbuk-do in 2070s. Therefore, the monitoring system and management strategy for T. palmi should be reconsidered and re-evaluated.
Jinsol Hong,Gwan-Seok Lee,Jung-Joon Park,Kijong Cho 한국응용곤충학회 2017 한국응용곤충학회 학술대회논문집 Vol.2017 No.10
From simple niche models to machine learning methods, there have been intensive efforts to understand the potentialdistribution of species in last two decades. Especially in the agricultural sector, recent SDM, Species Distribution Models,studies highly enthused to predict the potential distribution of invasive species under Climate Change. Beyond the distribution,efforts are needed to assess potential risk caused by the target pest. The Shared Socio-Economic Pathways (SSPs) are scenariosfor climate change impacts and adaptation measures. We used MaxEnt model to predict potential distribution of melonthrips with two RCPs (4.5, 8.5) and three SSPs (SSP1, SSP2, SSP3) scenarios. In agricultural land, the potential distributionof melon thrips increases under climate change, but the impact is reduced with the development-oriented scenario, SSP3.
Index analysis of two different SDM technique : MaxEnt and CLIMEX
Jinsol Hong,Kijong Cho,Hyung-ho Mo,Gwan-Seok Lee,Jung-Joon Park 한국응용곤충학회 2016 한국응용곤충학회 학술대회논문집 Vol.2016 No.04
The first record of Melon thrips, Thrips palmi Karny, was in 1993 in Korea, and the species has become severe pest in agricultural industry. We used two different SDMs(Species Distribution Model) which have different approaches to analyse potential distribution of the pest species in climate change scenario, MaxEnt and CLIMEX. The MaxEnt model uses historical occurrence records with environmental variables to estimate the realized niche, and CLIMEX model simulates the fundamental niche of the object based on the seasonal phenology. In MaxEnt simulation, we reduced the number of variables to avoid multi-collinearity problem until we had no pairs with an absolute Pearson correlation coefficient higher than 0.8. BIO1(Annual Mean Temperature), BIO2(Mean diurnal range), BIO3(Isothermality), BIO4(Temperature seasonality) were finally selected as predictor, and we used 10 fold cross validation option to replicate. The averaged results were used to index analysis. The CLIMEX results, The Ecoclimate Index(EI), were also normalized in 0 to 1 scale to analysis. Under RCP 8.5 climate change scenario, in 2070s, the distribution of Thrips palmi was predicted to expand their territory overall agricultural area in Korea.
The Effect of Salinity on Starch-Derived Metabolites Released from Kimchi During Fermentation
Jinsol Song,Ju Hun Lee,Duyun Jeong,Hyun-Jung Chung 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
This study was carried out to identify and quantify sugar-related metabolites and oligosaccharides released from kimchi depending on salinities during fermentation. The kimchi adjusted to 1.0, 2.5, and 4.0% salinity was stored at 4℃ for 70 days. The sugar metabolites and oligomers in kimchi during fermentation were detected by using HPAEC-PAD system. Salt concentrations in kimchi highly influenced its starch-derived metabolites during fermentation. The lower salinity of kimchi induced relatively greater change in mannitol and fructose contents during fermentation. Kimchi samples with 1.0% salinity had greater increase in oligomers than other samples, indicating the rapid rate of fermentation. Total oligomer contents in kimchi reached the maximum value after 10 days of fermentation and they decreased continuously thereafter. Our results suggest that the quantities of starch-derived metabolites in kimchi during fermentation were highly influenced according to the salinity, which could provide useful information for kimchi industries.
Sunhwa Jung,Jinsol Cheon,Seulgi Lee,Yoo Kyoung Park 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
Personalized nutrition may be an effective strategy in the near future. We evaluated the effect of a 12-week genetic-based personalized randomized nutrition intervention on weight loss and health outcome in 62 obese adults. Physical measurements, body mass tests, blood profiles and MEQ etc before and after the study. nine obesity-related genes were assessed. Individualized nutrition counseling was performed once a week to the EG according to genetic risk factors for 12 weeks while CG received weekly SNS message. Body weight and body fat mass decreased significantly between weeks 0 and 12 in both the CG and the EG but the difference showed a greater weight loss effect in the EG than the CG (ΔCG-1.26±2.13 kg vs ΔEG-2.89±2.74 kg, p<0.05). As a result of genetic risk factors, among those with risk genes for gluttony, showed significant reduction in the total score of MEQ score (10±2.88 vs 6.14±2.19, P<0.05). CHO intake ratio was significantly decreased in the EG (53.8±1.98% to 44.3±2.16% p<0.05). In conclusion, we confirmed that genetic-based nutritional intervention can be served as an efficient tool.